L. Iacoviello, A. Di Castelnuovo, Livia Rago, M. Vaglio, F. Badilini, D. Assanelli, M. Donati, G. de Gaetano
{"title":"Computerised ECG repository in the Moli-sani project","authors":"L. Iacoviello, A. Di Castelnuovo, Livia Rago, M. Vaglio, F. Badilini, D. Assanelli, M. Donati, G. de Gaetano","doi":"10.1109/ESGCO.2014.6847532","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847532","url":null,"abstract":"Computerized electrocardiogram (ECG) may be extremely useful to develop new tools for the definition of the risk and the prevention of cardiovascular disease. The Moli-sani project (http://www.moli-sani.org) is a population-based cohort study that recruited over 24.000 men and women, aged >35 year, from the general population. The aim was the evaluation of risk factors linked to chronic-degenerative disease with particular regard to cardiovascular disease and cancer and intermediate metabolic phenotypes such as hypertension, diabetes, dyslipidemia, obesity, and metabolic syndrome. Standard 12-lead resting ECG was performed by a Cardiette ar2100-view electrocardiograph and tracings stored in digital standard communication protocol format for subsequent analysis. The digital ECG database of the Moli-sani project is currently being used to assess the association between physiologic variables, pathophysiologic conditions such as hypertension, diabetes and obesity and parameters derived from the ECG signal. This is a comprehensive review of the database and of the results until now obtained with its analysis.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127496619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Mastantuono, D. Lapi, L. Battiloro, M. Cesarelli, G. D'Addio, L. Iuppariello, A. Colantuoni
{"title":"Microvascular blood flow regulation impairments in hypertensive obese people","authors":"T. Mastantuono, D. Lapi, L. Battiloro, M. Cesarelli, G. D'Addio, L. Iuppariello, A. Colantuoni","doi":"10.1109/ESGCO.2014.6847584","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847584","url":null,"abstract":"Hypertension causes several microvascular alterations, leading to inadequate blood supply to tissues and target-organ damage. The present study was aimed to investigate microvascular skin blood flow and related oscillations in hypertensive obese subjects. Twenty-eight controls and twenty-seven hypertensive patients were recruited from our Outpatient Clinics. Anthropometric measurements were evaluated and bioimpedance analysis was performed. Finally, skin microvascular blood flow was measured by a laser Doppler flowmeter and oscillations in blood flow were analyzed by power spectrum analysis. Newly diagnosed hypertensive subjects showed lower mean skin blood flow as well as lower related total power spectral density compared to the controls. In these patients, moreover, power spectral analysis of microvascular oscillations indicate a lower spectral density of the frequency component related to myogenic activity compared to controls. Therefore, hypertension appears to be associated to myogenic impairments, causing changes in microvascular modulation and tissue perfusion.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128995506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vagal effects on heart rate: Different between up and down","authors":"J. Karemaker","doi":"10.1109/ESGCO.2014.6847524","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847524","url":null,"abstract":"The vagus nerves of rabbits under anesthesia were stimulated to test the effects on heart rate. Repeated stimuli were delivered either at a constant frequency (`tetanic') or in short bursts, one burst per heartbeat (`pulsatile stimulation') at variable moments in the cardiac cycle. The heart rate dynamics in response to short-lasting increases or decreases of ongoing stimulation were studied. Strong stimuli had a short-delay effect on heart rate: 100-120 ms; if stimulation was pulsatile the effects of decreased vagal stimulation could influence the ongoing cycle. However, in the case of tetanic stimulation the delay was much longer, up to 300 ms. It is concluded that observed changes in heart rate from one beat to the next are not always due to the same changes in underlying vagal activity. When using heart rate variability to probe the autonomic nervous system one should realize that the probe itself is highly non-linear.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127921715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascular resistance at low frequencies may explain the physiological role of Mayer waves: A fractal arterial tree model study","authors":"T. Buchner, Tomasz Sobiech","doi":"10.1109/ESGCO.2014.6847575","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847575","url":null,"abstract":"We numerically investigate a 1-D mathematical model of blood flow related with harmonic blood pressure modes (BP) in the fractal model of a human arterial tree [1]. We calculated the model admittance: inverse of the Total Peripheral Resistance (TPR) as a function of frequency. We show that the peak of admittance (maximum flow) may appear at low frequency, below 1 Hz. Total flow in presence of such low frequency oscillations is higher than without it. Introduction of these oscillations by cardiovascular regulatory loops may provide a supplementary mechanism which can increase the total blood flow (venous return) in situations of increased demand. The result may add new value to the analysis of the Mayer waves.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133510798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Piper, Britta Pester, K. Schiecke, F. Benninger, M. Feucht, H. Witte
{"title":"Tensor decomposition of time-variant coherence between heart rate variability and EEG envelopes in children with epilepsy","authors":"D. Piper, Britta Pester, K. Schiecke, F. Benninger, M. Feucht, H. Witte","doi":"10.1109/ESGCO.2014.6847543","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847543","url":null,"abstract":"Time-variant coherence between the heart rate variability and the channel-related envelopes of the EEG delta activity was used as an indicator for interactions between the autonomic nervous system and cortical processes before, during and after epileptic seizures. The tensor decomposition was applied to explore the topography-time-frequency characteristics of these correlative interactions for each patient and for two sub-groups (left and right hemispheric seizure). It can be demonstrated that tensor decomposition strongly supports the interaction analysis and its interpretation.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130172868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcello Ruspi, S. Carugo, M. Slavich, D. Palin, M. T. Gatti, Agata Basile, Virginia Natale, Paolo Gonella Pacchiotti, A. De Giuli, Carlo Enrico Venturi
