European Journal of Radiology Open最新文献

{"title":"Myocardial transit time mapping by CMR: A novel potential parameter of microcirculatory dysfunction in hypertrophic cardiomyopathy with and without atrial fibrillation","authors":"Junlin Yang ,&nbsp;Yong Cheng ,&nbsp;Jinxiu Yang ,&nbsp;Yuncheng Li ,&nbsp;Zhen Wang ,&nbsp;Shutian An ,&nbsp;Jun Wang ,&nbsp;Yongqiang Yu ,&nbsp;Ren Zhao ,&nbsp;Xiaohu Li","doi":"10.1016/j.ejro.2026.100726","DOIUrl":"10.1016/j.ejro.2026.100726","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to explore myocardial transit time (MyoTT) by cardiovascular magnetic resonance (CMR) as a potential parameter of coronary microvascular dysfunction (CMD) in hypertrophic cardiomyopathy (HCM) with and without atrial fibrillation (AF).</div></div><div><h3>Materials and Methods</h3><div>This study enrolled 50 patients with HCM and 50 healthy control subjects to assess cardiac function, native T1, extracellular volume (ECV), myocardial strain, and MyoTT. Factors associated with HCM status were estimated by logistic regression analyses, adjusting for potential confounders. Meanwhile, we evaluated the discriminative performance of the aforementioned parameters for HCM (vs control) and for AF status among HCM patients.</div></div><div><h3>Results</h3><div>In the HCM and control groups, the HCM group exhibited significant reductions in LV-GLS, RV-EDVI, and RV-ESVI (all P &lt; 0.05) and significant increases in LVMI, LVGPWT, native T1 values, ECV values, absolute MyoTT values and presence of LGE (all P &lt; 0.05). Logistic regression analysis revealed HCM was significantly associated with MyoTT, native T1, ECV and LV-GLS. In HCM with and without AF, the HCM with AF group showed nominally higher native T1 values and absolute MyoTT values before correction. Logistic regression analysis revealed HCM with AF was significantly associated with MyoTT and native T1. The AUCs for ECV, MyoTT, LV-GLS, and native T1 were 0.828, 0.848, 0.708, and 0.862, respectively (P &lt; 0.05). The AUCs for discriminating HCM with AF from HCM without AF for MyoTT and native T1 were 0.740 and 0.681, respectively (P &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>MyoTT levels are elevated in patients with HCM, particularly when AF is present. This suggests that MyoTT may reflect CMD-related alterations in HCM, especially in those with AF.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100726"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eye tracking as a tool to quantify the effects of CAD display on radiologists’ interpretation of chest radiographs","authors":"Daisuke Matsumoto ,&nbsp;Tomohiro Kikuchi ,&nbsp;Yusuke Takagi ,&nbsp;Soichiro Kojima ,&nbsp;Ryoma Kobayashi ,&nbsp;Daiju Ueda ,&nbsp;Kohei Yamamoto ,&nbsp;Sho Kawabe ,&nbsp;Harushi Mori","doi":"10.1016/j.ejro.2026.100731","DOIUrl":"10.1016/j.ejro.2026.100731","url":null,"abstract":"<div><h3><em>Background:</em></h3><div>Computer-aided detection (CAD) systems for chest radiographs are widely used; however, concurrent reader displays such as bounding-box (BB) highlights may influence interpretation. This pilot study used eye tracking to examine which aspects of visual search were affected by these factors.</div></div><div><h3><em>Methods:</em></h3><div>We sampled 180 chest radiographs from the VinDR-CXR dataset: 120 with solitary pulmonary nodules or masses and 60 without. BBs were configured for 80 % display sensitivity and specificity. Three radiologists (with 11, 5, and 1 years of experience) interpreted each case twice—once with BBs visible and once without—after a ≥ 2-week washout. Eye movements were recorded using an EyeTech VT3 Mini. Metrics included interpretation time, time to first fixation, lesion dwell time, total gaze-path length, and lung-field coverage. Outcomes were modeled using a linear mixed model with the reading condition set as a fixed effect and case and reader as random intercepts. Primary analysis was restricted to true positives (n = 96).