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Digital journal of ophthalmology : DJO最新文献

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Outcomes of mitomycin C intravascular chemoembolization (MICE) in refractory corneal neovascularization after failed keratoplasty. 丝裂霉素C血管内化疗栓塞治疗角膜移植术失败后难治性角膜新生血管的疗效。
Digital journal of ophthalmology : DJO Pub Date : 2023-01-01 DOI: 10.5693/djo.02.2023.01.002
Sarah Zaher Addeen, Ziad Oyoun, Hussam Alfhaily, Anas Anbari
{"title":"Outcomes of mitomycin C intravascular chemoembolization (MICE) in refractory corneal neovascularization after failed keratoplasty.","authors":"Sarah Zaher Addeen,&nbsp;Ziad Oyoun,&nbsp;Hussam Alfhaily,&nbsp;Anas Anbari","doi":"10.5693/djo.02.2023.01.002","DOIUrl":"https://doi.org/10.5693/djo.02.2023.01.002","url":null,"abstract":"<p><p>Corneal neovascularization is a determinant of corneal graft survival and preservation of immune privilege after keratoplasty. We report the outcomes in 2 patients with failed corneal grafts who underwent mitomycin C (MMC) intravascular chemoembolization (MICE) in the affected eye. A 30-year-old woman with failed penetrating keratoplasty (PK) in the right eye was started on prednisolone acetate eyedrops. Graft sutures were removed, and bevacizumab was injected subconjunctivally. The eye remained intermittently painful, and MICE was performed on the main feeding vessel, with regression of the vessels apparent within the first day following the procedure. The second case was a 40-year-old man who had a history of repaired penetrating injury in the left eye followed by failed PK. Prednisolone acetate eyedrops were initiated, and corneal sutures were removed. The patient failed to improve with three subconjunctival injections of bevacizumab. MICE was performed, but in this case neovascularization did not regress until 20 weeks post-procedure. MMC is thought to inhibit vascular endothelial cell proliferation, but its use in corneal injection is debated. In these cases, MICE was not associated with any concerning adverse events.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"29 1","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125729/pdf/djo-22-259.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9460287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orbital apex inflammation: a curious case of COVID-19. 眼眶顶点炎症：新冠肺炎的一个奇怪病例。
Digital journal of ophthalmology : DJO Pub Date : 2022-07-27 DOI: 10.5693/djo.02.2022.05.001
Ahsan Hussain, Hilary Fazzone, Daniel Elefant, Savannah Kumar, Sana Ali, Abha Amin
{"title":"Orbital apex inflammation: a curious case of COVID-19.","authors":"Ahsan Hussain,&nbsp;Hilary Fazzone,&nbsp;Daniel Elefant,&nbsp;Savannah Kumar,&nbsp;Sana Ali,&nbsp;Abha Amin","doi":"10.5693/djo.02.2022.05.001","DOIUrl":"10.5693/djo.02.2022.05.001","url":null,"abstract":"<p><p>A 25-year-old man presented to an urgent care facility with sudden loss of vision in his right eye, diplopia, and anosmia. He tested positive by reverse-transcription polymerase chain reaction for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Nine days later, he presented at our emergency department, at which time ophthalmic examination revealed reduced visual acuity in the right eye, with poor color vision and a relative afferent pupillary defect. He had a moderate adduction deficit and mild hypertropia of the right eye, with an intermittent exotropia. Magnetic resonance imaging of the orbits revealed asymmetric, abnormal enhancement of the right optic nerve sheath extending to the right orbital apex. His ocular symptoms resolved completely with systemic steroids. All infectious and inflammatory labs returned negative except for COVID-19. Ocular findings have been consistently implicated throughout this pandemic. This case highlights an unidentified presentation with optic nerve involvement and orbital inflammation.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":" ","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"2022-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635761/pdf/djo-21-059.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40485821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Reticular epithelial edema after penetrating keratoplasty in a patient taking netarsudil. 穿透性角膜移植术后网状上皮水肿患者服用奈沙地尔。
