Na-Young Kim, Seong-Sun Kim, Hyun Ju Lee, Dong Hwi Kim, Boyeong Ryu, Eunjeong Shin, Donghyok Kwon
{"title":"Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea.","authors":"Na-Young Kim, Seong-Sun Kim, Hyun Ju Lee, Dong Hwi Kim, Boyeong Ryu, Eunjeong Shin, Donghyok Kwon","doi":"10.24171/j.phrp.2022.0312","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0312","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to classify coronavirus disease 2019 (COVID-19)-related deaths according to whether COVID-19 was listed as the cause of death, and to investigate the differences in demographic characteristics and risk factors for COVID-19 death classifications.</p><p><strong>Methods: </strong>A total of 5,625 deaths in South Korea among patients with confirmed COVID-19 from January 20, 2020 to December 31, 2021 were selected. Excluding false reports and unnatural deaths, 5,597 deaths were analyzed. Based on death report data, deaths were classified according to whether the cause of death was listed as COVID-19 (CD) or not (NCD). The epidemiological characteristics and causes of deaths were investigated using descriptive, univariate, and multivariate statistical analyses. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to analyze the risk factors.</p><p><strong>Results: </strong>The case fatality ratio was 0.89% and increased with age. Additionally, 96.4% of the subjects had an underlying disease, and 53.4% died in winter. The proportion of NCDs was 9.3%, of whom 19.1% died at home and 39.0% were confirmed to have COVID-19 after death. Malignant neoplasms (102/416 vs. 637/4,442; OR, 1.71; 95% CI, 1.36-2.16; p<0.001) were significantly associated with NCD.</p><p><strong>Conclusion: </strong>This is the first study to analyze risk factors by cause of death using COVID-19 death report data in South Korea. These results are expected to be used as evidence for establishing a death monitoring system that can collect timely information in a new infectious disease pandemic.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 2","pages":"89-99"},"PeriodicalIF":4.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/96/j-phrp-2022-0312.PMC10211456.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9577101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comments on the article \"Time-series comparison of COVID-19 case fatality rates across 21 countries with adjustment for multiple covariates\".","authors":"Gaetano Perone","doi":"10.24171/j.phrp.2023.0072L","DOIUrl":"https://doi.org/10.24171/j.phrp.2023.0072L","url":null,"abstract":"To the Editor: I read the recently published article by Kim et al. [1]. On page 424 [1], the authors state, referring to my paper [2], that “other research using time-series cross-sectional data appears to have underestimated the impact of autocorrelation and heteroscedasticity”. However, this statement is incorrect and unfounded for 2 reasons. First, I used cross-sectional data rather than panel data, so there was no time component. The corollary is that residuals cannot be serially correlated. It makes no sense to consider autocorrelation in this case. Second, as shown in Section 5.1 of Perone [2], I safely considered heteroscedasticity in my paper: “Furthermore, since Breusch and Pagan (1979) and Shapiro and Wilk (1965) tests allowed to accept the null hypothesis of homoscedasticity and normality of residuals, models seemed well specified. However, due to the small sample, I preferred to adopt a conservative approach, by applying the HC2 correction proposed by MacKinnon and White (1985)” [3−5]. As a result, autocorrelation and heteroscedasticity issues have no bearing on the results of my paper. Notes","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 2","pages":"146"},"PeriodicalIF":4.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/f9/j-phrp-2023-0072L.PMC10211453.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9526206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hye-Jin Kim, Jieun Kim, Yoon Suk Jang, Hanul Park, Jong Mu Kim, Young Joon Park, So-Yeon Ryu, Jun Hwi Cho, So Yeong Park, Sang-Eun Lee
{"title":"Early countermeasures to COVID-19 at long-term care facilities in Gwangju Metropolitan City, Republic of Korea.","authors":"Hye-Jin Kim, Jieun Kim, Yoon Suk Jang, Hanul Park, Jong Mu Kim, Young Joon Park, So-Yeon Ryu, Jun Hwi Cho, So Yeong Park, Sang-Eun Lee","doi":"10.24171/j.phrp.2022.0293","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0293","url":null,"abstract":"<p><strong>Objectives: </strong>The coronavirus disease 2019 (COVID-19) pandemic has continued since its first detection in the Republic of Korea on January 20, 2020. This study describes the early countermeasures used to minimize the risk of COVID-19 outbreaks during cohort quarantine and compares the epidemiological characteristics of 2 outbreaks in long-term care facilities (LTCFs) in Gwangju Metropolitan City in summer 2020.</p><p><strong>Methods: </strong>An epidemiological investigation was conducted via direct visits. We investigated epidemiological characteristics, including incidence, morbidity, and mortality rates, for all residents and staff members. Demographic characteristics were analyzed using a statistical program. Additionally, the method of managing infection in LTCFs is described.</p><p><strong>Results: </strong>Residents and caregivers had high incidence rates in LTCF-A and LTCF-B, respectively. LTCF-B had a longer quarantine period than LTCF-A. The attack rate was 20.02% in LTCF-A and 27.9% in LTCF-B. The mortality rate was 2.3% (1/43) in LTCF-B, the only facility in which a COVID-19 death occurred.