Silvio Vera-Vera, Artemio Garcia, Santiago Jimenez-Valero, Guillermo Galeote, Raúl Moreno, Alfonso Jurado-Roman
{"title":"Excimer Laser Coronary Atherectomy to Treat Calcified Lesions.","authors":"Silvio Vera-Vera, Artemio Garcia, Santiago Jimenez-Valero, Guillermo Galeote, Raúl Moreno, Alfonso Jurado-Roman","doi":"10.15420/icr.2022.10","DOIUrl":"https://doi.org/10.15420/icr.2022.10","url":null,"abstract":"We fully agree with the authors on the benefits of intravascular lithotripsy (IVL), a technology that has changed the treatment of calcified lesions because of its safety and efficacy, as well as having potential advantages over other plaque modification techniques. Its main limitation is the crossing profile when treating a very tight and severely calcified stenosis where rotational (RA) or orbital atherectomy (OA) are very useful, as the authors describe.","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e14"},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/77/icr-17-e14.PMC9585644.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40454595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierluigi Costanzo, Paul Bamborough, Mark Peterson, Djeven J Deva, Geraldine Ong, Neil Fam
{"title":"Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation With Dedicated Devices.","authors":"Pierluigi Costanzo, Paul Bamborough, Mark Peterson, Djeven J Deva, Geraldine Ong, Neil Fam","doi":"10.15420/icr.2021.19","DOIUrl":"https://doi.org/10.15420/icr.2021.19","url":null,"abstract":"<p><p>Aortic regurgitation (AR) is not the most common valvular disease; however, its prevalence increases with age, with more than 2% of those aged >70 years having at least moderate AR. Once symptoms related to AR develop, the prognosis becomes poor. Transcatheter aortic valve implantation for patients with pure severe AR and at prohibitive surgical risk is occasionally performed, but remains a clinical challenge due to absence of valvular calcium, large aortic root and increased stroke volume. These issues make the positioning and deployment of transcatheter aortic valve implantation devices unpredictable, with a tendency to prosthesis embolisation or malposition. To date, the only two dedicated transcatheter valves for AR are the J-Valve (JC Medical) and the JenaValve (JenaValve Technology). Both devices have been used successfully via the transapical approach. The transfemoral experience is limited to first-in-human publications and to a clinical trial dedicated to AR, for which the completion date is still pending.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e11"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/6d/icr-17-e11.PMC9340575.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40669217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patrick Vera Cruz, Patricio Palmes, Nadine Bacalangco
{"title":"Prognostic Value of Myocardial Blush Grade in ST-elevation MI: A Systematic Review and Meta-analysis.","authors":"Patrick Vera Cruz, Patricio Palmes, Nadine Bacalangco","doi":"10.15420/icr.2022.01","DOIUrl":"https://doi.org/10.15420/icr.2022.01","url":null,"abstract":"<p><p><b>Background:</b> Ineffective myocardial perfusion despite angiographic success after angioplasty occurs frequently and is associated with an increased risk of mortality. Hence, this study determined whether myocardial perfusion measured by myocardial blush grade (MBG) identifies ST-elevation MI (STEMI) patients at high risk for poor outcomes after successful angioplasty. <b>Methods:</b> The search employed strategies designed for research databases. An article was eligible if it included adults who underwent coronary angioplasty for STEMI, post-angioplasty MBG was assessed, and mortality or major adverse cardiovascular events (MACE) were determined. Risk for bias was assessed using the Quality In Prognosis Studies tool and forest plots in a Mantel-Haenszel fixed effects model were created using RevMan5.4. <b>Results/discussion:</b> Eight observational studies with an overall low risk of bias were included, involving 8,044 patients. MBG 0/1 with no to poor myocardial perfusion had a negative prognostic value for mortality (OR 2.68; 95% CI [2.22-3.23]) and MACE (OR 1.20; 95% CI [1.01-1.41]). Furthermore, MBG 2 with moderate myocardial perfusion and MBG 3 with normal myocardial perfusion were associated with increased survival with a logHR of 0.47 (95% CI [0.43-0.52]) and 0.20 percutaneous coronary intervention (95% CI [0.18-0.23]). These results imply MBG is a useful prognostic marker for STEMI patients. <b>Conclusion:</b> MBG 0/1 after primary angioplasty is a strong negative prognostic marker for long-term all-cause mortality and MACE among STEMI patients, and a post-primary angioplasty MBG of 2 or 3 is a robust prognostic marker for long-term survival.