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MuTE: A new Matlab toolbox for estimating the multivariate Transfer entropy in physiological variability series 一个新的Matlab工具箱，用于估计生理变异序列中的多变量传递熵
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-07-08 DOI: 10.1109/ESGCO.2014.6847518
A. Montalto, L. Faes, Daniele Marinazzo
{"title":"MuTE: A new Matlab toolbox for estimating the multivariate Transfer entropy in physiological variability series","authors":"A. Montalto, L. Faes, Daniele Marinazzo","doi":"10.1109/ESGCO.2014.6847518","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847518","url":null,"abstract":"We present a new time series analysis toolbox, developed in Matlab, for the estimation of the Transfer entropy (TE) between time series taken from a multivariate dataset. The main feature of the toolbox is its fully multivariate implementation, that is made possible by the design of an approach for the non-uniform embedding (NUE) of the observed time series. The toolbox is equipped with parametric (linear) and non-parametric (based on binning or nearest neighbors) entropy estimators. All these estimators, implemented using the NUE approach in comparison with the classical approach based on uniform embedding, are tested on RR interval, systolic pressure and respiration variability series measured from healthy subjects during head-up tilt. The results support the necessity of resorting to NUE for obtaining reliable estimates of the multivariate TE in short-term cardiovascular and cardiorespiratory variability.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125842244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Comparison between permutation and coarse-grained entropy approaches for the assessment of short-term complexity of heart period variability 排列法与粗粒度熵法评估心脏周期变异性短期复杂性的比较
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847492
A. Porta, V. Bari, A. Marchi, T. Bassani, P. Castiglioni, M. Di Rienzo, A. Cividjian, L. Quintin
{"title":"Comparison between permutation and coarse-grained entropy approaches for the assessment of short-term complexity of heart period variability","authors":"A. Porta, V. Bari, A. Marchi, T. Bassani, P. Castiglioni, M. Di Rienzo, A. Cividjian, L. Quintin","doi":"10.1109/ESGCO.2014.6847492","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847492","url":null,"abstract":"The study compares permutation and coarse-grained entropy approaches for the assessment of short-term complexity of the cardiovascular control from heart period (HP) variability recordings. Approaches were applied to simulations and to HP variability series recorded during complete vagal blockade obtained via administration of a high dose of atropine (AT). Differences between the estimated complexity indexes derived from both simulations and real data indicated that permutation entropy has a larger sensitivity to noise than coarse-grained entropy. We recommend caution in applying permutation entropy in presence of short HP variability series characterized by a low signal-to-noise ratio such as after complete vagal blockade induced by AT.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121798658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiorespiratory coupling functions, synchronization and ageing 心肺耦合功能，同步与衰老
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847579
T. Stankovski, P. McClintock, A. Stefanovska
{"title":"Cardiorespiratory coupling functions, synchronization and ageing","authors":"T. Stankovski, P. McClintock, A. Stefanovska","doi":"10.1109/ESGCO.2014.6847579","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847579","url":null,"abstract":"We discuss the advent of coupling functions as a new dimension in the analysis of cardiorespiratory interactions. By decomposing the separate coupling components in a phase oscillator model, we infer the cardiorespiratory coupling functions with dynamical Bayesian inference for time-evolving and noisy coupled systems. The inferred coupling functions are themselves time-varying processes. On a longer timescale, application to ageing shows that the coupling functions and the direct influence of respiration decrease as age increases. We find that the coupling functions can give rise to synchronization transitions, and that there are no significant changes in synchronization with age.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127255836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Short-term complexity of cardiovascular oscillations during orthostatic change in aging 老年人体位改变过程中心血管振荡的短期复杂性
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847513
A. Catai, A. Takahashi, N. Perseguini, J. Milan, V. Minatel, T. Bassani, V. Bari, A. Marchi, P. R. Santos, A. Borghi-Silva, N. Montano, A. Porta
