Journal of Otology最新文献

{"title":"Vestibular rehabilitation in cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS)- A case report","authors":"R.G. Harrell ,&nbsp;A.R. Cassidy ,&nbsp;B.N. Klatt ,&nbsp;P. Hovareshti ,&nbsp;S.L. Whitney","doi":"10.1016/j.joto.2023.06.004","DOIUrl":"10.1016/j.joto.2023.06.004","url":null,"abstract":"<div><h3>Background and purpose</h3><p>Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS) is a neurodegenerative disease of the cerebellum. The disease progression is slow, with up to 25% of people diagnosed needing to use a wheelchair after 15 years from diagnosis. Vestibular symptoms arise from centrally-mediated ocular movement degradation and the reduced vestibular-ocular reflex functioning bilaterally. To date, no report has shown an improvement in VOR gain or gait outcome measures in someone with CANVAS after a course of vestibular physical therapy.</p></div><div><h3>Case description</h3><p>A 65-year-old male, Patient X, first noticed symptoms in his fourth decade of life and was diagnosed with (CANVAS) in his seventh decade. Patient X reported numbness and tingling in his hands and feet, decreased ability to perform daily activities, and several falls.</p></div><div><h3>Intervention</h3><p>Patient X completed a four-month course of vestibular physical therapy, including vestibular ocular reflex exercises, balance training, gait training, and the VestAid application for eye gaze compliance monitoring. The Vestaid application uses eyes and facial recognition software to record the percentage of time that the patient kept their eyes on the target.</p></div><div><h3>Outcomes</h3><p>After vestibular therapy, Patient X had a clinically meaningful improvement in gait speed: from 1.02 m/s to 1.13 m/s and in the Functional Gait Assessment from 20/30 to 27/30. Patient X's eye gaze compliance improved from a median of 43% (range 25–68%) to a median of 67% (58–83%).</p></div><div><h3>Discussion</h3><p>This case study demonstrates that vestibular rehabilitation improved eye gaze compliance and functional outcomes in a person living with CANVAS.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48782997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Location of the AICA influences the severity but not occurrence of ISSNHL: A reappraisal using high-resolution 3 T MRI","authors":"Guoping Zhang ,&nbsp;Hongbin Li ,&nbsp;Zikai Zhao ,&nbsp;Mingxing Zhang ,&nbsp;Jing Zou","doi":"10.1016/j.joto.2023.07.001","DOIUrl":"10.1016/j.joto.2023.07.001","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the potential influence of anatomical variation in the anterior inferior cerebellar artery (AICA) on the occurrence and severity of idiopathic sudden sensorineural hearing loss (ISSNHL).</p></div><div><h3>Methods</h3><p>Ninety ISSNHL patients were enrolled. The anatomical location of the AICA was exhibited using high-resolution magnetic resonance imaging (MRI), and the various AICA types classified by previously reported Chavda and Gorrie methods were analyzed. The severity of hearing loss in the ipsilateral ear among different AICA types was compared.</p></div><div><h3>Results</h3><p>Approximately 85.6% of subjects had unilateral ISSNHL (uISSNHL), and the others had bilateral ISSNHL (bISSNHL). In the uISSNHL group, the ratios of different AICA types were similar between the ipsilateral and contralateral ears. The ratios of the different AICA types in the bISSNHL group were similar to those in the uISSNHL group. In the uISSNHL group, pure tone audiometry (PTA) thresholds at 2 kHz, 4 kHz and 8 kHz of patients with Chavda type II AICA were higher than those of patients with Chavda type I and type III, with a significant difference at 4 kHz between type I and type II. There was a tendency of the PTA threshold in patients with Chavda type II or Gorrie type C to gradually increase from low to high frequency zones.</p></div><div><h3>Conclusion</h3><p>When the AICA enters the IAC (Chavda type II) or crosses between the 7th and 8th cranial nerves (Gorrie type C), the severity and frequency of hearing impairment in ISSNHL but not the occurrence of ISSNHL will be affected.