</p><p><strong>Conclusions: </strong>Extensive management requires contact minimization, which involves testing all contacts to mitigate further transmission in the early stages of LTCF outbreaks. The findings of this study can help inform and prepare public health authorities for COVID-19 outbreaks, particularly for early control in vulnerable facilities.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"59-65"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/32/f7/j-phrp-2022-0293.PMC10211439.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How we will reach a safer community.","authors":"Jong-Koo Lee","doi":"10.24171/j.phrp.2023.0057","DOIUrl":"https://doi.org/10.24171/j.phrp.2023.0057","url":null,"abstract":"At the end of last year, the Republic of Korea, China, and Japan responded to concerns about the increase in new coronavirus disease 2019 (COVID-19) patients and the emergence of new variants by strengthening their surveillance and quarantine measures. However, contrary to these concerns, the number of new cases and deaths decreased globally, and some have expressed the opinion that the World Health Organization (WHO) should reevaluate the declaration of a global public health crisis. However, the decision has been made to maintain the crisis status for the time being [1]. Nevertheless, in the first week of January, when the Rt value dropped below 1, the Republic of Korea implemented an exit strategy and has enforced it since January 30 [2]. The use of masks in public health facilities where a large number of people gather is now at individuals’ discretion, while their use is mandatory in public transportation. And, it is necessary to transition to a long-term strategy based on the endemicity of COVID-19. In the United States, the BXX. 1.5 variant has become predominant, but it is expected to be resolved by May 11th [3]. Therefore, the search for an exit strategy should consider which measures should be prioritized to prepare for the next pandemic. Building public trust in the safety and efficacy of currently available COVID-19 vaccines is of the utmost importance. Nationwide vaccination and booster programs have been initiated to curb the ongoing pandemic. During the vaccination campaign over the past 3 years, reports of vaccine adverse events have led to the need for research on the epidemiological relationship between vaccination and serious illnesses. To ensure scientific and objective judgments regarding this issue, the government has entrusted research on the adverse effects of COVID-19 vaccinations to the National Academy of Medicine of Korea. The study by Jeong et al. [4] published in this issue summarizes the methods used to research important adverse events following immunization; the ultimate goal of this research program is to increase the reliability of vaccines and combat vaccine hesitancy among medical professionals and the public. The second measure that must be prioritized is the improvement of governance by amending laws and regulations related to infectious diseases. After the Middle East respiratory syndrome outbreak in 2015, the government introduced a legal system that classifies reporting and quarantine methods for disease management based on the severity of each disease group. However, the severity of COVID-19 can change depending on vaccination or mutations in the virus. Thus, the government has changed the classification of COVID-19 from a level 1 disease, which requires immediate reporting, isolation, and treatment cost support, to a level 4 disease, which requires self-payment of treatment and surveillance. This adjustment of the severity level has created confusion in its management and procedural problems related to ","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"1-4"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f4/fa/j-phrp-2023-0057.PMC10211445.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hansol Yeom, Soonryu Seo, Youngsil Yoon, Jaeeun Lee, Myung-Guk Han, Deog-Yong Lee, Sun-Whan Park, Song A Park, Sook-Hyang Jeong, Jin Gwack
{"title":"The first reported hepatitis E outbreak in a food manufacturing factory: Korea, 2022.","authors":"Hansol Yeom, Soonryu Seo, Youngsil Yoon, Jaeeun Lee, Myung-Guk Han, Deog-Yong Lee, Sun-Whan Park, Song A Park, Sook-Hyang Jeong, Jin Gwack","doi":"10.24171/j.phrp.2022.0305","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0305","url":null,"abstract":"<p><strong>Objectives: </strong>On February 16, 2022, 12 cases of hepatitis E virus (HEV) infection were reported in a food manufacturing factory in Korea. The aim of this study was to identify additional cases and to determine the source of this HEV outbreak.</p><p><strong>Methods: </strong>This study was an in-depth investigation of 12 HEV immunoglobulin M (IgM)-positive cases and their demographic, clinical, and epidemiological characteristics. On-site specimens were collected from the environment and from humans, and a follow-up investigation was conducted 2 to 3 months after the outbreak.</p><p><strong>Results: </strong>Among 80 production workers in the factory, 12 (15.0%) had acute HEV infection, all of whom were asymptomatic. The follow-up investigation showed that 3 cases were HEV IgMpositive, while 6 were HEV IgG-positive. HEV genes were not detected in the HEV IgM-positive specimens. HEV genes were not detected in the food products or environmental specimens collected on-site. HEV was presumed to be the causative pathogen. However, it could not be confirmed that the source of infection was common consumption inside the factory.