Dementia and Geriatric Cognitive Disorders Extra最新文献

{"title":"Prediction of Postoperative Delirium after Gastrointestinal Surgery Using the Mie Constructional Apraxia Scale.","authors":"Yosuke Tenpaku,&nbsp;Masayuki Satoh,&nbsp;Kenji Kato,&nbsp;Kazuhisa Fujinaga,&nbsp;Yuji Haruki,&nbsp;Hiroki Nakahashi,&nbsp;Keisuke Morikawa,&nbsp;Yasunori Imaoka,&nbsp;Hiroyuki Takemura,&nbsp;Hiroshi Tatsumi","doi":"10.1159/000520249","DOIUrl":"https://doi.org/10.1159/000520249","url":null,"abstract":"<p><strong>Background: </strong>Postoperative delirium (POD) is a transient postoperative complication that occurs after surgical procedures. Risk factors reported for POD include dementia and cognitive decline. The purpose of this study was to identify predictors of POD by examining the use of preoperative neuropsychological tests, including the Mie Constructional Apraxia Scale (MCAS), and patient background factors.</p><p><strong>Method: </strong>The study was performed as a retrospective cohort study. The subjects were 33 patients (mean age, 75.8 ± 10.9 years; male:female ratio, 26:7) who underwent gastrointestinal surgery at Matsusaka City Hospital between December 2019 and April 2021. Data were collected retrospectively from medical records. The study was started after receiving approval from the institution's ethics committee. The survey items included general patient information, nutritional assessment, surgical information, and neuropsychological tests. Subjects were classified into 2 groups according to the presence or absence of POD. If a significant difference was observed between the 2 groups, the sensitivity, specificity, and area under the curve were calculated using a receiver operating characteristic (ROC) curve.</p><p><strong>Result: </strong>There were 10 patients in the POD group (male:female ratio, 6:4) and 23 patients in the non-POD group (20:3). The POD group had a shorter education history (<i>p</i> = 0.047) and significantly higher MCAS scores (<i>p</i> = 0.007) than the non-POD group. The ROC curve showed a sensitivity of 90%, a specificity of 69%, and an area under the curve of 0.798 when the MCAS cutoff value was set at 3 points.</p><p><strong>Conclusion: </strong>Preoperative MCAS results were capable of predicting the occurrence of POD after gastrointestinal surgery. In addition, a relatively short education background was also considered a risk factor for POD.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"306-313"},"PeriodicalIF":2.3,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/12/dee-0011-0306.PMC8740234.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39862102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Year Change in Locus of Control among People with Dementia.","authors":"Ingeborg Halse, Guro Hanevold Bjørkløf, Knut Engedal, Geir Selbæk, Maria Lage Barca","doi":"10.1159/000520248","DOIUrl":"10.1159/000520248","url":null,"abstract":"<p><strong>Introduction: </strong>Knowledge of how perceptions of personal control change over time may provide valuable insights into how people cope with having dementia. The present study aimed to examine change in locus of control over a 12-month period in persons with dementia.</p><p><strong>Method: </strong>The study included 52 participants with dementia. Locus of control was measured with the Locus of Control of Behavior Scale (LoCB), with higher scores indicating a more external locus of control, interpreted as perceiving less personal control. A ≥5% change on the LoCB was considered clinically meaningful. We recorded sociodemographic characteristics and assessed dementia severity, cognition, ability to function independently in daily activities and physical self-maintenance, depressive symptomatology, and number of prescribed medications. Analyses were performed to examine differences between those with increases (more external) or decreases (less external) in the LoCB score after 12 months and to examine associations between baseline variables and change in the LoCB score.</p><p><strong>Results: </strong>The mean LoCB score for the total sample did not change after 12 months (baseline mean 29.33 vs. follow-up mean 30.33, <i>p</i> = 0.553); however, 2 subgroups emerged. Using the ≥5% cutoff revealed that the LoCB score changed for 92.3% of the sample, becoming less external (lower LoCB) for 21 participants and more external (higher LoCB) for 27 participants. At baseline, the mean LoBC score was higher in the group that became less external (33.81 vs. 24.56), <i>p</i> = 0.006, while this was reverse at follow-up (23.57 vs. 34.41), <i>p</i> = 0.001. Dementia severity and dependence in physical self-maintenance increased during the 12 months in both groups. Among those becoming more external, we also found a decline in cognition (<i>p</i> = 0.002), an increase in dependence in daily activities (<i>p</i> = 0.003), an increase in the use of prescribed medication, and a decrease in depressive symptomatology (<i>p</i> = 0.003). The baseline LoCB score was the only variable associated with 12-month change in LoCB scores (<i>p</i> = 0.001).