{"title":"Healthcare and remote monitoring system solution on the cloud our clinical experience on 100 patients","authors":"Marcello Ruspi, S. Carugo, M. Slavich, D. Palin, M. T. Gatti, Agata Basile, Virginia Natale, Paolo Gonella Pacchiotti, A. De Giuli, Carlo Enrico Venturi","doi":"10.1109/ESGCO.2014.6847571","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847571","url":null,"abstract":"The Authors were involved in a free of charge clinical trial on 100 patients suffering from arrhythmia, using a medical device FDA-cleared and CE-medical marked on a cloud-based platform. The trial, conducted in Sanpietro Medical Center in downtown Milan during the months of November and December 2013, was aimed to confirm the adherence of the solution to our defined clinical protocol, the performance of the device vs. the already known initial diseases, and to test the platform on the cloud, to detect possible technical and clinical issues, the signal quality and adverse events. The overall satisfaction level was high: a system based on continuous remote patients monitoring while they live their normal daily lives, with clinical access anywhere and anytime, allows a better control of therapies, can save healthcare cost and reduce readmissions.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131833496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Masè, A. Graffigna, S. Sinelli, S. Restivo, F. Ravelli
{"title":"Unified framework for the combined assessment of autonomic function and ectopic activity before post-operative atrial fibrillation","authors":"M. Masè, A. Graffigna, S. Sinelli, S. Restivo, F. Ravelli","doi":"10.1109/ESGCO.2014.6847497","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847497","url":null,"abstract":"The mechanisms underlying the onset of postoperative atrial fibrillation (POAF) are still poorly understood. Enhanced atrial automaticity and alterations in autonomic tone following surgery have been suggested as critical predisposing factors. This paper proposes an unified framework for the combined analysis of ectopic activity and autonomic function preceding POAF. Atrial intervals series were automatically extracted from long-term atrial signal recordings in postoperative patients, and processed with an adaptive filter to separate normal from abnormal beats. Normal intervals were addressed to classical frequency-domain heart rate variability analysis, while ectopic beats were further processed to characterize their occurrence, coupling interval distribution and type. Preliminary application of the analysis showed concurrent changes in autonomic function and ectopic activity in the three hours preceding POAF onset. These results suggest the potential of the combined analysis to disclose interaction patterns between autonomic tone and automaticity leading to the onset of post-operative arrhythmias.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134457103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Segmentation of nocturnal Holter-ECG recordings with respect to different recumbent body positions","authors":"C. Maier, A. Benz, H. Dickhaus","doi":"10.1109/ESGCO.2014.6847568","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847568","url":null,"abstract":"This paper evaluates a previously developed approach for minute-by-minute segmentation of night-time ECG recordings with respect to periods of different recumbent body positions (BPs). It is based on recurrence analysis of 8D-feature vectors aggregating the area under the QRS complex in eight Holter-ECG leads. The number and consistency of ECG-derived BPs was compared to reference BPs (45° resolution) extracted from 139 polysomnograms (PSGs, 120 subjects). The results indicate a high BP resolution for the ECG. Up to 3 ECG BPs per PSG BP were identified in 70% of the cases. In 60% of the ECGs, the fraction of inconsistent epoch assignments was ≤10%, and ≤30% of BP changes in the PSG were undetected. When adjacent PSG BPs were considered exchangeable, the results improved significantly, indicating a potentially unfavorable effect of the PSG sensor discretization and encouraging further steps towards the absolute classification of BPs at least in coarse categories.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132216664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Makowiec, Z. Struzik, B. Graff, G. Graff, D. Wejer, A. Kaczkowska, Joanna Wdowczyk-Szulc, Marta Buchowiecka
{"title":"Network approach to increments of RR-intervals for visualization of dynamics of cardiac regulation","authors":"D. Makowiec, Z. Struzik, B. Graff, G. Graff, D. Wejer, A. Kaczkowska, Joanna Wdowczyk-Szulc, Marta Buchowiecka","doi":"10.1109/ESGCO.2014.6847576","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847576","url":null,"abstract":"The transition network for RR-increments is presented in a directed and weighted graph, with vertices representing RR-increments and edges corresponding to the order in a sequence of increments. The adjacency matrix and the transition matrix of this network provide a graphical tool which could be useful in the assessment of cardiac regulation. As an example, the method is applied in detecting differences between diurnal activity and nocturnal rest.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"26 64","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132546812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bizzego, Marco Mina, Calogero Zarbo, G. Esposito, Cesare Furlanello
{"title":"Physiolyze: A Galaxy-based web service for Heart Rate Variability analysis with online processing","authors":"A. Bizzego, Marco Mina, Calogero Zarbo, G. Esposito, Cesare Furlanello","doi":"10.1109/ESGCO.2014.6847537","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847537","url":null,"abstract":"We developed Physiolyze, a Galaxy-based web framework to process Heart Rate Variability (HRV) data. Our framework includes the pyHRV library, an up-to-date collection of Python methods to calculate HRV indexes. Physiolyze can be used both through a web interface and a web service component for a fast and configurable embedding of HRV analysis in complex processing pipelines. The framework also provides support for online processing of heart rate streaming data.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130748766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}