</div></div><div><h3><em>Results:</em></h3><div>Concurrent BB display prolonged interpretation time by 4.9 s (p &lt; 0.001) and increased lesion dwell time by 1.3 s (p &lt; 0.001). Total gaze-path length increased by 2076 pixels (p &lt; 0.001), and lung-field coverage increased by 10.5 % (p &lt; 0.001). The time to first fixation was reduced by 1.3 s (p &lt; 0.001).</div></div><div><h3><em>Conclusion:</em></h3><div>Eye tracking revealed measurable changes in search behavior associated with concurrent BB display during chest radiograph interpretation. These findings support this approach and highlight the need for larger studies across modalities and clinical contexts.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100731"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The value of virtual non-contrast images derived from dual-energy spectral CT in the short-term efficacy assessment of hepatocellular carcinoma after TACE","authors":"Mingzi Gao ,&nbsp;Taoming Du ,&nbsp;Kai Zhang ,&nbsp;Cheng Yan ,&nbsp;Changchun Liu ,&nbsp;Can Su ,&nbsp;Jingwen Zhang ,&nbsp;Yingxuan Wang ,&nbsp;Jing Han ,&nbsp;Mingxin Zhang ,&nbsp;Yujie Chen ,&nbsp;Jinghui Dong ,&nbsp;Liqin Zhao","doi":"10.1016/j.ejro.2026.100730","DOIUrl":"10.1016/j.ejro.2026.100730","url":null,"abstract":"<div><h3>Purpose</h3><div>To explore the clinical utility of virtual non-contrast (VNC) images from dual-energy spectral CT (DEsCT) in short-term follow-up of hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE).</div></div><div><h3>Methods</h3><div>66 HCC patients with DEsCT 4–6 weeks post-TACE were retrospectively enrolled. VNC images were generated from arterial (VNC_AP) and portal venous phase (VNC_PVP) images. Beam-hardening artifacts surrounding lipiodol were assessed on true non-contrast (TNC) and both VNC images. Lipiodol removal degree was classified into 4 grades at 25 % intervals on both VNC images. Residual viable tumor (RVT) was diagnosed using contrast-enhanced CT or MRI. CT attenuation values of RVT, adjacent normal hepatic parenchyma (ANHP), and lipiodol removal area (LRA) were compared among TNC and VNC images. Diagnostic performance of CT attenuation values on VNC images was compared for the three areas.</div></div><div><h3>Results</h3><div>34 patients showed beam-hardening artifacts surrounding lipiodol on TNC images, which were reduced or eliminated on VNC_AP and VNC_PVP images in 28 and 26 cases. All HCCs showed good lipiodol removal on both VNC images, with 7 lesions at Grade 3 and 59 lesions at Grade 4. On TNC images, significant CT attenuation value differences were found between LRA and ANHP, and LRA and RVT (P &lt; 0.001), but not between RVT and ANHP (P &gt; 0.05). Both VNC images showed good diagnostic efficacy for these three areas, with LRA having the lowest value.</div></div><div><h3>Conclusion</h3><div>VNC images demonstrate superior lipiodol removal efficacy and beam-hardening artifacts reduction, facilitating precise RVT delineation and TACE-induced necrosis assessment, complementing contrast-enhanced CT for TACE efficacy assessment in HCC.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100730"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of preoperative co-occurring intervertebral disc-related degenerative features with one-year lumbar discectomy outcomes: A proposal for and preliminary testing of a novel MRI-based criterion","authors":"Tero Korhonen ,&nbsp;Jyri Järvinen ,&nbsp;Juha Pesälä ,&nbsp;Marianne Haapea ,&nbsp;Pietari Kinnunen ,&nbsp;Jaakko Niinimäki","doi":"10.1016/j.ejro.2026.100729","DOIUrl":"10.1016/j.ejro.2026.100729","url":null,"abstract":"<div><h3>Purpose</h3><div>This study developed a criterion for preoperative co-occurring intervertebral disc (IVD)-related degenerative features and evaluated its association with one-year outcomes following single-level lumbar discectomy.