Iranian Journal of Psychiatry最新文献

{"title":"The Genetic Landscape of Autism in Iran: A Systematic Review.","authors":"Delaram Barfeh, Armita Shahesmaeilinejad, Mahin Eslami Shahrbabaki, Anahita Karamooz, Fatemeh Shekari, Azam Zare Arashlouei","doi":"10.18502/ijps.v21i1.20567","DOIUrl":"https://doi.org/10.18502/ijps.v21i1.20567","url":null,"abstract":"<p><p><b>Objective:</b> Autism Spectrum Disorder (ASD) is a genetically heterogeneous neurodevelopmental condition involving multiple genes. This study aimed to comprehensively review the genetic landscape of ASD in the Iranian population, identifying gene variants associated with increased risk, to facilitate improved diagnosis and targeted interventions. <b>Method</b> <b>:</b> A systematic review and meta-analysis were conducted on genetic association studies of ASD in Iran up to August 2025. Comprehensive searches were performed in PubMed, Scopus, Web of Science, and Persian databases using relevant keywords. Quality assessment was performed using the Joanna Briggs Institute critical appraisal tools. Meta-analyses were carried out using Review Manager software, assessing heterogeneity and publication bias. Protein-protein interaction networks were constructed via STRING and analyzed with Cytoscape to identify key hub genes and enriched neurodevelopmental pathways. <b>Results:</b> In this study, genes RORA, MTRR, MTR, Reelin, VDR, VMAT1, ACE I/D, MOCOS, HOTAIR, ANRIL, RIT2, MMP-9, GRM7, FOXP3, and GRIN2B showed significant associations with the occurrence of autism. Findings reinforce associations between multiple gene polymorphisms, especially RORA rs4774388 and MOCOS rs594445, with the risk of ASD. <b>Conclusion:</b> This systematic review and meta-analysis emphasize the multifactorial genetic contributions to ASD in the Iranian population, highlighting key risk loci and neurodevelopmental pathways. The findings underscore the importance of integrating genetic, epigenetic, and environmental factors for understanding ASD etiology and developing population-tailored diagnostic and therapeutic strategies. Future studies employing larger cohorts and multi-omics approaches are warranted to further elucidate the complex genetic architecture of ASD in diverse ethnic groups.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"21 1","pages":"80-96"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic and Family Factors Associated with Body Image Dissatisfaction among Adolescents in Tehran.","authors":"Mohammad Reza Mohammadi, Zahra Zamani, Ali Najafi, Zahra Kafami, Ali Yavari, Shahin Akhondzadeh","doi":"10.18502/ijps.v21i1.20566","DOIUrl":"https://doi.org/10.18502/ijps.v21i1.20566","url":null,"abstract":"<p><p><b>Objective:</b> Body image dissatisfaction is a prevalent concern among adolescents, with potential implications for mental and physical health. Understanding its correlates in diverse cultural contexts, such as Iran, is crucial for developing targeted interventions. This study aimed to investigate the demographic {Body Max Index (BMI), gender, etc.} socioeconomic status and family structure associated with body image dissatisfaction in a sample of adolescent students in Tehran, Iran. <b>Method</b> <b>:</b> This cross-sectional study included 1,430 students (grades 7, 8 and 9) from randomly selected schools in Tehran. Body image dissatisfaction was assessed using a validated international questionnaire measuring demographics, body perceptions, eating patterns, and family structures. Self-reported weight height values were used to calculate BMI. Misperceived body status was defined as discordance between self-perceived image and actual BMI category. Statistical analyses included chi-square tests, t-tests, and multivariate regression (SPSS v26). <b>Results:</b> A total of 1, 430 participants completed the questionnaires and the mean age of participants was (14.13 ± 1.2), and 54.8% were females and 785 males (54.9%). The findings revealed that 59.1% of adolescents misperceived their body status. Female gender (OR = 1.5, 95% CI: 1.18-1.90, P = 0.001), lower family SES (socioeconomic status) (OR = 4.27, 95% CI: 1.87-9.74, P < 0.001), higher BMI (OR = 1.09, 95% CI: 1.06-1.12, P < 0.001), and non-biological family structures (OR = 0.79, 95% CI: 0.26-2.3, P = 0.05) were significantly associated with body dissatisfaction. Students living with stepparents or relatives reported lower body satisfaction compared to those living with biological parents. These findings underscore the importance of gender, socioeconomic status, family structure, and BMI as key factors influencing body image dissatisfaction among adolescents. <b>Conclusion:</b> These findings highlight the importance of gender, socioeconomic status and family structure in body dissatisfaction among adolescents. Importantly, these findings reflect the heightened challenges facing youth in the post-COVID-19 era, during which lifestyle changes, increased social media exposure, and altered social interactions have intensified body image concerns. Further research is needed to explore this correlation in more detail and to develop culturally appropriate interventions to promote positive body image.