Dominik D Mattioli, Geb W Thomas, Steven A Long, Marcus Tatum, Donald D Anderson
{"title":"Minimally Trained Analysts Can Perform Fast, Objective Assessment of Orthopedic Technical Skill from Fluoroscopic Images.","authors":"Dominik D Mattioli, Geb W Thomas, Steven A Long, Marcus Tatum, Donald D Anderson","doi":"10.1080/24725579.2022.2035022","DOIUrl":"10.1080/24725579.2022.2035022","url":null,"abstract":"<p><p>Skill assessment in orthopedics has traditionally relied on subjective impressions from a supervising surgeon. The feedback derived from these tools may be limited by bias and other practical issues. Objective analysis of intraoperative fluoroscopic images offers an inexpensive, repeatable, and precise assessment strategy without bias. Assessors generally refrain from using the scores of images obtained throughout the operation to evaluate skill for practical reasons. A new system was designed to facilitate rapid analysis of this fluoroscopy via minimally trained analysts. Four expert and four novice analysts independently measured one objective metric for skill using both a custom analysis software and a commercial alternative. Analysts were able to measure the objective metric three times faster when using the custom software, and without a practical difference in accuracy in comparison to the expert analysts using the commercial software. These results suggest that a well-designed fluoroscopy analysis system can facilitate inexpensive, reliable, and objective assessment of surgical skills.</p>","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 3","pages":"212-220"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488091/pdf/nihms-1832409.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10797323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automatic atrial fibrillation detection from short ECG signals: A hybrid deep learning approach","authors":"Xiaodan Wu, Z. Sui, Chao-Hsien Chu, Guanjie Huang","doi":"10.1080/24725579.2021.1919249","DOIUrl":"https://doi.org/10.1080/24725579.2021.1919249","url":null,"abstract":"Abstract Atrial fibrillation (AF) is one of the most common arrhythmic complications. Recently, researchers have attempted to use deep learning models, such as convolution neural networks (CNN) and/or Long Short-Term Memory (LSTM) neural networks to alleviate the tedious and time-consuming feature extraction process and achieve good classification results. In this paper we propose a hybrid CNN-LSTM model and use the short ECG signal from the PhysioNet/CinC Challenges 2017 dataset to explore and evaluate the relative performance of four data mining algorithms and three deep learning architectures. The original ECG signal, clinical diagnostic features and 169 features based on time domain, frequency domain and non-linear heart rate variability indicators were used for comparative experiments. The results show that with proper design and tuning, the Hybrid CNN-LSTM model performed much better than other benchmarked algorithms. It achieves 97.42% accuracy, 95.65% sensitivity, 97.14% specificity, 0.99 AUC (Area under the ROC curve) value and 0.98 F1 score. In general, with proper design and configuration, deep learning can be effective for automatic AF detection while data mining methods require domain knowledge and an extensive feature extraction and selection process to get satisfactory results. However, most machine learning algorithms, including deep learning models, perform the task as a black box, making it almost impossible to determine what features in the signal are critical to the analysis.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"1 - 19"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46086205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lan Jiang, Yu Ding, Melissa A. Sutherland, M. K. Hutchinson, Chuheng Zhang, Bing Si
{"title":"A novel sparse model-based algorithm to cluster categorical data for improved health screening and public health promotion","authors":"Lan Jiang, Yu Ding, Melissa A. Sutherland, M. K. Hutchinson, Chuheng Zhang, Bing Si","doi":"10.1080/24725579.2021.1980467","DOIUrl":"https://doi.org/10.1080/24725579.2021.1980467","url":null,"abstract":"Abstract Screening for interpersonal violence is critical to mitigate the consequences of violence and improve women’s health. Current guidelines recommend that health care providers screen all women for experiences of violence. Despite these recommendations, studies have noted a large variation in provider-reported interpersonal violence screening rates ranging from 10% to 90%. Given the disparity in screening rates, identifying variables correlated with providers’ screening practices is an important contribution. A survey of healthcare providers previously collected was utilized for this analysis and consisted of the providers’ socio-demographics, attitudes and beliefs, practice environment characteristics as well as self-reported screening practices. The objective of the study was to stratify healthcare providers into relatively homogeneous clusters based on mixed types of categorical nominal and ordinal variables and correlate the identified clusters with the violence screening rates. This paper proposes a sparse categorical Factor Mixture Model (sc-FMM) to cluster a large number of categorical variables, in which an norm was used for variable selection. An Expectation Maximization framework integrated with Gauss-Hermite approximation was developed for model estimation. Simulation studies show significantly better performance of sc-FMM than competing methods. sc-FMM was applied to identify clusters/subgroups of healthcare providers. The identified clusters were further correlated with interpersonal violence screening rates. The findings reveal how the providers’ screening rate for interpersonal violence are associated with multi-source impacting factors which inform the formation of policy and intervention development to promote the uptake of routine screening for interpersonal violence in women.