Addictive Behaviors Reports最新文献

{"title":"Investigating psychological and motivational predictors of problematic smartphone use among Smartphone-based Social Networking Service (SNS) users","authors":"Min-Jung Kwak ,&nbsp;Dai-Jin Kim","doi":"10.1016/j.abrep.2023.100506","DOIUrl":"10.1016/j.abrep.2023.100506","url":null,"abstract":"<div><p>Given that the active use of certain smartphone applications is associate with problematic smartphone use, it has been proposed that certain smartphone applications are more addictive than others, such as Social Networking Services (SNS). Still, studies that consider smartphone users’ main usage application which are known to influence the users’ problematic smartphone use, such as SNS, remain to be explored. Thus, the current study aims to investigate the psychological and motivational predictors of problematic smartphone use in a sample of smartphone-based SNS users whose main device usage is SNS. A series of mean comparison tests and binary logistic regression were performed in this study. Of the 433 smartphone-based SNS users, 218 were male (50.3%) and 215 were female (49.7%). Age of 433 participants ranged from 20 to 40, and mean age was 30.75 (SD = 7.84). 73 participants (16.9%) were sorted into the high-risk problematic smartphone use group and 360 participants (83.1%) were categorized as the normal user group. The finding from binary regression analysis showed that reward responsiveness from the Behavioral Activation System (BAS), a lack of self-control, and anxiety significantly increased the odds of problematic smartphone use of the smartphone-based SNS users. Reward responsiveness was found to be the most powerful predictor. Our findings broaden the existing literature and provide implications to reduce addictive smartphone use relating to smartphone-based SNS usage.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"18 ","pages":"Article 100506"},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10180996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative examination of social identity and stigma among adolescents recovering from alcohol or drug use","authors":"Sophia H. Blyth ,&nbsp;Kiefer Cowie ,&nbsp;Jordan Jurinsky ,&nbsp;Emily A. Hennessy","doi":"10.1016/j.abrep.2023.100505","DOIUrl":"10.1016/j.abrep.2023.100505","url":null,"abstract":"<div><h3>Introduction</h3><p>Alcohol and other drug (AOD) use disorders are stigmatized conditions, but little is known about youth’s experience of this stigma, which may threaten their developing social identity and recovery process. This study investigates youth’s perceptions of AOD use-related stigma in the context of their social identity.</p></div><div><h3>Methods</h3><p>This study uses data from 12 youth (ages 17–19) who were in recovery from problematic AOD use. Participants completed a Social Identity Mapping in Addiction Recovery (SIM-AR) exercise, in which they created a visual map of their social groups, and semi-structured interview, in which participants were asked about their experience creating their SIM-AR and reflections on their social network. SIM-AR data were descriptively analyzed, and interviews were thematically analyzed for instances of stigma.</p></div><div><h3>Results</h3><p>Using stigmatizing terminology, participants expressed some stigmatizing attitudes towards themselves and others in their network who used substances and perceived both positive and negative reactions from those who knew about their disorder. Findings suggest that youth may experience some internalized stigma and perceive stigma from others in their social networks, which may be a barrier to the development of a healthy social identity and engagement in recovery supports.</p></div><div><h3>Conclusions</h3><p>These findings should be considered when seeking to engage youth in treatment and recovery programming. Despite the small sample, the findings suggest the importance of considering how stigma may influence adolescents’ treatment and recovery experience in the context of their social environment.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"18 ","pages":"Article 100505"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/82/main.PMC10319988.