Pediatric Infection and Vaccine最新文献_第7页

Epidemiology of Staphylococcus aureus Bacteremia in Children at a Single Center from 2002 to 2016 2002 - 2016年某中心儿童金黄色葡萄球菌菌血症流行病学分析

Pediatric Infection and Vaccine Pub Date : 2019-04-01 DOI: 10.14776/PIV.2019.26.E2

Seonhee Lim, Seok Gyun Ha, H. Tchah, I. Jeon, E. Ryoo, D. Son, Hye Jung Cho, Yonghan Sun, Hyo Jung Kim, J. Ahn, H. Cho

{"title":"Epidemiology of Staphylococcus aureus Bacteremia in Children at a Single Center from 2002 to 2016","authors":"Seonhee Lim, Seok Gyun Ha, H. Tchah, I. Jeon, E. Ryoo, D. Son, Hye Jung Cho, Yonghan Sun, Hyo Jung Kim, J. Ahn, H. Cho","doi":"10.14776/PIV.2019.26.E2","DOIUrl":"https://doi.org/10.14776/PIV.2019.26.E2","url":null,"abstract":"목적: 본 연구를 통해 소아청소년에서 발생한 황색 포도알균혈증(Staphylococcus aureus bacteremia; SAB)의 역학적 특성을 알아보고자 하였다.\u0000방법: 2002년부터 2016년까지 15년 간 가천대 길병원에 입원한 18세 이하 소아청소년 중 SAB 환자의 의무기록을 후향적으로 분석하였다.\u0000결과: 총 212명의 소아청소년 SAB 환자가 분석에 포함되었다. 2002년부터 2016년까지 연간 SAB 발생률은 입원환자 1,000명당 0.77-1.95명이었다. 전체 SAB 중 신생아군(28일 미만)과 소아청소년군(28일-18세 이하)은 각각 51.4% (n=109), 48.6% (n=103)이었으며, 지역사회 관련 감염(community associated [CA])과 의료기관 관련 감염(healthcare associated [HA])은 각각 43.9% (n=93), 56.1% (n=119)였다. 소아청소년군(47.6%)보다 신생아군(64.2%)에서 HA-SAB의 비중이 더 높았다(P=0.015). CA-SAB와 HA-SAB에서 합병증 발생 여부는 차이가 없었으나, 사망률은 HA-SAB에서 더 높았다. 메티실린 내성 황색포도알균(methicillin-resistance S. aureus [MRSA])의 비율은 신생아군에서 가장 높았고(88.1%), 연령이 증가할수록 감소하여 5세 이상에서는 36.4-37.5%였다. MRSA 비율은 72.2%로 시간에 따른 일정한 추세는 보이지 않았다.\u0000결론: 지난 15년 간 소아청소년에서 SAB의 발생률 및 MRSA의 비율은 일정한 추세 없이 유지되었다. 소아청소년의 SAB에서 적절한 항생제를 선택하기 위해 환자의 연령 및 감염 기원에 대한 신중한 고려가 필요하다.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42858714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Clinical Features of Staphylococcal Scalded Skin Syndrome Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus in Changwon City, Korea, during 2006 and 2015 2006年至2015年韩国昌原市社区相关耐甲氧西林金黄色葡萄球菌引起的葡萄球菌烫伤皮肤综合征的临床特征

Pediatric Infection and Vaccine Pub Date : 2019-04-01 DOI: 10.14776/PIV.2019.26.E5

Jun Hyeong Park, Min Chae Kim, J. Kang, Jae Won Choi, Hak-Sung Lee, J. Shin, Je Chul Lee, S. Ma

{"title":"Clinical Features of Staphylococcal Scalded Skin Syndrome Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus in Changwon City, Korea, during 2006 and 2015","authors":"Jun Hyeong Park, Min Chae Kim, J. Kang, Jae Won Choi, Hak-Sung Lee, J. Shin, Je Chul Lee, S. Ma","doi":"10.14776/PIV.2019.26.E5","DOIUrl":"https://doi.org/10.14776/PIV.2019.26.E5","url":null,"abstract":"Purpose: We investigated the clinical features and epidemiology of staphylococcal scalded skin syndrome (SSSS) from year 2006 to 2015 in Changwon city, Korea. Methods: We reviewed medical records of 69 patients diagnosed with SSSS from year 2006 to 2015. Antibiotic susceptibility testing was performed by agar dilution method. Methicillinresistant Staphylococcus aureus (MRSA) was phenotypically identified by oxacillin susceptibility testing and genotypically confirmed by the existence of the mecA gene. Results: The median age of patients was 2.0 years (range 0.2–6 years). Three (4.3%), 53 (76.8%), and 13 (18.9%) patients showed the generalized type, the intermediate type, and the abortive type, respectively. Patients occurred throughout the year, but most patients occurred between July and October. MRSA was isolated from 54 of the 60 patients regardless of the clinical types. All patients recovered without any complications. Pediatr Infect Vaccine. 2019 Apr;26(1):42-50 https://doi.org/10.14776/piv.2019.26.e5 pISSN 2384-1079·eISSN 2384-1087","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49488036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Case Report of Newborn Prenatally infected by Human Immunodeficiency Virus in Republic of Korea 韩国新生儿产前感染人类免疫缺陷病毒1例报告

