Ahmad Edris, Yosef Manla, Firas Al Badarin, Khwaja Hasan, Shahrukh Hashmani, Mahmoud Traina, Dhiaedin Khiati, Amani Khalouf, Anas El Zouhbi, Emin Murat Tuzcu
{"title":"Outcomes of Transcatheter Aortic Valve Replacement in the United Arab Emirates: Real-world, Single-centre Experience from an Emerging Programme.","authors":"Ahmad Edris, Yosef Manla, Firas Al Badarin, Khwaja Hasan, Shahrukh Hashmani, Mahmoud Traina, Dhiaedin Khiati, Amani Khalouf, Anas El Zouhbi, Emin Murat Tuzcu","doi":"10.15420/icr.2022.04","DOIUrl":"https://doi.org/10.15420/icr.2022.04","url":null,"abstract":"<p><strong>Background: </strong>Data on outcomes of transcatheter aortic valve replacement (TAVR) in the Middle East, particularly in the United Arab Emirates (UAE), are limited. Whether centres with a low volume of patients requiring the procedure can achieve similar outcomes as those reported in pivotal clinical trials remains unclear. This study evaluates procedural outcomes of patients undergoing TAVR in a newly established programme in the UAE.</p><p><strong>Methods: </strong>Procedural outcomes of consecutive patients who underwent transfemoral TAVR at a single centre in the UAE between January 2016 and November 2021 were compared with those at centres in the lowest quartile (Q1) of procedural volume in the Transcatheter Valve Therapy Registry, which covers centres in the US.</p><p><strong>Results: </strong>Among the 183 patients included in the study, the median age was 76 years (interquartile range [IQR] 71-82), and 42.1% of patients were women, with a median Society of Thoracic Surgeons predicted risk of mortality score of 4.6 (IQR 2.9-7.5). Most of the patients (93.3%) received a balloon-expandable valve. All-cause death within 30 days, stroke and major vascular complications occurred in 0.6%, 0.6% and 2.2% of patients, respectively, compared with 3.1%, 2.2% and 4% in patients treated at Q1 hospitals.</p><p><strong>Conclusion: </strong>Patients undergoing transfemoral TAVR at an emerging centre in the Middle East had favourable outcomes compared with those performed at Q1 hospitals in the US. These findings suggest that careful patient selection for TAVR is critical and may help optimise patient outcomes, especially when procedural volumes are low.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e08"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/43/icr-18-e08.PMC10433106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is It Really Safe to Discontinue Antiplatelet Therapy 12 Months After Percutaneous Coronary Intervention in Patients with Atrial Fibrillation?","authors":"Balen Abdulrahman, Richard J Jabbour, Nick Curzen","doi":"10.15420/icr.2022.40","DOIUrl":"https://doi.org/10.15420/icr.2022.40","url":null,"abstract":"<p><p>The prevalence of AF in patients with coronary artery disease is high. The guidelines from many professional groups, including the European Society of Cardiology, American College of Cardiology/American Heart Association and Heart Rhythm Society, recommend a maximum duration of 12 months of combination single antiplatelet and anticoagulation therapy in patients who undergo percutaneous coronary intervention and who have concurrent AF, followed by anticoagulation alone beyond 1 year. However, the evidence that anticoagulation alone without antiplatelet therapy adequately reduces the well-documented attritional risk of stent thrombosis after coronary stent implantation is relatively sparse, particularly given that very late stent thrombosis (>1 year from stent implantation) is the commonest type. By contrast, the elevated risk of bleeding from combined anticoagulation and antiplatelet therapy is clinically important. The aim of this review is to assess the evidence for long-term anticoagulation alone without antiplatelet therapy 1 year post-percutaneous coronary intervention in patients with AF.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e22"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/13/icr-18-e22.PMC10331563.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9812934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diarmaid Cadogan, Marwa Daghem, Mostafa Snosi, Lynne K Williams, Jonathan Weir-McCall, Patrick A Calvert, Joel P Giblett
