Revista de Patologia Respiratoria最新文献

{"title":"Análisis de la proteína C reactiva en la población fumadora sana y con EPOC e influencia de las comorbilidades y del tiempo de abandono del tabaco","authors":"M.C. Villa-Corbatón ,&nbsp;L. Callol-Sánchez ,&nbsp;J. Medina-Font ,&nbsp;J. Gómez de Terreros-Sánchez ,&nbsp;C. Gutiérrez-Ortega ,&nbsp;J. Gómez de Terreros-Caro","doi":"10.1016/S1576-9895(12)70154-6","DOIUrl":"10.1016/S1576-9895(12)70154-6","url":null,"abstract":"<div><h3>Objective</h3><p>The smoking habit increases the C reactive protein in the serum. Values are studied in different populations: healthy (exsmokers, smokers and nonsmokers), chronic bronchitis and chronic obstructive pulmonary disease (COPD) in different stages; in addition the influence according to the time of abandonment of the tobacco and the associate comorbidities.</p></div><div><h3>Material and methods</h3><p>Descriptive-transversal analysis. 401 persons we studied: 106 healthy not smokers (HNS), 104 healthy smokers (HS), 95 healthy nonsmoker (HN), 30 with chronic bronchitis, 30 with incipient COPD (COPDi) and 36 with advanced COPD (COPDa), with ages included between 45 and 80 years old, being detrmined CRP and the associate comorbidities.</p></div><div><h3>Results</h3><p>CRP's values were: 1.98 (2.1)<!--> <!-->mg/l in HN; 3.35 (4.39)<!--> <!-->mg/l in HS; 2 (2.2)<!--> <!-->mg/l in HE; 3 (3.8)<!--> <!-->mg/l in chronic bronchitis; 3.40 (2.23) in COPDi and 5.94 (1.76) in COPDa. The CRP in chronic bronchitis and COPD falls to 2.7 (6.8) after five years of abandonment of the tobacco, remaining constant after. There exist significant differences between the HS and HN populations, and between chronic bronchitis and COPD after five years of abstinence with the population HN (p=0.003). There are not significant differences between HE and HN (p<!--> <!-->&gt;<!--> <!-->0.05); between population HS and the population with chronic bronchitis and COPDi (p<!--> <!-->&gt;<!--> <!-->0.05), and between COPD's different stages and the indexes of comorbiditie.</p></div><div><h3>Conclusions</h3><p>The value of the CRP in the HS population is similar to that on the chronic bronchitis and COPDi population, but higher to that of the HN. After the abandon of the smoking habit, in HS the CRP returns to the value of the HN population. In the populations with pathologies is significantly elevated as compared to HN and not return to the HN level after five years of abstinence. Their level is independent of comorbidity index. The detection level of inflammatory disease is at a value of PCR: 3<!--> <!-->mg/l.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 4","pages":"Pages 104-110"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70154-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"El uso de los biomarcadores de inflamación en la vía aérea en el manejo del asma","authors":"S. Sánchez-Cuéllar,&nbsp;J. Ancochea Bermúdez","doi":"10.1016/S1576-9895(12)70157-1","DOIUrl":"10.1016/S1576-9895(12)70157-1","url":null,"abstract":"<div><p>Biological markers are being used in the diagnosis and treatment of disease as prevalent as cardiovascular or cancer. Biomarkers are a useful in clinical practice as a non invasive methods for the accurate diagnosis of the disease, monitor disease and create personalized treatment regimes. Asthma is a heterogeneous disease with different phenotypes. Pulmonary function test are most often used to confirm the diagnosis, but not reflect the pathological processes responsible for different phenotypes that present the disease. Inhaled corticosteroids and beta 2 agonists have been mainstay of asthma therapy for over 30 years, but the heterogeneity of the disease means not all asthmatics respond to the same treatment. Biomarkers are useful tools to identify these specific phenotypes. This review focuses on the utility of biomarkers of inflammation of the airway in the management of asthma patients obtained by noninvasive tecniques including sputum, exhaled breath or serum.