</div></div><div><h3>Methods</h3><div>The novel literature-based criterion, termed “Advanced Preoperative Degeneration” (APD), required the operated segment to exhibit preoperatively at least two advanced-level phenotypes from endplate damage (EPD), Modic changes (MC), and IVD degeneration. Subsequently, a retrospective single-center register-based study of patients treated with single-level micro- or endoscopic lumbar discectomy at a tertiary-level hospital between 2017 and 2022 was performed. The patients were categorized into three groups, APD-positive, APD1/3, and APD0, based on the presence of two or more, one, or none of the required phenotypes, respectively. A mixed-effects model was employed to assess between-group differences in improvement of LBP and leg pain (0–100 VAS), disability (ODI), and quality of life (EQ-5D-3L) from baseline to the one-year postoperative time point.</div></div><div><h3>Results</h3><div>The cohort consisted of 140 patients (mean age: 45.3 years; 81 [57.9 %] male). Overall, the patients exhibited significant improvements in all PROMs after discectomy. However, at the one-year follow-up, the APD-positive group exhibited significantly higher leg pain and disability levels than the APD0 group, with mean scores of 31.4 versus 19.6 for leg pain and 20.6 versus 12.0 for ODI, respectively.</div></div><div><h3>Conclusion</h3><div>This study introduces a novel approach by integrating preoperative co-occurring IVD-related degenerative features into a composite APD criterion. Meeting the APD criterion was associated with significantly poorer one-year outcomes for leg pain and disability following lumbar discectomy.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100729"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of coronary CTA versus exercise electrocardiography in acute chest pain: A propensity score-matched study in the emergency department","authors":"Alessandro Marchetti ,&nbsp;Eleonora Moliterno ,&nbsp;Giuseppe Rovere ,&nbsp;Lorenzo Giarletta ,&nbsp;Alessio Perazzolo ,&nbsp;Domenico Amatulli ,&nbsp;Antonio De Vita ,&nbsp;Massimo Muciaccia ,&nbsp;Francesco Lauriero ,&nbsp;Giancarlo Savino ,&nbsp;Anna Rita Larici ,&nbsp;Biagio Merlino ,&nbsp;Marcello Covino ,&nbsp;Gaetano Antonio Lanza ,&nbsp;Giovanna Liuzzo ,&nbsp;Francesco Franceschi ,&nbsp;Francesco Burzotta ,&nbsp;Luigi Natale ,&nbsp;Riccardo Marano","doi":"10.1016/j.ejro.2026.100734","DOIUrl":"10.1016/j.ejro.2026.100734","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the clinical impact and operational efficiency of exercise electrocardiography (ex-ECG) and coronary CT angiography (CCTA) in the diagnostic-therapeutic care pathway of patients presenting to the Emergency Department (ED) with acute chest pain (ACP) and suspected non-ST-elevation acute coronary syndrome (NSTE-ACS).</div></div><div><h3>Methods</h3><div>This single-center retrospective cohort study enrolled 428 consecutive patients presenting with ACP between January 2022 and December 2023. After propensity score matching (PSM) for age, sex, Heart Score, and triage code, two balanced groups of 214 patients each underwent either -ex-ECG or CCTA. Primary outcomes included diagnostic test positivity, hospital admission rate, and ED length-stay. Secondary outcomes included need for invasive coronary angiography (ICA) and revascularization rates.</div></div><div><h3>Results</h3><div>No statistically significant differences were found in test positivity (42 vs 31 patients, p = 0.157) or hospital admission rates (42 vs 30 patients, p = 0.121) between ex-ECG and CCTA groups. The ICA rates were similar (36 vs 32 patients, p = 0.597), as were revascularization rates (13 patients each, p = 1.000). However, discharged patients undergoing CCTA had significantly shorter total ED length-stay compared to ex-ECG (1710 vs 1841 min, p &lt; 0.001), representing a 7.12 % reduction.</div></div><div><h3>Conclusion</h3><div>Both ex-ECG and CCTA demonstrate comparable clinical impact and operational efficiency in patients with ACP and suspected NSTE-ACS. CCTA offers effective advantages with significantly reduced ED length-stay for a safe discharge of the patients, improving resource management without compromising diagnostic quality. These findings support the increasing adoption of CCTA in the diagnostic pathway for ACP and suspected NSTE-ACS in the ED setting.