Tunisie Medicale最新文献_第3页

Prevalence, incidence, and residual risk of HIV among blood donors in Sfax (Tunisia). 斯法克斯（突尼斯）献血者中艾滋病毒的流行、发病率和剩余风险。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6075

Taicir Rekik, Latifa Derbel, Nour Louati, Mariem Ben Hmida, Héla Menif, Ikram Ben Amor

{"title":"Prevalence, incidence, and residual risk of HIV among blood donors in Sfax (Tunisia).","authors":"Taicir Rekik, Latifa Derbel, Nour Louati, Mariem Ben Hmida, Héla Menif, Ikram Ben Amor","doi":"10.62438/tunismed.v104i04.6075","DOIUrl":"https://doi.org/10.62438/tunismed.v104i04.6075","url":null,"abstract":"Background and aim: Blood transfusion is not without risk, particularly the infectious risk related to the Human Immunodeficiency Virus (HIV). The objective of our study is to report the evolution of HIV indicators in blood donors (BDs) at the regional blood transfusion center of Sfax (Tunisia).Methods: This was a retrospective descriptive study including both replacement and voluntary BDs collected from mobile and fixed donation units over a 10-year period (January 2014-December 2023). Combined screening for HIV antigens and antibodies was carried out by ELISA, with confirmation of positive results by Western blot. Prevalence and seroconversions according to age group, gender, and donation type were analyzed using the Hématos II G3.8 software by GPI. Incidence and residual risk were calculated using the Schreiber mathematical model.Results: Forty-seven BDs were confirmed to be HIV-positive, with a male predominance (87.23%). The overall HIV prevalence was 0.16‰, with a peak of 0.4‰. During the study period, 21 seroconversions were recorded. The incidence was 9.38 per 100,000 person-years, and increased from 33.28 per 100,000 person-years in 2014-2015 to 97.22 per 100,000 person-years in 2022-2023. The residual risk was 0.46 per 100,000 donations.Conclusion: Prevention is the key pillar in reducing the residual risk of HIV transmission through transfusions. It is based on improved HIV awareness in the general population and rigorous BDs selection.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"535-540"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time to Management of Colorectal Cancer: Audit of the Gastroenterology Department at Mongi Slim Hospital. 大肠癌的时间管理：蒙济医院消化内科审计。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6598

Abdelwahab Nakhli, Cyrine Ben Mehrez, Oussama Ghachem, Amal Jerbi, Zeineb Benzarti, Yosr El Mouldi, Bochra Bouchabou, Rym Ennaifer

{"title":"Time to Management of Colorectal Cancer: Audit of the Gastroenterology Department at Mongi Slim Hospital.","authors":"Abdelwahab Nakhli, Cyrine Ben Mehrez, Oussama Ghachem, Amal Jerbi, Zeineb Benzarti, Yosr El Mouldi, Bochra Bouchabou, Rym Ennaifer","doi":"10.62438/tunismed.v104i04.6598","DOIUrl":"https://doi.org/10.62438/tunismed.v104i04.6598","url":null,"abstract":"Introduction: Colorectal cancer (CRC) is a major public health issue in Tunisia. This study aimed to evaluate the time to management of CRC at Mongi Slim Hospital and identify factors associated with a longer delay.Methods: Retrospective study including adult patients with histologically confirmed CRC treated with curative intent between April 2013 and December 2019.Results: Fifty-four patients were included (mean age 63 years, male-to-female ratio 1.16). The mean diagnosis-to-treatment interval was 44 days (median 33). Delay (>30 days) occurred in 57% of patients. Predictors of delay were staging in the public sector and outpatient management. Outpatient management refers to patients followed via ambulatory medical consultations where the diagnostic workup (notably CT scans and biopsies) was performed externally.Conclusion: More than half of the patients experienced delayed management. Structural and organizational measures are required to improve timelines and CRC prognosis.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"547-550"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hormonal profiles and semen parameters in men with primary infertility: Evidence from eastern Libya. 原发性不孕症男性的激素谱和精液参数：来自利比亚东部的证据。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6627

