TAJ: Journal of Teachers Association最新文献

{"title":"Role of Plastic Surgery in the Management of Diabetic Foot Ulcer","authors":"Most Afroza Nazneen, Mohammad Ali Choudhury","doi":"10.3329/taj.v36i1.68283","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68283","url":null,"abstract":"This article introduces plastic surgeons' various roles in managing diabetic foot ulcers. The role of plastic surgeons is multidimensional and, of course, challenging. Sometimes, the healing process of diabetic ulcer is as simple as only adequate wound care. Sometimes, the ulcer needs reconstruction through a skin graft or flap coverage. Unfortunately, some patients need amputation or disarticulation. Again, plastic surgeons are maximizing patients' future movement ability in the case of amputation. Thus, an experienced plastic surgeon can provide an optimum lifestyle to the diabetic patient. \u0000TAJ 2022; 36: No-1: 55-61","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127153443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors of Community-Acquired Pneumonia Among Under-Five Children in a Tertiary Level Hospital in Rajshahi","authors":"C. Ara, L. Sharmin, F. Begum, Sanchita Sarker, M. B. Hossain, S. Yeasmin, Md Sanaul Haque Mia","doi":"10.3329/taj.v36i1.68276","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68276","url":null,"abstract":"Introduction: Community-acquired pneumonia (CAP) top the list of causes of under-five children mortality worldwide. Therefore, properly assessing and controlling these risk factors may help decrease the morbidity and mortality in under-five children suffering from CAP in Bangladesh and thereby help improve the quality of life of our future generation. \u0000Objective: To assess the risk factors of CAP among under-five children ( 2-59 months ) in a tertiary-level hospital in Rajshahi. \u0000Materials and methods: This case-control study was carried out in the Department of Pediatrics and EPI Center of Rajshahi Medical College Hospital, RMCH, from January 2017 to December 2018 to determine the risk factors of CAP among children under five. For this study, 246 children aged two months to 59 months were selected by purposive sampling. One hundred twenty-three were cases that were taken indoors, and 123 were healthy controls taken from the outpatient department & EPI center. After taking written consent from guardians, history was taken, and a physical examination was done. All information was recorded in a predesigned data sheet. The chi-square test and odds ratio were used to demonstrate significance. \u0000Results: Among 246 children, more patients of both groups were male and came from rural areas. Cases were predominantly under 12 months and came from lower socioeconomic status. A statistically significant association was found between social class and CAP (<0.001); the father's literacy was inversely related to CAP (p-value <0.001). Types of housing, living room ventilation, overcrowding, fuel and cookers used for cooking, parental smoking, malnutrition, history of diarrhea and presence of anemia, prematurity, and low birth weight were significantly associated with CAP (p-value <0.05). \u0000Conclusion: Proper assessment of these risk factors and controlling them may help decrease the morbidity and mortality in under-five children suffering from CAP in Bangladesh and thereby help improve the quality of life of our future generation. \u0000TAJ 2022; 36: No-1: 23-31","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129949033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological Profile and Outcome of Pregnancy Associated Acute Kidney Injury","authors":"Md. Ruhul Amin, Al Mirajun Hoque, Marufa Hussain, Partho Moni Bhattacharyya, Md Amzad Hossain Sardar, Md Aminul Hasan, M. J. Alam","doi":"10.3329/taj.v36i1.68322","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68322","url":null,"abstract":"Background: In developing countries, pregnancy-associated acute kidney injury (PAAKI) is a significant cause of maternal and neonatal mortality and morbidity. A systematic evaluation is essential to understand its frequency and severity in our setting.  Objectives: Primary aim of our study was to evaluate the epidemiological profile and outcome of patients with pregnancy-associated acute kidney injury.  Patients and Methods: The study was conducted in the Department of Nephrology, Rajshahi medical college hospital, from January 2019 to March 2020. A total of 83 patients with pregnancy-associated acute kidney injury were evaluated. Patients who had a history of chronic kidney disease or were diagnosed as a case of chronic kidney disease were excluded from the study. \u0000Result: The mean age±SD was 25.39±5.90 years. The majority were <30 years of age (56.6%). Only 24.1% had completed regular antenatal checkups. Preeclamsic toxaemia was present in 10.8% of patients. 