{"title":"Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention.","authors":"Diarmaid Cadogan, Marwa Daghem, Mostafa Snosi, Lynne K Williams, Jonathan Weir-McCall, Patrick A Calvert, Joel P Giblett","doi":"10.15420/icr.2023.01","DOIUrl":"https://doi.org/10.15420/icr.2023.01","url":null,"abstract":"<p><p>Post-infarction ventricular septal defect is a mechanical complication of acute MI. The incidence of this complication is low in the primary percutaneous coronary intervention era. However, the associated mortality is very high at 94% with medical management alone. Open surgical repair or percutaneous transcatheter closure still has an in-hospital mortality >40%. Retrospective comparisons between both closure methods are limited by observation and selection bias. This review addresses the assessment and optimisation of patients prior to repair, the optimal timing of repair, and the limitations in current data. The review considers techniques for percutaneous closure, and finally considers the path that future research should take to improve outcomes for patients.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e19"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/be/de/icr-18-e19.PMC10331564.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9818465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roland Schmieder, Michel Burnier, Cara East, Konstantinos Tsioufis, Sean Delaney
{"title":"Renal Denervation: A Practical Guide for Health Professionals Managing Hypertension.","authors":"Roland Schmieder, Michel Burnier, Cara East, Konstantinos Tsioufis, Sean Delaney","doi":"10.15420/icr.2022.38","DOIUrl":"https://doi.org/10.15420/icr.2022.38","url":null,"abstract":"<p><p>Growing evidence demonstrates the suitability of renal denervation in a broad population of patients; however, questions remain over its suitability and practical implementation. Given the rapidity of emerging data, this has been a challenging field for potential adopters to navigate. The purpose of this article is twofold: to provide navigation through emerging clinical data and evolving guidance; and to provide physicians with practical, evidence-based advice for identifying eligible patients and providing appropriate management in the pre- and postintervention settings. Although many of these recommendations are based on existing published guidance documents, we reflect equally on our own experiences of using this technology.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e06"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/42/35/icr-18-e06.PMC10433107.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myval: A Novel Transcatheter Heart Valve for the Treatment of Severe Aortic Stenosis.","authors":"Ashok Seth, Vijay Kumar, Vivudh Pratap Singh, Dhananjay Kumar, Puneet Varma, Vishal Rastogi","doi":"10.15420/icr.2020.32","DOIUrl":"https://doi.org/10.15420/icr.2020.32","url":null,"abstract":"<p><p>Transcatheter aortic valve implantation (TAVI) performed using femoral arterial access is now a guideline recommended treatment for severe calcific aortic stenosis (AS) in elderly patients. Technological advancements and procedural refinements have focused on making TAVI simpler, safer, more effective and durable. Myval (Meril Lifesciences) is a new generation balloon-expandable transcatheter heart valve (THV) developed in India that possesses novel features to improve deliverability and aid precise deployment. Following the first-in-human study, Myval was approved in India for commercial implantation in October 2018 and was subsequently given a CE mark in April 2019. This article reviews the science, technology and up-to-date clinical evidence for the Myval THV.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6c/87/icr-18-e12.PMC10311401.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9737632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johny Nicolas, Nicholas L Pitaro, Birgit Vogel, Roxana Mehran
{"title":"Artificial Intelligence - Advisory or Adversary?","authors":"Johny Nicolas, Nicholas L Pitaro, Birgit Vogel, Roxana Mehran","doi":"10.15420/icr.2022.22","DOIUrl":"https://doi.org/10.15420/icr.2022.22","url":null,"abstract":"Artificial intelligence (AI) leverages computers and machines capable of performing high-level executive functions, mimicking human intelligence. Machine learning (ML) is a branch of AI capable of improving itself by learning from data, identifying patterns and making decisions without being explicitly programmed to do so. AI is already part of everyday life and used in areas including healthcare, banking systems and industry. In particular, AI has numerous applications in medicine, such as risk prediction, robotic surgery, automated imaging diagnosis and clinical research.1,2 Cardiology is at the forefront of the AI revolution, and there are many potential applications. Though concerns with AI credibility are more of an issue in healthcare than in other fields, the potential benefits of well-integrated AI tools for medicine in general and cardiology in particular are fascinating.","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e17"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/3e/icr-18-e17.PMC10311397.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9743976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maja Rojko, Natasa Cernic Suligoj, Metka Zorc, Marko Noc
