Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica最新文献

Revisión sistemática de la metodología de tratamiento del síndrome de fatiga crónica 慢性疲劳综合征治疗方法的系统回顾

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-07-01 DOI: 10.1016/j.sedene.2024.04.002

Sergio López Barbeta , Manuela Carrión Martínez , Alejandro Lendínez Mesa , Alberto Diliz Vieira , Carlos Díaz-Rodríguez

{"title":"Revisión sistemática de la metodología de tratamiento del síndrome de fatiga crónica","authors":"Sergio López Barbeta , Manuela Carrión Martínez , Alejandro Lendínez Mesa , Alberto Diliz Vieira , Carlos Díaz-Rodríguez","doi":"10.1016/j.sedene.2024.04.002","DOIUrl":"10.1016/j.sedene.2024.04.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic fatigue syndrome (CFS) is a highly prevalent pathology that has not been clearly defined. Currently, there is no universally accepted treatment protocol, and the diagnostic markers, etiology, and specific pathophysiology for developing effective non-pharmacological treatments remain unknown.</div></div><div><h3>Objective</h3><div>To determine the currently established rehabilitation treatment methodologies for CFS. In addition, to establish an analysis of the efficacy of the treatment plans studied and to determine advances on the etiology of CFS.</div></div><div><h3>Method</h3><div>A systematic review of randomized clinical trials (RCTs) published since 2011 was conducted. Studies evaluating non-pharmacological interventions for adult CFS patients were included, differentiating them according to chosen diagnostic criteria and variable measurement. The treatment hypothesis of the selected interventions was also taken into account.</div></div><div><h3>Results</h3><div>17 RCTs were included, 6 of which based their performance protocol on a self-management booklet and 11 of which did so through face-to-face involvement of a therapist and active therapy. The results of these studies were assessed primarily by patient-reported outcomes, and 5 of these studies reported on objective outcome measures.</div></div><div><h3>Conclusion</h3><div>There is no significant evidence on the efficacy of non-pharmacological interventions in CFS patients. In addition, the lack of consensus on diagnostic criteria makes it difficult to compare studies and to develop a standardised treatment plan. Advances in the aetiology and pathophysiology of CFS point to the need for a broader therapeutic approach.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"62 ","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141274401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Síndrome del acento extranjero: descripción de un caso clínico 外国口音综合症：临床病例描述

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-07-01 DOI: 10.1016/j.sedene.2024.03.003

Ana Teresa Domínguez Martín , Noemi Martin Ramos , Sara Huerta González , Armando Diez Miranda , Catalina Cano Amador

{"title":"Síndrome del acento extranjero: descripción de un caso clínico","authors":"Ana Teresa Domínguez Martín , Noemi Martin Ramos , Sara Huerta González , Armando Diez Miranda , Catalina Cano Amador","doi":"10.1016/j.sedene.2024.03.003","DOIUrl":"10.1016/j.sedene.2024.03.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Foreign Accent Syndrome (FAS) is an acquired speech disorder due to a lesion of the central nervous system, characterized by the appearance of a foreign accent when speaking the native language. The objective is to describe a case of SAE as a form of presentation of a stroke.</div></div><div><h3>Development</h3><div>Male, 72 years old, Spanish, with ischemic heart disease, dyslipidemia, COPD. Autonomous for Activities of Daily Living. Admitted for chest pain on slight exertion. Presents difficulty in responding and obeying orders, feels that the accent and speed of speech are different. His relatives say that he speaks like the English, but in Spanish.</div><div>In neurological examination conscious, oriented, obeys orders, no dysarthria. Language is clear, fluent and intelligible, with alteration of intonation and rhythm. Mild right facial paresis.</div></div><div><h3>Results</h3><div>A care plan was developed based on Gordon's functional patterns, with NANDA diagnoses, interventions (NIC) and expected outcomes (NOC). Due to the rarity of the case it is justified to establish an individualized care plan, obtaining 7 nursing diagnoses and 12 nursing interventions with their respective NOC.</div><div>The Clinical Judgment was of ischemic stroke of cardioembolic origin. The evolution was favorable, after 3 months she recovered her normal accent and did not report any speech alteration or identity problems.</div></div><div><h3>Conclusion</h3><div>SAE is an infrequent syndrome, which can generate identity conflicts if it does not subside.</div><div>We consider it necessary to be aware of this syndrome so that it can be recognized early, and to be able to offer a correct nursing approach that guarantees quality care and psychological support.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"62 ","pages":"Article 100165"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estudio piloto: terapia transdisciplinar en el medio acuático en niños con discapacidad intelectual 试点研究：对智障儿童进行跨学科水生治疗