85.5% of delivery was performed at hospitals/ clinics, and 75.9% of delivery was done by cesarean section. Unskilled birth attendants did 9.7% of delivery. Anaemia was present in 41.0% of patients at presentation, and 67.5% received a blood transfusion. Maternal mortality was 32.5%, and neonatal mortality was 21.7%. Renal replacement therapy was given in 56 (67.5%) patients. Among them, 47 (83.9%) received hemodialysis. Common causes of pregnancy-associated acute kidney injury were found to be sepsis (77.1%), postpartum hemorrhage (41.0%), disseminated intravascular coagulation (21.7%), severe preeclampsia (16.9%), HELLP syndrome (2.4%) and transfusion reaction (7.2%). 31.4% of patients recovered completely, and 10.8% of patients developed chronic kidney disease. \u0000Conclusion: Providing good quality perinatal care is essential to reduce the frequency of pregnancy-associated acute kidney injury and maternal and neonatal mortality related to this. \u0000TAJ 2022; 36: No-1: 127-134","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114080496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Efficacy and Safety of Terbinafine Vs. Itraconazole in the Treatment of Tinea Pedis","authors":"M. Kabir, Md Abdul Latif Khan, Md. Shirajul Islam Khan, A. Karim, Md. Mustafizur Rahman, A. Jamil","doi":"10.3329/taj.v36i1.68302","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68302","url":null,"abstract":"Background: Tinea pedis is a dermatophytosis of the feet usually occurs between the toes with the webspace between the fourth and fifth digits but, in many cases, may appear as an extensive pattern on the bottom and sides of the feet. Terbinafine and itraconazole were evaluated with the efficacy/effectiveness and toxicity in the systemic treatment of Tinea pedis and compared with each other.  Objective: To compare the efficacy and safety of terbinafine vs. itraconazole in treating tinea pedis. \u0000Materials and Methods: A total of 50 patients were selected, and they were divided into groups (group-A and group B), each of which included 25 patients. Group A was given oral Terbinafine 250 mg daily for two weeks. Group B was given oral Itraconazole 200mg daily for the same duration. Patients were observed for the efficacy and side effects of the trial medicines. A baseline complete blood picture, liver and renal function test, and urine analysis were done and repeated frequently during therapy. \u0000Results: Most patients were in the fourth decade in both groups, and the male-to-female ratio was almost 4:1. Two groups of people were studied: group-A with terbinafine 250 mg daily and group B with itraconazole 200 mg daily for 14 days. Evaluated weekly during treatment and 02 weeks after cessation of therapy, and finally on 08th week to see the clinical improvement and adverse effects. The clinical response was found in chronic hyperkeratotic type: 08/08, 08/08; chronic interdigital type: 07/07, 07/06; vesico-bullous type: 06/05, 06/05; Mixed type: 04/03, 03/02 in group-A and group-B respectively. On average, 92% clinical improvement was found in group-A and 84% in group B. Most patients had nausea (20.0%) followed by 08% diarrhea in group A. On the other hand, in group B, most patients had nausea (28.0%), followed by 4.0% fatigue and 4.0% diarrhea, and only 01 patient found elevated liver enzyme but did not exceed the upper limit. 80% of patients in the terbinafine group had transient, mild to moderate nausea. \u0000Conclusion: No significant differences in efficacy and toxicity were found between terbinafine and itraconazole groups. Terbinafine may represent a good alternative for treating Tinea Pedis in patients who cannot take itraconazole or other available drugs due to contraindications. \u0000TAJ 2022; 36: No-1: 75-82","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124162074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-Prevalence Survey for the Hospital-Acquired Infections and Infection Prevention and Control Status of Different Wards of Rajshahi Medical College Hospital","authors":"Md. Jawadul Haque, F. Yasmin, Md Ashfaq Arif, N. Rahman, Rehana Parven, M. Asaduzzaman, Muhammad Zubayer Alam","doi":"10.3329/taj.v36i1.68274","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68274","url":null,"abstract":"Introduction: Healthcare-associated infections represent significant obstacles to providing high-quality healthcare and have been directly linked to ineffective infection control procedures. There is currently a shortage of trustworthy data in Bangladesh describing the epidemiology of hospital-acquired infections (HAIs), which is necessary for the development of effective infection prevention and control measures. This study's goal was to assess the frequency, nature, and risk factors of HAIs in acute care hospitals in Northern Bangladesh. \u0000Methods: This was a pilot point prevalent survey conducted in