{"title":"[A CASE REPORT OF VESICAL CALCULUS FORMATION WITH CHROMIC CATGUT AT THE URETEROVESICAL ANASTOMOTIC SITE 28 YEARS AFTER RENAL TRANSPLANTATION].","authors":"Michikata Hayashida, Akihiro Yano, Takayoshi Fuu, Naoto Tanaka, Kiichi Hagiwara, Shoichi Nagamoto, Kazushige Sakaguchi, Toshikazu Okaneya, Yasuo Ishii, Shinji Urakami","doi":"10.5980/jpnjurol.112.49","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.49","url":null,"abstract":"<p><p>A 69-year-old man underwent renal transplantation due to chronic renal failure of unknown cause in 1991. Furthermore, in 2012 he again underwent renal transplantation due to renal graft dysfunction with focal segmental glomerulosclerosis. After the second renal transplantation, his renal function has been stable. In 2019, he presented to the urology department with gross hematuria. Cystoscopy revealed a 2 cm vesical calculus at the dome of the bladder near the right lateral wall. Therefore, we performed transurethral lithotripsy using the holumium laser method. The vesical calculus was crushed, revealing a suture at the center, suggesting the suture as the cause. We tried to remove the suture during operation, however, it was impossible. Although the remaining suture posed a risk for calculus development, there has been no recurrence of a calculus for 6 months after the operation. This case reports a vesical calculus at the ureterovesical anastomotic site, wherein the core was an absorbable suture used during the initial renal transplantation. It should be taken into consideration that there is a possibility of anastomotic calculus occurrence with absorbable sutures, even long after renal transplantation.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 1","pages":"49-52"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39694764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A CASE OF PERSISTENT RETROPERITONEAL ABSCESS CAUSED BY RESIDUAL SILK SUTURE AFTER SURGERY].","authors":"Masahiko Inahara, Miki Ishibashi, Tatuo Igarashi, Yuji Oshima","doi":"10.5980/jpnjurol.112.25","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.25","url":null,"abstract":"<p><p>A 61-years-old male with left renal cancer and ipsilateral adrenal tumor had carried out partial nephrectomy and adrenalectomy via open retroperitoneal approach. Fourteen days after surgery, febrile reaction occurred and CT revealed an abscess developed in the retroperitoneal space. Open drainage and lavage of retroperitoneal space had performed, and irrigation of drainage tract had been continued for persistent flow of purulent discharge from abscess touching upper pole of the kidney for about 4 months. After 127 days of second surgery, two clusters of silk suture were sucked out during irrigation. Soon after the episode, flood of purulent discharge from drainage tract was ceased and retroperitoneal abscess was diminished drastically. It should be in mind that the foreign boy like silk suture used during surgery would cause persistent retroperitoneal abscess.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 1","pages":"25-28"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39834795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[EFFECTIVENESS AND SAFETY OF TRANSURETHRAL ENUCLEATION WITH BIPOLAR (TUEB) IN THE ELDERLY (OVER 80 YEARS OLD)].","authors":"Makoto Taguchi, Takao Mishima, Kaneki Yasuda, Hidefumi Kinoshita, Tadashi Matsuda","doi":"10.5980/jpnjurol.112.117","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.117","url":null,"abstract":"<p><p>(Objective) The number of elderly people is increasing in Japan, and there are many reports on the safety and effectiveness of treatment for the elderly. As the number of elderly men with benign prostatic hyperplasia is increasing, it is necessary to consider surgical treatment for the elderly. We analyzed the treatment outcome of transurethral enucleation with bipolar (TUEB), and investigated the effectiveness and safety of TUEB in the elderly (over 80 years old) at Saiseikai Izuo Hospital. (Methods) In total, 47 patients who underwent TUEB were enrolled. The patients were divided into two groups by age (< 80 years old group and ≥ 80 years old group). We investigated the factors related to the occurrence of complications by multivariate analysis. (Results) Mean duration of surgery was 107.8 min and 85.8 min (p=0.11) in the < 80 group and the ≥ 80 group, respectively. Mean resected prostate weight