Pediatric Infection and Vaccine Pub Date : 2019-04-01 DOI: 10.14776/PIV.2019.26.E8

Kyoung Eun Lee, Won Young Lee, Eui Kyung Choi, Jeonghee Shin, B. Choi, Y. Kim

引用次数: 1

Brachial Artery Thrombosis in an 8-year-old Boy with Antiphospholipid Antibodies Induced by Mycoplasma pneumoniae Infection: a Case Report 肺炎支原体感染致抗磷脂抗体8岁男童臂动脉血栓1例

Pediatric Infection and Vaccine Pub Date : 2019-04-01 DOI: 10.14776/PIV.2019.26.E7

Junghee Woo, J. Kwon, Bo-Kyung Je, Jae Seoung Shin, W. H. Seo, G. Jang

引用次数: 2

Clinical Manifestations of PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis) Syndrome from a Single Center 来自单一中心的PFAPA(周期性发热、口疮性口炎、咽炎和腺炎)综合征的临床表现

Pediatric Infection and Vaccine Pub Date : 2019-01-01 DOI: 10.14776/piv.2019.26.e20

M. Shin, E. Choi, M. Han

{"title":"Clinical Manifestations of PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis) Syndrome from a Single Center","authors":"M. Shin, E. Choi, M. Han","doi":"10.14776/piv.2019.26.e20","DOIUrl":"https://doi.org/10.14776/piv.2019.26.e20","url":null,"abstract":"Purpose: Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is a leading cause of periodic fever in children. This study describes the clinical characteristics of PFAPA syndrome in patients from a single center. Methods: Thirteen children diagnosed with PFAPA syndrome at Seoul National University Children's Hospital were included in this study. Retrospective medical chart reviews were performed. Results: Among the 13 patients, 8 (61.5%) were male. The median follow-up duration was 3.3 years (range, 10 months–8.3 years). The median age of periodic fever onset was 3 years (range, 1–6 years). All patients had at least 5 episodes of periodic fever and pharyngitis, managed with oral antibiotics, before diagnosis. The median occurrence of fever was every 3.9 weeks and lasted for 4.2 days. All patients had pharyngitis and 12 (92.3%) had cervical lymphadenitis. Blood tests were performed for 12 patients, and no patients had neutropenia. Both the C-reactive protein and erythrocyte sedimentation rate were elevated at medians of 4.5 mg/ dL (range, 0.4–13.2 mg/dL) and 29 mm/hr (range, 16–49 mm/hr), respectively. Throat swab cultures and rapid streptococcal antigen tests were negative. Nine (69.2%) patients received oral prednisolone at a median dose of 0.8 mg/kg, and in 6 (66.7%) patients, fever resolved within a few hours. Three (23.1%) patients received tonsillectomy and adenoidectomy. Conclusions: PFAPA syndrome should be considered when a child presents with periodic fever along with aphthous stomatitis, pharyngitis, or cervical lymphadenitis. Glucocorticoid administration is effective for fever resolution and can reduce unnecessary use of antibiotics.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66641482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory Microbiome in Children 儿童呼吸道微生物组

Pediatric Infection and Vaccine Pub Date : 2019-01-01 DOI: 10.14776/piv.2019.26.e24

Dong Hyun Kim

引用次数: 0

Childhood Tuberculosis Contact Investigation and Treatment of Latent Tuberculosis Infection: a Single Center Study, 2014–2017 2014-2017年儿童结核接触者调查与潜伏性结核感染治疗:单中心研究

Pediatric Infection and Vaccine Pub Date : 2019-01-01 DOI: 10.14776/piv.2019.26.e4

W. Hwang, G. Lee, So Hyun Kim, Eun Young Cho

引用次数: 3

Neonatal Sepsis and Meningitis Caused by Neisseria meningitidis Serogroup B: a Case Report 乙型脑膜炎奈瑟菌引起的新生儿败血症和脑膜炎1例报告

Pediatric Infection and Vaccine Pub Date : 2018-12-01 DOI: 10.14776/PIV.2018.25.E13

Yoo Na Kim, Yong Sung Choi, S. Cha

引用次数: 2

Epidemiology and Clinical Characteristics of Parainfluenza Virus Type 4 in Korean Children: a Single Center Study, 2015–2017 2015-2017年韩国儿童4型副流感病毒流行病学及临床特征的单中心研究