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45136578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intratympanic injection of hydrogel nanodrug for the prevention and treatment of sensorineural hearing loss","authors":"Tianying Zhai ,&nbsp;Pingping Ai ,&nbsp;Zhaohui Tang ,&nbsp;Chaoliang He ,&nbsp;Xuesi Chen ,&nbsp;Shiming Yang ,&nbsp;Nan Wu","doi":"10.1016/j.joto.2023.09.005","DOIUrl":"https://doi.org/10.1016/j.joto.2023.09.005","url":null,"abstract":"<div><p>Safe and efficient drug delivery to the inner ear has always been the focus of prevention and treatment of sensorineural deafness. The rapid development of nanodrug delivery systems based on hydrogel has provided a new opportunity. Among them, thermo-sensitive hydrogels promote the development of new dosage form for intratympanic injection. This smart biomaterial could transform to semisolid phase when the temperature increased. Thermo-sensitive hydrogel nanodrug delivery system is expected to achieve safe, efficient, and sustained inner ear drug administration. This article introduces the key techniques and the latest progress in this field.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49828785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nodular fasciitis of the external auditory canal: Clinical case report and review of the literature","authors":"Adrien Philippart ,&nbsp;Jean-Christophe Degols ,&nbsp;Jacques Vilain","doi":"10.1016/j.joto.2023.09.002","DOIUrl":"https://doi.org/10.1016/j.joto.2023.09.002","url":null,"abstract":"<div><p>Nodular fasciitis is a benign reactive soft tissue tumor arising from fibroblasts and myofibroblasts. Its incidence is low and misdiagnosis is frequent especially for malignant lesions. This can lead to inappropriate and unnecessary invasive treatment. Nodular fasciitis of the external auditory canal is extremely rare. So far, around fifteen cases have been reported. We present here the case of a 90-year-old patient with nodular fasciitis of the right external auditory canal. The lesion extends anteriorly for 6.5 cm and reaches the posterior wall of the maxillary sinus. To our knowledge, this is the first case in the literature of an external auditory canal nodular fasciitis presenting as an inflammatory ear polyp with such a wide extension.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49788825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between age, acceptable noise level, and listening effort in middle-aged and older-aged individuals","authors":"Hemanth Narayan Shetty ,&nbsp;Suma Raju ,&nbsp;Sanjana Singh S","doi":"10.1016/j.joto.2023.09.004","DOIUrl":"https://doi.org/10.1016/j.joto.2023.09.004","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of the study was to evaluate listening effort in adults who experience varied annoyance towards noise.</p></div><div><h3>Materials and methods</h3><p>Fifty native Kannada-speaking adults aged 41–68 years participated. We evaluated the participant's acceptable noise level while listening to speech. Further, a sentence-final word-identification and recall test at 0 dB SNR (less favorable condition) and 4 dB SNR (relatively favorable condition) was used to assess listening effort. The repeat and recall scores were obtained for each condition.</p></div><div><h3>Results</h3><p>The regression model revealed that the listening effort increased by 0.6% at 0 dB SNR and by 0.5% at 4 dB SNR with every one-year advancement in age. Listening effort increased by 0.9% at 0 dB SNR and by 0.7% at 4 dB SNR with every one dB change in the value of Acceptable Noise Level (ANL). At 0 dB SNR and 4 dB SNR, a moderate and mild negative correlation was noted respectively between listening effort and annoyance towards noise when the factor age was controlled.</p></div><div><h3>Conclusion</h3><p>Listening effort increases with age, and its effect is more in less favorable than in relatively favorable conditions. However, if the annoyance towards noise was controlled, the impact of age on listening effort was reduced. Listening effort correlated with the level of annoyance once the age effect was controlled. Furthermore, the listening effort was predicted from the ANL to a moderate degree.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49788823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome","authors":"Christian G. Fritz ,&nbsp;Garrett G. Casale ,&nbsp;Lulia A. Kana ,&nbsp;Robert S. Hong","doi":"10.1016/j.joto.2023.09.006","DOIUrl":"https://doi.org/10.1016/j.joto.2023.09.006","url":null,"abstract":"<div><h3>Purpose</h3><p>To construct a symptoms-based prediction tool to assess the likelihood of superior canal dehiscence (SSCD) on high-resolution CT.</p></div><div><h3>Materials and methods</h3><p>Mathematical modeling was employed to predict radiologic evidence of SSCD at a tertiary neurotology referral center.</p></div><div><h3>Results</h3><p>A total of 168 patients were included, of which 118 had imaging-confirmed SSCD. On univariate analysis significant predictors of SSCD presence were: sound/pressure-induced vertigo (<em>p</em> = 0.006), disequilibrium (<em>p</em> = 0.008), hyperacusis (<em>p</em> = 0.008), and autophony (<em>p</em> = 0.034). Multivariate analysis enabled a 14-point symptom-weighted tool to be developed, wherein a score of ≥6 raised the suspicion of SSCD (≥70% likelihood of being present), R² = 0.853.