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-07-01 DOI: 10.1016/j.sedene.2024.500169

Rocío Blanco Barrero , Sara Rodriguez Carrión , Susana Álvarez Hernando , Lorena Martín Berbel , Ana Navarro Meléndez , Alejandro Lendinez Mesa , Ana Sofía Fernandes Ribeiro , María Jesús Martínez Beltrán

{"title":"Estudio piloto: terapia transdisciplinar en el medio acuático en niños con discapacidad intelectual","authors":"Rocío Blanco Barrero , Sara Rodriguez Carrión , Susana Álvarez Hernando , Lorena Martín Berbel , Ana Navarro Meléndez , Alejandro Lendinez Mesa , Ana Sofía Fernandes Ribeiro , María Jesús Martínez Beltrán","doi":"10.1016/j.sedene.2024.500169","DOIUrl":"10.1016/j.sedene.2024.500169","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze whether transdisciplinary therapy in the aquatic environment for children with intellectual disabilities promotes skills and mental adjustment in this setting, advances in different areas of their lives, and independence in activities of daily living.</div></div><div><h3>Method</h3><div>Quasi-experimental pilot study carried out with children with intellectual disabilities from the Special Education School of the Hospital Fundación Instituto San José, who integrate transdisciplinary therapy in the aquatic environment with the Poseidon Program in their school environment between September 2018 and June 2019.</div><div>Variables have been collected such as aquatic skills, motor, personal/social, cognitive, communicative, adaptive and essential functional skills of daily living, as measured with the WeeFIM scale, WOTA 1 and the Battelle Developmental Inventory.</div></div><div><h3>Results</h3><div>Data from 5 children aged between 6±2 years and a degree of disability of 46±15 years have been included. Statistically significant differences were found in the personal/social area (p=0,042) with a 3-point difference between pre/post-intervention measurements, as well as in the global area (p=0,042) with a 9-point difference, measured through the Battelle inventory.</div><div>Autism, developmental disorder, and epilepsy variables do not show a statistically significant association.</div></div><div><h3>Conclusions</h3><div>The transdisciplinary methodology carried out through the Poseidon program produces statistically significant improvements in different areas of life and independence in the activities of daily living of children with intellectual disabilities.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"62 ","pages":"Article 500169"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activación de áreas cerebrales al comer chocolate y aumento de crisis epilépticas focales 吃巧克力时大脑区域的激活和局部癫痫发作的增加

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-07-01 DOI: 10.1016/j.sedene.2024.500167