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/65/icr-17-e10.PMC9340576.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40669215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan A Mailey, Patrick Thompson, Paul W Johnston, Colum G Owens
{"title":"A Complex Case of Pregnancy-related Left Main Stem Spontaneous Coronary Artery Dissection.","authors":"Jonathan A Mailey, Patrick Thompson, Paul W Johnston, Colum G Owens","doi":"10.15420/icr.2021.33","DOIUrl":"https://doi.org/10.15420/icr.2021.33","url":null,"abstract":"<p><p>Spontaneous coronary artery dissection (SCAD) is a less common cause of acute coronary syndrome. Pregnancy-related SCAD is uncommon, but often presents with a more severe phenotype. This report describes a 30-year-old woman with an anterior ST elevation MI, presenting 1 day postpartum. Left main stem (LMS) SCAD with extensive intramural haematoma (IMH) and resultant LMS occlusion was confirmed by angiography and intravascular imaging. Given the extent of disease, the patient underwent emergency cardiac surgery. Coronary flow was initially improved by decompressing the IMH using cutting balloons. The coronary wires were successfully left <i>in situ</i> during transfer in an effort to both maintain flow and allow the surgeon to identify true LMS. Ideally, SCAD can be managed conservatively given the risk of intervention worsening IMH, and hence myocardial ischaemia/MI. However, emergency revascularisation is indicated in cases of persistent ischaemia. This case demonstrates percutaneous therapies to bridge towards and help with subsequent surgical revascularisation.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e09"},"PeriodicalIF":0.0,"publicationDate":"2022-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a3/c4/icr-17-e09.PMC9306263.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40632958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helen Routledge, Andrew Sp Sharp, Jan Kovac, Mark Westwood, Thomas R Keeble, Raj Bathula, Hany Eteiba, Iris Q Grunwald, Nick Curzen
{"title":"Can Interventional Cardiologists Help Deliver the UK Mechanical Thrombectomy Interventional Programme for Patients with Acute Ischaemic Stroke? A Discussion Paper from the British Cardiovascular Interventional Society Stroke Thrombectomy Focus Group.","authors":"Helen Routledge, Andrew Sp Sharp, Jan Kovac, Mark Westwood, Thomas R Keeble, Raj Bathula, Hany Eteiba, Iris Q Grunwald, Nick Curzen","doi":"10.15420/icr.2021.35","DOIUrl":"https://doi.org/10.15420/icr.2021.35","url":null,"abstract":"<p><p>There is a willingness among UK interventional cardiologists to contribute to provision of a 24/7 mechanical thrombectomy (MT) service for all suitable stroke patients if given the appropriate training. This highly effective intervention remains unavailable to the majority of patients who might benefit, partly because there is a limited number of trained specialists. As demonstrated in other countries, interdisciplinary working can be the solution and an opportunity to achieve this is outlined in this article.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e07"},"PeriodicalIF":0.0,"publicationDate":"2022-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/ea/icr-17-e07.PMC9214600.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40553255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Best Practice in Intravascular Lithotripsy.","authors":"Benjamin Honton, Jacques Monsegu","doi":"10.15420/icr.2021.14","DOIUrl":"https://doi.org/10.15420/icr.2021.14","url":null,"abstract":"<p><p>Intravascular lithotripsy (IVL) is a novel approach to lesion preparation of severely calcified plaques in coronary and peripheral vessels. Lithotripsy is delivered by vaporising fluid to create an expanding bubble that generates sonic pressure waves that interact with arterial calcification. Available data indicate that IVL leads to increased vessel compliance before stent implantation with high efficacy and an excellent safety profile. Since it gained the CE mark in 2017, and with improved operator experience, the use of IVL has expanded into more complex clinical situations. This review focuses on the best practice for IVL use in the cath lab, based on 3 years of experience with the technology and the latest scientific data from the Disrupt CAD clinical trials.