{"title":"On the biocompatibility of endodontic sealers.","authors":"Vasileios Kapralos, Jannis Böcker, Kirstin Vach, Markus Altenburger, Susanne Proksch, Lamprini Karygianni","doi":"10.61872/sdj-2022-09-01","DOIUrl":"https://doi.org/10.61872/sdj-2022-09-01","url":null,"abstract":"<p><p>Periapical tissue may be exposed to root canal filling materials in consequence of root canal therapy. There is scant scientific data about the biocompatibility of root canal filling materials of various chemistry on the periapical area. This study aimed to investigate the effects of different root canal sealers and their eluates on human alveolar osteoblasts in terms of cell proliferation, adhesion, morphology and gene expression in vitro. Five endodontic sealers (AH Plus®, Apexit®, Tubli-Seal®, Real Seal SE®, EndoRez®) and one gutta-percha obturation material (BeeFill®) were tested. Human alveolar osteoblasts derived from 3 different donors following incubation with sealer eluates after 24 h and 72 h were investigated by means of qPCR (gene expression). Morphological reactions of the alveolar osteoblasts were measured by culturing the cells for 3 d, and 7 d and 14 d, respectively, followed by scanning electron microscopy (morphology, adhesion) and fluorescence imaging of the actin cytoskeleton (morphology, proliferation). A repeated measures analysis was performed and p-values were adjusted by Tukey. While all sealers influenced the cell morphology and the expression of genes associated with apoptosis (Casp3), proliferation (histone H3), and inflammation (interleukin-6 and matrix metalloproteinases 1 and 3), mainly AH Plus® and Apexit® yielded a regular actin cytoskeleton and beneficial gene expression patterns. Regarding cell adhesion, only AH Plus® supported proper anchorage for alveolar osteoblasts. Our results provide evidence for the biocompatibility of epoxy resin-based endodontic sealers, i.e. AH Plus®, while other sealers proved cytotoxic for alveolar osteoblasts. Further studies are needed for understanding the bone cell reactions after endodontic treatment and the clinical decision-making regarding the sealer of choice for root canal fillings.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"132 9","pages":"586-597"},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astrid Toferer, Larissa Sampl, Wolfgang Zemann, Philipp Metzler
{"title":"[Local anesthetics with elderly patients].","authors":"Astrid Toferer, Larissa Sampl, Wolfgang Zemann, Philipp Metzler","doi":"10.61872/sdj-2022-09-03","DOIUrl":"10.61872/sdj-2022-09-03","url":null,"abstract":"<p><p>When choosing local anesthetics, risk factors such as underlying diseases, use of other medications and allergies have to be taken into consideration. Systematic complications might occur if a specific limit in the plasma concentration is exceeded. Articaine and prilocaine are metabolized extrahepatically. In case of an absolute contraindication for vasoconstrictors, the use of mepivacaine, bupivacaine or articaine is recommended.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":" ","pages":"614-615"},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40344165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe Biel, Thomas Biel, Vivianne Chappuis, Clemens Raabe
{"title":"[Re-osseointegration of a Dental Implant with Aseptic Loosening after Occlusal Correction: a Case Report].","authors":"Philippe Biel, Thomas Biel, Vivianne Chappuis, Clemens Raabe","doi":"10.61872/sdj-2022-09-02","DOIUrl":"10.61872/sdj-2022-09-02","url":null,"abstract":"<p><p>The preservation of osseointegration is fundamental for the long-term success of dental implants. Breakdown of osseointegration may occur in cases of aseptic implant loosening, a poorly understood process leading to sudden implant failure. So far, no evidence-based therapy concept exists for implants with aseptic loosening. The present case report demonstrates the re-osseointegration of a dental implant in the mandible of a 79-year-old female patient with mamma carcinoma after loss of osseointegration caused by aseptic loosening. The only treatment performed was a correction of the occlusion. After a period of eight months, a re-osseointegration was observed clinically and radiographically, and remained stable for the follow-up period of 21 months. Reduction of occlusal forces after correction of the occlusion may have facilitated a re-osseointegration. Potential influences of concurrent antineoplastic chemotherapy regarding breast carcinoma or further unknown influences on implant re-osseointegration cannot be ruled out.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":" ","pages":"599-606"},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40344162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swiss dental journalPub Date : 2022-07-11Epub Date: 2022-04-28DOI: 10.61872/sdj-2022-07-08-01
Nader Saadeddin, Manar Ali Al-Khalil, Omar Al-Adel
