US Cardiology ReviewPub Date : 2026-09-22eCollection Date: 2026-01-01DOI: 10.15420/usc.2025.18
Adam L Gottula, Kari L Gorder, Michael J Lauria, William Hallinan, Eric Thomas, Katherine L Wood, Mir B Basir, Alexander G Truesdell
{"title":"Cardiogenic Shock Systems of Care Best Practices, Part 3: Regionalization of Care, Organizational Components, and Critical Care Transport Medicine.","authors":"Adam L Gottula, Kari L Gorder, Michael J Lauria, William Hallinan, Eric Thomas, Katherine L Wood, Mir B Basir, Alexander G Truesdell","doi":"10.15420/usc.2025.18","DOIUrl":"https://doi.org/10.15420/usc.2025.18","url":null,"abstract":"<p><p>This paper explores the regionalization of care, organizational components, and critical care transport medicine for cardiogenic shock patients. It discusses the establishment of cardiogenic shock centers, interdisciplinary collaboration, and the necessary infrastructure to ensure optimal patient outcomes. Emphasizing the importance of a regionalized treatment algorithm and transfer strategy, the paper builds on the foundational understanding of managing cardiogenic shock, aiming to provide a comprehensive framework for advanced management and regional transfer strategies essential for high-risk patients.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e23"},"PeriodicalIF":0.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-09-22eCollection Date: 2026-01-01DOI: 10.15420/usc.2025.16
Michael J Lauria, Adam L Gottula, William Hallinan, Eric Thomas, Katherine L Wood, Mir B Basir, Alexander G Truesdell, Kari L Gorder
{"title":"Cardiogenic Shock Systems of Care Best Practices. Part 1: Prehospital and Emergency Department Evaluation and Management.","authors":"Michael J Lauria, Adam L Gottula, William Hallinan, Eric Thomas, Katherine L Wood, Mir B Basir, Alexander G Truesdell, Kari L Gorder","doi":"10.15420/usc.2025.16","DOIUrl":"https://doi.org/10.15420/usc.2025.16","url":null,"abstract":"<p><p>This paper explores best practices for the prehospital and emergency department evaluation and management of cardiogenic shock, a critical condition marked by high mortality rates, within a contemporary cardiogenic shock system of care. It highlights the significance of early identification and immediate intervention to prevent irreversible cardiac and non-cardiac organ damage. Emphasizing multidisciplinary team-based care and data-driven insights, the paper details optimal strategies for managing cardiogenic shock from initial contact, noting challenges in prehospital identification and treatment due to patient and disease heterogeneity and the variability in response capabilities of prehospital teams.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e21"},"PeriodicalIF":0.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-09-22eCollection Date: 2026-01-01DOI: 10.15420/usc.2025.17
Kari L Gorder, Michael J Lauria, William Hallinan, Eric Thomas, Katherine L Wood, Mir B Basir, Alexander G Truesdell, Adam L Gottula
{"title":"Cardiogenic Shock Systems of Care Best Practices. Part 2: The Shock Team and Inpatient Management.","authors":"Kari L Gorder, Michael J Lauria, William Hallinan, Eric Thomas, Katherine L Wood, Mir B Basir, Alexander G Truesdell, Adam L Gottula","doi":"10.15420/usc.2025.17","DOIUrl":"https://doi.org/10.15420/usc.2025.17","url":null,"abstract":"<p><p>This paper describes the contemporary inpatient management of cardiogenic shock, including critical care management and the use of mechanical circulatory support as part of a cardiogenic shock system of care. It highlights the importance of multidisciplinary shock teams for improving patient outcomes through advanced mechanical circulatory support systems and critical care management strategies. Drawing on successful models in trauma care, the paper discusses the evolution of specialized teams, the reduction of care variability, and the enhancement of survival rates through standardized best practices. A case study illustrates the effective implementation of these principles, resulting in improved short-term survival and long-term recovery for patients.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e22"},"PeriodicalIF":0.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-09-11eCollection Date: 2026-01-01DOI: 10.15420/usc.2026.24
Keerthi T Gondi, Gustavo Hernandez, Ki Park