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100734"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of high-iodine concentration contrast material for dual-energy CT angiography on arterial visualization: A single-blind, randomized controlled trial","authors":"Yoshifumi Noda ,&nbsp;Shoma Nagata ,&nbsp;Taketo Suto ,&nbsp;Masashi Asano ,&nbsp;Takuma Ishihara ,&nbsp;Takeshi Iwata ,&nbsp;Toshiharu Miyoshi ,&nbsp;Nobuyuki Kawai ,&nbsp;Tetsuro Kaga ,&nbsp;Masayuki Matsuo","doi":"10.1016/j.ejro.2026.100733","DOIUrl":"10.1016/j.ejro.2026.100733","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the effect of high-iodine concentration contrast material for dual-energy CT angiography (DECTA) on arterial visualizations by comparing it with medium-iodine concentration.</div></div><div><h3>Method</h3><div>This prospective, single-blind, randomized controlled trial included 100 consecutive participants undergoing DECTA from November 2023 to February 2025. The participants were randomly assigned into two protocols: receiving high-iodine concentration contrast material of 370 mgI/mL (Group A, <em>n</em> = 51) and receiving medium-iodine concentration of 300 mgI/mL (Group B, <em>n</em> = 49). The axial, coronal, and volume-rendered (VR) images were reconstructed at 40 keV in both groups. Two radiologists reviewed three image types and assessed the arterial visualizations using a five-point scale. The primary outcome was the score for the iliolumbar artery on the VR images, whereas secondary outcomes were the scores for all others. The Wilcoxon rank sum test was conducted to compare the outcomes between the two groups.</div></div><div><h3>Results</h3><div>No statistical significance in terms of the score for the iliolumbar artery on the VR images was found between the two groups; however, the median score was higher in Group A than in Group B (3.5 vs. 3.0; <em>P</em> = .05). The scores for secondary outcomes in Group A were equal to or greater than that in Group B, and significant differences were observed, especially in the small arteries, including the bronchial, internal thoracic, intercostal, left gastric, and inferior phrenic arteries (<em>P</em> &lt; .05).</div></div><div><h3>Conclusion</h3><div>In small arteries, the protocol with high-iodine concentration contrast material exhibited better arterial visualizations compared with medium-iodine concentration in DECTA at 40 keV.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100733"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The consequences of percutaneous transhepatic biliary drainage (PTBD) in patients with tumoral obstructive jaundice: A retrospective study and review of literature","authors":"Javad Jalili,&nbsp;Yaser Ahmadi,&nbsp;Mahsa Karbasi,&nbsp;Sarah Vaseghi,&nbsp;Mahdiyeh Baastani Khajeh,&nbsp;Sahar Rezaei,&nbsp;Esmaeil Gharepapagh,&nbsp;Alireza Motamedi","doi":"10.1016/j.ejro.2025.100722","DOIUrl":"10.1016/j.ejro.2025.100722","url":null,"abstract":"<div><h3>Background</h3><div>Percutaneous transhepatic biliary drainage (PTBD) is widely used in malignant obstructive jaundice (MOJ), but most series report aggregate complication rates without stratification by tumor type. This limits individualized risk counseling and hampers benchmarking across centers.</div></div><div><h3>Objective</h3><div>To evaluate short-term outcomes of PTBD in a large single-center cohort, with a focus on tumor-specific complication patterns using patient-level attribution and robust statistical methods.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed 453 patients with MOJ undergoing PTBD (2017–2022). Complications within 30 days were recorded at the patient level, with downstream sequelae attributed to the index event. Exact tests and Firth penalized logistic regression were applied to mitigate sparse-data bias. Survival status was documented through 90 days.