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"137 - 149"},"PeriodicalIF":0.0,"publicationDate":"2021-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60128539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of prescriber experience and continuity on adverse drug reactions in hospitalized cancer patients","authors":"Yue Tang, Jingui Xie, Aizong Shen, Lin-Lin Liu, Fei Zhai, Changfang Fu","doi":"10.1080/24725579.2021.1955777","DOIUrl":"https://doi.org/10.1080/24725579.2021.1955777","url":null,"abstract":"Abstract Cancer patients suffer severely from bodily damage due to malignant neoplasms and live a life of low quality, while the occurrence of adverse drug reactions (ADRs) worsens these conditions. Risk factors associated with ADRs have been long discussed in the literature, yet few studies considered prescriber-related risks. This study filled the gap by examining the ADR risk of prescriber-related factors from two dimensions: prescriber experience and prescriber continuity. We conducted a logistic regression analysis to investigate the effects. The data for analysis contained 34,474 inpatient admissions linked to 2,750,685 medication orders. We found that both experienced prescriber and prescriber continuity are related to lower ADR risk. Our results also revealed that the involvement of more experienced physicians in the prescribing process could mitigate the harmful effects of prescriber non-continuity on ADRs.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"89 - 100"},"PeriodicalIF":0.0,"publicationDate":"2021-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43660268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel self-adaptive convolutional neural network model using spatial pyramid pooling for 3D lung nodule computer-aided diagnosis","authors":"Qianqian Zhang, Sangwon Yoon","doi":"10.1080/24725579.2021.1953638","DOIUrl":"https://doi.org/10.1080/24725579.2021.1953638","url":null,"abstract":"Abstract This research proposes a novel self-adaptive convolutional neural network (Adap-Net) model for lung nodule diagnosis on 3D computed tomography (CT) images. Lung cancer is one of the most common cancers with a high mortality rate. Therefore, there is an urgent need to diagnose lung nodules to improve the survival rate, which is challenging because of the nodule heterogeneity and the lack of annotated lung nodule images. Prevailing research for lung nodule diagnosis usually ignores the nodule heterogeneity problem and enlarges the model complexity that degrades the lung nodule diagnosis performance given limited annotated training samples. To overcome the challenges, a transverse layer pooling (TLP) algorithm is proposed and the spatial pyramid pooling (SPP) scheme is integrated, which makes it possible to adaptively extract equal-dimensional feature representations from arbitrary-sized 3D lung nodule images. Meanwhile, the TLP algorithm introduces a layer compression architecture that dramatically reduces the model complexity. Moreover, K-means clustering is adopted to assign appropriate input image sizes for each lung nodule, allowing the mini-batch-based model training. The proposed Adap-Net is comprehensively evaluated and compared to other deep learning (DL) models using 3D CT images from a public dataset. Experimental results show that the proposed Adap-Net model improves the lung nodule diagnosis accuracy up to 12.12% with less than 10% of parameters that are involved in other DL models. In practice, the proposed Adap-Net model can offer complementary opinions in computer-aided diagnosis (CAD) systems as a supportive tool for radiologists and physicians in the medical image interpretation, analysis, and diagnosis process.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"75 - 88"},"PeriodicalIF":0.0,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43131044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep spatio-temporal sparse decomposition for trend prediction and anomaly detection in cardiac electrical conduction","authors":"Xinyu Zhao, Hao Yan, Zhiyong Hu, D. Du","doi":"10.1080/24725579.2021.1982081","DOIUrl":"https://doi.org/10.1080/24725579.2021.1982081","url":null,"abstract":"Abstract Electrical conduction among cardiac tissue is commonly modeled with partial differential equations, i.e., reaction-diffusion equation, where the reaction term describes cellular stimulation and diffusion term describes electrical propagation. Detecting and identifying of cardiac cells that produce abnormal electrical impulses in such nonlinear dynamic systems are important for efficient treatment and planning. To model the nonlinear dynamics, simulation has been widely used in both cardiac research and clinical study to investigate cardiac disease mechanisms and develop new treatment designs. However, existing cardiac models have a great level of complexity, and the simulation is often time-consuming. We propose a deep spatio-temporal sparse decomposition (DSTSD) approach to bypass the time-consuming cardiac partial differential equations with the deep spatio-temporal model and detect the time and location of the anomaly (i.e., malfunctioning cardiac cells). This approach is validated from the data set generated from the Courtemanche-Ramirez-Nattel (CRN) model, which is widely used to model the propagation of the transmembrane potential across the cross neuron membrane. The proposed DSTSD achieved the best accuracy in terms of spatio-temporal mean trend prediction and anomaly detection.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"150 - 164"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49275603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-centric surgeons’ case mix problem","authors":"Renato de Matta","doi":"10.1080/24725579.2021.1965676","DOIUrl":"https://doi.org/10.1080/24725579.2021.1965676","url":null,"abstract":"Abstract This paper studies a single-period tactical planning problem to find the surgeons’ case mix of a hospital surgical unit such that the total patient value per dollar spent on healthcare resources (the TPV) is maximized. We represent the relationship between the surgeons’ volume and patient outcomes using the learning curve. We formulate the problem as a nonlinear integer programming model. The problem belongs to the class of nonquadratic transportation problems in which it is proven that no algorithm solving the problem in strongly polynomial time exists. We develop a Lagrangian-based heuristic solution approach that exploits the special structure of the problem. Using simulated and real data, we show that the diversity in surgeons’ experience complements a surgical unit in a way that good patient outcomes of experienced surgeons counterbalance the average but improving patient outcomes of less experienced surgeons while the less experienced surgeons gain more experience.