{"title":"Short-term complexity of cardiovascular oscillations during orthostatic change in aging","authors":"A. Catai, A. Takahashi, N. Perseguini, J. Milan, V. Minatel, T. Bassani, V. Bari, A. Marchi, P. R. Santos, A. Borghi-Silva, N. Montano, A. Porta","doi":"10.1109/ESGCO.2014.6847513","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847513","url":null,"abstract":"Complexity of R-R intervals (RR) and systolic arterial pressure (SAP) variability were computed to detect the aging process influence over cardiovascular control in resting supine (REST) and standing position (STAND). One hundred healthy subjects were divided into five groups (n=20 for each), according to age: 21-30; 31-40; 41-50; 51-60; 61-70. The RR and SAP series were recorded for 15 minutes at REST and STAND. Short sequences of RR and SAP were analyzed by conditional entropy. At REST, RR complexity showed reduction with age in 61-70, and SAP complexity decreased, starting from 31-40. Changes in cardiovascular control complexity, induced by STAND, reveal the difficulty of elderly individuals in dealing with sympathetic stressors.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126002891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of apnea events in sleep breathing disorder by local assessment of the fractal dimension of heart rate 心率分形维数的局部评估对睡眠呼吸障碍患者呼吸暂停事件的表征
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847542
P. Castiglioni, A. Faini, C. Lombardi, M. Di Rienzo, Anna L Ciullo, A. de Felice, G. D'addio
{"title":"Characterization of apnea events in sleep breathing disorder by local assessment of the fractal dimension of heart rate","authors":"P. Castiglioni, A. Faini, C. Lombardi, M. Di Rienzo, Anna L Ciullo, A. de Felice, G. D'addio","doi":"10.1109/ESGCO.2014.6847542","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847542","url":null,"abstract":"Aim of this work is to describe a novel method for estimating overnight modulations of fractal dimension (FD) of R-R intervals (RRI), and to evaluate if these FD estimates may characterize different apnea types in sleep studies. Polysomnographies were performed in 10 patients with severe obstructive sleep apnea syndrome. Both obstructive (OS) and mixed (MX) apneas were found in all patients. The FD of RRI interpolated series was estimated “locally” over a running window of 15 s, overlapped by 14 s, by an algorithm based on the Mandelbrot's definition of the FD of geometric curves. The FD estimator appeared able to follow rapid changes in RRI dynamics. Moreover, it was significantly higher in OS than in MX apneas for 9 out of 10 patients (p<;0.05). Thus, the proposed running FD estimator might enhance the capability of the simplest sleep monitoring devices to characterize sleep breathing disorders.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"679 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116185046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cardio-respiratory interactions in diabetes 糖尿病的心肺相互作用
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847602
L. Bernardi, Milla Rosengard-Barlund, P. Groop
{"title":"Cardio-respiratory interactions in diabetes","authors":"L. Bernardi, Milla Rosengard-Barlund, P. Groop","doi":"10.1109/ESGCO.2014.6847602","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847602","url":null,"abstract":"Alterations in cardiovascular and respiratory reflexes in diabetes are probably one of the first applications of heart rate variability in clinical medicine. Despite significant progress in diabetes care, these abnormalities are still considered the result of anatomical neural damage. Recent research from our group showed that what had been called “neuropathy” is also in part a functional abnormality. This “dysfunction” can be induced by several factors, including tissue hypoxia, hence strictly connected to respiratory abnormalities, but potentially reversible. Therefore, methods aimed at diagnosing these abnormalities in diabetes need to take into account the many possible covariates of heart rate variability, like arterial and tissue oxygenation, the integrated control of breathing and of the cardiovascular system.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122337336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of behavioral activation in non-pathological subjects through Heart Rate Variability monovariate and multivariate multiscale entropy analysis 通过心率变异性单变量和多尺度熵分析表征非病理受试者的行为激活
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847556
M. Nardelli, G. Valenza, I. Cristea, C. Gentili, C. Cotet, D. David, A. Lanatà, E. Scilingo
{"title":"Characterization of behavioral activation in non-pathological subjects through Heart Rate Variability monovariate and multivariate multiscale entropy analysis","authors":"M. Nardelli, G. Valenza, I. Cristea, C. Gentili, C. Cotet, D. David, A. Lanatà, E. Scilingo","doi":"10.1109/ESGCO.2014.6847556","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847556","url":null,"abstract":"The objective quantification of psychological traits through Autonomic Nervous System (ANS) biomarkers is of large interest for the clinical and bioengineering scientific communities. Standard procedures, in fact, rely only on subjective scores from interviews and questionnaires. Here we show that monovariate and multivariate multiscale entropy measures are able to characterize the dimension regulating the behavior towards something pleasant in subjects. Such a psychological dimension was quantified through the BIS/BAS scores and investigated with a complexity analysis of Heart Rate Variability and respiratory activity. Results gathered from 29 volunteers show a significant decrease of multiscale complexity in subjects with higher behavioral activation score during the resting condition, supporting the significant role of ANS nonlinear dynamics in cognitive regulation processes.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122783803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Defining an instantaneous complexity measure for heartbeat dynamics: The inhomogeneous point-process entropy 定义心跳动态的瞬时复杂性度量:非均匀点-过程熵
