[原发性肾上腺淋巴瘤1例,怀疑为胃肠道间质瘤转移性肾上腺瘤]。

Q4 Medicine
Tomohiro Kanaki, Atsunari Kawashima, Shinichiro Fukuhara, Kazutoshi Fujita, Motohide Uemura, Hiroshi Kiuchi, Ryoichi Imamura, Norio Nonomura
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引用次数: 0

摘要

我们报告了一例75岁的男性,他的小肠肿瘤被诊断为胃肠道间质瘤(GIST), KIT外显子11突变和中等Miettinen风险。术后18个月的计算机断层扫描显示右侧肾上腺有20毫米大小的肿块。伊马替尼治疗未见肿瘤缩小,3个月后肾上腺肿物增大至37 mm。他被转到我科作进一步检查和治疗。我们将此肾上腺肿瘤诊断为伊马替尼抵抗性GIST或肾上腺原发性恶性肿瘤,并行腹膜后腹腔镜右肾上腺切除术。病理诊断为弥漫性大b细胞淋巴瘤(DLBCL),非GIST,术后1个月PET-CT显示DLBCL全身转移。6个疗程的R-CHOP治疗获得完全缓解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[A CASE OF PRIMARY ADRENAL LYMPHOMA SUSPECTED AS ADRENAL METASTATIC TUMOR FROM GASTROINTESTINAL STROMAL TUMOR].

We present a case of 75 year's old man for whom small bowel resection was performed for a small intestinal tumor diagnosed as a gastrointestinal stromal tumor (GIST) with KIT exon 11 mutation and intermediate Miettinen risk. Computed tomography (CT) 18 months after surgery showed a right adrenal mass measuring 20 mm in size. Imatinib therapy couldn't show the tumor shrinkage, and the adrenal mass increased up to 37 mm in size 3 months later. He was referred to our department for further examination and treatment. We diagnosed this adrenal tumor as imatinib resistant GIST or adrenal primary malignancy and performed retroperitoneal laparoscopic right adrenalectomy. The pathological diagnosis was diffuse large B-cell lymphoma (DLBCL) not GIST and PET-CT revealed systemic metastasis of DLBCL one month later after surgery. Six courses of R-CHOP therapy achieved a complete response.

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来源期刊
Japanese Journal of Urology
Japanese Journal of Urology Medicine-Urology
CiteScore
0.20
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