was 33.9 g and 31.0 g (p=0.61) and mean hemoglobin loss was 1.29 g/dL and 0.66 g/dL (p=0.01), respectively. Hemoglobin loss was significantly lower in the over 80 years old group. Complications were observed in six patients (24.0%) in the under 80 years old group and two patients (9.1%) in the over 80 years old group; however, there was no significant difference between the two groups (p=0.17). Fever was a complication in the over 80 years old group. In multivariate analysis, operative time was significant predictive factor for complications (odds ratio: 1.03, 95% confidence interval: 1.00-1.06, p=0.03) and, age was not significant predictive factor. (Conclusion) This study shows that TUEB for patients over 80 years old is effective and safe.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 3","pages":"117-122"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40523822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[REPARATIVE SURGERY OF PRESSURE-REGULATING BALLOON HERNIA AFTER ARTIFICIAL URINARY SPHINCTER REPLACEMENT: A CASE REPORT].","authors":"Yuma Waseda, Minato Yokoyama, Masahiro Toide, Yutaka Tokairin, Yasuhisa Fujii","doi":"10.5980/jpnjurol.112.150","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.150","url":null,"abstract":"<p><p>A 74-year-old male with post-prostatectomy incontinence underwent artificial urinary sphincter replacement due to device malfunction. Three months after the replacement surgery, he presented for a consultation due to a bulging area in his lower abdomen. Computed tomography revealed a hernia of the pressure-regulating balloon (PRB), while the device was working well. In the reparative surgery, reopening the lower abdominal incision, the PRB was carefully restored to its previous position after creating a sufficient submuscular space. As the rectus abdominis fascia showed an adequate strength, the fascia was tightly sutured without using a prosthetic mesh. Thereafter, the patient has been free from incontinence for two and a half years without hernia recurrence. Given the mechanical nature of the device, replacement surgery is sometimes required over time. Tissue fragility due to repetitive surgeries and increasing ambient pressure due to space reduction derived from the PRB deflation could cause PRB hernia. Such cases can be treated under careful manipulation without damaging the device. Considering the future potential need for repeated surgery, it would be preferable not to use prosthetic mesh, as it can cause dense adhesion.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 3","pages":"150-153"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40539560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[LINGUISTIC VALIDATION OF JAPANESE VERSION OF THE VULVOVAGINAL SYMPTOMS QUESTIONNAIRE (VSQ)].","authors":"Hikaru Tomoe, Yuki Sekiguchi, Yumi Ozaki, Noriko Ninomiya, Yoshikazu Sato, Satoru Takahashi","doi":"10.5980/jpnjurol.112.173","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.173","url":null,"abstract":"<p><p>(Purpose) To translate the Vulvovaginal Symptoms Questionnaire (VSQ) into Japanese and evaluate the linguistic validation of the translated VSQ. (Methods) The translation and evaluation of the VSQ were performed through 3 steps: forward translation based on 2 urologists and discussed by another 3 urologists; the community review process, which consisted of one-on-one cognitive interviews with 20 patients by professional interviewers; backward translation by a native English speaker, which was discussed with the original author of the VSQ. (Results) The original author of the VSQ generally approved our translation. (Conclusion) The Japanese version of the VSQ was translated in a linguistically valid manner. It is equivalent to the original English questionnaire. It may provide a tool to assess sexual function for Japanese women with genitourinary syndrome of menopause.