Edward R. Cachay , Tesfaye S. Moges , Huifang Qin , Laura Bamford , David J. Grelotti , Wm. Christopher Mathews
{"title":"Effects of drug and hazardous alcohol use on having a detectable HIV viral load: An adherence mediation analysis","authors":"Edward R. Cachay , Tesfaye S. Moges , Huifang Qin , Laura Bamford , David J. Grelotti , Wm. Christopher Mathews","doi":"10.1016/j.abrep.2023.100486","DOIUrl":"10.1016/j.abrep.2023.100486","url":null,"abstract":"<div><h3>Objectives</h3><p>People living with HIV (PWH) with substance or alcohol use often have unsuppressed plasma HIV viral loads (pVL). The degree to which substance and alcohol use effects on HIV viral suppression are mediated through medication nonadherence is incompletely understood.</p></div><div><h3>Methods</h3><p>We included PWH prescribed antiretroviral therapy and receiving care at an academic HIV clinic between 2014 and 2018 who completed both patient-reported outcomes (PRO) questionnaires and had subsequent pVL measurements. Measures included assessments of alcohol use (AUDIT-C), drug use (NIDA-ASSIST), and self-reported adherence measured using four different methods. Substances found in bivariate analysis to predict detectable pVL were modeled separately for mediation effects through adherence. We report natural direct (NDE) and indirect effect (NIE), marginal total effect (MTE), and percentage mediated.</p></div><div><h3>Results</h3><p>Among 3125 PWH who met eligibility criteria, 25.8% reported hazardous alcohol use, 27.1% cannabis, 13.1% amphetamines, 1.9% inhalants, 5.3% cocaine, 4.5% sedative-hypnotics, 2.9% opioids, and 2.3% hallucinogens. Excellent adherence was reported by 58% of PWH, and 10% had detectable pVL. Except for sedatives, using other substances was significantly associated with worse adherence. Bivariate predictors of detectable pVL were [OR (95% CI)]: amphetamine use 2.4 (1.8–3.2) and opioid use 2.3 (1.3–4.0). The percent of marginal total effect mediated by nonadherence varied by substance: 36% for amphetamine use, 27% for opioid use, and 39% for polysubstance use.</p></div><div><h3>Conclusion</h3><p>Use of amphetamines, opioids, and multiple substances predicted detectable pVL. Up to 40% of their effects were mediated by self-reported nonadherence. Confirmation using longitudinal measurement models will strengthen causal inference from this cross-sectional analysis.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9168239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Negative urgency, PTSD symptoms, and alcohol risk in college students","authors":"Hagar Hallihan , Hanaan Bing-Canar , Katherine Paltell , Erin C. Berenz","doi":"10.1016/j.abrep.2023.100480","DOIUrl":"10.1016/j.abrep.2023.100480","url":null,"abstract":"<div><h3>Introduction</h3><p>Theoretical models of trauma and alcohol use suggest that trauma-exposed individuals with higher levels of PTSD symptoms are at increased risk of problematic and coping-oriented alcohol use to alleviate unwanted internal states. The goal of the current study was to evaluate whether these associations are enhanced among young adults who report engaging in impulsive behavior in the context of negative affect (i.e., high negative urgency). It was hypothesized that (a) higher negative urgency would be associated with problematic alcohol use; and that (b) negative urgency would moderate the association between PTSD symptoms and problematic alcohol use. <strong>Methods:</strong> This study<!--> <!-->used a<!--> <!-->cross-sectional, secondary data analysis<!--> <!-->design run on 213 participants: college students, ages 18–25, who endorsed both having an interpersonal traumatic event and current weekly alcohol use. Participants completed a series of assessments and self-report questionnaires. <strong>Results:</strong> Results of hierarchical linear regression models indicated that greater negative urgency was significantly associated with greater negative alcohol-related consequences and greater coping motives for alcohol, but not past 30-day binge frequency or past 30-day alcohol quantity. Negative urgency did not moderate associations between PTSD symptoms and alcohol outcomes. <strong>Conclusions:</strong> PTSD symptoms and negative urgency are uniquely associated with indices of alcohol risk in college students with a history of trauma exposure. However, individuals high in negative urgency are not necessarily consuming more alcohol, nor does negative urgency increase the association between PTSD symptoms and drinking outcomes in this population.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/94/main.PMC9868323.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10620504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Livia Pischiutta , Marco Garzitto , Giuliano Zamparutti , Enrico Moratti , Umberto Albert , Marco Colizzi , Matteo Balestrieri