Pediatric Infection and Vaccine Pub Date : 2018-12-01 DOI: 10.14776/PIV.2018.25.E12

Young Joo Sohn, Y. Choi, K. Yun, E. Choi, H. Lee

{"title":"Epidemiology and Clinical Characteristics of Parainfluenza Virus Type 4 in Korean Children: a Single Center Study, 2015–2017","authors":"Young Joo Sohn, Y. Choi, K. Yun, E. Choi, H. Lee","doi":"10.14776/PIV.2018.25.E12","DOIUrl":"https://doi.org/10.14776/PIV.2018.25.E12","url":null,"abstract":"Purpose: We aimed to identify the epidemiology and the clinical characteristics of human parainfluenza virus type 4 (HPIV-4) infection compared to HPIVs 1–3 infections in Korean children. Methods: We reviewed medical records of children with HPIV infection who visited Seoul National University Children's Hospital from 2015 to 2017. Detection of respiratory viruses was performed using real time-polymerase chain reaction (rt-PCR), which could differentiate HPIVs 1–4. Diagnosis was classified as a febrile illness, upper respiratory tract infection (URI), croup, bronchiolitis, or pneumonia. The epidemiology, demographic features, and clinical characteristics among HPIV types were compared. The clinical data were analyzed only for the previously healthy children. Results: Of the 472 children diagnosed with HPIV infection, 108 (22.9%) were previously healthy: 24 (22.2%), 19 (17.6%), 39 (36.1%), and 26 (24.1%) in HPIV types 1, 2, 3, and 4, respectively. The median age of children with HPIV-4 infection was 11 (0–195) months: the proportion of children aged < 2 years and 2 to < 5 years were 65.4% and 19.2%, respectively. Clinical diagnoses of HPIV-4 infection were bronchiolitis (38.5%), pneumonia (30.8%), and URI (30.8%). Croup was the most prevalent in HPIV-2 (21.1%) and none in HPIV-4 infection (P=0.026). Hospital admission rates among HPIV types were not significantly different (P>0.05). Conclusions: We observed seasonal peak of HPIV-4 infection in 2015 and 2017. HPIV-4 was a common respiratory pathogen causing lower respiratory tract infection in hospitalized children.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77449743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

임신 중 Tdap 접종에 대한 임부들의 인식, 태도 및 행동 孕妇对孕期Tdap接种的认识、态度及行为

Pediatric Infection and Vaccine Pub Date : 2018-12-01 DOI: 10.14776/PIV.2018.25.E10

이 신혜, 진 보경, 백 경숙, 조 용선, 이 택진

{"title":"임신 중 Tdap 접종에 대한 임부들의 인식, 태도 및 행동","authors":"이 신혜, 진 보경, 백 경숙, 조 용선, 이 택진","doi":"10.14776/PIV.2018.25.E10","DOIUrl":"https://doi.org/10.14776/PIV.2018.25.E10","url":null,"abstract":"목적: 임신 중 tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) 접종의 효과 및 안전성에도 불구하고, 아직 국내 임신 중 Tdap 접종률은 낮다. 이에 저자들은 임신 중 Tdap 접종에 대한 임부들의 인식, 태도 및 행동에 대한 조사를 하였다.\u0000방법: 본 연구는 서울 및 경기 소재 대학병원 산부인과를 방문한 임부를 대상으로 개별적인 설문지를 통해 임신 중 Tdap 접종에 대한 인식, 태도 및 행동을 수집한 단면 설문조사다.\u0000결과: 총 184명의 임부들이 설문지 작성을 완료하였다. 이 중 158명(86%)의 임부들은 의사로부터 백일해 및 Tdap 백신에 대한 정보를 안내 받지 못했고, 166명(90%)의 임부들은 임신 중 Tdap 접종의 필요성을 알지 못했다. 현 임신기간 중 Tdap 접종을 하지 않을 것이라고 답한 임부 중 7%만이 백일해 및 백신에 대한 이해를 묻는 5문항 중 3문항 이상 올바르게 답하였다. 로지스틱 회귀분석에서 의사의 추천(adjusted odds ratio [OR], 236.2; 95% confidence interval [CI], 12.6-4,432), 백신이 효과적이라는 믿음(adjusted OR, 40.21; 95% CI, 2.35-687.7), 백신이 안전하다는 믿음(adjusted OR, 19.83; 95% CI, 1.54-255.9) 등이 Tdap 접종을 결정하는데 유의하게 중요한 요인이었다.\u0000결론: 대부분의 임부들이 Tdap 접종에 대하여 적절하게 안내를 받지 못하거나, 추천받지 못하는 것으로 보인다. 임부들의 Tdap 접종률을 향상시키는 데에 의료기관 종사자에 의해 제공되는 정보가 매우 중요하다.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91000903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0