Hazlienor Mohd Hatta, Kamarul Imran Musa, Suhaily Mohd Hairon, Nik Mohd Hafiz Mohd Fuzi, Normaizura Mokhter, Norfaizah Sulaiman, Amutha Ayasamy, Rohani Ismail, Rohaidah Hashim, Jason Wei Jian Ng
{"title":"Temporal dynamics and forecasting of laboratory-confirmed human nontyphoidal Salmonella cases in Malaysia, 2018-2024: implications for surveillance.","authors":"Hazlienor Mohd Hatta, Kamarul Imran Musa, Suhaily Mohd Hairon, Nik Mohd Hafiz Mohd Fuzi, Normaizura Mokhter, Norfaizah Sulaiman, Amutha Ayasamy, Rohani Ismail, Rohaidah Hashim, Jason Wei Jian Ng","doi":"10.24171/j.phrp.2026.0293","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0293","url":null,"abstract":"<p><strong>Objectives: </strong>Nontyphoidal Salmonella (NTS) is a major cause of foodborne illness in Malaysia. Time-series modeling can characterize temporal patterns, although structural disruptions, nonlinear dynamics, and regional variability may affect model performance. This study aimed to characterize NTS seasonality in Malaysia, assess temporal stability, and explore model-based approaches for surveillance.</p><p><strong>Methods: </strong>Monthly laboratory-confirmed human NTS cases from national laboratory surveillance databases for 2018-2024 were analyzed using time-series models, including autoregressive integrated moving-average (ARIMA) models with Fourier terms and an exploratory hybrid ARIMA-long short-term memory (LSTM) model. Interrupted time-series analysis was used to assess structural stability. Anomalies were identified using 95% prediction intervals, and stratified modeling assessed regional heterogeneity.</p><p><strong>Results: </strong>NTS cases showed recurring annual seasonal patterns of moderate strength, with temporal variation over the study period. A significant decline occurred in March 2020 (β=-62.24 cases, p=0.001), followed by gradual recovery (β=2.71 cases/month, p<0.001), suggesting a marked coronavirus disease 2019 pandemic-related disruption and a subsequent positive post-intervention trend. The ARIMA(0,1,1)-Fourier (K=1) model outperformed conventional ARIMA, benchmark, and exponential smoothing models (root mean squared error, 42.9 vs. 51.37-108.79). The hybrid ARIMA-LSTM model provided modest additional improvement, particularly during high-case periods. Model-based anomaly detection identified deviations from expected patterns that coincided with documented outbreak-associated months. Regional heterogeneity in temporal dynamics suggested the need for surveillance strategies tailored to local epidemiological patterns.</p><p><strong>Conclusion: </strong>Parsimonious models captured most temporal patterns in NTS cases, with only modest gains from more complex approaches. Context-specific modeling strategies, model-based anomaly detection, and tiered surveillance frameworks may support more proactive NTS surveillance in Malaysia.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visibility of the Korean National Health Information Portal across search engines and generative artificial intelligence platforms: a repeated cross-sectional study.","authors":"Younglee Choi, Hee-Kyoung Nam, Belong Cho","doi":"10.24171/j.phrp.2026.0365","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0365","url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed changes in the visibility of the National Health Information Portal (NHIP), operated by the Korea Disease Control and Prevention Agency, across conventional search portals and generative artificial intelligence (AI) platforms.</p><p><strong>Methods: </strong>We analyzed 150 health-related keywords derived from NHIP traffic data, Daum search logs, and chronic disease categories across 7 platforms: Naver, Google, Bing, Daum, ChatGPT, Perplexity, and Gemini. Searches were conducted in September 2025 and February 2026; Gemini was assessed only in the second survey. NHIP exposure was defined as appearance within the top 10 organic search results, whereas AI citation was defined as explicit source attribution. Changes were tested using McNemar's test.</p><p><strong>Results: </strong>Organic search exposure for the NHIP increased on Naver (64.0% to 73.3%, p=0.018) and decreased on Bing (72.0% to 61.3%, p=0.021). AI-summary citation rates increased more substantially on Naver AI Briefing (8.0% to 62.7%, p<0.001), Bing AI Summary (6.7% to 44.7%, p<0.001), Google AI Overview (30.0% to 48.0%, p=0.001), and ChatGPT (16.7% to 38.0%, p<0.001). Gemini cited the NHIP for 96.0% of keywords. For dyslipidemia-related keywords (n=10), Google and ChatGPT showed no NHIP exposure, whereas Gemini cited the NHIP for all keywords.</p><p><strong>Conclusion: </strong>AI citation represents a new dimension of health information accessibility. To address visibility gaps and marked platform divergence, public health portals should implement a 3-level optimization strategy encompassing machine-readable infrastructure, AI-friendly content formatting, and continuous multi-platform monitoring.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Age- and sex-specific patterns in the prevalence of metabolic syndrome components in the Republic of Korea, 2014-2023: a repeated cross-sectional study of national health screening statistics.","authors":"Yu-Mi Jang, Woo-Hyeon Son","doi":"10.24171/j.phrp.2026.0195","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0195","url":null,"abstract":"<p><strong>Objectives: </strong>This study described 10-year trends in the prevalence of 5 metabolic syndrome (MetS) components and examined age- and sex-specific patterns in the Republic of Korea using aggregated national health screening statistics from 2014 to 2023.