{"title":"Effect of immediate dentin sealing on the fracture strength of lithium disilicate ceramic onlays.","authors":"Nader Saadeddin, Manar Ali Al-Khalil, Omar Al-Adel","doi":"10.61872/sdj-2022-07-08-01","DOIUrl":"https://doi.org/10.61872/sdj-2022-07-08-01","url":null,"abstract":"<p><p>This study aimed to evaluate the effect of immediate dentin sealing (IDS) on the fracture strength of ceramic onlays when compared with delayed dentin sealing (DDS). Twenty extracted human maxillary premolars were randomly divided into 2 groups according to the dentin sealing technique (n=10). A standardized mesio-occlusal-distal cavity was prepared with reduction of the palatal cusp. The dentin surfaces of the IDS group were immediately sealed after finishing the preparation (before taking impressions, temporization, and 14-day storage at 37°C) using a bonding system (ALL-BOND 3®, ALL-BOND 3® RESIN) and flowable composite (Te-Econom Flow). Impressions were made and temporary restorations were fabricated using PRO-V FILL®. The wax patterns were milled and the onlays were fabricated by heat-pressing technique (IPS e.max Press). After bonding the final restorations with resin cement (Variolink N), the specimens were thermocycled. Fracture strength was measured using a universal testing machine (Testometric M350-10KN) at 1 mm/min until failure occurred. Student's t-test was used to evaluate the results of the fracture strength test. The failure mode was examined using a stereomicroscope. The mean fracture strength in the IDS group (1335 ± 335 N) was statistically significantly higher than that for the DDS group (931 ± 274 N) (p < 0.05). Fracture of the restoration with a small portion of the tooth was the most frequent mode of failure. Within the limitation of this in vitro study, there was an improvement in the fracture strength of ceramic onlays with the use of IDS. However, the ceramic onlays were strong enough to withstand the physiological mastication force in both groups.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"132 7-8","pages":"482-489"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina Schriber, Martin Lanzer, Thomas Gander, Michael M Bornstein
{"title":"Central giant cell granuloma in the mandible. Therapy in a 13-year-old patient with denosumab","authors":"Martina Schriber, Martin Lanzer, Thomas Gander, Michael M Bornstein","doi":"10.61872/sdj-2022-07-08-04","DOIUrl":"10.61872/sdj-2022-07-08-04","url":null,"abstract":"<p><p>Central giant cell granuloma (CGG) is a benign intraosseous osteolytic jaw lesion that accounts for approx. 7% of all benign jaw tumours. Inflammatory, infectious or neoplastic processes are cited as the cause of ZRZG, with genetic components also playing a role. Children or young adults before the age of 30 and women are typically affected.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":" ","pages":"512-513"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40586951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swiss dental journalPub Date : 2022-07-11Epub Date: 2022-04-26DOI: 10.61872/sdj-2022-07-08-02
Prem K Sreenivasan, Bhojraj Nandlal, Ganganna Aruna, S Madhunapantula, Andrew J McBain
{"title":"The Utility of Salivary Heme to Stratify Healthy Volunteers from Individuals with Gingivitis and Periodontitis: a Pilot Study.","authors":"Prem K Sreenivasan, Bhojraj Nandlal, Ganganna Aruna, S Madhunapantula, Andrew J McBain","doi":"10.61872/sdj-2022-07-08-02","DOIUrl":"https://doi.org/10.61872/sdj-2022-07-08-02","url":null,"abstract":"<p><p>Gingival bleeding due to poor oral hygiene is reported globally. Assessment of blood in saliva may improve diagnostics, serve as an outcome measure in clinical trials and support patient education through point-of-care tests. This work analyzed salivary heme using a rapid test format and separately using a lateral flow immunoassay assay [LF] for chair-side implementation. Clinical examinations stratified adult subjects into healthy, gingivitis or periodontitis groups at baseline. Healthy subjects presented no periodontal pockets and whole mouth gingivitis scores of less than 1.0. Gingivitis subjects registered gingival index scores greater than 1.0. Included in the periodontal disease group were subjects with periodontal pockets greater than 4 mm. The rapid test is based on the peroxidase activity salivary heme converting a colourless probe to a coloured compound for spectrophotometric analysis. For the LF assay, saliva was placed in the test window of the device with reactions scored after room temperature incubation. Average salivary heme concentrations in the healthy, gingivitis and periodontal disease groups were 27, 201 and 326 nM respectively, by the rapid test, representing significant differences by analysis of variance and Tukey's-multiple comparison tests (p<0.05). Similarly, results in the LF assay demonstrated increasing band intensity from the healthy to the periodontal disease groups and was quantifiable by image analysis. This pilot study emphasizes the potential efficacy of rapid heme measurement in investigations of oral health.