Swiss dental journal最新文献_第8页

Inflammatory stimulation of osteoblasts and keratinocytes from a SAPHO patient for implant risk evaluation. 对一名 SAPHO 患者的成骨细胞和角质细胞进行炎症刺激，以评估植入风险。

Swiss dental journal Pub Date : 2023-05-15 Epub Date: 2023-01-10 DOI: 10.61872/sdj-2023-05-01

Patrick R Schmidlin, Liza L Ramenzoni

{"title":"Inflammatory stimulation of osteoblasts and keratinocytes from a SAPHO patient for implant risk evaluation.","authors":"Patrick R Schmidlin, Liza L Ramenzoni","doi":"10.61872/sdj-2023-05-01","DOIUrl":"10.61872/sdj-2023-05-01","url":null,"abstract":"The present report exemplifies a translational method, which could assist the clinical preevaluation of patients at risk before surgical interventions. In this study, a presurgical implant decision in a case of SAPHO (synovitis, acne, palmoplantar pustulosis, hyperostosis, osteitis) is described. Since the etiology of this syndrome is likely to involve genetic, infectious and immunological components, lipopolysaccharides (LPS) may conceptually trigger cytokine production leading to a specific chronic inflammation and immunological host response. This may hamper proper healing or accentuate the destruction of periodontal host tissues. In our approach, we examined the ex vivo cell viability and immune responses of primary osteoblasts and keratinocytes under sterile inflammation induced by P. gingivalis LPS. Keratinocytes and osteoblasts were obtained from biopsies of the keratinized gingiva and alveolar bone tissues of a SAPHO human subject. Enzymatically dissociated cells were thus cultured and incubated to LPS at different concentrations (50ng/ml, 200ng/ml, 500ng/ml and 1μg/ml) for 24 h in order to test inflammatory cytokine response (quantitative real time PCR) and toxicity (cell viability). Healthy primary keratinocytes and osteoblasts were used as control cells. The highest concentration of LPS (1μg/ml) significantly reduced cell viability (p < 0.05). Meanwhile, all tested LPS concentrations similarly enhanced the mRNA expressions of selected inflammatory cytokines (TNFα, IL-6, IL-8, IL-1β and IL-1𝛼) up to ≈3.5-fold, when compared to the healthy cell controls (p < 0.05). This study demonstrated a valuable inflammatory risk evaluation before implant placement, which was successfully performed based on the presented laboratory diagnostic/prognostic approach.Sapho.","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"133 5","pages":"297-303"},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9482246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intensive oral hygiene programme for the diagnosis and (pre-)treatment of gingival mucosal redness and swelling 用于诊断和（预）治疗牙龈红肿的强化口腔卫生方案。

Swiss dental journal Pub Date : 2023-05-15 DOI: 10.61872/sdj-2023-05-02

Patrick R Schmidlin, Milena Mendolera

引用次数: 0

Meeting Quality Metrics in Oral Squamous Cell Carcinoma Surgery: A Single-Center Experience. 满足口腔鳞状细胞癌手术质量指标：单中心经验。

Swiss dental journal Pub Date : 2023-04-03 Epub Date: 2022-12-15 DOI: 10.61872/sdj-2023-04-01

Daphne Schönegg, Michèle Suter, Danielle Kundert, Thomas Gander, Martin Lanzer

{"title":"Meeting Quality Metrics in Oral Squamous Cell Carcinoma Surgery: A Single-Center Experience.","authors":"Daphne Schönegg, Michèle Suter, Danielle Kundert, Thomas Gander, Martin Lanzer","doi":"10.61872/sdj-2023-04-01","DOIUrl":"10.61872/sdj-2023-04-01","url":null,"abstract":"Patient-centered quality metrics have been proposed to evaluate and optimize hospital processes, aiming to improve patient outcomes. Furthermore, they can be used to objectively rate and compare the ability of health care providers to meet the needs of their patients. In patients with advanced resectable oral squamous cell carcinoma, optimal surgical treatment of the neck and timely initiation of both surgical and adjuvant therapy, when indicated, are crucial for recurrence-free and overall survival. This retrospective analysis included 160 patients who received primary resection of oral squamous cell carcinoma and concurrent neck dissection. It aimed to investigate how well quality metrics were met during a 6-year period in the department of oral and maxillofacial surgery at a university hospital. 93.1% of patients were seen in the specialist's office within 21 days after referral. Resection was classified as R0 in 94.4%. A lymph node yield ≥ 18 was achieved in 82.5%. The lymph node ratio was ≤6% in 43.3% of nodal-positive necks. Readmission and unplanned revision surgery were rare (6.9%). Adjuvant radiotherapy was started ≤ 6 weeks after surgery in 45.3%, and the indication was in accordance with international guidelines in all cases. \u0000Quality metrics are an effective tool for planning process optimization in a hospital. Moreover, nodal quality metrics such as lymph node yield and lymph node ratio could, after validation, complement existing and well-established prognostic parameters for patient-specific adaptation of adjuvant treatment plans.","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"133 4","pages":"230-235"},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9166507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Melkersson-Rosenthal syndrome - a diagnostic-therapeutic challenge in oral medicine 梅尔科森-罗森塔尔综合征--口腔医学诊断治疗的挑战。

