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Extracorporeal Life Support for Cardiac Arrest and Cardiogenic Shock 心脏骤停和心源性休克的体外生命支持
US Cardiology Review Pub Date : 2021-11-10 DOI: 10.15420/usc.2021.13
Andrea Elliott, Garima Dahyia, R. Kalra, T. Alexy, J. Bartos, M. Kosmopoulos, D. Yannopoulos
{"title":"Extracorporeal Life Support for Cardiac Arrest and Cardiogenic Shock","authors":"Andrea Elliott, Garima Dahyia, R. Kalra, T. Alexy, J. Bartos, M. Kosmopoulos, D. Yannopoulos","doi":"10.15420/usc.2021.13","DOIUrl":"https://doi.org/10.15420/usc.2021.13","url":null,"abstract":"The rising incidence and recognition of cardiogenic shock has led to an increase in the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO). As clinical experience with this therapy has increased, there has also been a rapid growth in the body of observational and randomized data describing the clinical and logistical considerations required to institute a VA-ECMO program with successful clinical outcomes. The aim of this review is to summarize this contemporary data in the context of four key themes that pertain to VA-ECMO programs: the principles of patient selection; basic hemodynamic and technical principles underlying VA-ECMO; contraindications to VA-ECMO therapy; and common complications and intensive care considerations that are encountered in the setting of VA-ECMO therapy.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43324504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Current Landscape of Temporary Percutaneous Mechanical Circulatory Support Technology 临时经皮机械循环支持技术的现状
US Cardiology Review Pub Date : 2021-11-02 DOI: 10.15420/usc.2021.15
Rani Upadhyay, Hussayn Alrayes, Scott Arno, M. Kaushik, M. Basir
{"title":"Current Landscape of Temporary Percutaneous Mechanical Circulatory Support Technology","authors":"Rani Upadhyay, Hussayn Alrayes, Scott Arno, M. Kaushik, M. Basir","doi":"10.15420/usc.2021.15","DOIUrl":"https://doi.org/10.15420/usc.2021.15","url":null,"abstract":"Mechanical circulatory support devices provide hemodynamic support to patients who present with cardiogenic shock. These devices work using different mechanisms to provide univentricular or biventricular support. There is a growing body of evidence supporting use of these devices as a goal for cardiac recovery or as a bridge to definitive therapy, but definitive, well-powered studies are still needed. Mechanical circulatory support devices are increasingly used using shock team and protocols, which can help clinicians in decision making, balancing operator and institutional experience and expertise. The aim of this article is to review commercially available mechanical circulatory support devices, their profiles and mechanisms of action, and the evidence available regarding their use.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47903724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Rediscovered and Unforgotten: Transcatheter Interventions for the Treatment of Severe Tricuspid Valve Regurgitation 经导管介入治疗严重三尖瓣反流
US Cardiology Review Pub Date : 2021-11-02 DOI: 10.15420/usc.2021.06
K. Rahgozar, S. Bruoha, E. Ho, Ythan H. Goldberg, M. Chau, A. Latib
{"title":"Rediscovered and Unforgotten: Transcatheter Interventions for the Treatment of Severe Tricuspid Valve Regurgitation","authors":"K. Rahgozar, S. Bruoha, E. Ho, Ythan H. Goldberg, M. Chau, A. Latib","doi":"10.15420/usc.2021.06","DOIUrl":"https://doi.org/10.15420/usc.2021.06","url":null,"abstract":"Tricuspid valve regurgitation is both globally prevalent and undertreated. Historically, surgical intervention for isolated tricuspid regurgitation (TR) was avoided despite the prevalence of TR, largely due to poor surgical outcomes and an incomplete understanding of how it independently affects mortality. Over the past two decades, TR has been shown by several studies to be an independent predictor of worse functional status and poor survival on long-term follow-up. During this same time period, transcatheter interventions for the treatment of valvular heart disease have evolved dramatically. While the transcatheter repair and replacement of the tricuspid valve in patients with severe TR remains in the early stages of investigation relative to the mitral or aortic valve, the field is rapidly expanding. Here, the authors review the field of transcatheter tricuspid valve interventions for severe TR, focusing on the orthotropic devices and valves currently available worldwide.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44076759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Cardiogenic Shock: Protocols, Teams, Centers, and Networks 心源性休克:方案、团队、中心和网络
US Cardiology Review Pub Date : 2021-10-20 DOI: 10.15420/usc.2021.10
Alex F Warren, Carolyn M. Rosner, Raghav Gattani, A. Truesdell, A. Proudfoot