{"title":"Mentalization in young patients undergoing opioid agonist treatment: Implications for clinical management","authors":"Livia Pischiutta , Marco Garzitto , Giuliano Zamparutti , Enrico Moratti , Umberto Albert , Marco Colizzi , Matteo Balestrieri","doi":"10.1016/j.abrep.2023.100497","DOIUrl":"10.1016/j.abrep.2023.100497","url":null,"abstract":"<div><h3>Background</h3><p>Mentalization is the ability to use internal mental states to manage and understand one’s own and others’ behavior. Inefficient mentalization has been associated to poor neuropsychological outcomes, including substance use disorder (SUD) and addiction. However, studies primarily investigating mentalization in SUD are lacking.</p></div><div><h3>Methods</h3><p>Using the Reflective Functioning Questionnaire (RFQ), the Measurements in the Addictions for Triage and Evaluation, version 2.1 (MATE-IT-2.1), and the Mini International Neuropsychiatric Interview, 7th edition (MINI-7), an outpatient assessment investigated inefficient mentalization (i.e., ‘hypo-mentalization’ or ‘uncertainty’: concrete thinking with poor attribution of mental states; ‘hyper-mentalization’ or ‘certainty’: rigid and biased attribution of mental states) and socio-demographic and clinical characteristics, including SUD-related symptoms and any other psychiatric comorbidity, among opioid addiction (OA) patients in Opioid Agonist Treatment (OAT).</p></div><div><h3>Results</h3><p>Thirty-seven consecutive OA patients in OAT (female, 45.9 %; age, M ± SD, 24.3 ± 3.55) were recruited. Patients’ mentalization differed from normative data, in terms of higher uncertainty and lower certainty scores. Also, higher uncertainty score was found among younger patients and in those with the most severe SUD in terms of craving and need for care. Finally, lower certainty score was found in those with a more severe substance abuse, previous contacts with pediatric mental-health services, and receiving a therapeutic community support.</p></div><div><h3>Conclusions</h3><p>OA patients with inefficient mentalization present with a higher burden in terms of SUD severity, comorbidities, psychosocial disabilities, and service use, with important public health implications. Interventions targeting mentalization may have positive repercussions in preventing SUD, mitigating its severity, and containing its healthcare and social costs.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9546459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum regarding missing Declaration of Competing Interest statements in previously published articles","authors":"","doi":"10.1016/j.abrep.2022.100474","DOIUrl":"10.1016/j.abrep.2022.100474","url":null,"abstract":"","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293920/pdf/main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bartosz Kowalik , Paul H. Delfabbro , Daniel L. King
{"title":"Impaired control over gaming scale (ICOGS): Development, confirmatory factor validation, and psychometric evaluation","authors":"Bartosz Kowalik , Paul H. Delfabbro , Daniel L. King","doi":"10.1016/j.abrep.2023.100489","DOIUrl":"10.1016/j.abrep.2023.100489","url":null,"abstract":"<div><h3>Background and aims</h3><p>The concept of impaired control is central to addictive disorders, including gaming disorder in the DSM-5 and ICD-11. Impaired control refers to the recurrent inability to resist impulses to engage in certain activities or behaviours and the failure to limit or stop this engagement. Although numerous screening tools for gaming disorder symptoms have been developed, these instruments have limited capacity for measuring the nature and extent of impaired control. To address this limitation, the present study reports on the creation of the Impaired Control Over Gaming Scale (ICOGS), an 8-item screening tool to assess gaming-related impaired control.</p></div><div><h3>Methods</h3><p>A total of 513 gamers, including 125 gamers (24.3%) who met the DSM-5 criteria for gaming disorder, were recruited from <em>Prolific,</em> an online crowd-sourcing platform.</p></div><div><h3>Results</h3><p>The ICOGS demonstrated promising psychometric properties. Exploratory and confirmatory factor analysis using two samples provided robust support for a 2-factor model and high internal consistency of the scale. ICOGS scores were significantly and positively associated with gaming disorder symptoms, gaming-related harms, gaming frequency, psychological distress, and neuroticism. Using receiver operating characteristic analysis, the ICOGS differentiated between non-problem gamers and those who met the criteria for GD.</p></div><div><h3>Discussion and conclusions</h3><p>Overall, the ICOGS appears to be a valid and reliable scale for use in studies of problem gaming, and may be useful for assessing outcomes of GD interventions that employ self-regulation and stopping techniques to reduce or eliminate problem gaming behavior.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105481/pdf/main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9323840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magaly Brodeur, Sophie Audette-Chapdelaine, Nicolas Lavoie, Cyril Devault-Tousignant, Anne-Marie Auger, Adèle Morvannou, Andrée-Anne Légaré, Eva Monson, Didier Jutras-Aswad, Catherine Hudon
