Neurobiology of Sleep and Circadian Rhythms最新文献_第6页

Phenotypic plasticity of circadian entrainment under a range of light conditions 一系列光照条件下昼夜节律夹带的表型可塑性

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-11-01 DOI: 10.1016/j.nbscr.2020.100055

C.R.C. Moreno , K. Wright Jr. , D.J. Skene , F.M. Louzada

引用次数: 8

Sleep and circadian rhythms: Evolutionary entanglement and local regulation 睡眠和昼夜节律:进化纠葛和局部调控

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-11-01 DOI: 10.1016/j.nbscr.2020.100052

James M. Krueger

引用次数: 8

The interaction of the circadian and immune system: Desynchrony as a pathological outcome to traumatic brain injury 昼夜节律和免疫系统的相互作用:非同步作为创伤性脑损伤的病理结果

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-11-01 DOI: 10.1016/j.nbscr.2020.100058

G.R. Yamakawa , R.D. Brady , M. Sun , S.J. McDonald , S.R. Shultz , R. Mychasiuk

{"title":"The interaction of the circadian and immune system: Desynchrony as a pathological outcome to traumatic brain injury","authors":"G.R. Yamakawa , R.D. Brady , M. Sun , S.J. McDonald , S.R. Shultz , R. Mychasiuk","doi":"10.1016/j.nbscr.2020.100058","DOIUrl":"10.1016/j.nbscr.2020.100058","url":null,"abstract":"<div><p>Traumatic brain injury (TBI) is a complex and costly worldwide phenomenon that can lead to many negative health outcomes including disrupted circadian function. There is a bidirectional relationship between the immune system and the circadian system, with mammalian coordination of physiological activities being controlled by the primary circadian pacemaker in the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN receives light information from the external environment and in turn synchronizes rhythms throughout the brain and body. The SCN is capable of endogenous self-sustained oscillatory activity through an intricate clock gene negative feedback loop. Following TBI, the response of the immune system can become prolonged and pathophysiological. This detrimental response not only occurs in the brain, but also within the periphery, where a leaky blood brain barrier can permit further infiltration of immune and inflammatory factors. The prolonged and pathological immune response that follows TBI can have deleterious effects on clock gene cycling and circadian function not only in the SCN, but also in other rhythmic areas throughout the body. This could bring about a state of circadian desynchrony where different rhythmic structures are no longer working together to promote optimal physiological function. There are many parallels between the negative symptomology associated with circadian desynchrony and TBI. This review discusses the significant contributions of an immune-disrupted circadian system on the negative symptomology following TBI. The implications of TBI symptomology as a disorder of circadian desynchrony are discussed.</p></div>","PeriodicalId":37827,"journal":{"name":"Neurobiology of Sleep and Circadian Rhythms","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.nbscr.2020.100058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38751962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Juvenile hormone affects the development and strength of circadian rhythms in young bumble bee (Bombus terrestris) workers 幼崽激素影响小黄蜂(Bombus terrestris)工蜂昼夜节律的发育和强度

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-05-25 DOI: 10.1101/2020.05.24.101915

A. Pandey, U. Motro, G. Bloch

{"title":"Juvenile hormone affects the development and strength of circadian rhythms in young bumble bee (Bombus terrestris) workers","authors":"A. Pandey, U. Motro, G. Bloch","doi":"10.1101/2020.05.24.101915","DOIUrl":"https://doi.org/10.1101/2020.05.24.101915","url":null,"abstract":"The circadian and endocrine systems influence many physiological processes in animals, but little is known on the ways they interact in insects. We tested the hypothesis that juvenile hormone (JH) influences circadian rhythms in the social bumble bee Bombus terrestris. JH is the major gonadotropin in this species coordinating processes such as vitellogenesis, oogenesis, wax production, and behaviors associated with reproduction. It is unknown however, whether it also influences circadian processes. We topically treated newly-emerged bees with the allatoxin Precocene-I (P-I) to reduce circulating JH titers and applied the natural JH (JH-III) for replacement therapy. We repeated this experiment in three trials, each with bees from different source colonies. Measurements of ovarian activity confirmed that our JH manipulations were effective; bees treated with P-I had inactive ovaries, and this effect was fully reverted by subsequent JH treatment. We found that JH augments the strength of circadian rhythms and the pace of rhythm development in individually isolated newly emerged worker bees. JH manipulation did not affect the free-running circadian period, overall level of locomotor activity, or the amount of sleep. Given that acute manipulation at an early age produced relatively long-lasting effects, we propose that JH effect on circadian rhythms is mostly organizational, accelerating the development or integration of the circadian system.","PeriodicalId":37827,"journal":{"name":"Neurobiology of Sleep and Circadian Rhythms","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47889545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Suprachiasmatic lesions restore object recognition in down syndrome model mice 视交叉上损伤恢复唐氏综合症模型小鼠的物体识别能力

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-05-01 DOI: 10.1016/j.nbscr.2020.100049

Bayarsaikhan Chuluun , Elsa Pittaras , Hyunseung Hong, Nathan Fisher, Damien Colas, Norman F. Ruby, H. Craig Heller