{"title":"Percutaneous Coronary Intervention for Coronary Artery Disease in Patients Undergoing Transcatheter Aortic Valve Replacement: Perspective on the PRO-TAVI Trial.","authors":"Keerthi T Gondi, Gustavo Hernandez, Ki Park","doi":"10.15420/usc.2026.24","DOIUrl":"10.15420/usc.2026.24","url":null,"abstract":"","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e20"},"PeriodicalIF":0.0,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-09-11eCollection Date: 2026-01-01DOI: 10.15420/usc.2025.21
Gabriela Maria Diaz, Julia Ossi, Mariana Garcia
{"title":"Multimodal Imaging in MI with Non-obstructive Coronary Arteries: Unraveling Pathophysiology and Guiding Management.","authors":"Gabriela Maria Diaz, Julia Ossi, Mariana Garcia","doi":"10.15420/usc.2025.21","DOIUrl":"https://doi.org/10.15420/usc.2025.21","url":null,"abstract":"<p><p>MI with non-obstructive coronary arteries (MINOCA) represents a complex, heterogeneous syndrome with variable underlying mechanisms and substantial morbidity. The role of multimodality cardiovascular imaging in clarifying etiology and guiding therapy continues to evolve. Multimodality imaging offers insights into the pathophysiology of MINOCA. Coronary angiography remains the first-line diagnostic tool to exclude obstructive coronary disease, while adjunctive functional testing can identify epicardial or microvascular vasospasm. Echocardiography evaluates ventricular function, wall motion abnormalities, and embolic sources, whereas cardiac MRI differentiates ischemic from non-ischemic injury, detects myocardial edema, and assesses scar burden. Intravascular imaging can detect plaque rupture, erosion, or thrombus. Nuclear imaging modalities provide a quantitative assessment of microvascular perfusion and coronary flow reserve. Coronary CT angiography may further characterize non-obstructive plaque or coronary anomalies. This review summarizes the comprehensive evaluation of MINOCA. Integrating modalities can improve diagnostic accuracy, identify the underlying etiology, guide targeted therapy, and inform prognosis, underscoring the importance of a multimodal imaging approach.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e19"},"PeriodicalIF":0.0,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-09-04eCollection Date: 2026-01-01DOI: 10.15420/usc.2026.23
Claudiu Mihai Ciuciureanu, Ricardo Orlando Escarcega, Stefan Milutinovic, Richard A Chazal, Kamaldeep Singh
{"title":"Percutaneous Coil Embolization of an Anomalous Coronary Artery-Pulmonary Artery Fistula with Aneurysmal Segment.","authors":"Claudiu Mihai Ciuciureanu, Ricardo Orlando Escarcega, Stefan Milutinovic, Richard A Chazal, Kamaldeep Singh","doi":"10.15420/usc.2026.23","DOIUrl":"10.15420/usc.2026.23","url":null,"abstract":"","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e18"},"PeriodicalIF":0.0,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13595272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-09-01eCollection Date: 2026-01-01DOI: 10.15420/usc.2025.23
Jonathan Scott Dowell, Nimesh Patel
{"title":"Discontinuing Oral Anticoagulation after Atrial Fibrillation Ablation: Time for a Paradigm Shift?","authors":"Jonathan Scott Dowell, Nimesh Patel","doi":"10.15420/usc.2025.23","DOIUrl":"10.15420/usc.2025.23","url":null,"abstract":"<p><p>AF is the most common arrhythmia in adult patients and frequently requires oral anticoagulation (OAC) for stroke prevention. Catheter ablation for AF has become an increasingly popular rhythm control strategy, although there is no clear consensus on the safety of OAC discontinuation after ablation. While current guidelines recommend continuing OAC after AF ablation based on CHA<sub>2</sub>DS<sub>2</sub>-VASc score, recent evidence suggests it may be safe and beneficial to discontinue OAC in appropriate populations. Catheter ablation has been shown to reduce both overall AF burden and stroke risk in large prospective studies. The ALONE-AF and OCEAN trials demonstrated that discontinuing OAC after AF ablation did not increase stroke incidence, but did reduce clinically significant bleeding events. A possible framework for discontinuing OAC could involve a risk-stratified approach to guide ambulatory monitoring for AF recurrence. In summary, OAC discontinuation may be considered in patients with no or minimal evidence of AF recurrence after catheter ablation.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e17"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13595265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-08-17eCollection Date: 2026-01-01DOI: 10.15420/usc.2026.05