Digital journal of ophthalmology : DJO Pub Date : 2022-06-27 eCollection Date: 2022-01-01 DOI: 10.5693/djo.02.2022.02.002
Lauren J Jeang, Ankit S Shah, Jon D Hammer, Sonal S Tuli
{"title":"Reticular epithelial edema after penetrating keratoplasty in a patient taking netarsudil.","authors":"Lauren J Jeang,&nbsp;Ankit S Shah,&nbsp;Jon D Hammer,&nbsp;Sonal S Tuli","doi":"10.5693/djo.02.2022.02.002","DOIUrl":"https://doi.org/10.5693/djo.02.2022.02.002","url":null,"abstract":"<p><p>Netarsudil is a relatively new medication for the treatment of primary open-angle glaucoma and ocular hypertension. It has been associated with red eyes and burning after instillation. Reticular epitheliopathy is a relatively rare complication of netarsudil that has been described in patients with preexisting corneal edema. We report the case of a healthy 76-year-old woman who developed reticular epitheliopathy after full-thickness penetrating keratoplasty that completely resolved following discontinuation of the medication. In cases where netarsudil is initiated for treatment of glaucoma or, off-label, endothelial dysfunction, reticular epithelial edema should be considered in patients complaining of a decline in vision and severe pain.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 8","pages":"34-37"},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255647/pdf/djo-21-020.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40520903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Digital eye strain during the virtual interviews: evidence-based strategies for medical students. 虚拟面试中的数字眼疲劳:医学生的循证策略。
Digital journal of ophthalmology : DJO Pub Date : 2022-06-24 eCollection Date: 2022-01-01 DOI: 10.5693/djo.01.2022.05.003
Deena Dahshan, Jullia A Rosdahl
{"title":"Digital eye strain during the virtual interviews: evidence-based strategies for medical students.","authors":"Deena Dahshan,&nbsp;Jullia A Rosdahl","doi":"10.5693/djo.01.2022.05.003","DOIUrl":"https://doi.org/10.5693/djo.01.2022.05.003","url":null,"abstract":"<p><p>The 2020-2021 residency interview season was the first in which interviews were entirely virtual, and residency interviews may continue to be offered in this format. Digital eye strain can negatively affect applicants' interview experience. We provide an overview of the virtual residency interview experience with a view to providing applicants with solutions that minimize eye strain. Symptoms, contributing factors, and evidence-based interventions for digital eye strain are discussed.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 5","pages":"22-25"},"PeriodicalIF":0.0,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255649/pdf/djo-21-131.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40537006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Migration of retained tarsal bee stinger onto the ocular surface causing superficial keratopathy. 残留的跗骨蜂刺迁移到眼表引起浅表性角膜病变。
Digital journal of ophthalmology : DJO Pub Date : 2022-06-21 eCollection Date: 2022-01-01 DOI: 10.5693/djo.02.2021.10.001
Alexander R Newman, Timothy J Beckman, Braden D Meiklejohn, Matthew D Green
{"title":"Migration of retained tarsal bee stinger onto the ocular surface causing superficial keratopathy.","authors":"Alexander R Newman,&nbsp;Timothy J Beckman,&nbsp;Braden D Meiklejohn,&nbsp;Matthew D Green","doi":"10.5693/djo.02.2021.10.001","DOIUrl":"https://doi.org/10.5693/djo.02.2021.10.001","url":null,"abstract":"<p><p>We report a case of keratopathy due to retained stinger elements following a bee sting and envenomation of the ocular adnexa. A 48-year-old woman presented with a 2-day history of right-sided eye pain, photophobia, and reduced visual acuity. Six days prior to presentation, she had been stung on the right upper eyelid by a bee. Her usual practitioner had removed the stinger and commenced a course of oral antibiotics. Anterior segment examination revealed coarse linear abrasions and superficial punctate keratitis with associated epithelial edema. Eversion of the right upper eyelid revealed the presence of retained stinger lancets near the medial eyelid margin. The retained stinger was removed, and the patient responded well to treatment with topical antibiotics, steroids, and cycloplegia.