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"111 - 129"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45519283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A modified SIR model equivalent to a generalized logistic model, with standard logistic or log-logistic approximations","authors":"D. E. Clark, G. Welch, J. Peck","doi":"10.1080/24725579.2021.1968547","DOIUrl":"https://doi.org/10.1080/24725579.2021.1968547","url":null,"abstract":"Abstract A modified version of the three-compartment susceptible-infectious-removed (SIR) epidemic model can be expressed exactly using a specific generalization of the logistic distribution, and its parameters can be estimated from epidemic surveillance data. The population proportion remaining Susceptible may be approximated using the inverse of a standard cumulative logistic distribution, while the population proportion actively Infectious may be approximated using the density of a logistic or log-logistic distribution. This knowledge may enable rapid local disease modeling without specialized skills. Highlights A modification of the three-compartment SIR model can be solved exactly in terms of a specific generalization of the logistic distribution The generalized logistic solution can be approximated using standard logistic and/or log-logistic distributions Surveillance data from an emerging epidemic, often initially modeled with standard logistic or log-logistic curves, can be used to derive parameters for an underlying modified SIR model","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"130 - 136"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47100083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Auður Anna Jónsdóttir, L. Kessler, S. Rim, Ji-Eun Kim
{"title":"What patients and care partners want in a wearable dialysis device: a mixed-methods study","authors":"Auður Anna Jónsdóttir, L. Kessler, S. Rim, Ji-Eun Kim","doi":"10.1080/24725579.2021.1958273","DOIUrl":"https://doi.org/10.1080/24725579.2021.1958273","url":null,"abstract":"Abstract Few studies have explored the similarities and differences between patients’ and care partners’ perspectives in terms of their ideal dialysis procedure and desired outcomes. As part of a project to improve the quality of life of patients with end-stage renal disease, we elicited unbiased feedback from both patients and care partners regarding the design of a wearable dialysis device tailored to meet users’ clinical needs. We interviewed 24 hemodialysis patients and 12 hemodialysis care partners using a mixed-methods approach of open-ended and rank-order questions. Inductive content analysis showed that both patients and care partners preferred a wearable dialysis device that a patient could carry on their upper body, particularly on their back or shoulder, or wear as a vest. Analysis of responses to the rank-order questions showed a significant preference for a vest design. Operational simplicity and compactness were the attributes most frequently mentioned in response to the open-ended questions, while the accuracy of the device was ranked as significantly more important than ease of attachment, comfort, simplicity, size, or invisibility in response to the rank-order questions. The findings from this study will help to ensure that new wearable dialysis devices are designed in accordance with patients’ and care partners’ preferences.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"101 - 110"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46643942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multidisciplinary efforts in combating nonadherence to medication and health care interventions: Opportunities and challenges for operations researchers","authors":"A. Prakash, C. Vega, V. Diaby, Xiang Zhong","doi":"10.1080/24725579.2021.1953639","DOIUrl":"https://doi.org/10.1080/24725579.2021.1953639","url":null,"abstract":"Abstract Chronic diseases are a growing concern in public health. Lack of adherence to medications and health care interventions is a major factor behind the worsening of chronic disease outcomes and large medical costs. As a result, there is a critical need to identify structural, systematic, and patient-centric barriers to adherence. Similarly important is the development of models and deployable strategies to ensure effective delivery of care so that clinical and economic outcomes are optimized. This commentary review explores the research on nonadherence of patients with chronic diseases and other non-acute conditions to medications and interventions from different disciplinary perspectives, including medicine/pharmacy, pharmacoeconomics, behavioral economics, operations research (OR), and data analytics (DA). Although a spate of works has been conducted in the medicine and pharmacy fields, the contribution of OR/DA to medication/intervention nonadherence is limited. Given the technological advancement and the increasing understanding of nonadherence, we believe that OR/DA can play an essential role in encapsulating the domain knowledge and catalyzing the development of patient-centric solutions. We discuss the challenges and opportunities presented to OR/DA researchers and conclude the commentary with a discussion on new interdisciplinary research directions that can contribute to solving the nonadherence puzzle.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"11 1","pages":"255 - 270"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42647310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}