Justin Haloot, Alexis Tumolo
{"title":"Electrophysiology Laboratory Survival Guide Part 1: Electrogram Basics, Catheters, and Basic Intervals.","authors":"Justin Haloot, Alexis Tumolo","doi":"10.15420/usc.2026.05","DOIUrl":"https://doi.org/10.15420/usc.2026.05","url":null,"abstract":"<p><p>The term 'cardiac electrogram' (EGM) was initially used to describe the surface ECG, but now EGMs represent the electrical potential within the immediate vicinity of a catheter (including pacemaker and implantable cardioverter defibrillator lead) within the heart. These EGMs are generated from electrodes on catheters that are placed in different regions of the heart: the right atrium, the right ventricle, in the coronary sinus, and near the His bundle. These EGMs, in conjunction with a surface ECG, can then be used to study the timing of electrical activity within the heart, as well as arrhythmias in the cardiac electrophysiology (EP) lab. The goals of this article are to give readers the basics of EGMs, the basics of cardiac EP catheters, and the placement of EP catheters in the heart, and to introduce readers to EGMs and intervals measured.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e15"},"PeriodicalIF":0.0,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13573017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-08-17eCollection Date: 2026-01-01DOI: 10.15420/usc.2026.04
Justin Haloot, Paul Schurmann
{"title":"Electrophysiology Laboratory Survival Guide Part 2: Introduction to Intracardiac Echocardiography in the Electrophysiology Laboratory.","authors":"Justin Haloot, Paul Schurmann","doi":"10.15420/usc.2026.04","DOIUrl":"10.15420/usc.2026.04","url":null,"abstract":"<p><p>Intracardiac echocardiography (ICE) is a catheter-based ultrasound probe that is used in the cardiac electrophysiology laboratory for real-time assessment of cardiac structures during electrophysiological studies. ICE requires additional vascular access, but provides real-time intracardiac analysis of cardiac structures. The imaging sector of ICE creates a fan from the side of the catheter tip that is perpendicular along the long axis of the ICE catheter, different from standard echocardiographic images. The near-field image shows structures proximal along the long axis of the catheter, whereas the far-field image shows structures distal along the long axis. The home view for ICE imaging has the catheter within the right atrium facing the tricuspid valve in the neutral position, with additional views obtained with clockwise rotation of the catheter. Careful attention is required when advancing the catheter in the body and interpreting the ICE images.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e16"},"PeriodicalIF":0.0,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13573008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
US Cardiology ReviewPub Date : 2026-08-05eCollection Date: 2026-01-01DOI: 10.15420/usc.2025.20
Rebecca S Steinberg, Ritika Tuli, Shivani Reddy, Rafael Toro-Manotas, Natalie Marrero, Dinu V Balanescu, Manu Murali Mysore
{"title":"Beyond Hyperglycemia: The Role of Sodium-Glucose Cotransporter 2 Inhibitors in Cancer Treatment-related Cardiac Dysfunction.","authors":"Rebecca S Steinberg, Ritika Tuli, Shivani Reddy, Rafael Toro-Manotas, Natalie Marrero, Dinu V Balanescu, Manu Murali Mysore","doi":"10.15420/usc.2025.20","DOIUrl":"10.15420/usc.2025.20","url":null,"abstract":"<p><p>Recent data suggest that sodium-glucose cotransporter 2 inhibitors have cardioprotective benefits. This effect may extend towards cardioprotection in cancer therapy-related cardiac dysfunction, with proposed mechanisms extending beyond glycemic control to include anti-inflammatory effects, oxidative stress reduction, and metabolic reprogramming. This review synthesizes potential mechanisms, observational data, and emerging trial evidence to support sodium-glucose cotransporter 2 inhibitors as a primary prevention strategy for cancer therapy-related cardiac dysfunction, particularly in anthracycline-exposed populations.</p>","PeriodicalId":37809,"journal":{"name":"US Cardiology Review","volume":"20 ","pages":"e14"},"PeriodicalIF":0.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13495110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}