María Palanca Cámara , Sònia Pineda Hernández

{"title":"Activación de áreas cerebrales al comer chocolate y aumento de crisis epilépticas focales","authors":"María Palanca Cámara , Sònia Pineda Hernández","doi":"10.1016/j.sedene.2024.500167","DOIUrl":"10.1016/j.sedene.2024.500167","url":null,"abstract":"<div><h3>Introduction</h3><div>Epilepsy is a neurological disease characterized by the onset of epileptic seizures, due to an abnormal electrical discharge of the brain; so that it affects a specific region (focal epilepsy), or the whole brain (generalized epilepsy). Epilepsy has always been stigmatized, largely due to lack of knowledge about the disease. One of these myths has been the relationship between chocolate and its power to promote the onset of epileptic seizures.</div></div><div><h3>Objective</h3><div>Find scientific evidence on brain activation by chocolate and its capacity for epileptogénesis.</div></div><div><h3>Methodology</h3><div>A literature search was performed on PubMed, Google Scholar and Trip database. Subsequently, a critical reading of the selected articles was performed obtaining a total of 10 relevant articles.</div></div><div><h3>Conclusions</h3><div>In animal studies, a relationship was found between chocolate consumption and hippocampal seizures. No studies have been found in humans in this line of research, however, in studies in healthy people it has been observed that chocolate activates the mesial temporal and frontal areas, with epilepsy originating in the temporal and frontal lobes, and more specifically the mesial structures, the most prevalent in humans. However, studies in people with epilepsy are necessary to establish the relationship between chocolate and ictogenesis.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"62 ","pages":"Article 500167"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validez convergente de la escala Tinetti en pacientes con ictus en fase subaguda 亚急性中风患者的Tinetti量表收敛有效性

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-07-01 DOI: 10.1016/j.sedene.2024.500168

Adrián Arranz–Escudero , Patricia Martín–Casas , Ester Carpio–Calatayud , Ibai López–de–Uralde–Villanueva

{"title":"Validez convergente de la escala Tinetti en pacientes con ictus en fase subaguda","authors":"Adrián Arranz–Escudero , Patricia Martín–Casas , Ester Carpio–Calatayud , Ibai López–de–Uralde–Villanueva","doi":"10.1016/j.sedene.2024.500168","DOIUrl":"10.1016/j.sedene.2024.500168","url":null,"abstract":"<div><h3>Introduction</h3><div>Clinical scales to assess balance and gait in stroke patients such as the Trunk Impairment Scale (TIS), Postural Assessment Scale for Stroke (PASS) and Functional Ambulatory Categories (FAC) have been extensively studied. However, the Tinetti scale has not yet been validated in the Spanish neurological population.</div></div><div><h3>Objectives</h3><div>To analyze the convergent validity of Tinetti scale in post-stroke patients in the subacute phase.</div></div><div><h3>Method</h3><div>A cross-sectional study was performed in a neurological rehabilitation clinic including patients who had started rehabilitation within 2 months after the stroke and were hemodynamically stable, excluding patients with psychiatric disorders. Spearman correlation coefficients were calculated to analyze the convergent validity of the Tinetti scale with the clinical assessments TIS, PASS and FAC measured at the beginning of rehabilitation.</div></div><div><h3>Results</h3><div>A total of 63 participants were analyzed. The average age was 63.87±12,93 years and men (58.73%), ischemic stroke (69.84%), stroke located in the middle cerebral artery (44.44%) and high grade of affectation patients predominated. The convergent validity of the Tinetti scale in patients with stroke in the subacute phase at the initial assessment was significantly high with TIS (0.805) and very high with PASS (0.936) and FAC (0.927) (p<0.05).</div></div><div><h3>Conclusion</h3><div>Tinetti scale is a valid instrument to assess balance and gait in subacute phase stroke patients and has an excellent convergent validity with other balance and gait clinical scales. Further investigation should be undertaken to analyze other psychometric properties.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"62 ","pages":"Article 500168"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

La ELA vivida, la enfermería sentida: palabras de un testigo agradecido 活着的ELA，感受到的关怀：一位感激的目击者的话

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-07-01 DOI: 10.1016/j.sedene.2025.500193

Juan Carlos Unzué

引用次数: 0

Evaluación de la calidad y manejo de la cefalea en un paciente ingresado en el área de Neurociencia. Estudio CALMA 评估神经科学部门收治的头痛患者的治疗质量和管理。CALMA 研究

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-01-01 DOI: 10.1016/j.sedene.2024.01.001

Eulalia Gine-Cipres , Marta Torres Ferrus , Victor J. Gallardo , Alicia Alpuente Ruiz , Edoardo Caronna , Patricia Pozo-Rosich