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e02"},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/ac/icr-17-e02.PMC8826142.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39611698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kush P Patel, Thomas A Treibel, Paul R Scully, Michael Fertleman, Samuel Searle, Daniel Davis, James C Moon, Michael J Mullen
{"title":"Futility in Transcatheter Aortic Valve Implantation: A Search for Clarity.","authors":"Kush P Patel, Thomas A Treibel, Paul R Scully, Michael Fertleman, Samuel Searle, Daniel Davis, James C Moon, Michael J Mullen","doi":"10.15420/icr.2021.15","DOIUrl":"10.15420/icr.2021.15","url":null,"abstract":"<p><p>Although transcatheter aortic valve implantation (TAVI) has revolutionised the landscape of treatment for aortic stenosis, there exists a cohort of patients where TAVI is deemed futile. Among the pivotal high-risk trials, one-third to half of patients either died or received no symptomatic benefit from the procedure at 1 year. Futility of TAVI results in the unnecessary exposure of risk for patients and inefficient resource utilisation for healthcare services. Several cardiac and extra-cardiac conditions and frailty increase the risk of mortality despite TAVI. Among the survivors, these comorbidities can inhibit improvements in symptoms and quality of life. However, certain conditions are reversible with TAVI (e.g. functional mitral regurgitation), attenuating the risk and improving outcomes. Quantification of disease severity, identification of reversible factors and a systematic evaluation of frailty can substantially improve risk stratification and outcomes. This review examines the contribution of pre-existing comorbidities towards futility in TAVI and suggests a systematic approach to guide patient evaluation.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":" ","pages":"e01"},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/4b/icr-17-e01.PMC8790725.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Xinguo Fang, Arthur Sze-Yue Yung, Simon Cheung-Chi Lam, Frankie Chor-Cheung Tam
{"title":"Coronary Intravascular Lithotripsy in a Tight Circumferential Calcified Lesion in the Presence of Haematoma Extending into Left Main Coronary Artery After Rotational Atherectomy.","authors":"Jonathan Xinguo Fang, Arthur Sze-Yue Yung, Simon Cheung-Chi Lam, Frankie Chor-Cheung Tam","doi":"10.15420/icr.2021.18","DOIUrl":"https://doi.org/10.15420/icr.2021.18","url":null,"abstract":"<p><p>Calcified disease increases procedural challenges and is associated with worse outcomes in percutaneous coronary intervention. Coronary intravascular lithotripsy is a new balloon-based modality for treating calcified disease with deep circumferential calcification. Its main benefit is simplicity and safety compared to atherectomy. However, atherectomy remains the modality of choice in balloon-uncrossable lesions. More than one modality is often needed for treatment of calcified disease. The authors present a case of a balloon-uncrossable calcified ostial left circumflex lesion which was first treated with rotational atherectomy. However, there was haematoma formation in the ostial circumflex extending into left main coronary artery, together with suboptimal preparation of calcified disease. Intravascular coronary lithotripsy was then used to successfully prepare the calcified lesion for stenting without causing extension of the haematoma.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"17 ","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/7f/icr-17-e12.PMC10437410.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10405632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Mion, Rupert Simpson, Tom Johnson, Valentino Oriolo, Ellie Gudde, Paul Rees, Tom Quinn, Von Johannes Vopelius-Feldt, Sean Gallagher, Abdul Mozid, Nick Curzen, John Davies, Paul Swindell, Nilesh Pareek, Thomas R Keeble