</p><p><strong>Conclusion: </strong>Most participants showed a clinically meaningful change in locus of control after 12 months. Those with more signs of dementia progression reported a decrease in personal control but also a decrease in depressive symptoms. These findings are interesting for our understanding of coping but must be replicated with a larger sample.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"298-305"},"PeriodicalIF":2.3,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/de/dee-0011-0298.PMC8739984.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and Safety of Aromatherapy in Managing Behavioral and Psychological Symptoms of Dementia: A Mixed-Methods Systematic Review.","authors":"Becky Siu Yin Li,&nbsp;Carmen Wing Han Chan,&nbsp;Minjie Li,&nbsp;Irene Kit Yee Wong,&nbsp;Yvonne Hoi Un Yu","doi":"10.1159/000519915","DOIUrl":"10.1159/000519915","url":null,"abstract":"<p><strong>Introduction: </strong>Behavioral and psychological symptoms of dementia (BPSD) is the most prominent and distressing manifestation for older persons with dementia (PWD) and caregivers. Aromatherapy has demonstrated its effectiveness in managing BPSD in various studies. However, previous studies and systematic reviews have obtained inconsistent findings, and a review of qualitative studies is yet to be conducted.</p><p><strong>Method: </strong>A mixed-methods systematic review with a convergent segregated approach was performed to evaluate the effectiveness of aromatherapy in improving the BPSD and quality of life (QoL) of PWD and in relieving the distress and burden of caregivers, as well as its safety for PWD. Both published and unpublished quantitative and qualitative studies written in English and Chinese between January 1996 and December 2020 were retrieved from 28 databases, including MEDLINE, EMBASE, and Web of Science, based on the prespecified criteria. The methodological quality was assessed by using critical appraisal tools from the Joanna Briggs Institute. Quantitative synthesis, qualitative synthesis, and integration of quantitative and qualitative evidence were performed.</p><p><strong>Results: </strong>A total of 12 randomized controlled trials, 10 quasi-experimental studies, and 2 qualitative studies were included in the review. Some inconsistent findings regarding the effectiveness of aromatherapy in reducing the severity of BPSD were observed. Some studies reported that aromatherapy significantly improved the QoL of PWD and relieved the distress and burden of caregivers, promoted a positive experience among caregivers, and had very low adverse effects on PWD (with aromatherapy inhalation reporting no adverse effects).</p><p><strong>Conclusion: </strong>Aromatherapy, especially in the inhalation approach, could be a potentially safe and effective strategy for managing BPSD. However, more structuralized and comparable studies with sufficient sample size, adherence monitoring, and sound theoretical basis could be conducted to obtain conclusive findings.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"273-297"},"PeriodicalIF":2.3,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/76/34/dee-0011-0273.PMC8739377.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Plasma Donepezil Concentration on Behavioral and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease.","authors":"Yoshiyuki Kagawa,&nbsp;Yoshiaki Yamamoto,&nbsp;Ayami Ueno,&nbsp;Kengo Inomata,&nbsp;Mayu Tezuka,&nbsp;Takashi Osawa,&nbsp;Yasuharu Yazawa,&nbsp;Toshio Maeda,&nbsp;Tomokazu Obi","doi":"10.1159/000516938","DOIUrl":"https://doi.org/10.1159/000516938","url":null,"abstract":"<p><strong>Background/aims: </strong>The behavioral and psychological symptoms of dementia (BPSD) detract from the quality of life of not only dementia patients but also their family members and caregivers. Donepezil is used to treat Alzheimer's disease and is metabolized via cytochrome P450 (CYP) 2D6 and CYP3A4/5. It is controversial whether donepezil improves or exacerbates BPSD. This study investigated the relationships among BPSD, the pharmacokinetics of donepezil including its metabolite, 6-O-desmethyl donepezil, genetic polymorphisms of CYPs and P-glycoprotein, and patient backgrounds in 52 patients with Alzheimer's disease.</p><p><strong>Methods: </strong>BPSD were assessed using the Neuropsychiatric Inventory (NPI), with scores ≥20 points defined as severe BPSD. Plasma donepezil and 6-O-desmethyl donepezil concentrations were measured using liquid chromatography-tandem mass spectrometry.