</p><p><strong>Conclusions: </strong>This was the first domestic case of an HEV infection outbreak in a food manufacturing factory in Korea. Our results provide information for the future control of outbreaks and for the preparation of measures to prevent domestic outbreaks of HEV infection.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"15-22"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/72/j-phrp-2022-0305.PMC10211441.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation and follow-up of pain, fatigue, and quality of life in COVID-19 patients.","authors":"Sevda Adar, Petek Şarlak Konya, Ali İzzet Akçin, Ümit Dündar, Neşe Demirtürk","doi":"10.24171/j.phrp.2022.0275","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0275","url":null,"abstract":"<p><strong>Objectives: </strong>We evaluated pain, fatigue, anxiety, depression, and quality of life in patients hospitalized for coronavirus disease 2019 (COVID-19) and observed them over a period of 3 months. We also investigated the relationship of these symptoms to age, sex, disease severity, and levels of anxiety and depression.</p><p><strong>Methods: </strong>The study included 100 confirmed COVID-19 patients (i.e., positive on a polymerase chain reaction test) between the ages of 18 and 75 years. Pain (visual analog scale [VAS]), fatigue (fatigue severity scale), anxiety, and depression (hospital anxiety and depression scales) were evaluated on the first day of hospitalization and at 1-month and 3-month follow-ups. The short form-12 questionnaire was used to measure quality of life at the 1-month and 3-month followups.</p><p><strong>Results: </strong>No differences were found in pain, fatigue, anxiety levels, depression levels, and quality of life according to disease severity. High VAS scores at hospital admission were related to continued pain at the 3-month follow-up (odds ratio [OR], 1.067; p<0.001). High VAS (OR, 1.072; p=0.003) and anxiety levels (OR, 1.360; p=0.007) were related to severe fatigue at the 3-month evaluation.</p><p><strong>Conclusions: </strong>Pain, fatigue, anxiety, and depression appear to be long-term sequelae of COVID-19 and can affect quality of life. High VAS and anxiety levels were found to be associated with long-term fatigue.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"40-50"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/be/69/j-phrp-2022-0275.PMC10211443.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Puti Sari Hidayangsih, Dwi Hapsari Tjandrarini, Noor Edi Widya Sukoco, Nikson Sitorus, Ika Dharmayanti, Feri Ahmadi
{"title":"Chronic kidney disease in Indonesia: evidence from a national health survey.","authors":"Puti Sari Hidayangsih, Dwi Hapsari Tjandrarini, Noor Edi Widya Sukoco, Nikson Sitorus, Ika Dharmayanti, Feri Ahmadi","doi":"10.24171/j.phrp.2022.0290","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0290","url":null,"abstract":"<p><strong>Objectives: </strong>Several previous studies have stated that consuming certain foods and beverages might increase the risk of chronic kidney disease (CKD). This study aimed to examine the relationships of food and beverage consumption with other risk factors for CKD.</p><p><strong>Methods: </strong>Data sources included the 2018 Basic Health Research (Riskesdas) and the National Socio-Economic Survey (Susenas), which were analyzed using a cross-sectional design. The study samples were households from 34 provinces in Indonesia, and the analysis was performed with provincial aggregates. Data were analyzed using risk factor analysis followed by linear regression to identify relationships with CKD.</p><p><strong>Results: </strong>The prevalence of CKD in Indonesia was 0.38%. The province with the highest prevalence was North Kalimantan (0.64%), while the lowest was found in West Sulawesi (0.18%). Five major groups were formed from 15 identified risk factors using factor analysis. A linear regression model presented 1 significant selected factor (p=0.006, R2 =31%). The final model of risk factors included water quality, consumption of fatty foods, and a history of diabetes.</p><p><strong>Conclusions: </strong>Drinking water quality, fatty food consumption, and diabetes are associated with CKD. There is a need to monitor drinking water, as well as to promote health education and provide comprehensive services for people with diabetes, to prevent CKD.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"23-30"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/51/10/j-phrp-2022-0290.PMC10211444.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between the empirical dietary inflammatory index and musculoskeletal pain in community-dwelling older adults: a cross-sectional study.","authors":"Mahshid Rezaei, Zahra Tajary, Zahra Esmaeily, Atefeh Eyvazkhani, Shahrzad Daei, Marjan Mansouri Dara, Mohaddeseh Rezaei, Abolghassem Djazayeri, Ahmadreza Dorosty Motlagh","doi":"10.24171/j.phrp.2022.0194","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0194","url":null,"abstract":"<p><strong>Objectives: </strong>Inflammation has been proposed to be one of the main causes of musculoskeletal pain. Diet is a lifestyle factor that plays an important role in managing inflammation; thus, we assessed the inflammatory potential of diets using the empirical dietary inflammatory index (EDII) to investigate the relationship between diet and musculoskeletal pain.