{"title":"A call for qualitative and mixed-methods research on gambling and cannabis","authors":"Magaly Brodeur, Sophie Audette-Chapdelaine, Nicolas Lavoie, Cyril Devault-Tousignant, Anne-Marie Auger, Adèle Morvannou, Andrée-Anne Légaré, Eva Monson, Didier Jutras-Aswad, Catherine Hudon","doi":"10.1016/j.abrep.2023.100494","DOIUrl":"10.1016/j.abrep.2023.100494","url":null,"abstract":"<div><p>Gambling disorder and cannabis use disorder are both considered major public health issues. Despite the well-documented frequency of substance use disorders among people with gambling disorder, little is known about the experiences of those who both engage with gambling and cannabis. A scoping review was undertaken to investigate studies focusing on the experiences of people who gamble and use cannabis. Unexpectedly, no qualitative or mixed-methods studies that included an in-depth qualitative component to study the lived experiences of this population were found. This absence highlights the critical need to diversify research methods and fill the gap in knowledge of the lived experiences of people who both gamble and consume cannabis.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/4b/main.PMC10189349.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9868955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Orrin D. Ware , Paul Sacco , John G. Cagle , Jodi J. Frey , Fernando A. Wagner , Alexandra S. Wimberly , Bernard Gyebi-Foster , Mayra Diaz , Kisun Peters , Sarah E. Zemore
{"title":"Higher perceived stress during admission is associated with shorter retention in short-term residential substance use disorder treatment","authors":"Orrin D. Ware , Paul Sacco , John G. Cagle , Jodi J. Frey , Fernando A. Wagner , Alexandra S. Wimberly , Bernard Gyebi-Foster , Mayra Diaz , Kisun Peters , Sarah E. Zemore","doi":"10.1016/j.abrep.2023.100502","DOIUrl":"https://doi.org/10.1016/j.abrep.2023.100502","url":null,"abstract":"","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49776514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors affecting tobacco, nicotine, and cannabis product use among California young adults during the COVID-19 pandemic: A qualitative study","authors":"Joshua S. Yang , Claudia Pacheco , Tim K. Mackey","doi":"10.1016/j.abrep.2022.100470","DOIUrl":"10.1016/j.abrep.2022.100470","url":null,"abstract":"<div><p>The effects of COVID-19 on tobacco and cannabis use have been variable, and it is unclear the extent to which factors affecting changes in tobacco and cannabis use differ. The purpose of this study was to identify the COVID-19-related factors that affect changes in tobacco and cannabis use during the pandemic. Focus groups with 114 young adults in California in April 2021 were held to discuss tobacco and cannabis use patterns, adverse events, and the effect of COVID-19 on tobacco and cannabis product use. Factors affecting changes in use were largely similar between tobacco products and cannabis products. Increases in product use were a result of changing social environment, coping with emotional and psychological distress, and product related factors. Decreases in product use were a result of social isolation, COVID-19-related health concerns, disruptions in daily patterns of living, and reduced access. Drivers of increased cannabis use distinct from tobacco or nicotine product use included feeling greater freedom to disengage and perceptions of less harm. Improved understanding of how the pandemic has affected tobacco and cannabis use can inform tailored interventions to both support those who have decreased or quit and assist those who have increased use during the pandemic to reduce or cease their consumption.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/e0/main.PMC9661417.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40698205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"‘A circuit breaker’ – Interrupting the alcohol autopilot: A qualitative exploration of participants’ experiences of a personalised mHealth approach bias modification intervention for alcohol use","authors":"G.L. Bolt, H. Piercy, A. Barnett, V. Manning","doi":"10.1016/j.abrep.2022.100471","DOIUrl":"10.1016/j.abrep.2022.100471","url":null,"abstract":"<div><h3>Objective</h3><p>There is a need for low-cost, wide-reaching interventions to enhance accessibility of support for people with hazardous alcohol consumption. We assessed participant experiences of using a novel, personalised mHealth intervention offering approach bias modification (ApBM) for alcohol use in a community sample drinking at harmful levels to enable a deeper understanding of the end user and engagement.