{"title":"Psychodynamic Psychotherapy for Obsessive-Compulsive Disorder: A Single-Case Report with Quantified Outcomes.","authors":"Paolo Mandolillo, Vincenzo Maria Romeo","doi":"10.1521/pdps.2026.54.3.496","DOIUrl":"10.1521/pdps.2026.54.3.496","url":null,"abstract":"<p><p>Obsessive-compulsive disorder (OCD) remains a disabling condition for a subset of patients who fail to respond to first-line behavioral protocols. We report a measurement-informed psychodynamic psychotherapy case of an adult with <i>DSM-5</i> OCD characterized by harm- and contamination-related intrusions with checking/washing rituals. The patient received psychodynamic treatment using clarification, confrontation, and interpretation, focused on defenses of isolation of affect, undoing, and intellectualization. Outcomes were tracked with gold-standard metrics. Obsessive-compulsive severity improved from Y-BOCS 26 (baseline) to 16 (posttreatment) (Δ = 10; -38.5%), meeting conventional response thresholds; GAF rose from 58 to 70 (Δ = +12). Dimensional burden (DOCS) decreased from 56 at baseline to 41 at a 24-month delayed follow-up, suggesting durability. No adverse events occurred. This case illustrates how psychodynamic psychotherapy for OCD could be paired with systematic outcome monitoring. Observed mechanisms of change include increased affect tolerance, reduced reliance on isolation/undoing, and enhanced capacity to mentalize conflict-laden meanings, with reductions in ritualizing and avoidance. Larger multicenter cohorts and manualized treatment trials are warranted to define effectiveness and mechanisms of change relative to exposure-based and combined integrative approaches.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"496-510"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding the Psychology, Genetics, and Neurobiology of Happiness with Clinical Implications.","authors":"Ahron Friedberg, Sandra Sherman","doi":"10.1521/pdps.2026.54.3.476","DOIUrl":"10.1521/pdps.2026.54.3.476","url":null,"abstract":"<p><p>This article examines contested definitions of happiness, ranging from Freudian notions of unalloyed pleasure to more expansive ideas of satisfaction and contentment. More particularly, it considers how these approaches are interpreted through the specific disciplinary lenses of psychology, neurobiology, and genetics. It shows how, within each, there are disputes and areas of uncertainty, and it delineates the clinical implications of these approaches' largely siloed research agendas. By way of advancing such research agendas, it explores possibilities for how these approaches may, in combination, contribute to raising an individual's \"set-point\" of happiness, permitting greater life satisfaction notwithstanding trauma and disappointment. In this regard, it examines the psychological and physiological bases of resilience, as well as everyday activities that promote happiness. It highlights recent research demonstrating that happiness increases an individual's health and longevity. Finally, it looks at how psychodynamic psychiatrists can integrate an understanding of happiness into their practices, thereby increasing patients' ability to develop habits that promote happiness.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"476-495"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updating Psychotherapy Work with the Future: Futures Thinking and the Futurizing Functions of Containment.","authors":"Janet L Lewis, Elizabeth Haase","doi":"10.1521/pdps.2026.54.3.403","DOIUrl":"https://doi.org/10.1521/pdps.2026.54.3.403","url":null,"abstract":"<p><p>The acceleration of climate change and other global and political crises has created a state of \"permacrisis,\" confronting patients with significant distress about and need to grapple with complex and threatening futures emerging from ecological and social upheaval. A core task of psychotherapy has always been imagining alternative paths and self-definitions to improve future outcomes, formalized in approaches such as \"future-oriented therapy\" or \"future-directed therapy.\" Now the neurobiological and psychological mechanisms that support the process of thinking about potential futures are better understood. We review the neuropsychiatric basis of the human ability to think about the future and how the evolving field of Futures Thinking/Futures Literacy can be used in psychodynamic treatment to support patients' adaptation to increasing climate and global threats. Describing the four existing modes of Futures Thinking (quantitative forecasting, practicing with futures, experiments of social cocreation, and critical deconstruction of futures), we posit use of the psychodynamically understood process of containment as a fifth mode, essential in strengthening all modes of futures work by allowing individuals to generatively hold difficult or catastrophic possibilities. Applying the work of Bion, Winnicott, and Green, we describe the essential relationship of containment to experiential, emotional, psychological, and neurodevelopmental processes that undergird psychic understandings of time, identity consolidation, and future imagination. Containment has a \"futurizing\" function embedded within it, which is the creation of hope. The appreciation of containment's central role in engaging potential futures clarifies the therapeutic stance in a time of \"permacrisis.