</p><p><strong>Methods: </strong>This repeated cross-sectional study used publicly available aggregated data from the National Health Screening Statistical Yearbook of the National Health Insurance Service. Annual prevalence estimates were summarized overall and by age group and sex. Linear regression descriptively summarized temporal trends. Because of a marked reduction in examinees in 2018 and a discontinuity around the 2018-2019 transition, sensitivity analyses excluding 2018 were performed.</p><p><strong>Results: </strong>From 2014 to 2023, the prevalence of abdominal obesity increased from 21.0% to 25.5%, hyperglycemia from 34.7% to 40.1%, and hypertension from 42.3% to 45.1%. Hypertriglyceridemia and low high-density lipoprotein (HDL) cholesterol appeared to decrease over the same period but showed a marked discontinuity between 2018 and 2019. Prevalence generally increased across older age groups, particularly for hypertension and hyperglycemia. Men had a higher prevalence of 4 MetS components, whereas women had a higher prevalence of low HDL cholesterol.</p><p><strong>Conclusion: </strong>MetS components showed heterogeneous temporal, age-specific, and sex-specific patterns in Korean national health screening statistics. Increases in abdominal obesity and hyperglycemia support the need for earlier age- and sex-tailored cardiometabolic prevention, whereas apparent declines in lipid-related indicators should be interpreted cautiously due to the 2018-2019 discontinuity. Because this study used aggregated repeated cross-sectional data, individual-level longitudinal studies are needed to clarify cardiometabolic risk trends in the Republic of Korea.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterogeneous shifts in cancer research topics during the COVID-19 era: evidence from topic modeling of oncology journals.","authors":"Minsoo Jung","doi":"10.24171/j.phrp.2026.0463","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0463","url":null,"abstract":"<p><strong>Objectives: </strong>The coronavirus disease 2019 (COVID-19) pandemic disrupted healthcare systems and may have influenced the direction of cancer research, particularly epidemiology and prevention research. However, empirical evidence regarding changes in research topics during the COVID-19 era remains limited.</p><p><strong>Methods: </strong>We analyzed 8,694 articles published from 2016 to 2025 in 3 journals using PubMed bibliographic data. Latent Dirichlet allocation topic modeling identified 10 thematic clusters. Differences in topic distributions between the pre-pandemic (2016-2019) and post-pandemic-onset (2020-2025) periods were assessed using the Pearson chi-square test and logistic regression. Interaction models assessed whether temporal changes differed among journals.</p><p><strong>Results: </strong>The overall distribution of topics differed significantly between the 2 periods (χ²=21.42, p=0.011). Logistic regression indicated modestly higher odds of classification as Topic 7, the representative topic of interest, during the 2020-2025 period (β=0.168, p=0.013; odds ratio≈1.18). Interaction analysis showed that this temporal change differed by journal: the interaction was significant for Cancer Epidemiology, Biomarkers & Prevention relative to the reference journal (British Journal of Cancer; β=-0.959, p<0.001) but not for European Journal of Cancer Prevention (p=0.269). Collectively, these findings indicate selective thematic reorientation rather than wholesale transformation of cancer research agendas, with changes varying according to journal scope and disciplinary focus.</p><p><strong>Conclusion: </strong>Cancer research topics shifted modestly during the COVID-19 era, with heterogeneous patterns among journals. These findings suggest that major global health crises may be associated with shifts in research agendas, although these changes may vary according to journal scope and disciplinary context.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacques Danho Monney, Clémence Marie Rose Adjoua Konan Kouassi, Yannick Konan, Edgard Valery Adjogoua, Yahaya Karamoko
{"title":"Prevalence and genotype diversity of rotavirus A in humans, animals, and environmental water samples in West Africa: a systematic review and meta-analysis.","authors":"Jacques Danho Monney, Clémence Marie Rose Adjoua Konan Kouassi, Yannick Konan, Edgard Valery Adjogoua, Yahaya Karamoko","doi":"10.24171/j.phrp.2026.0331","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0331","url":null,"abstract":"<p><strong>Objectives: </strong>To systematically review and meta-analyze the prevalence and genetic diversity of rotavirus A (RVA) in humans, animals, and environmental water samples in West Africa and to describe its geographic distribution and circulation patterns.