Pediatric Infection and Vaccine最新文献

A Rare Case of Brain Abscess Caused by Aggregatibacter aphrophilus and Actinomyces georgiae in an Immunocompetent Child 免疫功能正常儿童嗜aphrophilus聚集菌及放线菌所致脑脓肿一例

Pediatric Infection and Vaccine Pub Date : 2023-01-01 DOI: 10.14776/piv.2023.30.e16

Soojeong Bae, Su Jin Lee, Ye Kyung Kim, Hee-Won Moon, Kyung Rae Cho, Ran Lee

引用次数: 0

Severe Human Rhinovirus Lower Respiratory Tract Infections in Young Children 幼儿严重人鼻病毒下呼吸道感染

Pediatric Infection and Vaccine Pub Date : 2023-01-01 DOI: 10.14776/piv.2023.30.e17

Doo Ri Kim, Kyung-Ran Kim, Hwanhee Park, Esther Park, Joongbum Cho, Jihyun Kim, Hee Jae Huh, Kangmo Ahn, Nam Yong Lee, Yae-Jean Kim

引用次数: 0

Acute Appendicitis: A Rare But Probable Manifestation of Kawasaki Disease 急性阑尾炎:川崎病罕见但可能的表现

Pediatric Infection and Vaccine Pub Date : 2023-01-01 DOI: 10.14776/piv.2023.30.e9

Wonshik Choi, Sin Weon Yun, Mineui Hong, Suk-Won Suh, Dae Yong Yi, Ji Young Park

引用次数: 0

CD45RA+ Depleted Lymphocyte Infusion for Treatment of Refractory Cytomegalovirus Disease in Complete DiGeorge Syndrome: A Case Report CD45RA+贫淋巴细胞输注治疗难治性巨细胞病毒病完全性迪乔治综合征1例

Pediatric Infection and Vaccine Pub Date : 2023-01-01 DOI: 10.14776/piv.2023.30.e18

HyungJin Chin, Young Hye Ryu, Da Yun Kang, Hyun Jin Park, Kyung Taek Hong, Jung Yoon Choi, Ki Wook Yun, Bongjin Lee, Hyoung Jin Kang, Eun Hwa Choi

引用次数: 0

Acute Hemorrhagic Edema of Infancy Associated With Coronavirus Disease 2019 与2019冠状病毒病相关的婴儿急性出血性水肿

Pediatric Infection and Vaccine Pub Date : 2023-01-01 DOI: 10.14776/piv.2023.30.e14

Jong Ki Jung, Young June Choe, Hwa Jung Ryu, Won-Hee Seo

引用次数: 0

Clinical and Epidemiological Characteristics of Common Human Coronaviruses in Children: A Single Center Study, 2015–2019 儿童常见人类冠状病毒的临床和流行病学特征：一项单中心研究，2015-2019

Pediatric Infection and Vaccine Pub Date : 2021-08-01 DOI: 10.14776/piv.2021.28.e10

Y. Choi, Y. Kim, E. Choi

{"title":"Clinical and Epidemiological Characteristics of Common Human Coronaviruses in Children: A Single Center Study, 2015–2019","authors":"Y. Choi, Y. Kim, E. Choi","doi":"10.14776/piv.2021.28.e10","DOIUrl":"https://doi.org/10.14776/piv.2021.28.e10","url":null,"abstract":"Purpose: Common human coronaviruses (HCoVs) are relatively understudied due to the mild nature of HCoV infection. Given the lack of local epidemiology data on common HCoVs, we aimed to describe clinical and epidemiological characteristics of common HCoVs in children. Methods: Respiratory viral test results from 9,589 respiratory samples from Seoul National University Children's Hospital were analyzed from January 2015 to December 2019. Viral detection was done by the multiplex reverse transcription polymerase chain reaction. Demographics and clinical diagnosis were collected for previously healthy children tested positive for HCoVs. Results: Of the 9,589 samples tested, 1 or more respiratory viruses were detected from 5,017 (52.3%) samples and 463 (4.8%) samples were positive for HCoVs (OC43 2.8%, NL63 1.4%, 229E 0.7%). All 3 types co-circulated during winter months (November to February) with some variation by type. HCoV-OC43 was the most prevalent every winter season. HCoV-NL63 showed alternate peaks in late winter (January to March) and early winter (November to February). HCoV-229E had smaller peaks every other winter. Forty-one percent of HCoV-positive samples were co-detected with additional viruses;human rhinovirus 13.2%, respiratory syncytial virus 13.0%, influenza virus 4.3%. Common clinical diagnosis was upper respiratory tract infection (60.0%) followed by pneumonia (14.8%), croup (8.1%), and bronchiolitis (6.7%). Croup accounted for 17.0% of HCoV-NL63-positive children. Conclusions: This study described clinical and epidemiological characteristics of common HCoVs (OC43, NL63, 229E) in children. Continuing surveillance, perhaps by adding HKU1 in the diagnostic panel can further elucidate the spectrum of common HCoV infections in children. © 2021 The Korean Society of Pediatric Infectious Diseases.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44772617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