</div></div><div><h3>Results</h3><div>Technical success was 100 %, and mean bilirubin declined significantly within 48 h. Twenty-two complications occurred in 21 patients (4.6 %), lower than most published series. Catheter displacement (1.5 %) was the most frequent event, while severe bleeding (0.2 %) and biliary peritonitis (0.6 %) were rare and managed without surgery. No cholangitis was observed. Complications were most frequent in cholangiocarcinoma and pancreatic cancer, although differences across tumor types were not statistically significant. Follow-up was complete; no deaths occurred within 90 days, yielding 30-day and 90-day survival rates of 100 %.</div></div><div><h3>Conclusions</h3><div>PTBD is highly effective and safe in MOJ, with lower complication rates than many prior reports. Tumor-specific analysis revealed variation in complication subtypes but no significant differences in overall incidence. The rigorous methodology and complete follow-up provide a robust framework for individualized risk profiling and multicenter benchmarking.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100722"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated diagnosis of usual interstitial pneumonia on chest CT via the mean curvature of isophotes","authors":"Peter Savadjiev ,&nbsp;Morteza Rezanejad ,&nbsp;Sahir Bhatnagar ,&nbsp;David Camirand ,&nbsp;Claude Kauffmann ,&nbsp;Kaleem Siddiqi ,&nbsp;Ronald J. Dandurand ,&nbsp;Patrick Bourgouin ,&nbsp;Carl Chartrand-Lefebvre ,&nbsp;Alexandre Semionov","doi":"10.1016/j.ejro.2025.100723","DOIUrl":"10.1016/j.ejro.2025.100723","url":null,"abstract":"<div><h3>Purpose</h3><div>To test whether the mean curvature of isophotes (MCI), a geometric image transformation, can be used to improve automatic detection on chest CT of Usual Interstitial Pneumonia (UIP), a determining radiological pattern in the diagnosis of Interstitial Lung Diseases (ILD).</div></div><div><h3>Materials and methods</h3><div>This retrospective study included chest CT scans from 234 patients (123 female,111 male; mean age: 61.6 years; age range: 18–90 years) obtained at two independent institutions between 2007 and 2024.</div><div>Three different classification models were trained on the original CT images and separately on MCI-transformed CT images: (1) a previously published deep learning model for classifying fibrotic lung disease on chest CT, (2) a classification pipeline based on the EfficientNet-V2 convolutional neural network architecture, and (3) a non-deep-learning model based on the functional principal component analysis (FPCA) of density functions of voxel intensity.</div><div>All models were trained on data from the first institution and evaluated on data from the second institution with the recall-macro, precision-macro and F1-macro scores. Performance difference between classifier pairs was tested with the Stuart-Maxwell marginal homogeneity test.</div></div><div><h3>Results</h3><div>For a fixed model architecture and training algorithm, MCI-transformed images yield comparable or better classification performance than the original CT images. The best performance improvement achieved with MCI compared to CT was: recall-macro 0.83 vs 0.57, precision-macro 0.81 vs 0.50, F1-macro 0.80 vs 0.49, p = 4.2e-5.</div></div><div><h3>Conclusion</h3><div>MCI may be a valuable addition to existing AI systems for screening for UIP on chest CT.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100723"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of single-phase DECT as an alternative to triple-phase CT for imaging-defined risk factors assessment in neuroblastoma for dose reduction","authors":"Ruifang Sun ,&nbsp;Haoyan Li ,&nbsp;Bei Wang ,&nbsp;Huiying Kang ,&nbsp;Runtong Lu ,&nbsp;Zhenpeng Chen ,&nbsp;Yun Peng ,&nbsp;Jihang Sun","doi":"10.1016/j.ejro.2026.100732","DOIUrl":"10.1016/j.ejro.2026.100732","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the feasibility of evaluating Imaging-Defined Risk Factors (IDRFs) in Neuroblastoma (NB) patients using venous-phase (VP)-only images in dual-energy CT for radiation dose reduction and examination workflow optimization, compared with conventional triple-phase CECT.