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 4","pages":"173-178"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40374540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[AN ABSCESS OF CORPUS SPONGIOSUM CAUSED BY CANDIDURIA: A CASE REPORT].","authors":"Suzuna Sakai, Kosuke Takehara, Junichi Watanabe","doi":"10.5980/jpnjurol.112.215","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.215","url":null,"abstract":"An 88-year-old man was treated with a urethral bougie after balloon dilation for urethral stricture in 2019. In December 2020, the patient was referred to our hospital with a fever and voiding disturbance. The patient was diagnosed with a urinary tract infection at the time of admission and was treated with an antibacterial agent. Candia glabrata was detected in both the blood and urine cultures obtained on admission. However, antifungal therapy was not administered because the blood culture was negative on reexamination. Sixteen days after admission, magnetic resonance imaging revealed an abscess in the corpus spongiosum. Cystostomy and abscess drainage were performed because the corpus spongiosum abscess was worsening. Candia glabrata was detected in the abscess; therefore, we treated the patient with antifungal therapy. After 14 days of antifungal agent treatment, the corpus spongiosum abscess disappeared. An abscess of the corpus spongiosum caused by candiduria is exceedingly rare; this is the first reported case in Japan.","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 4","pages":"215-219"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40375503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[PELVIC ORGAN PROLAPSE AND INGUINAL HERNIA AGGRAVATED BY OVARIAN FIBROTHECOMA WITH ASCITES].","authors":"Aika Matsuyama, Kumiko Kato, Shoji Suzuki, Yuki Nishiko, Hiroki Sai, Akinobu Ishiyama, Takashi Kato, Satoshi Inoue, Hiroki Hirabayashi, Ryohei Hattori","doi":"10.5980/jpnjurol.112.137","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.137","url":null,"abstract":"<p><p>We present a case of pelvic organ prolapse and inguinal hernia worsened by a benign ovarian tumor with ascites. A 61-year-old woman was referred to us complaining of feeling of something protruding from her vagina. She was diagnosed with Stage III cystocele. Behavioral therapy was administered as she had only slight subjective symptoms. She visited us eight months later due to a rapid aggravation of cystocele and voiding difficulty. She subsequently developed acute abdominal pain caused by incarcerated inguinal hernia. Abdominal ultrasound, MRI and CT showed a 10.6×9.0 cm pelvic mass with ascites. As an ovarian cancer with peritoneal dissemination was suspected, she immediately underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and colposuspension. Pathological diagnosis was fibrothecoma, a benign ovarian tumor. Postoperative course was uneventful, and ascites quickly disappeared in a manner similar to Meigs syndrome. Although no procedure was done to manage inguinal hernia, it was unproblematic for 18 months, after that it worsened, necessitating hernial repair. She had no recurrence of prolapse or ascites.Increased intra-abdominal pressure due to abdominal mass or ascites can worsen prolapse and hernial diseases such as inguinal, umbilical, and abdominal hernia. In this case, ovarian fibrothecoma with ascites seemed to be responsible for worsening of the prolapse and inguinal hernia. To conclude, it is important to consider background diseases when examining patients with prolapse and coexisting hernial diseases.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 3","pages":"137-140"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40539557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[ASSOCIATION OF BREATH HYDROGEN CONCENTRATION WITH ORAL INTAKE AND URINARY DISEASES].","authors":"Kimio Sugaya, Saori Nishijima, Katsumi Kadekawa, Katsuhiro Ashitomi, Katsuhiko Noguchi, Seiji Matsumoto, Hideyuki Yamamoto","doi":"10.5980/jpnjurol.112.11","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.11","url":null,"abstract":"<p><p>(Purpose) Ingestion of hydrogen is said to prevent oxidation in the body, but hydrogen is produced by intestinal bacterial flora and excreted in the exhaled breath. We investigated how breath hydrogen concentrations change with the diurnal cycle and under various conditions, including after consuming food or drink, and in people with urological disease. (Subjects and methods) Participants were healthy volunteers (40 men, 45 women; 30-83 years old) and urological outpatients (40 men with benign prostatic hyperplasia, 30 women with overactive bladder; 60 years or older). Breath hydrogen levels were measured before and after eating and drinking in three volunteers, and its diurnal variation was examined in one. The relationship between breath hydrogen and age or urological disease status was also analyzed by gender. Additional measurements were taken