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847521
G. Valenza, L. Citi, E. Scilingo, R. Barbieri
{"title":"Defining an instantaneous complexity measure for heartbeat dynamics: The inhomogeneous point-process entropy","authors":"G. Valenza, L. Citi, E. Scilingo, R. Barbieri","doi":"10.1109/ESGCO.2014.6847521","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847521","url":null,"abstract":"Complexity measures have been widely used to characterize the nonlinear nature of cardiovascular control and heartbeat dynamics. Current approaches associate these measures to finite single values within an observation window, thus not being able to characterize instantaneous system dynamics. In this study, we introduce the definition of novel measures of entropy based on the inhomogeneous point-process theory and inspired by the approximate and sample entropy algorithms. The discrete heartbeat series are modeled through probability density functions defined at each moment in time, which characterize and predict the next beat occurrence as a function of the past history through Laguerre expansions of the Wiener-Volterra terms. Experimental results, obtained from the analysis of RR interval series extracted from five ECG recordings during postural and tilt-table maneuvers, suggest that the proposed entropy indices can provide instantaneous tracking of the heartbeat complexity and allow for further definition of the “complexity variability” framework.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124681598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantification of ventricular repolarization heterogeneity during moxifloxacin administration using V-index 用v指数定量莫西沙星给药时心室复极异质性
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847580
M. Rivolta, L. Mainardi, R. Sassi
{"title":"Quantification of ventricular repolarization heterogeneity during moxifloxacin administration using V-index","authors":"M. Rivolta, L. Mainardi, R. Sassi","doi":"10.1109/ESGCO.2014.6847580","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847580","url":null,"abstract":"Drug-induced alterations of ventricular heterogeneity must be limited to avoid induction of lethal ventricular arrhythmias. In here, a new parameter called V-index, able to measure the standard deviation of myocites' repolarization times, was evaluated after moxifloxacin administration. 24-h Holter ECGs of 68 healthy subjects enrolled for a thorough QT study were retrospectively analyzed. The placebo and active-comparator (moxifloxacin) arms were considered. The standard QT interval (Fridericia's correction) was included as well, for a direct comparison. V-index and QT increased along with the drug's serum concentration and were statistically different from values in the placebo arm (p<;0.05). Peak values were reached 5 hours after administration (QTc: 428.77 ± 25.17 ms at 5h vs 418.08 ± 23.37 ms at 0h; V-index: 31.67 ± 11.01 ms at 5h vs 27.72 ± 7.59 at 0h) and both were statistically different from predose (p<;0.05). Interestingly, V-index displayed a larger percent variation (27.72% ± 34.06% vs 2.93% ± 2.81%; p<;0.05).","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121375910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effect of biosignal preprocessing and recording length on clinical decision making for cardiac autonomic neuropathy 生物信号预处理和记录长度对心脏自主神经病变临床决策的影响
2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2014-05-25 DOI: 10.1109/ESGCO.2014.6847490
Herbert J Jelinek, T. Alothman, D. Cornforth, K. Khalaf, A. Khandoker
{"title":"Effect of biosignal preprocessing and recording length on clinical decision making for cardiac autonomic neuropathy","authors":"Herbert J Jelinek, T. Alothman, D. Cornforth, K. Khalaf, A. Khandoker","doi":"10.1109/ESGCO.2014.6847490","DOIUrl":"https://doi.org/10.1109/ESGCO.2014.6847490","url":null,"abstract":"Early identification of cardiac autonomic neuropathy (CAN) leads to better treatment outcomes. Heart rate variability (HRV) analysis allows identification of CAN but is sensitive to the length of recording and the presence of artifacts and ectopics, requiring preprocessing and consideration of length of recording. RR intervals from 10-second and 5-minute ECG recordings from patients with no CAN, early CAN and definite CAN were preprocessed using adaptive filtering with the controlling parameter c set at 0.2, 0.5 and 0.8, and time and frequency domain HRV analysis applied. Early CAN and definite CAN required different setting of c with respect to the length of recording. The 5-minute recording with c=0.2 provided the best results using RMSSD for normal versus eCAN (p=0.0007) and for eCAN versus dCAN (0.019). Clinically, this has potential use in general practice for screening patients at risk, newly diagnosed with diabetes, or for follow-up during the course of diabetes.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131563910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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