{"title":"British Cardiovascular Intervention Society Consensus Position Statement on Out-of-hospital Cardiac Arrest 2: Post-discharge Rehabilitation.","authors":"Marco Mion, Rupert Simpson, Tom Johnson, Valentino Oriolo, Ellie Gudde, Paul Rees, Tom Quinn, Von Johannes Vopelius-Feldt, Sean Gallagher, Abdul Mozid, Nick Curzen, John Davies, Paul Swindell, Nilesh Pareek, Thomas R Keeble","doi":"10.15420/icr.2022.08","DOIUrl":"https://doi.org/10.15420/icr.2022.08","url":null,"abstract":"<p><p>Out-of-hospital cardiac arrest (OHCA) is a major public health issue that poses significant challenges both in immediate management and long-term follow-up. Survivors of OHCA often experience a combination of complex medical, physical and psychological needs that have a significant impact on quality of life. Guidelines suggest a multi-dimensional follow-up to address both physical and non-physical domains for survivors. However, it is likely that there is substantial unwarranted variation in provision of services throughout the UK. Currently, there is no nationally agreed model for the follow-up of OHCA survivors and there is an urgent need for a set of standards and guidelines in order to ensure equal access for all. Accordingly, the British Cardiovascular Interventional Society established a multi-disciplinary working group to develop a position statement that summarises the most up-to-date evidence and provides guidance on essential and desirable services for a dedicated follow-up pathway for survivors of OHCA.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"17 ","pages":"e19"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b4/25/icr-17-e19.PMC9820137.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9085616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of High- or Moderate-intensity Rosuvastatin on 1-year Major Adverse Cardiovascular Events Post-percutaneous Coronary Intervention.","authors":"Morteza Chehrevar, Reza Golchin Vafa, Mohammadhossein Rahmani, Mohammadjavad Mehdizadeh Parizi, Amin Ahmadi, Bardia Zamiri, Reza Heydarzadeh, Mohammad Montaseri, Seyed Ali Hosseini, Javad Kojuri","doi":"10.15420/icr.2022.13","DOIUrl":"https://doi.org/10.15420/icr.2022.13","url":null,"abstract":"<p><p><b>Background:</b> Although statins decrease mortality in coronary artery disease, the effect of high-dose statins and duration of therapy post-percutaneous coronary intervention (PCI) is not well addressed. <b>Aim:</b> To determine the effective dose of statin to prevent major adverse cardiovascular events (MACEs), such as acute coronary syndrome, stroke, myocardial infarction, revascularisation and cardiac death, after PCI in patients with chronic coronary syndrome. <b>Methods:</b> In this randomised, double-blind clinical trial, all chronic coronary syndrome patients with a recent history of PCI were randomly divided into two groups after 1 month of high-dose rosuvastatin therapy. Over the next year, the first group received rosuvastatin 5 mg daily (moderate intensity), while the second received rosuvastatin 40 mg daily (high intensity). Participants were evaluated in terms of high-sensitivity C-reactive protein and MACEs. <b>Results:</b> The 582 eligible patients were divided into group 1 (n=295) and group 2 (n=287). There was no significant difference between the two groups in terms of sex, age, hypertension, diabetes, smoking, previous history of PCI or history of coronary artery bypass grafting (p>0.05). There were no statistically significant differences in MACE and high-sensitivity C-reactive protein after 1 year between the two groups (p=0.66). <b>Conclusion:</b> The high-dose group had lower LDL levels. However, given the lack of association between high-intensity statins and MACEs in the first year after PCI among chronic coronary syndrome patients, the use of moderate-intensity statins may be as effective as high-intensity statins, and treatment based on LDL targets may suffice.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"17 ","pages":"e20"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/52/47/icr-17-e20.PMC9987507.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9089966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}