</p><p><strong>Results: </strong>Although significant relationships between NPI scores and plasma donepezil concentrations were not seen, none of the 15 patients (29%) with high plasma donepezil concentrations (≥60 ng/mL) developed severe BPSD. Polymorphisms of <i>CYP2D6</i>, <i>CYP3A5</i>, and <i>ABCB1</i> did not influence NPI scores. There were no significant relationships between NPI and patient background factors such as dosing regimen, concomitant use of other drugs, or laboratory test results. Two patients who underwent multiple blood samplings over 2 years showed an inverse correlation between plasma donepezil concentrations and NPI scores.</p><p><strong>Discussion/conclusions: </strong>These results indicate that higher plasma concentrations of donepezil contribute to preventing or alleviating rather than developing or deteriorating BPSD.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"264-272"},"PeriodicalIF":2.3,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8a/8f/dee-0011-0264.PMC8739384.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Survey of Dementia Knowledge and Recognition of Dementia Prevention and Practice in Healthy Older Adults.","authors":"Nanako Yamane,&nbsp;Kanto Tsukagoshi,&nbsp;Miharu Hisada,&nbsp;Mina Yamaguchi,&nbsp;Yukiko Suzuki","doi":"10.1159/000519513","DOIUrl":"https://doi.org/10.1159/000519513","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to investigate the level of dementia knowledge and behaviors recognized as dementia-preventive and the practice thereof among healthy older adults who are highly motivated to engage in activities.</p><p><strong>Methods: </strong>The participants were older adults registered at the Silver Human Resource Center of city A, and participants anonymously filled questionnaires through the aggregation method in January 2020.</p><p><strong>Results: </strong>The analysis included 78 participants (the effective response rate was 49.7%). All participants were aware of at least 4 dementia-preventive behaviors, and about 80% of all participants practiced at least 1 preventive behavior. Approximately 20% of participants were not practicing preventive behaviors at all. The elderly aged 65 to 74 years had more knowledge about dementia and more types of behavior perceived as dementia-preventive than the elderly aged 75 years and older. There was no significant correlation between the level of dementia knowledge and the number of types of dementia-preventive behaviors.</p><p><strong>Conclusions: </strong>Healthy older adults were aware of numerous behaviors for dementia prevention, and most older adults practiced preventive behaviors. In contrast, even with a high amount of knowledge about dementia, a small number of healthy older adults did not translate this knowledge into preventative behavioral practices. High levels of dementia knowledge do not translate into preventive behavioral practices.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"256-263"},"PeriodicalIF":2.3,"publicationDate":"2021-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/63/26/dee-0011-0256.PMC8739939.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Are the Key Points of Treatment for Cases of Mild Cognitive Impairment? Based on the Evaluation of Cognitive Function Tasks in the ADASJcog.","authors":"Yoshihiko Yoshii,&nbsp;Akiko Takahashi,&nbsp;Miyuki Ishizawa","doi":"10.1159/000519765","DOIUrl":"https://doi.org/10.1159/000519765","url":null,"abstract":"<p><strong>Background/aims: </strong>The aims of this study were to identify the degree of atrophy of the hippocampus in image findings and which cognitive function items should be focused on when treating mild cognitive impairment.</p><p><strong>Methods: </strong>A total of 66 cases with mild cognitive impairment were included in the study over a 1.5-year observation period. MR images were used to assess hippocampal atrophy, and cognitive function was assessed by the ADASJcog test.</p><p><strong>Results: </strong>In the mild dementia group, there was a hierarchical difference in the 4 cognitive impairments in which each degree was significantly higher hierarchically. In the normally improved group, memory and act dysfunction was significantly improved, and in deteriorated cases, memory, orientation, and act dysfunction increased significantly. The normally improved group tended to have lighter hippocampal atrophy than the deteriorating group.</p><p><strong>Discussion: </strong>In early treatment of mild cognitive impairment, it is important to focus on which cognitive items to treat, but there are no reports that present them numerically. Because it is not clear, there may be a risk that dementia may progress due to stunned treatment. It became clear that it was meaningful to show it, and it was the orientation and act function.