{"title":"Suprachiasmatic lesions restore object recognition in down syndrome model mice","authors":"Bayarsaikhan Chuluun , Elsa Pittaras , Hyunseung Hong, Nathan Fisher, Damien Colas, Norman F. Ruby, H. Craig Heller","doi":"10.1016/j.nbscr.2020.100049","DOIUrl":"10.1016/j.nbscr.2020.100049","url":null,"abstract":"<div><p>The Ts65Dn mouse is a well-studied model of trisomy 21, Down syndrome. This mouse strain has severe learning disability as measured by several rodent learning tests that depend on hippocampal spatial memory function. Hippocampal long-term potentiation (LTP) is deficient in these mice. Short-term daily treatment with low-dose GABA receptor antagonists rescue spatial learning and LTP in Ts65Dn mice leading to the hypothesis that the learning disability is due to GABAergic over-inhibition of hippocampal circuits. The fact that the GABA receptor antagonists were only effective if delivered during the daily light phase suggested that the source of the excess GABA was controlled directly or indirectly by the circadian system. The central circadian pacemaker of mammals is the suprachiasmatic nucleus (SCN), which is largely a GABAergic nucleus. In this study we investigated whether elimination of the SCN in Ts65Dn mice would restore their ability to form recognition memories as tested by the novel object recognition (NOR) task. Full, but not partial lesions of the SCN of Ts65Dn mice normalized their ability to perform on the NOR test. These results suggest that the circadian system modulates neuroplasticity over the time frame involved in the process of consolidation of recognition memories.</p></div>","PeriodicalId":37827,"journal":{"name":"Neurobiology of Sleep and Circadian Rhythms","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.nbscr.2020.100049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37757344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Surveying sleep quality and fatigue in multiple sclerosis patients at a multiple sclerosis center in Kermanshah, Iran, in 2017 2017年，在伊朗克尔曼沙阿的一个多发性硬化症中心调查了多发性硬化症患者的睡眠质量和疲劳

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-05-01 DOI: 10.1016/j.nbscr.2020.100050

Saba Karimi , Milad Jalilian , Alireza Abdi , Habibolah Khazaie , Pegah Ahmadi Sarbarzeh

{"title":"Surveying sleep quality and fatigue in multiple sclerosis patients at a multiple sclerosis center in Kermanshah, Iran, in 2017","authors":"Saba Karimi , Milad Jalilian , Alireza Abdi , Habibolah Khazaie , Pegah Ahmadi Sarbarzeh","doi":"10.1016/j.nbscr.2020.100050","DOIUrl":"10.1016/j.nbscr.2020.100050","url":null,"abstract":"<div><h3>Background</h3><p>Multiple sclerosis (MS) is an autoimmune disease of the nervous system which appears with de-myelination of the central nervous system. Sleep disorder and fatigue are very common in MS patients and are part of the main debilitating factors in patients. The present study was conducted to survey sleep quality and fatigue in MS patients.</p></div><div><h3>Methods</h3><p>A descriptive-analytical study was conducted on 87 MS patients, who were referred to the Kermanshah MS Center in 2017. Data collection tools include a demographics form, fatigue severity scale, and Pittsburg sleep quality inventory. The questionnaires were self-reporting. The collected data was analyzed in SPSS23.</p></div><div><h3>Results</h3><p>The mean age of the participants was 35.50±9.25 years and the majority of the participants were married (54; 62.1%). Quality of sleep was related to family history of MS and history of using medications (antidepressants like tricyclics, MAOIs, SSRIs, and SNRIs and anxiety drugs such as diazepam, oxazepam, and alprazolam (p < 0.05). Moreover, there was a significant relationship between length of sleep and history of using medicines (p < 0.05). Finally, the results showed that there was a strong statistical relationship between performance during the day and fatigue (p < 0.05).</p></div><div><h3>Conclusions</h3><p>The results recommend holding relaxation and exercise courses by nurses to ease fatigue in MS patients. Clinics can also play a more effective role by being more supportive and holding more efficient training programs. The program is taught by the researchers.</p></div><div><h3>Trial registration</h3><p>This study was carried out following the permission from Ethics Committee, Department of Research and Technology, Kermanshah University of Medical Sciences (approval number: KUMS.REC.1395.680).</p></div>","PeriodicalId":37827,"journal":{"name":"Neurobiology of Sleep and Circadian Rhythms","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.nbscr.2020.100050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37974918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Delayed Sleep-Wake Phase Disorder 延迟睡眠-觉醒阶段障碍

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-43803-6_6

Gregory S. Carter, R. Robert Auger

引用次数: 1

Shift Work Sleep Disorder 轮班工作睡眠障碍

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-43803-6_11

Alok Sachdeva, Cathy A Goldstein

引用次数: 1

Irregular Sleep-Wake Rhythm Disorder 不规则睡眠-觉醒节律障碍

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-43803-6_10

Danielle Goldfarb, K. Sharkey

引用次数: 1

Non-physiologic Methods of Assessment Relevant to Circadian Rhythm Sleep-Wake Disorders 与昼夜节律睡眠-觉醒障碍相关的非生理性评估方法

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-43803-6_5

Vincent A. LaBarbera, K. Sharkey

引用次数: 1