Swiss dental journal Pub Date : 2023-04-03 DOI: 10.61872/sdj-2023-04-02

Michael M Bornstein, Daniel Baumhoer, Alexander A Navarini

引用次数: 0

Evaluation of antibacterial properties of fluoride-containing mouth rinses differing in their acidic compound using a Streptococcus mutans biofilm. 利用变异链球菌生物膜评估不同酸性化合物含氟漱口水的抗菌性能。

Swiss dental journal Pub Date : 2023-03-06 Epub Date: 2022-11-24 DOI: 10.61872/sdj-2023-03-01

Sally Koegel, Olivier Braissant, Tuomas Waltimo, Michael M Bornstein, Monika Astasov-Frauenhoffer

{"title":"Evaluation of antibacterial properties of fluoride-containing mouth rinses differing in their acidic compound using a Streptococcus mutans biofilm.","authors":"Sally Koegel, Olivier Braissant, Tuomas Waltimo, Michael M Bornstein, Monika Astasov-Frauenhoffer","doi":"10.61872/sdj-2023-03-01","DOIUrl":"10.61872/sdj-2023-03-01","url":null,"abstract":"This in vitro study assessed the antibacterial effect on Streptococcus mutans biofilms of mouth rinses with 700 ppm F- (derived from NaF) that differed only in their acid compounds (malic (A), citric (B), tartaric (C), fumaric (D), hydrochloric (E), phosphoric (F), and lactic (G) acid) used to adjust pH. S. mutans (ATCC 25175) was grown for 22 h at 37°C, harvested, resuspended in simulated body fluid and biofilm formation followed for 24 h at 37°C. Thereafter, biofilms were treated with experimental rinses for 30 s, and placed in TAM48 isothermal microcalorimeter at 37°C for 72 h. Applying Gompertz growth model parameters lag time and growth rate were determined from heatflow curves; additionally, reduction of active biofilms was calculated. Moreover, samples were live/dead stained and analyzed by confocal scanning microscopy. All mouth rinses were showing statistically significant lag time and reduction of active biofilm (p<0.05, A 19.1+/-2.3h and 58.5+/-7.7%, B 15.5+/-1.1h and 41.9+/-5.3%, C 17.6+/-1.9h and 53.1+/-7.5%, D 18.4+/-2.4h and 55.8+/-8.8%, E 20.2+/-3.3h and 61.5+/-10.0%, F 20.2+/-3.0h and 61.6+/-9.3%, and G 18.3+/-2.5h and 55.3+/-8.9%). Interestingly, there were no differences found between the treated groups (p>0.05, A 0.064+/-0.004 1/h, B 0.063+/-0.005 1/h, C 0.065+/-0.004 1/h, D 0.067+/-0.004 1/h, E 0.066+/-0.006 1/h, F 0.067+/-0.004 1/h, G 0.066+/-0.006 1/h) for the maximum growth rate. Vitality staining supported these findings.. The present investigation demonstrates that the type of acid compounds used to produce the rinses did not show any negative effect on the antimicrobial properties of the tested products as all of them exhibited a similar efficacy against S. mutans biofilms.","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"133 ","pages":"156-163"},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40509558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Aesthetic rehabilitation of a case of maxillary fibrous dysplasia in a child]. [一例儿童上颌纤维发育不良的美学康复治疗]。