</p><p><strong>Conclusion: </strong>It was suggested that hippocampal atrophy should be kept within the normal range and that the key treatment was mainly to improve memory and act dysfunction without reducing orientation function.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"250-255"},"PeriodicalIF":2.3,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/1b/dee-0011-0250.PMC8739624.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short- and Long-Term Functional Connectivity Differences Associated with Alzheimer's Disease Progression.","authors":"Jaime D Mondragón,&nbsp;Ramesh Marapin,&nbsp;Peter Paul De Deyn,&nbsp;Natasha Maurits","doi":"10.1159/000518233","DOIUrl":"https://doi.org/10.1159/000518233","url":null,"abstract":"<p><strong>Introduction: </strong>Progression of amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD) is a clinical event with highly variable progression rates varying from 10-15% up to 30-34%. Functional connectivity (FC), the temporal similarity between spatially remote neurophysiological events, has previously been reported to differ between aMCI patients who progress to AD (pMCI) and those who do not (i.e., remain stable; sMCI). However, these reports had a short-term follow-up and do not provide insight into long-term AD progression.</p><p><strong>Methods: </strong>Seventy-nine participants with a baseline and 78 with a 12-month, 51 with a 24-month, and 22 with a +48-month follow-up resting-state fMRI with aMCI diagnosis from the Alzheimer's Disease Neuroimaging Initiative database were included. FC was assessed using the CONN toolbox. Local correlation and group independent component analysis were utilized to compare regional functional coupling and between-network FC, respectively, between sMCI and pMCI groups. Two-sample <i>t</i> tests were used to test for statistically significant differences between groups, and paired <i>t</i>-tests were used to assess cognitive changes over time.</p><p><strong>Results: </strong>All participants (i.e., 66 sMCI and 19 pMCI) had a baseline and a year follow-up fMRI scan. Progression from aMCI to AD occurred in 19 patients (10 at 12 months, 5 at 24 months, and 4 at >48 months), while 73 MCI patients remained cognitively stable (sMCI). The pMCI and sMCI cognitive profiles were different. More between-network FC than regional functional coupling differences were present between sMCI and pMCI patients. Activation in the salience network (SN) and the default mode network (DMN) was consistently different between sMCI and pMCI patients across time.</p><p><strong>Discussion: </strong>sMCI and pMCI patients have different cognitive and FC profiles. Only pMCI patients showed cognitive differences across time. The DMN and SN showed local correlation and between-network FC differences between the sMCI and pMCI patient groups at multiple moments in time.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"235-249"},"PeriodicalIF":2.3,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/8c/dee-0011-0235.PMC8543355.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotid Compliance and Parahippocampal and Hippocampal Volume over a 20-Year Period.","authors":"Hediyeh Baradaran, Alen Delic, J Scott McNally, Matthew Alexander, Jennifer J Majersik, Dennis L Parker, Adam de Havenon","doi":"10.1159/000518234","DOIUrl":"10.1159/000518234","url":null,"abstract":"<p><strong>Introduction: </strong>We evaluated the association between carotid compliance, a measure of arterial stiffness, to parahippocampal volume (PHV) and hippocampal volume (HV) over 20 years later in the Atherosclerosis Risk in the Community study.</p><p><strong>Methods: </strong>We included participants with common carotid compliance measurements at visit 1 (1987-1989) and volumetric brain MRI at visit 5 (2011-2013). The primary outcomes are pooled bilateral PHV and HV. We performed linear regression models adjusting for age, sex, vascular risk factors, and total brain volume.</p><p><strong>Results: </strong>Of the 614 participants, higher compliance was correlated with higher PHV (<i>R</i> = 0.218[0.144-0.291], <i>p</i> < 0.001) and HV (<i>R</i> = 0.181 [0.105-0.255, <i>p</i> < 0.001]). The association was linear and significant after adjusting for confounders. At follow-up MRI, 30 patients with dementia had lower PHV and HV than patients without dementia (<i>p</i> < 0.001 and <i>p</i> < 0.001, respectively).</p><p><strong>Conclusion: </strong>Carotid compliance is associated with higher PHV and HV when measured 20 years later, further supporting the link between arterial stiffness and cognitive decline.