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"21 1","pages":"69-79"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Qualitative Exploration of Stakeholder Perceptions of Schizophrenia.","authors":"Mamnuah Mamnuah, Wawan Febri Ramdani, Dwi Prihatiningsih, Dwi Sri Handayani, Dwi Ernawati, Noorwahyu Trihidayati, Rofi Istifaroh","doi":"10.18502/ijps.v21i1.20565","DOIUrl":"https://doi.org/10.18502/ijps.v21i1.20565","url":null,"abstract":"<p><p><b>Objective:</b> Schizophrenia is a severe mental disorder associated with substantial social stigma that impedes patients' access to quality care and social support. In Indonesia, where cultural and religious beliefs strongly influence mental health perceptions, stakeholders' attitudes critically shape responses to this condition. This study explored how various stakeholder groups perceive schizophrenia in Indonesia. <b>Method</b> <b>:</b> A phenomenological qualitative design was employed with 29 participants (families, healthcare workers, and policymakers) selected through purposive sampling in Yogyakarta, Indonesia. Data were collected through face-to-face semi-structured in-depth interviews (60-90 minutes), audio-recorded and supplemented by direct observations. Interview transcripts were analyzed using thematic analysis with triangulation and member checking to ensure data validity. <b>Results:</b> Five main themes emerged: (1) healthcare workers demonstrated clinical understanding, while families showed experiential knowledge; (2) stakeholders recognized multifactorial causation combining genetic and environmental factors; (3) realistic expectations focused on symptom management rather than cure; (4) persistent cultural stigma, rooted in supernatural beliefs, hindered help-seeking; (5) and collaborative family-healthcare worker partnerships were essential for patient stability. <b>Conclusion:</b> This study provides novel insights into Indonesian stakeholders' perspectives on schizophrenia, revealing culturally-specific stigma patterns rooted in supernatural beliefs-a factor understudied in Southeast Asian contexts. Findings inform development of targeted anti-stigma interventions and integrated care models that leverage family-healthcare worker collaboration to improve patient outcomes in Indonesia's mental health system.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"21 1","pages":"59-68"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Challenges and Consequences of Maternal Parenting in the Age of Digital Children (Digital Baby Syndrome): A Grounded Theory Study.","authors":"Hassan Zareei Mahmoodabadi, Zeinab Sadat Shamrizi, Mohammad Reza Mohammadi","doi":"10.18502/ijps.v21i1.20562","DOIUrl":"https://doi.org/10.18502/ijps.v21i1.20562","url":null,"abstract":"<p><p><b>Objective:</b> One of the important issues affecting parenting is how parents navigate the digital age. The digital age has created the concept of ideal parenting, which can unintentionally distance parents from the real world, preventing them from recognizing their children's primary needs. Consequently, children may seek alternative spaces to fulfill their needs, which often involve virtual and unreal content, leading to negative effects and consequences. Thus, this study aims to explore the challenges and consequences of parenting in the age of digital children. <b>Method</b> <b>:</b> This qualitative research was based on grounded theory. The study environment included mothers with children engaged with digital devices in Yazd Province, Iran. Based on theoretical, purposive, and snowball sampling, in-depth, semi-structured interviews were conducted, and 12 participants were selected until theoretical saturation was reached. Data were analyzed using MAXQDA software. <b>Results:</b> Data were analyzed using Strauss and Corbin's grounded theory method, including open, axial, and selective coding. From open coding, 450 initial codes were extracted; axial coding yielded 23 subcategories, and selective coding resulted in four main categories: ideal parenting, immersion in cyberspace, lack of self-differentiation (fusion), and unbridled cyberspace. The core category of the digital child was also identified. <b>Conclusion:</b> Parenting in the digital age can prevent parents from connecting with the real world and understanding the child's primary needs, directing the child toward spaces away from reality. Many parents are unaware of the challenges and potential problems caused by such spaces.