Swiss dental journal Pub Date : 2023-03-06 DOI: 10.61872/sdj-2023-03-02

Elise Pilavyan, Delphine Wagner, François Clauss, Marion Strub

引用次数: 0

Interceptive orthodontics - Treatment of distal bite, non-supports 阻断性正畸--治疗远端咬合、不对齐。

Swiss dental journal Pub Date : 2023-03-06 DOI: 10.61872/sdj-2023-03-03

René Kubala, Roger Minoretti

引用次数: 0

[Extrusion after anterior tooth trauma - Magnet and Benexextrusion, two case presentations] 前部创伤后的挤压：磁性挤压和 Benex 挤压，两个病例介绍。

Swiss dental journal Pub Date : 2023-02-06 DOI: 10.61872/sdj-2023-02-03

Kevin Hofpeter, Sebastian Reich, Alexander Winkler, Gabriel Krastl

引用次数: 0

[Intraoral radiography: qualitative study]. [口内放射摄影：定性研究]。

Swiss dental journal Pub Date : 2023-02-06 DOI: 10.61872/sdj-2023-02-02

Sarah Freyche, Lydia Vazquez

{"title":"[Intraoral radiography: qualitative study].","authors":"Sarah Freyche, Lydia Vazquez","doi":"10.61872/sdj-2023-02-02","DOIUrl":"10.61872/sdj-2023-02-02","url":null,"abstract":"When taking intraoral X-rays with a round collimator, the salivary glands and the thyroid gland are exposed to ionizing radiation. The rectangular collimator reduces the patient's radiation dose. This study aims to analyze the impact of the rectangular collimator on the quality of intraoral X-rays taken by students of the University Clinics of Dental Medicine (Geneva, Switzerland). Intraoral X-rays, performed by 8 students with digital intraoral phosphor plates, were collected and a quality score was assigned to each X-ray. A total of 130 intraoral radiographs were analyzed. Half of the radiographs were taken with a rectangular collimator and 24.6% (32/130) were bitewings. The mean quality score of bitewings taken with or without a collimator was 11 ± 1.8 and 10.3 ± 0.9, respectively. The mean quality score of apical X-rays taken with or without collimator was 11.6 ± 1.0 and 11.5 ± 2.1, respectively. X-rays taken with a rectangular collimator were of excellent or sufficient diagnostic quality for 95% of the bitewings and 100% of the periapical radiographs. This quality control study showing that students perform quality intraoral X-rays with a rectangular collimator could encourage clinicians to use this device as ameans of radiation protection in their daily practice.","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"133 2","pages":"89-96"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10632750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-reported injuries to oral tissues through resistance training in bodybuilders. 健美运动员通过阻力训练对口腔组织造成伤害的自我报告。

Swiss dental journal Pub Date : 2023-02-06 Epub Date: 2022-10-14 DOI: 10.61872/sdj-2023-02-01

Nira Maria Wangoi Mählmann, Andreas Filippi

{"title":"Self-reported injuries to oral tissues through resistance training in bodybuilders.","authors":"Nira Maria Wangoi Mählmann, Andreas Filippi","doi":"10.61872/sdj-2023-02-01","DOIUrl":"10.61872/sdj-2023-02-01","url":null,"abstract":"Lifting heavy weights almost automatically elicits teeth clenching, which, if performed regularly, may lead to chronic trauma. This study assessed self-reported injuries to oral tissues in athletes and bodybuilders caused by resistance training and determined the association between self-reported trauma, performance level and the duration of practicing resistance training. A standardized questionnaire was used to gather information about the respondents (age and gender), their performance level (hobby versus competition athlete), experience with oral tissue trauma, the use of mouthguards, and dietary habits. From a total of 363 females and 239 males, 221 (36.7%) classified themselves as competition athletes and 381 (63.3%) as hobby athletes. Nearly 34.6% (n = 202) of the participants declared distress in their orofacial region during practice. Female hobby athletes reported 2.5 times more mouth-teeth-jaw problems than female competition athletes (p < 0.001). Females showed themselves slightly more susceptible to mouth-teeth-jaw problems with resistance training than males (odds ratio [OR] = 1.45, p = 0.076). Negative oral effects were found to be 2.1 (p = 0.003) times higher for those who had been practicing for 10 years or more. It was concluded that a higher number of years of resistance training increased self-reported oral tissue trauma in the current cohort. Females were more likely to report orofacial problems than males.","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"133 2","pages":"80-87"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10630158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0