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9809285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher perceived stress during admission is associated with shorter retention in short-term residential substance use disorder treatment.","authors":"Orrin D Ware, Paul Sacco, John G Cagle, Jodi J Frey, Fernando A Wagner, Alexandra S Wimberly, Bernard Gyebi-Foster, Mayra Diaz, Kisun Peters, Sarah E Zemore","doi":"10.1016/j.abrep.2023.100502","DOIUrl":"10.1016/j.abrep.2023.100502","url":null,"abstract":"<p><strong>Introduction: </strong>Over one million people in the U.S. received residential treatment for a substance use disorder (SUD) in 2020. Longer treatment retention is associated with better outcomes (e.g., reduced substance use). Entering treatment with higher stress may be associated with shorter retention. This paper examines the impact of perceived stress at admission on SUD treatment retention in short-term residential treatment.</p><p><strong>Methods: </strong>A sample of 271 treatment episodes with admissions between October 2019 and February 2020 were collected from de-identified records of an urban mid-Atlantic adult 28-day short-term residential SUD treatment facility. Treatment completion involved finishing 28 days. Sociodemographic, substance use, perceived stress, and treatment discharge variables were analyzed. Bivariate analyses examined differences between treatment completion and early discharge, and Cox regression investigated the effect of perceived stress on treatment retention with covariates.</p><p><strong>Results: </strong>The sample was primarily male (73.8%) and non-Hispanic Black (71.6%). A majority used heroin as their primary substance (54.6%) and reported polysubstance use (72.3%). About half (51.3%) completed treatment, and completed an average of 18.7 (<i>SD</i> = 10.7) days. Those who prematurely discharged from treatment stayed an average of 8.9 (<i>SD</i> = 7.0) days. The Cox regression model found that higher perceived stress (adjusted hazard ratio (AHR) = 1.028; 95% CI = [1.005, 1.053], <i>p</i> =.019) and a race/ethnicity other than non-Hispanic Black (AHR = 1.546, 95% CI = [1.037, 2.305], <i>p</i> =.033) predicted premature discharge.</p><p><strong>Conclusions: </strong>Perceived stress at admission is associated with shorter treatment retention. Early stress management interventions may help increase treatment retention.</p>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"1 1","pages":"100502"},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53921781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Losses disguised as wins” in electronic gambling machines contribute to win overestimation in a large online sample","authors":"Dan Myles ,&nbsp;Daniel Bennett ,&nbsp;Adrian Carter ,&nbsp;Murat Yücel ,&nbsp;Lucy Albertella ,&nbsp;Cassandra de Lacy-Vawdon ,&nbsp;Charles Livingstone","doi":"10.1016/j.abrep.2023.100500","DOIUrl":"10.1016/j.abrep.2023.100500","url":null,"abstract":"<div><h3>Introduction</h3><p>Losses disguised as wins (LDWs) are a salient type of losing outcome common to electronic gambling machines (EGMs). These events occur when a gambling payout is less than the amount wagered (i.e., a net loss) but is nonetheless accompanied by the sounds and animations that accompany genuine wins. Previous lab-based studies have reported that participants tend to overestimate genuine wins when LDWs are present. This study reports an independent replication of these findings in a large online sample that included a substantial number of individuals reporting high-risk gambling and frequent EGM users.</p></div><div><h3>Methods</h3><p>This online study recruited a sample of 940 participants who were randomly assigned to view one of two brief videos. Each video displayed a short period of simulated online slot machine gambling and included 2 genuine wins and either 3 or 0 LDWs. Participants were asked to estimate the number of times a win occurred that <em>was more than the amount bet</em>. Participants also completed the Problem Gambling Severity Index.</p></div><div><h3>Results</h3><p>The mean estimated number of genuine wins was significantly larger for the condition displaying LDWs, 3.02 [95% CI = 2.82, 3.21] than the control condition, 2.14 [1.98, 2.30], <em>t</em>(887.66) = 6.78, <em>d</em> = 0.44, p &lt;.001.</p></div><div><h3>Conclusions</h3><p>We replicated the LDW‐triggered win overestimation effect previously reported in lab-based experiments that have recruited smaller samples. This effect was robust in both low-risk and high-risk groups, indicating that even experienced gamblers remain susceptible. Exploratory modelling suggested only a minority of individuals were uninfluenced by LDWs.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"18 ","pages":"Article 100500"},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44697442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-medical prescription opioid use among high school students in 38 U.S. States","authors":"Himani Byregowda ,&nbsp;Rachel Alinsky ,&nbsp;Xinzi Wang ,&nbsp;Renee M. Johnson","doi":"10.1016/j.abrep.2023.100498","DOIUrl":"10.1016/j.abrep.2023.100498","url":null,"abstract":"<div><h3>Background</h3><p>Lifetime prevalence of non-medical prescription opioid use (NMPOU) among adolescents exceeds 10%. Building on that work, we estimate lifetime and recent (i.e., past 30-day) NMPOU and examine associations with alcohol and cannabis use.