{"title":"Patent Foramen Ovale-associated Stroke and COVID-19 Vaccination.","authors":"Maja Rojko, Natasa Cernic Suligoj, Metka Zorc, Marko Noc","doi":"10.15420/icr.2022.27","DOIUrl":"https://doi.org/10.15420/icr.2022.27","url":null,"abstract":"<p><p><b>Background:</b> COVID-19 infection has been associated with paradoxical thromboembolism through a patent foramen ovale (PFO) and ischaemic stroke. Such events have not been reported after COVID-19 vaccination. The aim of the present study was to investigate PFO-associated stroke during the mass COVID-19 vaccination in Slovenia. <b>Methods:</b> This prospective study, conducted between 26 December 2020 and 31 March 2022, enrolled consecutive patients (≥18 years) with PFO-associated stroke referred for a percutaneous closure to a single interventional facility in Slovenia. <b>Results:</b> A total of 953,546 people aged between 18 and 70 years received at least one dose of a COVID-19 vaccine approved by the European Medicines Agency. Of the 28 patients presenting with PFO-associated stroke, 12 patients (42.9%) were vaccinated prior to the event, of whom nine were women and three were men, aged between 21 and 70 years. Stroke occurred within 35 days after vaccination in six patients (50%). Clinical presentation included motor dysphasia, paresis, vertigo, ataxia, paraesthesia, headache, diplopia and hemianopia. At hospital discharge, 11 patients (91.6%) had at least one residual ischaemic lesion. <b>Conclusion:</b> A temporal coincidence of COVID-19 vaccination and PFO-associated stroke has been described. A potential cause-effect relationship may only be hypothesised.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/67/icr-18-e10.PMC10311394.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9746309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contemporary Left Main Percutaneous Coronary Intervention: A State-of-the-art Review.","authors":"Refai Showkathali, Radha Priya Yalamanchi","doi":"10.15420/icr.2023.02","DOIUrl":"https://doi.org/10.15420/icr.2023.02","url":null,"abstract":"<p><p>The majority of the left ventricular myocardium is supplied by the left main coronary artery. Atherosclerotic obstruction of the left main coronary artery therefore leads to significant myocardial jeopardy. Coronary artery bypass surgery (CABG) has been the gold standard for left main coronary artery disease in the past. However, advancements in technology have established percutaneous coronary intervention (PCI) as a standard, safe and reasonable alternative to CABG, with comparable outcomes. Contemporary PCI of left main coronary artery disease comprises careful patient selection, accurate technique guided by either intravascular ultrasound or optical coherence tomography and - if necessary - physiological assessment using fractional flow reserve. This review focuses on current evidence from registries and randomised trials comparing PCI with CABG, procedural tips and tricks, adjuvant technologies and the triumph of PCI.</p>","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"18 ","pages":"e20"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/11/icr-18-e20.PMC10331562.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9818462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"British Cardiovascular Interventional Society Consensus: a Huge Step Towards Standardised Care for Out-of-hospital Cardiac Arrest in the UK.","authors":"Marko Noc, Roxana Mehran","doi":"10.15420/icr.2022.25","DOIUrl":"10.15420/icr.2022.25","url":null,"abstract":"","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"17 ","pages":"e17"},"PeriodicalIF":0.2,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/55/icr-17-e17.PMC9820175.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9099881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous Coronary Intervention in Anomalous Right Coronary Artery: Ready to Implement in Clinical Routine?","authors":"Anselm W Stark, Christoph Gräni","doi":"10.15420/icr.2022.17","DOIUrl":"10.15420/icr.2022.17","url":null,"abstract":"","PeriodicalId":38586,"journal":{"name":"Interventional Cardiology Review","volume":"17 ","pages":"e15"},"PeriodicalIF":0.2,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/bc/icr-17-e15.PMC9819999.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9085611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}