\"</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"403-427"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Distinguishing Mood Temperaments from Personality Disorders: Diagnostic and Clinical Implications.","authors":"Mark L Ruffalo, Alex M Ray","doi":"10.1521/pdps.2026.54.3.381","DOIUrl":"https://doi.org/10.1521/pdps.2026.54.3.381","url":null,"abstract":"<p><p>Temperament refers to enduring, biologically rooted affective dispositions that influence how individuals experience and regulate emotion. Although central to classical psychiatry, from Kraepelin's manic-depressive illness to Akiskal's affective styles, temperaments have been largely excluded from modern nosology and psychoanalytic theory. This omission has contributed to diagnostic confusion, particularly in differentiating cyclothymic temperament from borderline personality disorder and hyperthymic temperament from narcissistic personality disorder. While these conditions share surface similarities, they diverge in etiology, structure, and treatment. Cyclothymia reflects subsyndromal, endogenous mood fluctuations, whereas borderline personality disorder involves identity disturbance, interpersonal hypersensitivity, and reliance on primitive defenses. Hyperthymia is characterized by persistent high energy, optimism, and risk-taking, while narcissistic personality disorder reflects structural personality pathology, defensive grandiosity, and vulnerabilities in self-esteem regulation. Clarifying these distinctions is essential for improving diagnostic accuracy, guiding treatment, and fostering dialogue between biological psychiatry and psychoanalysis.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"381-388"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Albert Schweitzer: A Reverence for Life, Empathy, and the Medical Vocation.","authors":"Eugenio M Rothe","doi":"10.1521/pdps.2026.54.3.389","DOIUrl":"https://doi.org/10.1521/pdps.2026.54.3.389","url":null,"abstract":"<p><p>Albert Schweitzer's life integrated theology, philosophy, music, and medicine into a unified ethical commitment to humanity. Awarded the 1952 Nobel Peace Prize, he articulated a moral vision grounded in deep empathy and respect for all living beings. This article examines the developmental, relational, and cultural influences that shaped his life trajectory, including his upbringing in Alsace, formative experiences of privilege and moral sensitivity, and the intellectual impact of philosophical and religious traditions. It traces his transition from a distinguished academic career to the pursuit of medicine and his lifelong humanitarian work in Gabon. Attention is given to the emergence of his ethical framework and its expression through clinical service. Drawing on concepts of narrative identity and generativity, the article situates Schweitzer's life within a redemptive narrative that continues to inform contemporary understandings of the medical vocation. His legacy offers an enduring model for integrating empathy, ethical responsibility, and meaning in clinical practice.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"389-402"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Gazzillo, David Kealy, Camilla Mannocchi, Marshall Bush
{"title":"Guilt over \"Having a Life\": Understanding and Addressing Separation/Disloyalty Guilt.","authors":"Francesco Gazzillo, David Kealy, Camilla Mannocchi, Marshall Bush","doi":"10.1521/pdps.2026.54.3.442","DOIUrl":"10.1521/pdps.2026.54.3.442","url":null,"abstract":"<p><p>This article aims to offer an overview of our knowledge about separation/disloyalty guilt, a maladaptive kind of interpersonal guilt that derives from pathogenic beliefs that associate the healthy and adaptive goals of being separate, different, and independent from important others with the danger of deeply hurting them. These pathogenic beliefs stem from early relational traumas and adverse experiences, such as having had relatives who showed their children that they were visibly hurt by the attempts at exploration and differentiation from their children. Separation/disloyalty guilt has been shown to correlate with eating disorders, panic disorders, obsessive and phobic disorders, illness anxiety disorder, and with transdiagnostic features such as difficulties in mentalization, emotion regulation, and intolerance to frustration. We describe how patients with separation/disloyalty guilt can look for disconfirmations of these pathogenic beliefs during their psychotherapies and how clinicians can help them have the corrective emotional experiences they need.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"442-461"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic Relationship: A Factor for Substantial Change in Psychodynamic Psychotherapies and Psychoanalysis.","authors":"Milton Viederman","doi":"10.1521/pdps.2026.54.3.462","DOIUrl":"10.1521/pdps.2026.54.3.462","url":null,"abstract":"<p><p>Significant change in psychodynamic psychotherapy resides in the uncovering of unconscious conflicts as they manifest themselves in the lives of patients. My intent in this article is to illustrate the special power of the therapeutic relationship as a separate element beyond interpretation as a vehicle for a change. This is illustrated by three patients who revealed special feelings of affection for me in the context of our work together and the progress that they had made. The substrate of these feelings is a product of a consistent acceptance and valuation of the patient in all that they reveal. These are aspects of the real relationship and are not the distortions of transference projections, although they may evoke elements of an ideal parent.