BioFire® Meningitis/Encephalitis Panel의 진단적 유용성 평가: 90일 미만 발열 영아에서의 예비 연구 BioFire®Meningitis/Encephalitis Panel的诊断有用性评价:对发热90天婴儿的初步研究

Pediatric Infection and Vaccine Pub Date : 2021-08-01 DOI: 10.14776/PIV.2021.28.E9

김 경민, 박 지영, 박 경운, 손 영주, 최 윤영, 한 미선, 최 은화

引用次数: 1

Multisystem Inflammatory Syndrome in Children (MIS-C) 儿童多系统炎症综合征（MIS-C）

Pediatric Infection and Vaccine Pub Date : 2021-08-01 DOI: 10.14776/piv.2021.28.e13

J. Lee, E. Cho, Hyunju Lee

{"title":"Multisystem Inflammatory Syndrome in Children (MIS-C)","authors":"J. Lee, E. Cho, Hyunju Lee","doi":"10.14776/piv.2021.28.e13","DOIUrl":"https://doi.org/10.14776/piv.2021.28.e13","url":null,"abstract":"The coronavirus disease 2019 pandemic has been continuously spreading throughout the world. As of July 15, 2021, there have been more than 188 million confirmed cases and more than 4.06 million deaths. Although the incidence of severe infections is relatively low in children and adolescents compared to adults, a complication called multisystem inflammatory syndrome in children (MIS-C) may occur in some cases at approximately 2–6 weeks after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. MIS-C can be seen in patients of various ages, from young infants to adolescents, and may present with diverse clinical manifestations. While fever present in a great majority of patients, symptoms suggesting the involvement of the digestive or nervous system and the skin and mucous membranes (Kawasaki disease-like symptoms) also appear in many cases. Cardiac involvement may also be observed, including left ventricular dysfunction, myocarditis, coronary artery dilatation, and coronary aneurysm. In some cases, hypotension or shock can occur, and mechanical ventilation or treatment in the intensive care unit may be necessary. Fortunately, recovery is generally reported after appropriate treatment. MIS-C is a rare but important complication of SARS-CoV-2 infection in children and adolescents. As such, it is important to recognize the clinical symptoms and provide appropriate treatment at an early stage. In this review, the epidemiology, clinical symptoms, suggested pathophysiology, diagnostic approach, and treatment of MIS-C will be discussed. © 2021 The Korean Society of Pediatric Infectious Diseases.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42257543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Cryptococcosis with Mediastinal Lymph Node and Lung Involvement in an Immunocompetent Adolescent: A Case Report 免疫功能正常青少年隐球菌病伴纵隔淋巴结和肺部受累一例报告

Pediatric Infection and Vaccine Pub Date : 2021-08-01 DOI: 10.14776/piv.2021.28.e7

Jiyeon Lee, C. Cho, Hyun Cho, H. Park, Kyung-Hyo Kim

引用次数: 0

Evaluation of Interferon-gamma Release Assay in Children with Confirmed Tuberculosis 儿童结核确诊患者干扰素释放试验的评价

Pediatric Infection and Vaccine Pub Date : 2021-04-01 DOI: 10.14776/PIV.2021.28.E5

Kyu Ho Kim, Ji‐Man Kang, Jong Gyun Ahn

{"title":"Evaluation of Interferon-gamma Release Assay in Children with Confirmed Tuberculosis","authors":"Kyu Ho Kim, Ji‐Man Kang, Jong Gyun Ahn","doi":"10.14776/PIV.2021.28.E5","DOIUrl":"https://doi.org/10.14776/PIV.2021.28.E5","url":null,"abstract":"Purpose: This study aimed to evaluate the diagnostic value of the QuantiFERON-TB Gold InTube (QFT-GIT) in children with confirmed tuberculosis (TB). Methods: We retrospectively reviewed the medical records of children aged ≤18 years who underwent both QFT-GIT and Mycobacterium tuberculosis culture between 2006 and 2017. Confirmed TB was defined as the presence of at least one positive specimen for M. tuberculosis on culture or a nucleic acid amplification test. Results: Of the 582 patients included in the analysis, 48 were confirmed to have TB. The sensitivity and specificity of QFT-GIT for the diagnosis of confirmed TB were 85.4% and 95.5%, respectively. Among children with confirmed TB, the proportion in the immunocompromised state was higher in the QFT-GIT negative group than in the QFT-GIT positive group (50.0% vs. 5.7%, P=0.010). The median age at sampling was lower in the QFTGIT indeterminate group than in the QFT-GIT positive group (7 years vs. 17 years, P=0.008), and the proportion of immunosuppression was higher in the QFT-GIT indeterminate group than in the QFT-GIT positive group (42.9% vs. 5.7%, P=0.017). The interferon gamma response to mitogen control was significantly higher in the 10–18 years group than in the 0–9 years group (P<0.001), and was significantly higher in the immunocompetent group than in the immunocompromised group (P=0.001). Conclusion: The QFT-GIT results should be interpreted carefully in immunocompromised or younger children suspected of having TB.","PeriodicalId":37997,"journal":{"name":"Pediatric Infection and Vaccine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46315185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0