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 4","pages":"Pages 129-135"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70157-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56526490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importancia para una revista científica de encontrarse incluida en las grandes bases de datos internacionales","authors":"A. Alonso Arroyo ,&nbsp;R. Aleixandre Benavent","doi":"10.1016/S1576-9895(12)70153-4","DOIUrl":"10.1016/S1576-9895(12)70153-4","url":null,"abstract":"","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 4","pages":"Pages 101-103"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70153-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leiomiomatosis benigna pulmonar metastatizante","authors":"D. Palafox ,&nbsp;J. Palafox ,&nbsp;G. Aquino ,&nbsp;W.L. Dajer-Fadel","doi":"10.1016/S1576-9895(12)70149-2","DOIUrl":"10.1016/S1576-9895(12)70149-2","url":null,"abstract":"<div><p>Pulmonary benign metastasising leiomyomatosis is an uncommon disease characterized by the presence of pulmonary leiomyomas, in the absence of malignancy criteria in a patient with previous uterin leiomyomatosis. The disease is very uncommon and should be considered amongst the differential diagnosis of pulmonary benign tumors. Due to the challenge that represents to health care providers specialized in respiratory pathology in the diagnosis and management of these type of patients, we present the case of a patient with hysterectomy for uterin myomatosis in which the diagnosis of pulmonary benign metastasising leiomyomatosis was established and treated successfully.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 3","pages":"Pages 85-88"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70149-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vacuna antineumocócica","authors":"J.A. Riesco Miranda,&nbsp;M. Torres González,&nbsp;D. del Puerto García","doi":"10.1016/S1576-9895(12)70146-7","DOIUrl":"https://doi.org/10.1016/S1576-9895(12)70146-7","url":null,"abstract":"","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 3","pages":"Pages 71-73"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70146-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91622392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Derrame pleural en pacientes hospitalizados en la era de la vacuna antineumocócica heptavalente","authors":"E. Villalobos Pinto,&nbsp;A. Pérez Pérez,&nbsp;J. Cano Fernández,&nbsp;P. Flores Pérez,&nbsp;M. Sánchez–Bayle","doi":"10.1016/S1576-9895(12)70147-9","DOIUrl":"10.1016/S1576-9895(12)70147-9","url":null,"abstract":"<div><p><em>Introduction</em>: Invasive pneumococcal disease is one of the diseases with higher morbidity and mortality in children. Despite expectations created, we discuss the role of the heptavalent vaccine in the incidence of complicates pneumonia. Our goal is to determine if it has increased in our hospital.</p><p><em>Patients and methods</em>: We studied 9068 patients admitted with the diagnosis of pneumonia in the Hospital Niño Jesús between 1996 and 2010. A retrospective, observational study, analyzing the total or partial introduction of the vaccine.</p><p><em>Results</em>: Sample segregation in 3 groups according to the non introduction and the total or partial introduction of the vaccine. We confirmed an increase in pleural effusion (p&lt; 0.005) in vaccine groups.</p><p><em>Conclusions</em>: After the introduction of heptavalent pneumococcal vaccine it has been found in our sample an increase in complicated pneumonia with pleural effusion.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 3","pages":"Pages 74-77"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70147-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hernia pulmonar intercostal espontánea secundaria a cuadro de tos","authors":"I. Martínez Serna,&nbsp;M.A. Mariscal de Alba,&nbsp;F. Hermoso Alarza,&nbsp;R.J. Ávila Martínez,&nbsp;M.C. Marrón Fernández,&nbsp;J.C. Meneses Pardo","doi":"10.1016/S1576-9895(12)70150-9","DOIUrl":"10.1016/S1576-9895(12)70150-9","url":null,"abstract":"<div><p>Lung hernias are rare entities and are primarily related to chest trauma or previous surgery. Spontaneous lung hernias are even more uncommon. We describe three cases of spontaneous intercostal pulmonary hernia, its evaluation and treatment in all its forms, from the conservative management in small hernias without significant clinical impact, to surgical treatment, either with primary closure of the chest wall or using synthetic mesh in larger hernias or in presence of signs of possible complications.