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 7","pages":"31-33"},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255646/pdf/djo-20-089.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40537021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Spontaneous rupture of secondary iris inclusion cyst causing acute glaucoma and other ocular sequelae. 继发性虹膜包涵囊肿自然破裂，引起急性青光眼等眼部后遗症。
Digital journal of ophthalmology : DJO Pub Date : 2022-06-20 eCollection Date: 2022-01-01 DOI: 10.5693/djo.02.2022.05.002
Julie M Shabto, Kenneth W Price, John C Allen, Caroline Craven, Jeremy K Jones, Jill Wells
{"title":"Spontaneous rupture of secondary iris inclusion cyst causing acute glaucoma and other ocular sequelae.","authors":"Julie M Shabto,&nbsp;Kenneth W Price,&nbsp;John C Allen,&nbsp;Caroline Craven,&nbsp;Jeremy K Jones,&nbsp;Jill Wells","doi":"10.5693/djo.02.2022.05.002","DOIUrl":"https://doi.org/10.5693/djo.02.2022.05.002","url":null,"abstract":"<p><p>A 63-year-old woman with a known secondary iris inclusion cyst in her right eye presented with headache, blurry vision, and eye pain of 3 days' duration. Initial findings were notable for significant decrease in vision and elevated intraocular pressure in the right eye, with diffuse microcystic corneal edema, diffuse anterior chamber flare with minimal cellular reaction, and a significantly decompressed iris inclusion cyst. On gonioscopy, the right eye was open to scleral spur, and no pigment was visualized. Patient history and presentation were consistent with a diagnosis of spontaneous rupture of iris inclusion cyst causing secondary glaucoma. Iris inclusion cysts are not uncommon; however, ocular outcomes are generally benign and limited to obstruction of the pupillary axis.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 6","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255648/pdf/djo-21-147.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40618014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video-based surgical curriculum for open-globe injury repair, III: surgical repair. 开放球损伤修复的视频外科课程，III:外科修复。
Digital journal of ophthalmology : DJO Pub Date : 2022-01-01 DOI: 10.5693/djo.01.2022.08.002
Aliya Siddiqui, Marguerite C Weinert, Catherine M Marando, Tedi Begaj, Yifan Lu, Grayson W Armstrong
{"title":"Video-based surgical curriculum for open-globe injury repair, III: surgical repair.","authors":"Aliya Siddiqui,&nbsp;Marguerite C Weinert,&nbsp;Catherine M Marando,&nbsp;Tedi Begaj,&nbsp;Yifan Lu,&nbsp;Grayson W Armstrong","doi":"10.5693/djo.01.2022.08.002","DOIUrl":"https://doi.org/10.5693/djo.01.2022.08.002","url":null,"abstract":"As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes. This video-based educational curriculum is intended to serve as an efficient yet comprehensive reference for OGI repair. We hope that these video-based articles help surgeons and trainees from around the world find answers to specific surgical questions in OGI management. The curriculum has been divided into six separate review articles, each authored by a different set of authors, to facilitate a systematic and practical approach to the subject of wound types and repair techniques. This third article highlights the use of antibiotics before, during, and after surgery; suture selection; surgical knots, and “ship-to-shore” suturing.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 4","pages":"74-85"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838179/pdf/djo-21-073.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video-based surgical curriculum for open-globe injury repair, II: preparation for open-globe injury surgery. 基于视频的开放球损伤修复外科课程II:开放球损伤手术的准备。
Digital journal of ophthalmology : DJO Pub Date : 2022-01-01 DOI: 10.5693/djo.01.2022.01.002
Jenny C Dohlman, Enchi K Chang, Tedi Begaj, Yifan Lu, Grayson W Armstrong