the medicine, surgery, gynecology, and obstetrics departments of Rajshahi Medical College Hospital between August 2022 to September 2022. Data were collected by two questionnaires for disease profile and hospital-acquired infection. In addition, a checklist was used for the observation of the infection prevention and control (IPC) status of different wards. \u0000Result: Approximately 900 patients' data were collected during this time period. The overall prevalence of HAI was found to be 3.7%. The prevalence of HAI, especially surgical site Infection (SSI), in the obstetrics ward, was 4.2%, and the Medicine ward was 3.9%, respectively. The prevalence of hospital-acquired infection in the surgery ward is 7.7%. Approximately 41.7% of patients developed SSI on the 6th post operative day (POD). The Infection prevention and control status of different wards was similar, which was not satisfactory. \u0000Conclusion: This surveillance might help concerned authorities and policymakers by making some crucial steps to monitor and reduce hospital-acquired infections and HAIs in hospitals. \u0000TAJ 2022; 36: No-1: 9-15","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125731345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Cholinesterase Level in Patients with Cirrhosis of Liver and Its Correlation with the Severity of the Disease","authors":"M. Rashid, Md Shafiqul Islam, M. Parvin, A. Saifullah, B. C. Shil, Md. Habibur Rahman, Mst Musarrat Sultana","doi":"10.3329/taj.v36i1.68279","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68279","url":null,"abstract":"Background: Serum cholinesterase mainly comes from the liver, a sensitive indicator of the synthetic capacity of the liver. It can be used as a prognostic marker for cirrhosis. \u0000Objectives: To measure the serum cholinesterase level in cirrhotic patients and to correlate its level with the severity of the disease as per the Child-Pugh score. \u0000Methodology: This cross-sectional study was conducted in the Department of Gastroenterology, Sir Salimullah Medical College Mitford Hospital, Dhaka, Bangladesh, from January 2018 to December 2018. Fifty adult patients with cirrhosis of the liver were enrolled. Fifty healthy individuals were also taken to compare serum cholinesterase levels. Cirrhotic patients were grouped strictly into A, B, and C classes, as per the Child-Pugh score. Serum cholinesterase level was measured in all participants. The correlation between cholinesterase level and the severity of the disease was analyzed. \u0000Result: Mean age of the patients was 47.42 ± 12.40 years and 47.22 ± 11.99 years in cirrhotic patients and healthy group, respectively. The number of patients in the Child-Pugh A, B, and C subgroups was 12 (24%), 20 (40%), and 18 (36%), respectively. The mean serum cholinesterase level was 2938 ± 1561 U/L in cirrhotic patients and 9036 ± 2024 U/L in the healthy group. Serum cholinesterase level in different Child-Pugh class was 4740 ± 1046 U/l (Child A), 3157 ± 1161 U/l (Child B), and 1493 ± 500 U/l (Child C). Serum Cholinesterase was positively correlated with serum albumin and negatively correlated with bilirubin, prothrombin time, and INR. A negative correlation was found between serum Cholinesterase level and the severity of the disease. \u0000Conclusion: Serum cholinesterase level was low in cirrhotic patients, and its level was inversely correlated with the severity of the disease. Thus it can be used as a prognostic marker of cirrhosis. However, further study with a large sample size could explain this more precisely. \u0000TAJ 2022; 36: No-1: 33-40","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124339765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Dermatophytic Infections and Their Antifungal Susceptibility Pattern in the Rajshahi Region","authors":"Md Mottalib Hossain Khan, Md. Ahsanul Haque, F. Kabir, S. Nath, Rozina Aktar Zahan, N. Rahman","doi":"10.3329/taj.v36i1.68317","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68317","url":null,"abstract":"Background: Dermatophytes are the most significant fungi because of their widespread involvement in the population and their prevalence worldwide. Bangladesh's hot and humid climate, overcrowded population, poverty, malnutrition, and ignorance make dermatophytosis a common cutaneous infection. These infections occur in both healthy and immunocompromised patients. Dermatophytes are responsible for most cutaneous fungal infections, and the estimated lifetime risk of acquiring a dermatophyte infection is 10-20%. \u0000Objective: To isolate and identify different dermatophytes and their antifungal susceptibility pattern in the Rajshahi region.  