{"title":"Evaluación de la calidad y manejo de la cefalea en un paciente ingresado en el área de Neurociencia. Estudio CALMA","authors":"Eulalia Gine-Cipres , Marta Torres Ferrus , Victor J. Gallardo , Alicia Alpuente Ruiz , Edoardo Caronna , Patricia Pozo-Rosich","doi":"10.1016/j.sedene.2024.01.001","DOIUrl":"10.1016/j.sedene.2024.01.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Headache is a very common neurological symptom. It is the first reason for consultation in neurology. About hospitalized patients, we do not have epidemiological data on the global prevalence of headaches in hospitalized patients.</div></div><div><h3>Objective</h3><div>To describe the prevalence of headaches in hospitalized patients, their triggers, and the level of compliance with nursing records.</div></div><div><h3>Methodology</h3><div>This is a descriptive, observational, and cross-sectional study at the Vall d’Hebron University Hospital (HUVH). The data collected were sociodemographic, related to the reason for admission and pain during admission. Statistical analysis was performed with R v4.1.1.</div></div><div><h3>Results</h3><div>Of the 45 admitted patients, 55% (25/45) participated, 55% (25/45) participated, 64% (16/25) were women. 60% (15/25) had presented headaches during admission, of which 73.3% (11/15) occurred in the last 24hours. The 33.3% (5/15) recognized stress as the most frequent trigger, noise (5/15), and income derivatives (3/15). During the daily follow-up by the nurse, 100% (25/25) of the patients answered that they had been asked about pain in general and 32% (8/25) specifically about headaches. No records were obtained due to the computer program's non-existence of nursing clinical variables.</div></div><div><h3>Conclussion</h3><div>Headache is a symptom that occurs prevalently in hospitalized patients. Stress and noise seem to be triggers of this situation. Certain behaviors on the part of health centers and professionals could help improve the care of these patients.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"61 ","pages":"Article 100159"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140405070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resumen del XXXI Congreso Anual y VII Congreso Internacional de la Sociedad Española de Enfermería Neurológica 西班牙神经病学学会第三十一届年度大会和第七届国际大会摘要

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-01-01 DOI: 10.1016/j.sedene.2025.500175

Paloma Muñoz Pedrazuela , Henar Garzón López , Ana Sofía Fernandes Ribeiro , Alejandro Lendínez Mesa , Maria Palanca Cámara , Tania Herrera Barcia , Eulàlia Giné-Ciprés , Raquel Vallejo de la Paz , Lourdes Bermelló López , Silvia Morel Fernández , Ana María Duro Martínez , Sergio González-Román Montalbán , Maria Figueras Jiménez , Verónica Hidalgo Benítez , David Iglesias Villanueva , Paloma Caro Muñoz , Fidel López Espuela

引用次数: 0

Eficacia de la realidad virtual en el grado de Alfabetización en Salud en los pacientes con ictus: ensayo clínico piloto aleatorizado 虚拟现实对中风患者健康素养的影响：随机试点临床试验

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-01-01 DOI: 10.1016/j.sedene.2024.03.001

Patricia Blázquez-González , Rubén Mirón-González , Alejandro Lendínez-Mesa , María Teresa Camacho Arroyo , Noelia Mancebo-Salas , Raquel Luengo-González , Silvia Herranz-Herranz , Roberto Antonio López Manrique , Jose Luis Cobo-Sánchez , Zulema González-Gancedo , María-Nieves Moro-Tejedor