</p></div><div><h3>Methods</h3><p>We used 2019 YRBS data from 38 states with a question on lifetime NMPOU (n = 151,910), a subsample of 8 states also inquired about recent NMPOU (n = 28,439). We estimated the prevalence and frequency of NMPOU for boys and girls in each state. Multivariable logistic regression was used to derive odds ratios (OR) and 95% confidence intervals (CIs) representing recent NMPOU in association with alcohol and cannabis use adjusting for state, race/ethnicity, and grade.</p></div><div><h3>Results</h3><p>The prevalence of lifetime NMPOU ranged from 9.4% to 22.7% for girls and 8.6% to 23.2% for boys; significant sex difference in Florida. Recent NMPOU among lifetime users ranged from 33.0% to 50.7% for girls and 40.7% to 52.3% for boys, no significant sex differences. Students reporting recent NMPOU had significantly higher odds of recent alcohol (OR: 5.1, 95% CI: 4.3–6.1) and cannabis use (OR: 3.7, 95% CI: 2.8–4.8). Higher frequency (1–2 and ≥ 3 times vs. 0 times) of NMPOU had significantly greater odds of alcohol (3–9-fold) and cannabis use (3–5-fold). The magnitude of association was higher for boys compared to girls.</p></div><div><h3>Conclusion</h3><p>The prevalence of recent NMPOU among lifetime users is high and is associated with alcohol and cannabis use. NMPOU can be a steppingstone towards other forms of opioid use therefore, opioid prevention programs should emphasize prescription drug misuse and consider socio-contextual and geographical variations.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"17 ","pages":"Article 100498"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/20/8b/main.PMC10234833.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9950945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the 7-Item Domain-General Gambling Harm Scale (DGHS-7)","authors":"André Syvertsen ,&nbsp;Joakim H. Kristensen ,&nbsp;Matthew Browne ,&nbsp;En Li ,&nbsp;Ståle Pallesen","doi":"10.1016/j.abrep.2023.100499","DOIUrl":"10.1016/j.abrep.2023.100499","url":null,"abstract":"<div><h3>Introduction</h3><p>Gambling can cause negative consequences affecting finances, work/study, physical and mental health, relationships, law abidingness, and the community. Although existing measures enable investigations of gambling harms, there is still a need for a brief measure covering the full range of gambling related harms.</p></div><div><h3>Methods</h3><p>We validated a 7-item domain-general harm scale (DGHS-7) using data from a cross-sectional survey of United Kingdom residents reporting gambling within the last 12 months (<em>n</em> = 2558, 62.4% women, mean age 40.1 years (<em>SD</em> = 12.5)). The DGHS-7 was investigated in terms of factor structure, measurement invariance, and convergent validity with a comprehensive 72-item checklist of gambling harm, the Short Gambling Harms Screen (SGHS), and the Problem Gambling Severity Index (PGSI). Discriminative validity was checked against the Personal Wellbeing Index (PWI). Internal consistency was also calculated.</p></div><div><h3>Results</h3><p>Confirmatory factor analysis supported a one-factor solution (χ² = 136.991, <em>df</em> = 14, χ²/<em>df</em> = 9.785, <em>p</em> &lt;.001, CFI = 0.999, RMSEA = 0.059, 90% CI [0.050, 0.068]). Measurement invariance was supported for gender and binary categorization of age and income (ΔCFI = 0.001). The DGHS-7 correlated strongly with the 72-item checklist (<em>r_s</em> = 0.824), the SGHS (<em>r_s</em> = 0.793), the PGSI (<em>r_s</em> = 0.768), and moderately with the PWI (<em>r_s</em> = -0.303). Cronbach’s alpha = 0.91 and ordinal alpha = 0.96 indicated good internal consistency.</p></div><div><h3>Conclusions</h3><p>Psychometric support was found for a brief measure covering all recognized domains of gambling harm. The DGHS-7 is useful for researchers needing a generic and short measure for epidemiological and other studies calling for short scales.