Mohammed Abugilah, Majduldeen Alhlafi, Ahmed Milad

{"title":"Hormonal profiles and semen parameters in men with primary infertility: Evidence from eastern Libya.","authors":"Mohammed Abugilah, Majduldeen Alhlafi, Ahmed Milad","doi":"10.62438/tunismed.v104i04.6627","DOIUrl":"10.62438/tunismed.v104i04.6627","url":null,"abstract":"Introduction: Male infertility remains a significant global health concern, with hormonal evaluation playing a critical role in understanding spermatogenic dysfunction. While follicle-stimulating hormone (FSH) is widely recognized as a marker of testicular function, the diagnostic value of other hormones such as luteinizing hormone (LH), testosterone, and prolactin remains debated, particularly in context that are specific to a given region.Objective: To assess the relationship between serum gonadotropins (FSH, LH), total testosterone, and prolactin and semen quality parameters in Libyan males presenting with primary infertility.Methods: This cross-sectional study included 138 males attending a fertility center in East Libya. Semen analysis was performed according to WHO 2010 guidelines. Morning fasting serum levels of FSH, LH, testosterone, and prolactin were measured using standardized immunoassays. Spearman's correlation and multivariate linear regression were used to evaluate associations between hormonal profiles and semen parameters.Results: FSH was significantly associated with sperm concentration (ρ = -0.324, p < .05; β = -1.107, p = .010). LH showed a weak inverse correlation(ρ = -0.175) but lacked predictive value. Testosterone and prolactin were not significantly associated with semen volume, motility, or morphology. Strong internal correlations were observed between progressive motility and morphology (ρ = .569).Conclusion: Elevated FSH levels are a reliable indicator of impaired spermatogenesis in Libyan males with primary infertility. The limited associations of LH, testosterone, and prolactin with semen parameters suggest that FSH should be prioritized in hormonal evaluation. These findings support targeted endocrine testing and underscore the need for region-specific reference ranges and expanded hormonal profiling in future research.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"525-530"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Twelve-month retention of technical skills in basic life support following simulation-based training among paramedical staff]. [对辅助医务人员进行为期12个月的模拟培训后基本生命支持技术技能的保留]。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6465

Héla Ben Turkia, Hanene Ghazali, Youssef Ebn Ebrahim, Syrine Keskes, Raja Fadhel, Sami Souissi

{"title":"[Twelve-month retention of technical skills in basic life support following simulation-based training among paramedical staff].","authors":"Héla Ben Turkia, Hanene Ghazali, Youssef Ebn Ebrahim, Syrine Keskes, Raja Fadhel, Sami Souissi","doi":"10.62438/tunismed.v104i04.6465","DOIUrl":"https://doi.org/10.62438/tunismed.v104i04.6465","url":null,"abstract":"Introduction: Simulation-based training is recognized as an effective educational strategy for acquiring clinical competencies, particularly among paramedical personnel. However, long-term retention of these skills remains insufficiently studied. The aim was to assess the 12-month retention of technical skills in basic life support (BLS) following initial simulation-based training among paramedical staff.Methods: We conducted a 12-month, single-center prospective study including 17 paramedicals working in an emergency department. Participants underwent a theoretical pre-test and an initial practical assessment of BLS skills (chest compressions and bag-valve-mask ventilation), followed by procedural simulation training. Knowledge and technical skills were evaluated immediately post-training (T1) and at 12 months (T2), using a standardized checklist scored out of 15.Results: inclusion of 36 participants, 17 achieved all steps. Mean theoretical scores improved from 7.24±2.15 at baseline to 11.75±5.55 immediately after training (p=0.013), reaching 12.28±3.77 at 12 months. Practical skill scores significantly increased from 4.17±1.34 at baseline to 12.52±1.34 at T1 (p<0.001), with a mean score of 11.14±1.95 at T2, indicating substantial skill retention.Conclusion: Our findings demonstrate sustained retention of both theoretical knowledge and technical skills in BLS at 12 months following simulation-based training among paramedical personnel. These results support the long-term educational value of simulation in enhancing emergency response capabilities within this population. However, a slight decline in performance at 12 months highlights the need for refresher training sessions.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"508-513"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Consultation Time and Quality of Care in Morocco: Lessons for Developing Countries]. [摩洛哥的咨询时间和护理质量：发展中国家的经验教训]。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6386