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"21 1","pages":"28-35"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Persian Version of the Comprehensive Autism Trait Inventory (CATI).","authors":"Karim Abdolmohamadi, Asgar Alimohamadi, Jafar Samari Safa","doi":"10.18502/ijps.v20i4.19687","DOIUrl":"10.18502/ijps.v20i4.19687","url":null,"abstract":"<p><p><b>Objective:</b> The present study aimed to culturally adapt and psychometrically evaluate the Comprehensive Autism Trait Inventory (CATI) for use within the Iranian society, thereby facilitating cross-cultural research on autistic traits. <b>Method</b> <b>:</b> This cross-sectional survey included 1,013 Iranian adults (70.1% female), aged 15 to 50 years (M = 24.91, SD = 5.47), recruited through convenience sampling. The translation of the CATI into Persian was developed based on a carefully implemented forward and backward translation procedure through bilingual experts. Discrepancies were resolved by a panel of psychologists and psychometricians to ensure semantic and conceptual equivalence. The broad autism phenotype questionnaire (BAPQ), a tool designed to measure traits associated with the broad autism phenotype, was also administered to measure convergent validity. In order to assess internal consistency, Cronbach's alpha was calculated, while construct validity was evaluated through confirmatory factor analysis (CFA) and Pearson correlations with BAPQ scores. <b>Results:</b> CFA confirmed that all items aligned meaningfully with their intended factors, supporting the persian CATI's six-factor structure and indicating a good model fit (CFI = 0.93; RMSEA = 0.047; χ² / df = 3.25; GFI = 0.90; SRMR = 0.059). The average variance extracted (AVE) was 0.45 for both the components and the overall scale. Correlations between CATI subscales and the BAPQ ranged from 0.03 to 0.40, demonstrating acceptable convergent and divergent validity. The reliability of the six-factor model was verified by Cronbach's alpha (0.84) and McDonald's omega (0.82). <b>Conclusion:</b> The Persian version of the CATI shows sound psychometric properties for evaluating autistic traits in the Iranian population. These findings support utility of CATI in research settings and highlight the importance of culturally adapted assessment tools for improving diagnosis and intervention across diverse contexts.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"20 4","pages":"501-511"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12712412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Real Deviance: Misrepresentation of Science and the Persistence of Homophobic Ideology - A Rebuttal to Daftari and Khaleghi.","authors":"Gonzalo Renato Quintana, Jaime Barrientos","doi":"10.18502/ijps.v20i4.19678","DOIUrl":"10.18502/ijps.v20i4.19678","url":null,"abstract":"","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"20 4","pages":"427-428"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12712389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embodied Self and Metaphor Comprehension Predict Comprehension of Boundary Concept in Patients with Schizophrenia.","authors":"Majid Mahmoud Alilou, Fatemeh Bagheri, Abbas Bakhshipour Roudsari, Ali Asgharzadeh","doi":"10.18502/ijps.v20i4.19686","DOIUrl":"10.18502/ijps.v20i4.19686","url":null,"abstract":"<p><p><b>Objective:</b> The embodied self refers to the sense of self intertwined with the physical body and its experiences, which is impaired in schizophrenia. Comprehension of metaphors that are cognitive tools to help the comprehension of abstract ideas is also impaired in patients with schizophrenia. The Conceptual Metaphor Theory (CMT) links embodied experiences and metaphors to boundaries, indicating that these disruptions may lead to difficulties in understanding boundaries in schizophrenia. This study explores the role of embodied self and metaphor comprehension in predicting boundary concept comprehension in patients with schizophrenia. <b>Method</b> <b>:</b> This study employed a cross-sectional correlational design to examine the relationships among variables. The current study recruited 85 Male patients who were diagnosed with schizophrenia (mean age = 47.84 years, SD = 7.58) through a convenience sampling method. All participants completed the Embodied Sense of Self scale, the Montreal Evaluation of Communication (MEC) Metaphor subtest, and a researcher-developed questionnaire assessing comprehension of the boundary concept. Multiple linear regression analyses were applied to assess the associations between the embodied self, metaphor comprehension, and understanding of the boundary concept. <b>Results:</b> The suggested Model predicts 50% of the total variance (P < 0.01, R2 = 0.50). Metaphor comprehension predicts boundary concept understanding (β = 0.67, P ≤ 0.01, R2 = 0.50), while the embodied self (β = -0.13, P = 0.1, R2 = 0.50) does not. <b>Conclusion:</b> Our findings indicate that impairments in metaphor comprehension are significantly related to the understanding of boundary concepts in schizophrenia, while no such relationship was observed with the embodied self. These results highlight the role of metaphorical cognitions in boundary perception, potentially extending to issues with the self-other boundary and representing relations of self-other boundary disturbances and Metaphorical cognition.