</p><p><strong>Methods: </strong>PubMed, Scopus, Web of Science, African Journals Online, ScienceDirect, SpringerLink, JSTOR, clinical trial registries, and global health libraries were searched for observational studies published from January 1, 2010, to December 20, 2025, reporting molecular RVA genotyping data from West Africa. Two reviewers independently screened studies, extracted data, assessed risk of bias using the Joanna Briggs Institute and SYRCLE tools, and summarized genotype distributions narratively. Random-effects meta-analyses were used to estimate pooled prevalence by source category.</p><p><strong>Results: </strong>Fifty-four studies were included, comprising 21,532 samples and 2,080 RVA-positive cases. The overall pooled prevalence was 12.6% (95% confidence interval [CI], 9.9%-15.6%). Prevalence was highest in animals (19.77%; 95% CI, 5.4%-40.1%), followed by environmental water samples (14.81%; 95% CI, 3.5%-31.1%) and humans (11.37%; 95% CI, 9.0%-14.0%). Overall heterogeneity was very high (I²=97.1%). In human studies, G1P[8], G9P[8], and G2P[4] were among the most frequently detected and geographically widespread genotype combinations.</p><p><strong>Conclusion: </strong>RVA circulates widely in humans, animals, and environmental water samples across West Africa, although evidence is characterized by substantial heterogeneity, uneven geographic representation, and limited animal and environmental water data. These findings support integrated One Health surveillance, monitoring for genotype shifts, and stronger water, sanitation, and hygiene interventions.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148881859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From innovation to accountability: a risk-based paradigm for safe artificial intelligence adoption in general surgery.","authors":"Karanvir Bhinder","doi":"10.24171/j.phrp.2026.0441","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0441","url":null,"abstract":"","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indra Sivakumar, Jeevarathinam Thirumalai, Anees Ahmed Farooq Mohammed
{"title":"Long-term trends and post-pandemic deviations in cervical cancer burden in South India, 1990-2023: a Global Burden of Disease 2023 study.","authors":"Indra Sivakumar, Jeevarathinam Thirumalai, Anees Ahmed Farooq Mohammed","doi":"10.24171/j.phrp.2026.0252","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0252","url":null,"abstract":"<p><strong>Objectives: </strong>Cervical cancer remains a major public health challenge in India despite advances in prevention through human papillomavirus (HPV) vaccination and screening. Although national estimates indicate gradual declines, marked regional disparities persist, and coronavirus disease 2019-related disruptions may have affected recent disease trajectories. This study assessed long-term trends, post-pandemic deviations, and progress toward World Health Organization (WHO) elimination targets in South India.</p><p><strong>Methods: </strong>This population-based observational analysis used Global Burden of Disease Study 2023 estimates for women aged 30-69 years in South India from 1990 to 2023. Pre-pandemic trends and counterfactual projections were evaluated, and age-standardized incidence rates (ASRs) were descriptively compared with the WHO elimination threshold of ≤4 cases per 100,000 woman-years.</p><p><strong>Results: </strong>Age-standardized cervical cancer incidence and mortality declined until the early 2010s but remained above national and global rates. Thereafter, declines stagnated and reversed. In 2023, incidence ranged from 26.1 per 100,000 women in Kerala to 65.8 in Telangana; all states exceeded the WHO threshold based on these ASRs. Observed rates exceeded counterfactual projections, but uncertainty envelopes included zero for every location and outcome. Thus, the findings are consistent with possible post-pandemic disruption to cervical cancer services rather than statistically demonstrated excess burden, and this ecological comparison cannot establish causality. Disability-adjusted life-year rates were highest among women aged 50-69 years.</p><p><strong>Conclusion: </strong>South India appears to have experienced a recent loss of momentum in cervical cancer control. Strengthening HPV vaccination coverage, expanding screening, and improving the resilience of cancer prevention services are essential for accelerating progress toward elimination targets.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between park accessibility and multimorbidity in Korean older adults: a cross-sectional study.","authors":"Min-Ju Seo, Jin Young Nam","doi":"10.24171/j.phrp.2026.0296","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0296","url":null,"abstract":"<p><strong>Objectives: </strong>Adequate physical activity is essential for promoting healthy life expectancy among older adults. Park accessibility is an important environmental determinant of physical activity and may support multimorbidity management in this population. However, evidence on the association between park accessibility and multimorbidity remains limited, particularly in nationally representative Korean samples. This study examined the association between park accessibility and multimorbidity among older Korean adults.</p><p><strong>Methods: </strong>This cross-sectional study analyzed data from 10,078 individuals aged ≥65 years who participated in the 2023 National Survey of Older Koreans. Multiple logistic regression was used to examine the association between park accessibility and multimorbidity after adjustment for covariates. Stratified analyses assessed this association by physical activity level, and additional logistic regression analyses evaluated associations between park accessibility and common chronic diseases.