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"17 ","pages":"Article 100499"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10088494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived parental alcohol problems and psychosomatic complaints among adolescents in Sweden","authors":"Numan Raza Syed ,&nbsp;Joakim Wahlström ,&nbsp;Sara Brolin Låftman ,&nbsp;Johan Svensson","doi":"10.1016/j.abrep.2023.100491","DOIUrl":"10.1016/j.abrep.2023.100491","url":null,"abstract":"<div><h3>Introduction</h3><p>For adolescents, parental problem drinking can be regarded as a chronic stressor, negatively affecting their health. There is limited knowledge and a relative lack of empirical evidence on this topic, especially in Sweden. The aim of the current study was to examine perceived parental alcohol problems and the links with psychosomatic complaints among adolescents in Sweden.</p></div><div><h3>Methods</h3><p>Data were obtained from the Swedish Council for Information on Alcohol and Other Drugs’ national survey of 2021, collected amongst 9,032 students in grades 9 (∼15–16 years) and 11 (∼17–18 years). Perceived parental alcohol problems were measured by the Children of Alcoholics Screening Test (CAST-6) scale, using a cutoff at ≥ 3. Psychosomatic complaints were captured by a binary measure based on the frequency of headache, stomach ache, feeling depressed or down, difficulties to fall asleep, and sleeping poorly at night. Sociodemographic characteristics included gender, grade, parental education, and parental country of birth. Descriptive analyses with chi2 tests and binary logistic regression analyses were performed.</p></div><div><h3>Results</h3><p>Adolescents with perceived parental alcohol problems had higher odds of reporting psychosomatic complaints compared with adolescents without perceived parental drinking problems, even when adjusting for sociodemographic characteristics. Girls, grade 11 students, adolescent with at least one parent born in Sweden, and those without university-educated parents were more likely to report parental alcohol problems.</p></div><div><h3>Conclusions</h3><p>The findings highlight adolescents with perceived parental alcohol problems need support. The school, being an arena where adolescents spend much of their time, may play a vital role in this regard.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"17 ","pages":"Article 100491"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social media use and abuse: Different profiles of users and their associations with addictive behaviours","authors":"Deon Tullett-Prado ,&nbsp;Vasileios Stavropoulos ,&nbsp;Rapson Gomez ,&nbsp;Jo Doley","doi":"10.1016/j.abrep.2023.100479","DOIUrl":"10.1016/j.abrep.2023.100479","url":null,"abstract":"<div><h3>Introduction</h3><p>Social media use has become increasingly prevalent worldwide. Simultaneously, concerns surrounding social media abuse/problematic use, which resembles behavioural and substance addictions, have proliferated. This has prompted the introduction of ‘Social Media Addiction’ [SMA], as a condition requiring clarifications regarding its definition, assessment and associations with other addictions. Thus, this study aimed to: (a) advance knowledge on the typology/structure of SMA symptoms experienced and: (b) explore the association of these typologies with addictive behaviours related to gaming, gambling, alcohol, smoking, drug abuse, sex (including porn), shopping, internet use, and exercise.</p></div><div><h3>Methods</h3><p>A sample of 968 [Mage = 29.5, SDage = 9.36, nmales = 622 (64.3 %), nfemales = 315, (32.5 %)] adults was surveyed regarding their SMA experiences, using the Bergen Social Media Addiction Scale (BSMAS). Their experiences of Gaming, Internet, Gambling, Alcohol, Cigarette, Drug, Sex, Shopping and Exercise addictions were additionally assessed, and latent profile analysis (LPA) was implemented.</p></div><div><h3>Results</h3><p>Three distinct profiles were revealed, based on the severity of one’s SMA symptoms: ‘low’, ‘moderate’ and ‘high’ risk. Subsequent ANOVA analyses suggested that participants classified as ‘high’ risk indicated significantly higher behaviours related to internet, gambling, gaming, sex and in particular shopping addictions.</p></div><div><h3>Conclusions</h3><p>Results support SMA as a unitary construct, while they potentially challenge the distinction between technological and behavioural addictions. Findings also imply that the assessment of those presenting with SMA behaviours, as well as prevention and intervention targeting SMA at risk groups, should consider other comorbid addictions.