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"20 4","pages":"490-500"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12712425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health Consequences of War: Lessons from Recent Conflicts and Implications for All, Specifically Iranians.","authors":"Mohammad Reza Mohammadi, Ali Khaleghi","doi":"10.18502/ijps.v20i4.19677","DOIUrl":"10.18502/ijps.v20i4.19677","url":null,"abstract":"","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"20 4","pages":"424-426"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12712395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mediating Role of Alexithymia in the Relationship between Maladaptive Object Relations Patterns and Depression.","authors":"Javad Bagheri Salami, Zeinab Jangi","doi":"10.18502/ijps.v20i4.19685","DOIUrl":"10.18502/ijps.v20i4.19685","url":null,"abstract":"<p><p><b>Objective:</b> Depression is a prevalent psychological condition that severely impacts quality of life. Psychodynamic theories highlight early interpersonal experiences and maladaptive object relations as key factors in vulnerability to psychopathology. Alexithymia, characterized by difficulty identifying and expressing emotions, is a transdiagnostic risk factor strongly linked to depression. This study examines the mediating role of alexithymia in the relationship between maladaptive object relations and depression. <b>Method</b> <b>:</b> This cross-sectional study used a path-analysis method. A total of 245 dormitory students (145 males and 100 females) from Iran University of Medical Sciences were selected via two-stage cluster sampling. Data were collected using the Bell Object Relations and Reality Testing Inventory (BORRTI), Toronto Alexithymia Scale (TAS-20), and Beck Depression Inventory-Short Form (BDI-S). Pearson correlation, regression analysis, and the Sobel test were conducted using SPSS version 20. <b>Results:</b> Path analysis showed significant direct effects of maladaptive object relations (alienation, insecure attachment, egocentricity, social incompetence) on both alexithymia (β = 0.395-0.444, P < 0.001) and depression (β = 0.365-0.562, P < 0.001). Alexithymia also directly affected depression (β = 0.176-0.287, P ≤ 0.003). Indirect effects of alexithymia in the relationship between object relations and depression ranged from 0.077 to 0.113, with all paths significant per the Sobel test. <b>Conclusion:</b> Alexithymia significantly mediates the relationship between maladaptive object relations and depression, suggesting that early unhealthy relational patterns may foster depression by impairing emotional awareness. Therapeutic interventions should focus on enhancing emotional processing to promote sustainable recovery.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"20 4","pages":"482-489"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12716096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationships of Attitudes toward Eating and Eating Behaviors with Invalidating Childhood Environment in Adults: The Mediating Role of Self-Compassion, Distress Tolerance, and Impulsivity.","authors":"Farima Rahmati, Simin Alipour Marjghal, Maryam Aaslzaker, Fatemeh Rafeie, Mohammad Noori, Imaneh Abasi","doi":"10.18502/ijps.v20i4.19682","DOIUrl":"10.18502/ijps.v20i4.19682","url":null,"abstract":"<p><p><b>Objective:</b> Eating disorders (EDs) are prevalent in adulthood and often originate in adolescence, influenced by various psychological factors, including childhood experiences. This research investigated how self-compassion, distress tolerance, and impulsivity function as mediators between early experiences of emotional invalidation during childhood and individuals' eating patterns and attitudes in adulthood. <b>Method</b> <b>:</b> The study involved 1,217 students (86.2% female), recruited through convenience sampling. Participants completed standardized questionnaires assessing eating behaviors, eating attitudes, self-compassion, distress tolerance, and impulsivity. The proposed model was tested using structural equation modeling (SEM). <b>Results:</b> Impulsivity and self-compassion significantly mediated the relationship between childhood invalidation and both eating behavior (β = 0.161, P < 0.05) and eating attitude (β = 0.077, P < 0.01). Distress tolerance did not serve as a significant mediator in the model. Invalidating childhood environment was directly related to impulsivity (β = 0.303, P < 0.001) and self-compassion (β = -0.350, P < 0.001). Self-compassion and impulsivity were significant predictors of eating behavior and attitudes. <b>Conclusion:</b> Childhood experiences of invalidation contribute to maladaptive eating behaviors and attitudes through the mediating roles of impulsivity and self-compassion. Notably, impulsivity had a stronger indirect effect on both outcomes compared to self-compassion. The results indicate that fostering self-compassion and managing impulsive tendencies may serve as important focal points for interventions designed to prevent or treat eating disorders.</p>","PeriodicalId":38866,"journal":{"name":"Iranian Journal of Psychiatry","volume":"20 4","pages":"452-462"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12712390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}