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"462-475"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examining Who Benefits from Short-Term Psychodynamic Psychotherapy for Depression: Insights from a Series of Individual Participant Data Meta-analyses.","authors":"Frederik J Wienicke, Ellen Driessen","doi":"10.1521/pdps.2026.54.3.373","DOIUrl":"10.1521/pdps.2026.54.3.373","url":null,"abstract":"<p><p>Because little was known about who benefits specifically from short-term psychodynamic psychotherapy (STPP) for depression, we conducted an individual participant data meta-analysis project, collecting and combining raw datasets from 43 trials (N = 4,155) assessing its efficacy and examining participant baseline characteristics as moderators of outcome. Findings supported STPP's efficacy compared to control conditions and antidepressant medication, and when added to antidepressants. Episode duration and baseline severity moderated treatment outcome. Drawing on these findings and a decade of data collection experiences for this project, we outline seven recommendations for future research to further strengthen the field. The collective individual participant data meta-analysis database is available for use by others, pending original investigators' approval. Information on how it can be accessed is provided. Through continued collaboration, we hope to increase the scope of STPP research and contribute to a more precise understanding of which patients benefit most from this frequently used treatment.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"373-380"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephan Doering, Frank Yeomans, Philipp Martius, Eve Caligor, Mathias Lohmer, Agnes Schneider-Heine, Nel Draijer, Luis Valenciano, Otto Kernberg
{"title":"Supervision in Transference-Focused Psychotherapy.","authors":"Stephan Doering, Frank Yeomans, Philipp Martius, Eve Caligor, Mathias Lohmer, Agnes Schneider-Heine, Nel Draijer, Luis Valenciano, Otto Kernberg","doi":"10.1521/pdps.2026.54.3.428","DOIUrl":"https://doi.org/10.1521/pdps.2026.54.3.428","url":null,"abstract":"<p><p>Transference-focused psychotherapy is a modified psychoanalytic psychotherapy for patients with borderline personality disorder as well as patients with impaired personality functioning. Supervision of candidates and psychotherapists is regarded as mandatory and employs video recording of all sessions. The supervisor's task is to be aware of the patient's external reality as well as of the treatment frame. Only after the setting is protected in this way, the treatment process is focused with an emphasis on the therapeutic relationship (transference) in the here-and-now. The parallel process (relational patterns from the treatment that repeat within the supervisory process) is used to understand the treatment process and to create an affective experience as well as cognitive understanding within the supervisee.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"428-441"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomas Lindegaard, Matilda Berg, Anton Käll, Julia Lockman, Edvin Schönberg, Martin Björklund, Ronald J Frederick, Gerhard Andersson
{"title":"Internet-Delivered Affect Phobia Therapy for Neuroticism: Results from an Uncontrolled Pilot Study with 6-Month Follow-Up.","authors":"Tomas Lindegaard, Matilda Berg, Anton Käll, Julia Lockman, Edvin Schönberg, Martin Björklund, Ronald J Frederick, Gerhard Andersson","doi":"10.1521/pdps.2026.54.3.511","DOIUrl":"https://doi.org/10.1521/pdps.2026.54.3.511","url":null,"abstract":"<p><p><b>Objective:</b> Trait neuroticism both correlates with and predicts mental and physical health outcomes and has been characterized as a transdiagnostic risk factor for mental health problems. No previous studies have investigated if internet-delivered psychodynamic therapy (IPDT) can reduce levels of neuroticism. The aim of the present study was to investigate the preliminary effect of affect-focused IPDT on trait neuroticism in a sample with mixed anxiety and depressive symptoms. <b>Methods:</b> In total, 30 participants were included and assigned to 10 weeks of therapist-supported IPDT. Self-reported levels of neuroticism measured with the IPIP-NEO 300 were used as the primary outcome measure. Secondary measures of depression, anxiety, quality of life, neuroticism, treatment satisfaction, emotion regulation, and defense mechanism adaptiveness were also included. <b>Results:</b> Levels of neuroticism were significantly reduced following the intervention, Cohen's <i>d</i> = 0.64, [.19, 1.1], and these reductions were maintained at the 6-month follow-up. Significant effects were also found across the secondary outcome measures. Changes in defense mechanism adaptiveness significantly predicted changes in neuroticism, β <i>=</i>.63. <b>Discussion:</b> The results indicate that affect-focused IPDT shows promise in reducing trait neuroticism and that changes in defense mechanism adaptiveness may account for a substantial part of the observed effect. These results need to be replicated using a randomized controlled trial design.</p>","PeriodicalId":38518,"journal":{"name":"Psychodynamic Psychiatry","volume":"54 3","pages":"511-531"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}