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"17 ","pages":"Article 100479"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cluster analysis to identify patient profiles and substance use patterns among pregnant persons with opioid use disorder","authors":"Elizabeth Charron ,&nbsp;Ziji Yu ,&nbsp;Brad Lundahl ,&nbsp;John Silipigni ,&nbsp;Akiko Okifuji ,&nbsp;Adam J. Gordon ,&nbsp;Jacob D. Baylis ,&nbsp;Ashley White ,&nbsp;Kristi Carlston ,&nbsp;Walitta Abdullah ,&nbsp;Benjamin Haaland ,&nbsp;Elizabeth E. Krans ,&nbsp;Marcela C. Smid ,&nbsp;Gerald Cochran","doi":"10.1016/j.abrep.2023.100484","DOIUrl":"10.1016/j.abrep.2023.100484","url":null,"abstract":"<div><p>The study objective was to identify distinct profiles of pregnant persons with opioid use disorder (PP-OUD) using cluster analysis and examine difference in substance use patterns between profiles. We examined data from 104 PP-OUD ≤ 32 weeks of gestation who were recruited into a behavioral health clinical trial at two academic medical centers. We used Partitioning Around Medoids analysis to identify clusters and explored patterns of substance use and substance use treatment between clusters using bivariate statistical tests and regression methods. We identified two distinct clusters of participants, including ‘Group A’ (n = 68; 65.4 %) and ‘Group B’ (n = 36; 34.6 %). Group A had fewer members who were not employed (38 % vs 58 %) and incarcerated (3 % vs 8 %) compared to Group B. Group A compared with Group B included more members with: a history of overdose (72 % vs 50 %); anxiety (85 % vs 25 %); ≥moderate pain (76 % vs 22 %); ≥moderate depression (75 % vs 36 %); ≥moderate drug use severity (94 % vs 78 %); and, more days of cannabis (mean: 6.2 vs 2.3 days), stimulant (mean: 4.5 vs 1.3 days), and injection heroin (mean: 1.3 vs 0 days) use in the past 30 days (<em>P</em> &lt; 0.05 for all comparisons). Clusters of PP-OUD differed with respect to sociodemographic characteristics, mental health conditions, and substance use patterns. More research is needed to confirm identified profiles and assess treatment outcomes associated with cluster membership.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"17 ","pages":"Article 100484"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/d7/main.PMC9950438.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10793193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in daily dose in open-label compared to double-blind: The role of clients’ expectations in injectable opioid agonist treatment","authors":"Sarin Blawatt ,&nbsp;Lourdes Atziri Gonzalez Arreola ,&nbsp;Tianna Magel ,&nbsp;Scott MacDonald ,&nbsp;Scott Harrison ,&nbsp;Martin T. Schechter ,&nbsp;Eugenia Oviedo-Joekes","doi":"10.1016/j.abrep.2023.100490","DOIUrl":"10.1016/j.abrep.2023.100490","url":null,"abstract":"<div><h3>Introduction</h3><p>Though double-blind studies have indicated that hydromorphone and diacetylmorphine produce similar effects when administered through injectable opioid agonist treatment (iOAT) programs, participant preference<!--> <!-->may influence some aspects of medication dispensation such as dose.</p></div><div><h3>Methods</h3><p> <!-->This is a retrospective longitudinal analysis. Participants (n = 131) were previously enrolled in a double-blind clinical trial for iOAT who continued to receive treatment in an open-label follow up study. Data included<!--> <!-->medication dispensation records from 2012 to 2020. Using linear regression and paired t-tests, average daily dose totals of hydromorphone and diacetylmorphine were examined comparatively between double-blind and open-label periods. A subgroup analysis explored dose difference by preference using the proxy, blinding guess, a variable used to facilitate the measurement of treatment masking during the clinical trial by asking which medication the participant thought they received.</p></div><div><h3>Results</h3><p>During the open-label period, participants prescribed diacetylmorphine received<!--> <!-->49.5 mg less than during the double-blind period (95% CI −12.6,-86.4).<!--> <!-->Participants receiving hydromorphone did not see a significant dose decrease. Participants who guessed they received hydromorphone during the clinical trial, but learned they<!--> <!-->were on diacetylmorphine during the open-label period, saw a<!--> <!-->decrease in total daily dose of 78.3 mg less (95% CI −134.3,–22.4) during the open-label period.</p></div><div><h3>Conclusion</h3><p>If client preference is considered<!--> <!-->in the treatment of chronic opioid use disorder, clients may be able to better moderate their dose to suit their individual needs. Together with their healthcare providers, clients<!--> <!-->can participate in their treatment trajectories collaboratively to optimize client outcomes and promote person-centered<!--> <!-->treatment options.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"17 ","pages":"Article 100490"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/02/04/main.PMC10140796.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9746679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}