</div></div><div><h3>Materials and methods</h3><div>Ninety-four pediatric NB patients (ages 4.92 ± 3.45 y, range 0–17 y), who underwent triple-phase DECT were included. The standard 68 keV images reconstructed using 50 % adaptive statistical iterative reconstruction-V (ASIR-V) served as the control group. The 40 keV images in VP with deep learning image reconstruction (DLIR) were used as the study group. Objective measurements included CT values and standard deviations of the aorta, back muscles, NB lesions; contrast-to-noise ratio (CNR) of the aorta, and edge-rise slope (ERS) of NB lesions and compared by using paired Wilcoxon tests. Two pediatric radiologists independently reviewed images for IDRFs and used a 5-point scale to assess images quality. Weighted Cohen's kappa was generated to analyze the inter-rater differences.</div></div><div><h3>Results</h3><div>The study group had higher arterial CT values (440.81 ± 79.93 HU vs. 340.35 ± 61.14 HU, p &lt; 0.001), similar CNR (30.43 ± 10.91 vs. 28.17 ± 10.05, p = 0.110), and higher ERS (129.31 ± 41.32 vs. 114.06 ± 36.33, p = 0.002). Two radiologists showed no difference in IDRFs assessment with good intra-group consistency, and all images met diagnostic needs with image quality scores exceeded 3. The single-phase DECT reduced radiation dose to 108.84 ± 50.49 mGy-cm, over 60 % lower than the triple-phase CECT.</div></div><div><h3>Conclusion</h3><div>Single venous-phase 40 keV-DECT images demonstrate feasibility for evaluating IDRFs in pediatric NB patients, saving about 60 % radiation dose and optimizing the examination workflow compared to the conventional triple-phase approach.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100732"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary 0.55 T MRI to visualize interstitial lung disease – An exploratory study","authors":"Nadine Bayerl ,&nbsp;Claudius S. Mathy ,&nbsp;Christina Bergmann ,&nbsp;Tobias Bäuerle ,&nbsp;Lisa C. Adams ,&nbsp;Armin M. Nagel ,&nbsp;Jörg H.W. Distler ,&nbsp;Teresa Gerhalter ,&nbsp;Michael Uder ,&nbsp;Rafael Heiss ,&nbsp;Stephan Ellmann","doi":"10.1016/j.ejro.2025.100720","DOIUrl":"10.1016/j.ejro.2025.100720","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the feasibility of contemporary 0.55 T MRI for visualizing interstitial lung disease (ILD) compared to high-resolution computed tomography (HRCT) in an exploratory first-experience study.</div></div><div><h3>Materials and methods</h3><div>Thirty participants (mean age 60 ± 13 years; 13 females) with rheumatologic ILD underwent HRCT and 0.55 T MRI within 31 days. MRI protocols included proton-density-weighted turbo-spin-echo sequences (transverse) and T2-weighted short-tau inversion recovery sequences (coronal). Three blinded radiologists independently assessed overall disease extent, ground-glass opacity (GGO), reticulation, and emphysema using a semi-quantitative scoring system. Differences between modalities were tested using Wilcoxon signed-rank tests, and Bland-Altman analysis evaluated systematic bias.</div></div><div><h3>Results</h3><div>Overall disease extent showed no statistically significant difference between low-field MRI and HRCT (median 22.5 % vs. 24.5 %), with excellent interobserver agreement (MRI ICC = 0.94; HRCT ICC = 0.97). MRI significantly overestimated GGO (13.1 % vs. 9.7 %) and underestimated reticulation (8.1 % vs. 11.4 %) compared to HRCT. Bland-Altman analysis confirmed no systematic bias for overall disease extent but consistent overestimation of GGO and underestimation of reticulation on MRI.</div></div><div><h3>Conclusions</h3><div>Contemporary 0.55 T MRI showed no statistically significant difference in overall ILD extent compared to HRCT but tended to overestimate GGO and underestimate reticulation. Despite these limitations, 0.55 T MRI represents a promising candidate for future development as a radiation-free alternative for gross disease burden assessment in ILD, warranting further technical refinement before routine clinical use.</div></div>","PeriodicalId":38076,"journal":{"name":"European Journal of Radiology Open","volume":"16 ","pages":"Article 100720"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145939333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}