</p></div><div><h3>Methods</h3><p>Eighteen semi-structured telephone interviews were conducted with adults in the community drinking at harmful/hazardous levels. A reflexive thematic analysis approach was used and data analysis followed iterative categorisation.</p></div><div><h3>Results</h3><p>Engagement/Motivation and Clinical Value were overarching themes. The useable, accessible, customisable design described by participants enabled training to be readily integrated into routines, enhancing autonomy and self-efficacy beliefs, and facilitating engagement/motivation. Where autonomy or perceived self-efficacy were threatened by a rigid training schedule or lack of clarity/reminders, engagement was reduced. Training increased awareness of drinking behaviours, and encouraged participants to consider alternate goal-directed behaviours with feedback suggesting training may function as a ‘circuit breaker’, increasing time between alcohol craving and seeking, and enabling reflective processing, at least in the short term.</p></div><div><h3>Conclusions</h3><p>This novel smartphone intervention for alcohol use may be a useful, accessible, ‘just in time’ adjunctive support tool for non-treatment seekers, meeting an important gap in the field. Findings have implications for the implementation of subsequent digital interventions, suggesting participants may stand to gain more from an intervention which enables autonomy and improves self-efficacy beliefs. Theoretically, findings speak to the role of inferential processing in behaviour change, but further research is needed to clearly elucidate ApBM training mechanisms. Practical recommendations for subsequent app iterations are suggested, along with additional opportunities worthy of consideration for future initiatives.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/97/main.PMC9682330.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40722759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia Folpmers , Dennis O Mook-Kanamori , Renée de Mutsert , Frits R. Rosendaal , Ko Willems van Dijk , Diana van Heemst , Raymond Noordam , Saskia le Cessie
{"title":"Agreement between nicotine metabolites in blood and self-reported smoking status: The Netherlands Epidemiology of Obesity study","authors":"Sofia Folpmers , Dennis O Mook-Kanamori , Renée de Mutsert , Frits R. Rosendaal , Ko Willems van Dijk , Diana van Heemst , Raymond Noordam , Saskia le Cessie","doi":"10.1016/j.abrep.2022.100457","DOIUrl":"10.1016/j.abrep.2022.100457","url":null,"abstract":"<div><h3>Introduction</h3><p>Self-report and nicotine detection are methods to measure smoking exposure and can both lead to misclassification. It is important to highlight discrepancies between these two methods in the context of epidemiological research.</p></div><div><h3>Objective</h3><p>The aim of this cross-sectional study is to assess the agreements between self-reported smoking status and nicotine metabolite detection.</p></div><div><h3>Methods</h3><p>Data of 599 participants from the Netherlands Epidemiology of Obesity study were used to compare serum metabolite levels of five nicotine metabolites (cotinine, hydroxy-cotinine, cotinine <em>N</em>-Oxide, norcotinine, 3-hydroxy-cotinine-glucuronide) between self-reported never smokers (n = 245), former smokers (n = 283) and current smokers (n = 71). We assessed whether metabolites were absent or present and used logistic regression to discriminate between current and never smokers based on nicotine metabolite information. A classification tree was derived to classify individuals into current smokers and non/former smokers based on metabolite information.</p></div><div><h3>Results</h3><p>In 94% of the self-reported current smokers, at least one metabolite was present, versus in 19% of the former smokers and in 10% of the never smokers. In none of the never smokers, cotinine-<em>n</em>-oxide, 3-hydroxy-cotinine-<em>n</em>-glucorinide or norcotinine was present, while at least one of these metabolites was detected in 68% of the self-reported current smokers. The classification tree classified 95% of the participants in accordance to their self-reported smoking status. All self-reported smokers who were classified as non-smokers according to the metabolite profile, had reported to be occasional smokers.</p></div><div><h3>Conclusion</h3><p>The agreement between self-reported smoking status and metabolite information was high. This indicates that self-reported smoking status is generally reliable.</p></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40392241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}