Abdellatif Moustatraf, Abdelati Zouine, Fatima Touhami

{"title":"[Consultation Time and Quality of Care in Morocco: Lessons for Developing Countries].","authors":"Abdellatif Moustatraf, Abdelati Zouine, Fatima Touhami","doi":"10.62438/tunismed.v104i04.6386","DOIUrl":"10.62438/tunismed.v104i04.6386","url":null,"abstract":"Introduction: In middle-income countries, the duration of medical consultations is a key determinant of care quality, particularly given the limited health literacy of part of the population. This study analyzes its impact in Morocco by exploring the perceptions of beneficiaries of Compulsory Health Insurance (AMO).Methods: A mixed-methods design combined a literature review with a survey of 240 AMO beneficiaries. Data were collected through a questionnaire focusing on listening, clarity of explanations, consultation length, and patient expectations.Results: Most patients reported feeling listened to and considered the explanations clear. However, a significant proportion expressed unmet needs, especially regarding consultation time and medical jargon. The average consultation duration (15-20 minutes) was considered sufficient by two-thirds of patients, while one-third desired more time. Overall satisfaction reached 80%.Conclusions: Consultation length is a major lever for enhancing doctor-patient communication and perceived quality of care. In resource-limited settings, interventions such as simplifying medical language, training healthcare providers in communication skills, and optimizing consultation time management are crucial. These findings, while grounded in the Moroccan context, provide valuable lessons for middle-income countries facing similar challenges.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"568-573"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Impact of an educational video on learning toxoplasmosis serodiagnosis in pregnant women]. 【教育视频对孕妇学习弓形虫病血清诊断的影响】。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6613

Latifa Mtibaa, Nessrine Souayeh, Fatma Said, Rim Charfi, Boutheina Jemli

{"title":"[Impact of an educational video on learning toxoplasmosis serodiagnosis in pregnant women].","authors":"Latifa Mtibaa, Nessrine Souayeh, Fatma Said, Rim Charfi, Boutheina Jemli","doi":"10.62438/tunismed.v104i04.6613","DOIUrl":"10.62438/tunismed.v104i04.6613","url":null,"abstract":"Introduction: Toxoplasmosis is a major public health concern, especially in pregnant women, due to the risk of maternal-fetal transmission. Serodiagnosis, although essential, remains challenging for medical biology residents.Objective: To evaluate the impact of an educational video on knowledge acquisition and learner perception regarding the serodiagnosis of toxoplasmosis in pregnant women.Methods: An observational study was conducted at the Faculty of Medicine of Tunis (May-September 2025), including medical biology residents. Participants completed a pre-test, watched an educational video, and then completed a post-test and a qualitative evaluation. Pre- and post-test means were compared using a paired Student's t-test, and the correlation between knowledge gain and satisfaction was assessed with Pearson's coefficient.Results: Sixty-four residents participated (mean age: 28.5 years; sex ratio = 0.08). Mean scores increased from 12.28 ± 4.0 (pre-test) to 15.41 ± 3.5 (post-test) (p < 0.001), reflecting a significant knowledge gain, with 52% scoring ≥16/20 post-intervention. Overall satisfaction was high: 91% found the video clear and relevant, and 97% would recommend it to colleagues. The correlation between score gain and satisfaction was weak and not significant (r = 0.16; p = 0.26).Conclusion: The educational video is an effective and highly appreciated tool for teaching the serodiagnosis of toxoplasmosis, facilitating the understanding and interpretation of complex serological profiles.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"514-517"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluoroquinolones versus doxycycline in the treatment of rickettsial infection: A Tunisian multicenter prospective study. 氟喹诺酮类药物与多西环素治疗立克次体感染：突尼斯多中心前瞻性研究

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6328

Nadia Ben Lasfar, Manel Ben Selma, Mariem Ben Ticha, Mounir Ben Jemaa, Lamia Ammeri, Maha Abid, Amel Letaief, Wissem Hachfi