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"227-234"},"PeriodicalIF":1.4,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/e4/dee-0011-0227.PMC8543351.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Evaluation of the Behavioral and Psychological Symptoms of Dementia Questionnaire 13-Item Version (BPSD13Q).","authors":"Taiga Fuju,&nbsp;Tetsuya Yamagami,&nbsp;Mio Ito,&nbsp;Noriko Naito,&nbsp;Haruyasu Yamaguchi","doi":"10.1159/000518973","DOIUrl":"https://doi.org/10.1159/000518973","url":null,"abstract":"<p><strong>Introduction: </strong>Most behavioral and psychological symptoms of dementia (BPSD) scales have copyright issues and are difficult for care staff to use in daily care settings because they were primarily designed for physicians. Therefore, an easier tool for care staff is required. This study aimed to develop and validate the BPSD questionnaire 13-item version (BPSD13Q).</p><p><strong>Methods: </strong>We obtained data from 444 people with dementia living in group homes in Japan using the BPSD plus questionnaire (BPSD + Q; 27-item version) and Neuropsychiatric Inventory Nursing Home version (NPI-NH). We selected appropriate items to make a short-form version of the BPSD + Q and examined the construct validity, internal consistency, and criterion-related validity of the questionnaire.</p><p><strong>Results: </strong>By the pilot review, research on correlations with similar items from comparable scales, and factor analysis, we reduced 27 items to 13 items (BPSD13Q). The BPSD13Q and BPSD13Q-distress (BPSD13Q-D) showed good internal consistency (Cronbach's α = 0.76 and 0.80, respectively). Moreover, the BPSD13Q was positively correlated with the NPI-NH (<i>r</i> = 0.72, <i>p</i> < 0.001) and BPSD + Q (<i>r</i> = 0.95, <i>p</i> < 0.001). The BPSD13Q-D was positively correlated with the NPI-NH-caregiver distress (<i>r</i> = 0.74, <i>p</i> < 0.001) and BPSD + Q-distress (<i>r</i> = 0.96, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>We developed and validated the BPSD13Q, which is a short-form version of the BPSD + Q and is downloadable. The BPSD13Q may make BPSD evaluations easier for the care staff.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"222-226"},"PeriodicalIF":2.3,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/2d/dee-0011-0222.PMC8543349.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Dementia and Associated Factors among Older Adults in Latin America during the COVID-19 Pandemic.","authors":"Marcio Soto-Añari, Loida Camargo, Miguel Ramos-Henderson, Claudia Rivera-Fernández, Lucia Denegri-Solís, Ursula Calle, Nicanor Mori, Ninoska Ocampo-Barbá, Fernanda López, Maria Porto, Nicole Caldichoury-Obando, Carol Saldías, Pascual Gargiulo, Cesar Castellanos, Salomon Shelach-Bellido, Norman López","doi":"10.1159/000518922","DOIUrl":"10.1159/000518922","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has had a great impact on cognitive health in Latin American older adults, increasing the risk of cognitive impairment and dementia. Our objective was to analyze the prevalence of dementia and the associated factors in Latin American older adults during SARS-CoV-2 pandemic.</p><p><strong>Methods: </strong>A multicentric first phase cross-sectional observational study was conducted during the SARS-CoV-2 pandemic. Five thousand two hundred and forty-five Latin American adults over 60 years of age were studied in 10 countries: Argentina, Bolivia, Chile, Colombia, Ecuador, Guatemala, Mexico, Peru, the Dominican Republic, and Venezuela. We used the telephone version of Montreal Cognitive Assessment, the \"Alzheimer Disease 8\" scale for functional and cognitive changes, and the abbreviated version of the Yesavage depression scale. We also asked for sociodemographic and lockdown data. All the evaluation was made by telephone. Cross-tabulations and χ² tests were used to determine the variability of the prevalence of impairment by sociodemographic characteristics and binary logistic regression to assess the association between dementia and sociodemographic factors.</p><p><strong>Results: </strong>We observed that the prevalence of dementia in Latin America is 15.6%, varying depending on the country (Argentine = 7.83 and Bolivia = 28.5%). The variables most associated with dementia were race and age. It does not seem to be associated with the pandemic but with social and socio-health factors.</p><p><strong>Conclusion: </strong>The prevalence of dementia shows a significant increase in Latin America, attributable to a constellation of ethnic, demographic, and socioeconomic factors.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"11 3","pages":"213-221"},"PeriodicalIF":2.3,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/87/dee-0011-0213.PMC8543347.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}