</p></div><div><h3>Conclusions</h3><p>The likelihood of SSCD on CT scan can be determined with a high degree of certainty based on symptoms recorded at presentation. Using the evidenced-based diagnostic tool validated herein, a score ≥6 with any symptom combination justifies ordering a CT scan.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49788824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Success rates and predictors of outcomes of type I tympanoplasty performed by residents in a teaching tertiary hospital","authors":"Lucas Resende Lucinda Mangia ,&nbsp;Nicole Tássia Amadeu ,&nbsp;Maurício da Silva Oliveira ,&nbsp;Lucas Santin Patzer ,&nbsp;Eduardo de Souza Somensi ,&nbsp;Rogério Hamerschmidt","doi":"10.1016/j.joto.2023.09.003","DOIUrl":"https://doi.org/10.1016/j.joto.2023.09.003","url":null,"abstract":"<div><p>Several technical variations of tympanoplasty have been reported, usually involving the type of graft and/or instruments used. Few studies have focused on the outcome of type-1 tympanoplasty specifically in teaching scenarios. We aimed to describe the results of type-1 tympanoplasty performed by residents, and to investigate potential predictive factors of surgical success. To do so, we did a retrospective analysis of medical records of patients who underwent type-1 tympanoplasty in a tertiary university hospital. We evaluated the tympanic membrane closure and audiometric outcomes during the first year of follow-up, and compared the results according to some clinical and surgical factors. 130 operated ears were included in the study. The closure rate reached 84.12% after one month and 72.72% after twelve months of surgery. The mean air-bone gap was 22.98 dB preoperatively, and reached 10.55 dB after surgery. Perforation closure rates were 85% and 57.14% for those operated by endoscopic and microscopic-assisted approaches, respectively (p = 0.004). The use of cartilage grafts and time without otorrhea of more than three months prior to surgery were also predictors of surgical success (p = 0.002 and 0.041, respectively). Gender, age, perforation size, contralateral disease, operated side, reoperation, and degree of hearing loss did not significantly interfere with outcomes. Tympanoplasty showed good overall results when performed by residents, although inferior to those reported by experienced surgeons. The use of the endoscope, cartilage grafting, and longer preoperative time without otorrhea were predictors of surgical success in this scenario.</p></div><div><h3>Level of evidence</h3><p>IIB.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49788821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential advantages of musical backgrounds on binaural integration and interaction skills in instrumentalists, vocalists, and non-musicians","authors":"Kavassery Venkateswaran Nisha,&nbsp;Adya Parmar,&nbsp;Chandana Shivaiah,&nbsp;Prashanth Prabhu","doi":"10.1016/j.joto.2023.06.003","DOIUrl":"10.1016/j.joto.2023.06.003","url":null,"abstract":"<div><h3>Background</h3><p>Musical perception requires a host of skills. Instrumental musicians place greater emphasis on motor coordination, whereas vocal musicians rehearse vocal sounds. The study explored the differential advantages of musical background on binaural integration and interaction in musicians (instrumentalists, vocalists) and compared them with age-matched non-musicians.</p></div><div><h3>Methods</h3><p>Eight six participants aged 20–40 y with normal hearing sensitivity were subjected to binaural tests using a standard group comparison research design. The participants were segregated into three groups – Group 1 included instrumentalists (n = 26, mean age: 17.73 ± 2.83 y), while Group 2 and Group 3 consisted of vocalists (n = 30, mean age: 19.30 ± 2.47 y) and non-musicians (n = 30, mean age: 18.20 ± 3.02 y) respectively. The binaural processes namely integration (Dichotic syllable test, DST; and virtual acoustic space identification - VASI) and interaction (Interaural difference thresholds for time and level: ITD &amp; ILD), were administered on all the participants.