{"title":"Cardiogenic Shock: Protocols, Teams, Centers, and Networks","authors":"Alex F Warren, Carolyn M. Rosner, Raghav Gattani, A. Truesdell, A. Proudfoot","doi":"10.15420/usc.2021.10","DOIUrl":"https://doi.org/10.15420/usc.2021.10","url":null,"abstract":"The mortality of cardiogenic shock (CS) remains unacceptably high. Delays in the recognition of CS and access to disease-modifying or hemodynamically stabilizing interventions likely contribute to poor outcomes. In parallel to successful initiatives in other disease states, such as acute ST-elevation MI and major trauma, institutions are increasingly advocating the use of a multidisciplinary ‘shock team’ approach to CS management. A volume–outcome relationship exists in CS, as with many other acute cardiovascular conditions, and the emergence of ‘shock hubs’ as experienced facilities with an interest in improving CS outcomes through a hub-and-spoke ‘shock network’ approach provides another opportunity to deliver improved CS care as widely and equitably as possible. This narrative review outlines improvements from a networked approach to care, discusses a team-based and protocolized approach to CS management, reviews the available evidence and discusses the potential benefits, challenges, and opportunities of such systems of care.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46027111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment 复杂经皮冠状动脉介入治疗中的抗血栓药物:治疗类型和持续时间
US Cardiology Review Pub Date : 2021-10-13 DOI: 10.15420/usc.2020.30
Despoina-Rafailia Benetou, C. Varlamos, C. Pappas, Fotios Kolokathis, D. Alexopoulos
{"title":"Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment","authors":"Despoina-Rafailia Benetou, C. Varlamos, C. Pappas, Fotios Kolokathis, D. Alexopoulos","doi":"10.15420/usc.2020.30","DOIUrl":"https://doi.org/10.15420/usc.2020.30","url":null,"abstract":"Patients undergoing complex percutaneous coronary intervention (PCI) are at an increased risk of atherothrombotic complications. Although dual antiplatelet therapy is the mainstay of treatment for patients undergoing PCI with stent implantation, deciding its type and duration in complex PCI patients has long been considered a challenge for clinicians. This is because the beneficial effects of prolonged treatment and/or more potent antiplatelet agents’ use in preventing ischemic events are hindered by a concomitant increase in bleeding complications. The aim of this review is to highlight current evidence regarding the optimal antithrombotic therapy regimens used in complex PCI patients, focusing on the evaluation of both safety and efficacy outcomes as well as addressing future perspectives.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43670731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heart Transplant and Ventricular Assist: Cardiac Surgery and Heart Failure Perspective 心脏移植与心室辅助：心脏外科与心力衰竭
US Cardiology Review Pub Date : 2021-09-24 DOI: 10.15420/usc.2021.11
M. Cain, M. Firstenberg, J. Cleveland
{"title":"Heart Transplant and Ventricular Assist: Cardiac Surgery and Heart Failure Perspective","authors":"M. Cain, M. Firstenberg, J. Cleveland","doi":"10.15420/usc.2021.11","DOIUrl":"https://doi.org/10.15420/usc.2021.11","url":null,"abstract":"For nearly 60 years, there have been two surgical treatment options for individuals with severe advanced heart failure: heart transplantation or implantation of a left ventricular assist device. As these fields have advanced in parallel, improvements in surgical technique, device development, and patient selection have improved outcomes for both therapies. Development of a comprehensive approach to the management of the most severe forms of advanced heart failure requires a deep understanding of both heart transplantation and durable ventricular assistance, including recent advancements in both fields. This article will review the substantial progress in the fields of heart transplantation and mechanical left ventricular assistance, including recent changes to organ allocation prioritization and left ventricular assist device evaluation, both of which have dramatically influenced practice in these fields.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49503696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Describing and Classifying Shock: Recent Insights 冲击的描述和分类：最近的见解
US Cardiology Review Pub Date : 2021-09-15 DOI: 10.15420/usc.2021.09
Ashleigh Long, A. Yehya, K. Stelling, D. Baran
{"title":"Describing and Classifying Shock: Recent Insights","authors":"Ashleigh Long, A. Yehya, K. Stelling, D. Baran","doi":"10.15420/usc.2021.09","DOIUrl":"https://doi.org/10.15420/usc.2021.09","url":null,"abstract":"Cardiogenic shock continues to present a daunting challenge to clinicians, despite an increasing array of percutaneous mechanical circulatory support devices. Mortality for cardiogenic shock has not changed meaningfully in more than 20 years. There have been many attempts to generate risk scores or frameworks to evaluate cardiogenic shock and optimize the use of resources and assist with prognostication. These include the Intra-Aortic Balloon Pump in Cardiogenic Shock (IABP-SHOCK) II risk score, the CardShock score and the new CLIP biomarker score. This article reviews the Society for Cardiac Angiography and Interventions (SCAI) classification of cardiogenic shock and subsequent validation studies. The SCAI classification is simple for clinicians to use as it is based on readily available information and can be adapted depending on the data set that can be accessed. The authors consider the future of the field. Underlying all these efforts is the hope that a better understanding and classification of shock will lead to meaningful improvements in mortality rates.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47941823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet Function Testing and Genotyping for Tailoring Treatment in Complex PCI Patients 血小板功能检测和基因分型对复杂PCI患者的针对性治疗