{"title":"Eficacia de la realidad virtual en el grado de Alfabetización en Salud en los pacientes con ictus: ensayo clínico piloto aleatorizado","authors":"Patricia Blázquez-González , Rubén Mirón-González , Alejandro Lendínez-Mesa , María Teresa Camacho Arroyo , Noelia Mancebo-Salas , Raquel Luengo-González , Silvia Herranz-Herranz , Roberto Antonio López Manrique , Jose Luis Cobo-Sánchez , Zulema González-Gancedo , María-Nieves Moro-Tejedor","doi":"10.1016/j.sedene.2024.03.001","DOIUrl":"10.1016/j.sedene.2024.03.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the effectiveness of virtual reality on the degree of Health Literacy, before and after the use of virtual reality with the Nintendo Switch® device in patients with a diagnosis of stroke admitted to neurorehabilitation units.</div></div><div><h3>Methodology</h3><div>Twelve patients admitted to a neurorehabilitation unit underwent a 1:3 randomised clinical trial (intervention group: control group). The intervention group consisted of 4 patients and the control group consisted of 8 patients. The control group performed conventional rehabilitation and the intervention group, in addition to conventional rehabilitation, had a 20-minute virtual reality intervention once a week for 6 weeks. Clinical outcomes were measured for the literacy variable before the intervention and 6 weeks after the intervention in both the control group and the intervention group.</div></div><div><h3>Results</h3><div>An improvement in literacy was obtained in the control group (9 vs 9.38; p=0.18) and in the intervention group (13.75 vs 14.25; p=0.31) after the 6 weeks duration of the study. Comparing the intervention group and the control group, the literacy level of the intervention group was higher after the intervention than in the CG (14.25 vs. 9.38: p=0.20), but no statistically significant results were obtained.</div></div><div><h3>Conclusion</h3><div>Virtual reality used together with conventional treatment seems to improve the degree of literacy of stroke patients admitted to neurorehabilitation units.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"61 ","pages":"Article 100161"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluación de los neurofilamentos de cadena ligera en plasma como biomarcador de daño neuronal en la esclerosis múltiple 将血浆轻链神经丝作为多发性硬化症神经元损伤的生物标记物进行评估

Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica Pub Date : 2025-01-01 DOI: 10.1016/j.sedene.2024.03.002

Anibal Arteaga-Noriega , John Fredy Castro-Álvarez , José Zapata-Berruecos , Norma Liliana Muñoz Osorio , Johanna Gutiérrez-Vargas

{"title":"Evaluación de los neurofilamentos de cadena ligera en plasma como biomarcador de daño neuronal en la esclerosis múltiple","authors":"Anibal Arteaga-Noriega , John Fredy Castro-Álvarez , José Zapata-Berruecos , Norma Liliana Muñoz Osorio , Johanna Gutiérrez-Vargas","doi":"10.1016/j.sedene.2024.03.002","DOIUrl":"10.1016/j.sedene.2024.03.002","url":null,"abstract":"<div><h3>Introduction</h3><div>The identification of biomarkers of disease progression continues to be a necessity in the approach to multiple sclerosis (MS), a disabling neurological disease more common in young adults, which can have different phenotypes, among which the more notable are: relapsing-remitting, primary progressive and secondary progressive. Among biomarkers, the determination of neurofilament light chain (NfL) levels in both cerebrospinal fluid and serum have been shown to predict the severity of MS. Therefore, the objective of the present work was to evaluate the levels of NfL in patients in different stages of MS.</div></div><div><h3>Methodology</h3><div>A descriptive study was carried out, which included 70 patients diagnosed with MS; plasma NfL levels were analyzed using the adsorption enzyme immunoassay kit and the levels of the MS patients were compared with the levels of control patients<strong>.</strong></div></div><div><h3>Results</h3><div>In patients with MS, 87,14% were women, 21,43% were taking antidepressant drugs, 48,57% had vision complications, and 80% had spinal injuries. It was found that patients with relapsing-remitting phenotype and of male sex have higher levels of NfL.</div></div><div><h3>Conclusions</h3><div>The results show an increase in NfL in relapsing-remitting phenotype and in male patients, which suggests that there may be greater neuroaxonal deterioration in men and that they have this disease phenotype. However, future studies aimed at optimizing, standardizing, and implementing new technologies are necessary to address the predictive value of these biomarkers that can contribute to the management of the disease.</div></div>","PeriodicalId":38763,"journal":{"name":"Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica","volume":"61 ","pages":"Article 100162"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0