</p><p><strong>Results: </strong>The prevalence of multimorbidity among older adults was 64.8%. After adjustment for all covariates, older adults living 30-59 minutes' walking distance from a park had higher odds of multimorbidity than those living <15 minutes from a park (adjusted odds ratio, 1.33; 95% confidence interval, 1.12-1.59). Among the common chronic diseases examined, hypertension was significantly associated with park accessibility.</p><p><strong>Conclusion: </strong>Greater park accessibility may support physical activity and green-space exposure and may thereby contribute to multimorbidity management and healthy life expectancy among older adults.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chikungunya fever among Japanese travelers: monthly and yearly trends in imported cases, 2011-2023.","authors":"Ryuichi Yano, Hiroshi Nishiura","doi":"10.24171/j.phrp.2026.0049","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0049","url":null,"abstract":"<p><strong>Objectives: </strong>Chikungunya poses an increasing threat to people living in endemic areas and to travelers from non-endemic regions. This study descriptively characterized imported chikungunya cases in Japan and explored the relationship between local incidence in destination areas and infection risk among Japanese travelers.</p><p><strong>Methods: </strong>First, the descriptive features of imported chikungunya cases in Japan from 2011 to 2023 were examined. Second, monthly and yearly trends in the incidence of imported chikungunya cases among Japanese travelers were compared by destination with incidence in the corresponding destination country. Third, destination-specific incidence among Japanese travelers was compared between high- and low-transmission seasons in each destination country.</p><p><strong>Results: </strong>Of 155 imported chikungunya cases in Japan during 2011-2023, 112 (72.3%) were associated with travel to Myanmar, India, Indonesia, the Philippines, or Thailand. The yearly chikungunya importation rate among Japanese travelers returning from Indonesia and Thailand was correlated with the corresponding rate among local residents. The monthly incidence of imported cases during the high-transmission season was 12.3, 7.4, 12.0, and 4.0 times higher than that during the low-transmission season among travelers returning from Myanmar, India, Indonesia, and the Philippines, respectively.</p><p><strong>Conclusion: </strong>The risk of imported chikungunya infection among Japanese travelers reflected the local epidemiology of chikungunya in destination countries, including both seasonal and long-term patterns. Imported-case data may support risk assessment in destination countries and contribute to traveler-specific prevention, improved diagnosis, and a reduced risk of autochthonous outbreaks.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Economic effectiveness of training personnel for infectious disease response and improving information systems in Republic of Korea: a cost-benefit analysis.","authors":"Sunung Moon, Sangwon Lee, Yunhyung Kwon, Chaeeun Lee, Nahyun Kwon","doi":"10.24171/j.phrp.2026.0019","DOIUrl":"https://doi.org/10.24171/j.phrp.2026.0019","url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed the economic value of 2 major initiatives within the national infectious disease response system of the Korea Disease Control and Prevention Agency (KDCA): the Training Programs for Public Health Workforce (TPPHW) and the Infectious Disease Information System (IDIS).</p><p><strong>Methods: </strong>We developed a structured estimation model to quantify the economic benefits of pandemic preparedness investments and applied it to the KDCA's TPPHW and IDIS. The model incorporated parameters elicited from 29 senior officials into a cost-benefit analysis (CBA) framework, from which we calculated the net present value (NPV) and benefit-cost ratio (BCR) over a 10-year period, with sensitivity analyses.</p><p><strong>Results: </strong>Both initiatives yielded positive net benefits under baseline assumptions, although the margin was substantially greater for workforce training than for the information system. At the assumed discount rate of 4.5%, the CBA yielded a BCR of 2.120 and an NPV of 27.2 billion Korean won (KRW) for TPPHW. For IDIS, the corresponding values were a BCR of 1.071 and an NPV of 2.7 billion KRW. Sensitivity analysis showed that workforce training remained economically justified across all scenarios, whereas the information system remained viable only under more favorable assumptions.</p><p><strong>Conclusion: </strong>This study contributes to the literature by systematically applying CBA to infectious disease preparedness in the Republic of Korea. The findings support continued investment in skilled workforce training and integrated information infrastructure for future pandemic preparedness. The study is limited by its reliance on expert-elicited parameters and its focus on monetary benefits, excluding health outcomes such as disability-adjusted life years and quality-of-life improvements.</p>","PeriodicalId":38949,"journal":{"name":"Osong Public Health and Research Perspectives","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}