{"title":"Video-based surgical curriculum for open-globe injury repair, II: preparation for open-globe injury surgery.","authors":"Jenny C Dohlman,&nbsp;Enchi K Chang,&nbsp;Tedi Begaj,&nbsp;Yifan Lu,&nbsp;Grayson W Armstrong","doi":"10.5693/djo.01.2022.01.002","DOIUrl":"https://doi.org/10.5693/djo.01.2022.01.002","url":null,"abstract":"","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 3","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635762/pdf/djo-21-072.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10703928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conjunctival Merkel cell carcinoma: case report and review of the literature. 结膜默克尔细胞癌:病例报告及文献复习。
Digital journal of ophthalmology : DJO Pub Date : 2022-01-01 DOI: 10.5693/djo.02.2022.02.003
Mai N Tran, Gishan Ratnayake, David Wong, Lindsay A McGrath
{"title":"Conjunctival Merkel cell carcinoma: case report and review of the literature.","authors":"Mai N Tran,&nbsp;Gishan Ratnayake,&nbsp;David Wong,&nbsp;Lindsay A McGrath","doi":"10.5693/djo.02.2022.02.003","DOIUrl":"https://doi.org/10.5693/djo.02.2022.02.003","url":null,"abstract":"<p><p>Merkel cell carcinoma (MCC) of the conjunctiva is rare. We report the case of a 73-year-old man who presented with unilateral foreign body sensation and blurred vision. A rapidly enlarging conjunctival lesion was identified and excised. The histopathological diagnosis was poorly differentiated squamous cell carcinoma, later reclassified as neuroendocrine / Merkel cell carcinoma following excision on subsequent recurrence. The patient developed lymph node and widespread metastatic disease. The challenges of diagnosing MCC at this site are discussed and the literature on treatment options for this aggressive disease is reviewed.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 3","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635759/pdf/djo-21-061.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10529870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of fluocinolone acetonide intravitreal implant to manage chronic panuveitis for long-term inflammatory control without interfering with systemic immunity. 应用醋酸氟西诺酮玻璃体内植入治疗慢性全葡萄膜炎，在不干扰全身免疫的情况下长期控制炎症。
Digital journal of ophthalmology : DJO Pub Date : 2022-01-01 DOI: 10.5693/djo.02.2022.10.002
Peter Y Chang
{"title":"Use of fluocinolone acetonide intravitreal implant to manage chronic panuveitis for long-term inflammatory control without interfering with systemic immunity.","authors":"Peter Y Chang","doi":"10.5693/djo.02.2022.10.002","DOIUrl":"https://doi.org/10.5693/djo.02.2022.10.002","url":null,"abstract":"<p><p>We report 2 patients with chronic panuveitis who were treated with fluocinolone acetonide intravitreal implant (Yutiq, EyePoint Pharmaceuticals Inc, Watertown, MA) intended to control ocular inflammation long term without interfering with systemic immunity. The first case was a man in his 50s referred for ocular complaints in the setting of ongoing immunotherapy for the treatment of metastatic melanoma. He was diagnosed with bilateral drug-induced panuveitis. Treatment objectives were outlined as reduction of inflammation, prevention of uveitis recurrence, and continuation of systemic immunomodulatory therapy in order to maintain malignancy remission; the patient was treated with fluocinolone acetonide intravitreal implant bilaterally and at 18 months' follow-up had 20/20 bilateral visual acuity and no inflammation. In case 2, a woman in her 70s, presented with a 2-month history of worsening floaters and blurry vision. She was phakic, with bilateral nuclear sclerotic cataracts, 1+ vitreous cells and 2+ haze, diffuse vasculitis, and central leakage around the optic nerve and posterior pole. She was diagnosed with bilateral idiopathic panuveitis with retinal vasculitis. The patient continued to do well at 1 year following intravitreal implantation with fluocinolone acetonide.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"28 4","pages":"119-125"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838181/pdf/djo-22-094.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10550861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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