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 3","pages":"Pages 89-91"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70150-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selección bibliográfica: asma","authors":"C. Cisneros Serrano ,&nbsp;E. Arias Arias ,&nbsp;J. Fernández-Lahera","doi":"10.1016/S1576-9895(12)70151-0","DOIUrl":"10.1016/S1576-9895(12)70151-0","url":null,"abstract":"","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 3","pages":"Pages 92-95"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70151-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conductas de riesgo en pacientes con síndrome de apneas-hipopneas del sueño: estudio exploratorio en situaciones complejas y dinámicas de tráfico simulado","authors":"L.L. Di Stasi ,&nbsp;C. Díaz–Piedra ,&nbsp;A. Catena ,&nbsp;G. Buela–Casal","doi":"10.1016/S1576-9895(12)70148-0","DOIUrl":"10.1016/S1576-9895(12)70148-0","url":null,"abstract":"<div><p><em>Objective</em>: A large consensus exists within the scientific community with regard to the existence of a high incidence of traffic accidents in people with Sleep Apnea Hypopnea Syndrome (SAHS). However, some aspects of this relationship are still in need of clarification. It has not been possible to show the likely cause of this large rate of accidents, there are possible uncontrolled, confounding factors, and some of the evaluation instruments used have low ecological validity. The goal of the study was to analyze risk behavior during driving in patients with SAS, in a virtual reality setting with simulated traffic.</p><p><em>Material and methods</em>: Evaluation of risk driving behavior was carried out using the Honda Riding Trainer simulator. The participants were 12 patients diagnosed with SAS, treated with continuous positive airway pressure (CPAP), and 12 matched controls. Daytime somnolence, mental fatigue, and levels of activation during the tests, were also evaluated in both groups through the use of questionnaires.</p><p><em>Results</em>: Although patients with SAHS showed higher daytime somnolence, they did not exhibit more risk driving behaviors than the control group. There were no differences in mental fatigue or levels of activation during the simulation.</p><p><em>Conclusion</em>: Unlike the results found in classical studies, when the evaluation is carried out with more ecological tools and the duration of the tests is much shorter, the performance of patients with SAS treated with CPAP does not differ from that of the control group. These findings support the use of CPAP as well as the testing of drivers using virtual simulations in order to obtain a driver's license, especially in high risk populations.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 3","pages":"Pages 78-84"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70148-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interacción paciente-ventilador","authors":"S. López ,&nbsp;B. Artacho ,&nbsp;R. Artacho ,&nbsp;F. García ,&nbsp;J.A. Guzmán ,&nbsp;M. López ,&nbsp;F. Caballero ,&nbsp;E. Campo","doi":"10.1016/S1576-9895(12)70141-8","DOIUrl":"10.1016/S1576-9895(12)70141-8","url":null,"abstract":"<div><p>Mechanical ventilation is a standard therapy in patients admitted to the ICU in a situation of severe acute respiratory failure. Addition to the disruption of gas exchange, the main indication to start is the presence of signs of respiratory muscle fatigue. For mechanical ventilation is essential to succeed and patient ventilator are synchronized, ie the effort that the patient does the inspiration to start being recognized by the fan and it quickly delivers a gas flow, the flow contributed by the fan will need to adapt to patient flow during the delivery of gas and that the fan recognize the termination of inspiratory activity of the patient, complete the delivery of gas and expiratory valve opens to allow the expiration of the patient. This sequence of events that seem so logical, almost never achieved in clinical practice, still common in ventilated patients see some kind of asynchrony. The presence of mismatch or patient-ventilator asynchrony invariably leads to an increased work of breathing, which will defeat the fundamental objective of ventilatory support which is none other than the decrease of the patient work of breathing.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"15 2","pages":"Pages 54-60"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(12)70141-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56525469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}