</p></div><div><h3>Results</h3><p>Statistical analyses showed the main effect of musicianship. Bonferroni pair-wise test revealed that the musicians (instrumentalists and vocalists) outperformed (<em>p</em> &lt; 0.05) non-musicians in all the tests. The differential advantage of the musical background was seen on the binaural integration test with instrumentalists performing better in the VASI test compared to vocalists, and vice-versa for DST. No difference was observed in interaction tasks (ITD &amp; ILD) between vocalists and instrumentalists (<em>p</em> &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>Musical background-induced differential advantages can be reasonably noted in the binaural skills of instrumentalists and vocalists (compared to non-musicians).</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45528039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing accuracy of cochlear measurements on magnetic resonance imaging and computed tomography: A step towards radiation-free cochlear implantation","authors":"Anurita Swarup ,&nbsp;Vinusree Karakkandy ,&nbsp;Preetam Chappity ,&nbsp;Suprava Naik ,&nbsp;Sanjay Kumar Behera ,&nbsp;Pradipta Kumar Parida ,&nbsp;Mohnish Grover ,&nbsp;Gaurav Gupta ,&nbsp;Prajna Paramita Giri ,&nbsp;Saurav Sarkar ,&nbsp;Pradeep Pradhan ,&nbsp;Dillip Kumar Samal ,&nbsp;Aswathi Kallyadan Veetil ,&nbsp;Asutosh Adhikari ,&nbsp;Saurav Nayak","doi":"10.1016/j.joto.2023.08.001","DOIUrl":"10.1016/j.joto.2023.08.001","url":null,"abstract":"<div><h3>Objective</h3><p>Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly employed in pre-operative evaluation for cochlear implant surgery. However, with a decrease in the age of implantation, even minor radiation exposure can cause detrimental effects on children over their lifetime. The current study compares different cochlear measurements from CT and MRI scans and evaluates the feasibility of using only an MRI scan for radiological evaluation before cochlear implantation.</p></div><div><h3>Methods</h3><p>A longitudinal observational study was conducted on 94 ears/47 children, employing CT and MRI scans. The CT and MRI scan measurements include, A value, B value, Cochlear duct length (CDL), two-turn cochlear length, alpha and beta angles to look for cochlear orientation. Cochlear nerve diameter was measured using MRI. The values were compared.</p></div><div><h3>Results</h3><p>The mean difference between measurements from CT and MRI scans for A value, B value, CDL, and two-turn cochlear length values was 0.567 ± 0.413 mm, 0.406 ± 0.368 mm, 2.365 ± 1.675 mm, and 2.063 ± 1.477 mm respectively without any significant difference. The alpha and beta angle measures were comparable, with no statistically significant difference.</p></div><div><h3>Conclusion</h3><p>The study suggests that MRI scans can be the only radiological investigation needed with no radiation risk and reduces the cost of cochlear implant program in the paediatric population. There is no significant difference between the measurements obtained from CT and MRI scans. However, observed discrepancies in cochlear measurements across different populations require regionally or race-specific standardized values to ensure accurate diagnosis and precision in cochlear implant surgery. This aspect must be addressed to ensure positive outcomes for patients.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44844536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute isolated vertigo with vertical up-beating nystagmus: A rare case of nucleus intercalatus of Staderini ischemia","authors":"Francesco Comacchio ,&nbsp;Giacomo Talenti ,&nbsp;Renzo Manara ,&nbsp;Chiara Briani","doi":"10.1016/j.joto.2023.09.001","DOIUrl":"https://doi.org/10.1016/j.joto.2023.09.001","url":null,"abstract":"<div><p>The role of intercalatus nucleus of Staderini (INS), the most caudal of the perihypoglossal nuclei, is much debated. Last research seems to suggest that this nucleus plays a role as a vertical eyes movements integrator. The few clinical reports present in the literature that describe isolated lesions of the INS have described patients presenting in acute with up-beating vertical spontaneous nystagmus. Isolated acute lesion of INS is, in fact, much rare, and, without other neurological signs, is exceptional. We present a case of acute isolated vertigo with no other neurological signs or symptoms, due to INS ischemia provoked by vertebral artery stenosis. The patient presented with spontaneous vertical up-beating nystagmus that showed at videonystagmographic recording, a clear exponential decay of angular slow-phase velocity, that is considered a typical sign of neural integrator impairment. This case seems to represent a further confirm that INS is part, as a vertical-to-position neural integrator, of the neural circuit controlling the vertical eyes movements.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49788826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}