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"132 7-8","pages":"490-497"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The perenity of the indirect bonded restorations : the «no-finishing concept»].","authors":"David Gerdolle, Stéphane Browet, Marco Gresnigt","doi":"10.61872/sdj-2022-07-08-03","DOIUrl":"10.61872/sdj-2022-07-08-03","url":null,"abstract":"<p><p>Over the past 30 years, the development of adhesive techniques has reduced the biological cost of bonded indirect restorations (in/onlays and veneers). However, the procedures for bonding to dental tissue are still more demanding than those for conventional cemented prostheses. One of the keys to the durability of indirect adhesive restorations is their ability to prevent bacterial plaque from adhering to their surface. With this in mind, this article describes a clinical protocol for obtaining the smoothest possible prosthetic margins, without resorting to conventional finishing and polishing techniques, which are tedious and time-consuming.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":" ","pages":"499-504"},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40565547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Swiss dental studies in comparison. A data collection of the Swiss graduating classes from the years 2015-2018 compared to the EU].","authors":"Pascal Zeller, Oliver Zeyer, Urs Brägger","doi":"10.61872/sdj-2022-06-02","DOIUrl":"10.61872/sdj-2022-06-02","url":null,"abstract":"<p><p>The aim of this publication is to draw a comparison between dental studies in the EU and in Switzerland. For this purpose, Swiss students from the graduation years 2015-2018 were surveyed about their practical training. These results could be compared with figures from the EU. Of the 34 treatments compared, 26 were performed more often by Swiss students. In addition to the comparison with the EU area, it was also possible to determine that over two-thirds of the students felt well-prepared for the world of work. However, the students wished for more in-depth training in the areas of fixed prosthetics as well as surgery.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"312 6","pages":"415-422"},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swiss dental journalPub Date : 2022-06-13Epub Date: 2022-04-14DOI: 10.61872/sdj-2022-06-01
Anna Jenner, Christoph A Ramseier
{"title":"Impact of a single information session with oral hygiene instructions on unaccompanied minor asylum seekers living in Switzerland.","authors":"Anna Jenner, Christoph A Ramseier","doi":"10.61872/sdj-2022-06-01","DOIUrl":"https://doi.org/10.61872/sdj-2022-06-01","url":null,"abstract":"<p><p>Asylum-seeking adolescents who have passed the age of mandatory schooling may not have had the opportunity to receive oral hygiene instructions (OHI) similar to Swiss adolescents. Therefore, the aim of this study was to evaluate the impact of a single information session with OHI on both the knowledge about the consequences of lacking oral hygiene and the likelihood of implementing these instructions in unaccompanied adolescent asylum seekers living in Switzerland. Before and after a single information session with OHI, adolescent asylum seekers in two asylum centres (Menziken and Suhr, AG) were surveyed with written questionnaires. During the event, the consequences of lacking oral hygiene on oral health were explained and the Bass brushing technique was instructed and practised. The present analysis included 30 male asylum seekers aged 15-18. In total, 90% (n=27) cleaned their teeth daily and 70% (n=13) had received previous OHI at their school (19.1%) or a doctor's office (9.5%) in their country of origin or in Switzerland (19.1%), respectively. Following the event, 90% (n=27) stated they had learned something new and 93.3% (n=28) wanted to implement the instructions in their daily routine. While 63.3% (n=19) of the respondents knew the consequences of lacking oral hygiene on oral health before the event, this value increased to 96.7% (n=29) reaching statistical significance (p=0.0039). In conclusion, the results of the present study suggest that the implementation of a single information session with OHI in asylum centres may improve the level of knowledge in adolescent asylum seekers and their oral health.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"132 ","pages":"404-413"},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jürgen Wallner, Marcus Rieder, Michael Schwaiger, Mauro Pau, Tomislav Zrnc, Wolfgang Zemann, Philipp Metzler
{"title":"[Metronidazole - spectrum of activity, use and side effects].","authors":"Jürgen Wallner, Marcus Rieder, Michael Schwaiger, Mauro Pau, Tomislav Zrnc, Wolfgang Zemann, Philipp Metzler","doi":"10.61872/sdj-2022-06-03","DOIUrl":"10.61872/sdj-2022-06-03","url":null,"abstract":"<p><p>This contribution gives an overview of the use, therapeutic effects and side effects of the antibiotic substance Metronidazole. Metronidazole is effective in the treatment support of paradontitis, microbial-caused halitosis, perioral skin infections and odontogenic hard or soft tissue abscess formations related to anaerobic bacterial infections. Due to its anti- parasitic effect, Metronidazole is also effective in the treatment of protozoa. In adults and children from 12 years on, 200 mg Metronidazole to a maximum of 2000 mg Metronidazole per day can be administered. In children below 12 years of age, an antibiotic dose of Metronidazole between 20 to 30 mg per kilogram body weight is advised.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"132 6","pages":"433-435"},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}