in the person with the highest breath hydrogen concentration and the person with the lowest; in these two people, breath hydrogen was measured at the same time for 10 or more days to determine the fluctuation range. (Results) Breath hydrogen concentration increased temporarily after ingestion of tap water, hydrogen water or food. It also increased with food intake and in cases of flatulence with intestinal gas accumulation, but decreased after defecation. In the person with the highest breath hydrogen, concentrations were 11.2-188.6 ppm, whereas in the person with the lowest, they were 0.4-2.3 ppm. Breath hydrogen increased significantly with age in healthy female volunteers. There was no association between breath hydrogen and benign prostatic hyperplasia, overactive bladder or constipation. (Conclusion) Breath hydrogen concentration increases with eating, drinking and aging, and is not associated with benign prostatic hyperplasia, overactive bladder or constipation. Breath hydrogen concentration varies widely between individuals, which may be due to differences in intestinal flora.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 1","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39834793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A CASE OF PRIMARY ADRENAL LYMPHOMA SUSPECTED AS ADRENAL METASTATIC TUMOR FROM GASTROINTESTINAL STROMAL TUMOR].","authors":"Tomohiro Kanaki, Atsunari Kawashima, Shinichiro Fukuhara, Kazutoshi Fujita, Motohide Uemura, Hiroshi Kiuchi, Ryoichi Imamura, Norio Nonomura","doi":"10.5980/jpnjurol.112.29","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.29","url":null,"abstract":"<p><p>We present a case of 75 year's old man for whom small bowel resection was performed for a small intestinal tumor diagnosed as a gastrointestinal stromal tumor (GIST) with KIT exon 11 mutation and intermediate Miettinen risk. Computed tomography (CT) 18 months after surgery showed a right adrenal mass measuring 20 mm in size. Imatinib therapy couldn't show the tumor shrinkage, and the adrenal mass increased up to 37 mm in size 3 months later. He was referred to our department for further examination and treatment. We diagnosed this adrenal tumor as imatinib resistant GIST or adrenal primary malignancy and performed retroperitoneal laparoscopic right adrenalectomy. The pathological diagnosis was diffuse large B-cell lymphoma (DLBCL) not GIST and PET-CT revealed systemic metastasis of DLBCL one month later after surgery. Six courses of R-CHOP therapy achieved a complete response.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39834796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[ANALYSIS OF THE ASSOCIATION BETWEEN IMMUNE-RELATED ADVERSE EVENTS AND THE EFFICACY OF PEMBROLIZUMAB IN PATIENTS WITH METASTATIC UROTHELIAL CARCINOMA].","authors":"Akihito Hashizume, Ryo Yamashita, Hideo Shinsaka, Masafumi Nakamura, Masato Matsuzaki, Masashi Niwakawa","doi":"10.5980/jpnjurol.112.179","DOIUrl":"https://doi.org/10.5980/jpnjurol.112.179","url":null,"abstract":"<p><p>(Objectives) We evaluated the association between immune-related adverse events (irAEs) and the efficacy of pembrolizumab therapy in patients with metastatic urothelial carcinoma. (Methods) Data of 42 patients with metastatic urothelial carcinoma treated with pembrolizumab between May 2018 and February 2020 were retrospectively analyzed to determine the association between irAEs and objective response rate (ORR), progression-free survival (PFS), and overall survival (OS). (Results) IrAEs were observed in 19 patients (45.2%). Objective response was observed in 15 patients (35.7%). Thirteen (68.4%) of 19 patients who experienced irAEs showed an objective response, whereas two (8.70%) of 23 patients who did not experience irAEs (odds ratio: 15.0, 95% confidence interval [CI]: 1.70-738, P=0.006). PFS and OS in the irAE group were longer than those in the non-irAE group (PFS: hazard ratio: 0.24, 95% CI: 0.11-0.54, P<0.001; OS: hazard ratio: 0.11, 95% CI: 0.03-0.37, P<0.001). (Conclusions) During pembrolizumab treatment, the occurrence of irAEs was significantly associated with higher response and survival prolongation in patients with metastatic urothelial carcinoma.</p>","PeriodicalId":38850,"journal":{"name":"Japanese Journal of Urology","volume":"112 4","pages":"179-184"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40374541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}