{"title":"Fluoroquinolones versus doxycycline in the treatment of rickettsial infection: A Tunisian multicenter prospective study.","authors":"Nadia Ben Lasfar, Manel Ben Selma, Mariem Ben Ticha, Mounir Ben Jemaa, Lamia Ammeri, Maha Abid, Amel Letaief, Wissem Hachfi","doi":"10.62438/tunismed.v104i04.6328","DOIUrl":"10.62438/tunismed.v104i04.6328","url":null,"abstract":"Introduction: Doxycycline is considered as the standard treatment of rickettsiosis.Fluoroquinolones used as an alternative therapy, until recent studies have shown that Fluoroquinolones are associated with a deleterious outcome Objectives : To compare therapeutic efficacy and safety of fluoroquinolones and doxycycline in the treatment of Rickettsiosis Methods: we conducted an open-label randomized controlled multicenter study. This study aim to compare the efficacy and safety of oral ciprofloxacin (1000 mg/day) or ofloxacin (400mp/day) in 2 doses with those of oral doxycycline (200mg/day) once daily for 3 to 10 days, according to the severity of illness, in the treatment of Rickettsioses, We included patients more than 15 year-old who presented the characteristic clinical triad (eschar + rash + fever) and/or microbiological confirmation (positive serology and/or positive qPCR).Results: Among 112 enrolled patients, 82 retained. Thirty-four patients received fluoroquinolones and 48 received doxycycline. Patients in both groups were comparable with respect to age. Two severe cases were noted with fluoroquinolones (meningitis = one, encephalitis= 1) and three with doxycycline (myocarditis=one, severe sepsis = l and encephalitis =1) .|The defervescence period was 2.6 + 1.04 days in the doxycycline group and2.31.09 days in the fluoroquinolones group (p20.05). All patients recovered. One patient treated by doxycycline had a digital necrosis, generating amputation.Conclusions: Both fluoroquinolones and doxycycline were effective for treating patients with rickettsia infections. Even that doxycycline remains the standard of treatment, with the advantage of a single daily dose; fluoroquinolones are an interesting alternative with no deleterious outcome.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"531-534"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Inherited epidermolysis bullosa in Dakar : Descriptive cross-sectional study of 36 cases]. 【达喀尔地区遗传性大疱性表皮松解症：36例描述性横断面研究】。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6176

Mame Tene Ndiaye Diop, Khadim Diop, Birame Seck, Khadija Ba, Fatou Diassé Fall, Babacar Niang, Moussa Diallo, Ousmane Ndiaye, Maodo Ndiaye, Fatimata Ly, Suzanne Oumou Niang

{"title":"[Inherited epidermolysis bullosa in Dakar : Descriptive cross-sectional study of 36 cases].","authors":"Mame Tene Ndiaye Diop, Khadim Diop, Birame Seck, Khadija Ba, Fatou Diassé Fall, Babacar Niang, Moussa Diallo, Ousmane Ndiaye, Maodo Ndiaye, Fatimata Ly, Suzanne Oumou Niang","doi":"10.62438/tunismed.v104i04.6176","DOIUrl":"https://doi.org/10.62438/tunismed.v104i04.6176","url":null,"abstract":"Introduction: The aim of this study was to determine the frequency, clinical forms and complications of Inherited epidermolysis bullosa in Dakar.Methodology: we conducted a descriptive cross-sectional study with data collection from medical records of patients followed up for Inherited epidermolysis bullosa in the dermatology department of the Albert Royer Children's Hospital over an 11-year period.Results: 36 patients were registered, representing a hospital frequency of 0.16% and a sex ratio of 0.6. Clinical forms were: dystrophic in 44%, simple in 33%, junctional in 17%, associated with congenital cutaneous aplasia in 6% (Bart's syndrome), Kindler's syndrome in 6%. Complications occurred in 39% of cases, including infections in 28%, hemodynamic disorders in 17% and digestive complications in 11%. Death was recorded in 11% as a result of infectious and anemia.Conclusion: We report a series of 36 cases of inherited epidermolysis bullosa, representing a hospital frequency of 0.16%. The most frequent clinical form is dystrophic. Complications are mainly infectious and hemodynamic. We emphasize the importance of follow-up in these patients, given the risk of skin cancer associated with the long-term prognosis of scars in dystrophic forms.","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"104 4","pages":"563-567"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Massive Bronchial Artery Hypertrophy Diagnosed by Aortography in Recurrent Hemoptysis. 反复咯血的主动脉造影诊断大量支气管动脉肥大。

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6623

Bayram Altuntaş, Hacer Bal Hacer Bal

引用次数: 0

The generative artificial intelligence takeover in peer review: Progress or peril? 生成式人工智能在同行评议中的接管：进步还是危险？

Tunisie Medicale Pub Date : 2026-04-30 DOI: 10.62438/tunismed.v104i04.6666

Mohamed Ali Chaouch, Ismail Dergaa, Karim Chamari, Denis Sablot, Helmi Ben Saad

引用次数: 0