</p><p><strong>Methods: </strong>This cross-sectional study included 212 elderly individuals who were selected from health centers in Tehran, Iran. Dietary intake was evaluated using a valid and reliable 147-item food frequency questionnaire. To measure the intensity of pain, a visual analogue scale was used. Multiple linear regression was applied to assess the association between the EDII and musculoskeletal pain.</p><p><strong>Results: </strong>In total, 62.7% and 37.3% of participants had mild and severe pain, respectively. The EDII values were 0.97±0.72 and 1.10±0.66, respectively, in those with mild and severe pain. A higher EDII score was associated with more intense musculoskeletal pain after adjusting for age and sex (β=0.20; 95% confidence interval [CI], 0.06-0.26; p<0.001), but not after adjustment for other confounders (β=-0.13; 95% CI, -1.54 to 0.60; p=0.39).</p><p><strong>Conclusions: </strong>Our findings indicated that higher dietary inflammation might not be associated with musculoskeletal pain in older adults. However, further investigations are required to confirm these findings.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"51-58"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/82/j-phrp-2022-0194.PMC10211446.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9528276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between face covering policies and the incidence of coronavirus disease 2019 in European countries.","authors":"Sookhyun Kim, Jiyoung Oh, Sangwoo Tak","doi":"10.24171/j.phrp.2022.0287","DOIUrl":"https://doi.org/10.24171/j.phrp.2022.0287","url":null,"abstract":"<p><strong>Objectives: </strong>This study was conducted to determine the impact of the strengthening or relaxation of face covering mandates on the subsequent national case incidence of coronavirus disease 2019 (COVID-19) in Europe as the full vaccination rate was increasing.</p><p><strong>Methods: </strong>European countries in which case incidence increased for 3 consecutive weeks were monitored and analyzed using COVID-19 incidence data shared by the World Health Organization (WHO). The epidemic trend of COVID-19 in Europe was compared with that of countries elsewhere in the world based on WHO weekly epidemiological reports from June 20 to October 30, 2021. In addition, this study provided insight into the impact of government mask mandates on COVID-19 incidence in Europe by measuring the index scores of those facial covering policies before and after mandate relaxation or strengthening. The effects of the vaccination rate and the speed of vaccination on COVID-19 incidence were also analyzed.</p><p><strong>Results: </strong>The incidence of COVID-19 after the relaxation of face covering mandates was significantly higher than before relaxation. However, no significant difference was observed in vaccination rate between countries with increased and decreased incidence. Instead, rapid vaccination delayed the resurgence in incidence.</p><p><strong>Conclusions: </strong>The findings suggest that face covering policies in conjunction with rapid vaccination efforts are essential to help mitigate the spread of COVID-19.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"31-39"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/34/j-phrp-2022-0287.PMC10211442.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi
{"title":"A framework for nationwide COVID-19 vaccine safety research in the Republic of Korea: the COVID-19 Vaccine Safety Research Committee.","authors":"Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi","doi":"10.24171/j.phrp.2023.0026","DOIUrl":"https://doi.org/10.24171/j.phrp.2023.0026","url":null,"abstract":"<p><p>With the introduction of coronavirus disease 2019 (COVID-19) vaccines, the Korea Disease Control and Prevention Agency (KDCA) commissioned the National Academy of Medicine of Korea to gather experts to independently assess post-vaccination adverse events. Accordingly, the COVID-19 Vaccine Safety Research Committee (CoVaSC) was launched in November 2021 to perform safety studies and establish evidence for policy guidance. The CoVaSC established 3 committees for epidemiology, clinical research, and communication. The CoVaSC mainly utilizes pseudonymized data linking KDCA's COVID-19 vaccination data and the National Health Insurance Service's claims data. The CoVaSC's 5-step research process involves defining the target diseases and organizing ad-hoc committees, developing research protocols, performing analyses, assessing causal relationships, and announcing research findings and utilizing them to guide compensation policies. As of 2022, the CoVaSC completed this research process for 15 adverse events. The CoVaSC launched the COVID-19 Vaccine Safety Research Center in September 2022 and has been reorganized into 4 divisions to promote research including international collaborative studies, long-/short-term follow-up studies, and education programs. Through these enhancements, the CoVaSC will continue to swiftly provide scientific evidence for COVID-19 vaccine research and compensation and may serve as a model for preparing for future epidemics of new diseases.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":"14 1","pages":"5-14"},"PeriodicalIF":4.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b5/7f/j-phrp-2023-0026.PMC10211440.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}