US Cardiology Review Pub Date : 2021-08-04 DOI: 10.15420/usc.2020.33
A. Moulias, A. Papageorgiou, D. Alexopoulos
{"title":"Platelet Function Testing and Genotyping for Tailoring Treatment in Complex PCI Patients","authors":"A. Moulias, A. Papageorgiou, D. Alexopoulos","doi":"10.15420/usc.2020.33","DOIUrl":"https://doi.org/10.15420/usc.2020.33","url":null,"abstract":"Dual antiplatelet therapy (DAPT), comprising aspirin and a P2Y12 receptor inhibitor, is considered the cornerstone of treatment in patients who have undergone percutaneous coronary intervention (PCI). Patients with complex PCI (C-PCI) constitute a special PCI subpopulation, characterized by increased ischemic risk. Identifying the optimal DAPT strategy is often challenging and remains controversial in this setting. In an attempt to balance ischemic and bleeding risks in C-PCI patients receiving DAPT, treatment individualization regarding potency and duration has evolved as a feasible approach. Platelet function testing and genotyping have been evaluated in several trials with conflicting and mostly neutral results. The aim of this review is to critically appreciate the role of these tools for antiplatelet treatment tailoring specifically in C-PCI patients. Because existing evidence is limited, dedicated future studies are warranted to elucidate the utility of platelet function testing and genotyping in C-PCI.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42682554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Door-to-balloon Time for ST-elevation MI in the Coronavirus Disease 2019 Era 2019冠状病毒病时代st段抬高心肌梗死的门到球囊时间
US Cardiology Review Pub Date : 2021-07-14 DOI: 10.15420/USC.2021.05
H. Mously, N. Shah, Z. Zuzek, I. Alshaghdali, Ali Mehryar Karim, R. Jaswaney, S. Filby, D. Simon, M. Shishehbor, F. Forouzandeh
{"title":"Door-to-balloon Time for ST-elevation MI in the Coronavirus Disease 2019 Era","authors":"H. Mously, N. Shah, Z. Zuzek, I. Alshaghdali, Ali Mehryar Karim, R. Jaswaney, S. Filby, D. Simon, M. Shishehbor, F. Forouzandeh","doi":"10.15420/USC.2021.05","DOIUrl":"https://doi.org/10.15420/USC.2021.05","url":null,"abstract":"In patients presenting with ST-elevation MI, prompt primary coronary intervention is the preferred treatment modality. Several studies have described improved outcomes in patients with door-to-balloon (D2B) and symptom onset-to-balloon (OTB) times of less than 2 hours, but the specific implications of the coronavirus disease 2019 (COVID-19) pandemic on D2B and OTB times are not well-known. This review aims to evaluate the impact of COVID-19 on D2B time and elucidate both the factors that delay D2B time and strategies to improve D2B time in the contemporary era. The search was directed to identify articles discussing the significance of D2B times before and during COVID-19, from the initialization of the database to December 1, 2020. The majority of studies found that onset-of-symptom to hospital arrival time increased in the COVID-19 era, whereas D2B time and mortality were unchanged in some studies and increased in others.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45460821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Transcatheter Tricuspid Valve Intervention: Current Perspective 经导管三尖瓣介入治疗的现状
US Cardiology Review Pub Date : 2021-06-30 DOI: 10.15420/usc.2020.26
T. Simard, M. Eleid
{"title":"Transcatheter Tricuspid Valve Intervention: Current Perspective","authors":"T. Simard, M. Eleid","doi":"10.15420/usc.2020.26","DOIUrl":"https://doi.org/10.15420/usc.2020.26","url":null,"abstract":"Tricuspid regurgitation (TR) adversely impacts both quality of life and long-term survival, which generates interest in therapeutic approaches to mitigate these effects. Historically, therapeutic options for TR were limited to surgical approaches, which are often complicated by significant morbidity and mortality in elderly patients with multiple comorbidities. This gap in therapeutic options led to the rapid evolution of transcatheter tricuspid valve intervention (TTVI), with a wide variety of approaches pursued and early results suggesting that TTVI improves clinical outcomes. Numerous strategies, including edge-to-edge repair, annular reduction, spacers, caval valve implantation, and transcatheter tricuspid valve replacement form the basis of TTVI today. In this review, the authors discuss the current state of each approach.","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43128578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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