Materials and Methods: Different clinical samples (e.g., skin scrapings, nail clipping, and hair plucking) were collected under aseptic precautions. The isolation and identification of dermatophytes were performed through a microscopic examination using 10% KOH mount, mycological culture, and species identification by lactophenol cotton blue mount from positive culture. In addition, all dermatophytes isolates were subjected to antifungal susceptibility testing using the agar-based disk diffusion method in Mueller Hinton agar media. \u0000Results: Out of 171 samples, Trichophyton rubrum was the predominant dermatophyte species with 76(71.7%), followed by T.mentagrophyte were 15(14.2%), E. floccosum were 12(11.3%), and M. canis were 03(2.8%). voriconazole, clotrimazole, and itraconazole were more effective drugs. Griseofulvin was the least effective drug, followed by fluconazole. \u0000Conclusion: This study indicates dermatophytosis is a common skin disease in northern Bangladesh. Due to the increasing trend of antifungal drug resistance among dermatophytes, treatment should be based on antifungal sensitivity testing. \u0000TAJ 2022; 36: No-1: 119-125","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129043956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT Measurement of Maxillary Sinus Volume Among the Population of Rajshahi District in Bangladesh","authors":"Sadia Afrin, Dhm Fazle Rabbi, Rashed Mustafa, W. Ahmed, Akhtari Afroze","doi":"10.3329/taj.v36i1.68303","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68303","url":null,"abstract":"Background: The volumetric measurement of the maxillary sinuses is essential in assessing the incidence of sinusitis and cancer and measuring the intimate relationship between teeth and maxillary sinuses. There have been reports in multiple studies that there is racial variation concerning age and gender. This study aims to determine whether the sinus volume of males and females differ and its relation to age. \u0000Methods: This descriptive observational study was carried out among 100 respondents between the age of 11- 60 years who were residing in Rajshahi during the study period of one year, i.e., January 2018 to December 2018. The data has been collected from the Department of Radiology and Imaging of Rajshahi Medical College Hospital (RMCH) from the patients who had undergone CT scan examinations. The measurements were directly taken from a computer provided with an electronic caliper. After that, the sinus volume was calculated manually using the following formula (height x width x depth x 0.5). The quality of the data was obtained diligently, and ethical issues were properly maintained in all the steps of this study. \u0000Results: There were 50 males and 50 females, ranging from 11 – 60 years of age, where the mean (± SD) age was 36.7 (± 14.8) years. The mean (± SD) volume of the maxillary sinus in the male group was 17 (± 4.6) cm3 for the right side and 17.5 (± 4.7) cm3 for the left side, which was significantly more than the female group, 14.7 (± 3.7) cm3 for the right side and 15.1 (± 3.7) cm3 for the left side (p = 0.031). Concerning age, the distribution of maxillary sinus volume showed the highest values between 21-30 years of age, and then it decreased both on the right and left side; this finding was found to be statistically significant (p = 0 .018). \u0000Conclusion: This study provides salient information regarding maxillary sinus volume among the people of the Rajshahi district of Bangladesh. This study's results will help establish a reference dataset regarding anatomical measurements of the maxillary sinus. \u0000TAJ 2022; 36: No-1: 83-87","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123764986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Empagliflozin as Add-on Therapy in Patients with Uncontrolled Type 2 Diabetes Mellitus","authors":"Mita Rani Joysoual, Shahin Ara, Md. Nazmul Haque, R. Ghosh, T. Afroze, Saqib Salah Aufi","doi":"10.3329/taj.v36i1.68304","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68304","url":null,"abstract":"Background: Metformin is recommended as first-line pharmacotherapy for patients with type 2 Diabetes Mellitus (T2DM) who fail to achieve glycemic control through lifestyle modification. Metformin initially lowers blood glucose, but as diabetes progresses, it alone frequently fails to maintain glycemic control, and additional therapies are required. Empagliflozin is a potent and selective sodium-glucose co-transporter 2 (SGLT2) inhibitor that is effective in reducing blood sugar levels as monotherapy or add-on to existing therapy with significant improvements in glycemic control and weight. \u0000Materials & Methods: This quasi-experimental study was conducted in the Department of Pharmacology and Therapeutics in collaboration with Rajshahi Diabetic Association General Hospital, Rajshahi, for one year from January 2021 to December 2021 on 50 uncontrolled T2DM patients (glycosylated hemoglobin, HbA1c > 7.0 to ≤ 10.5%) for more than 12 weeks. The investigating drug, empagliflozin 10 mg (1 tablet) as a once-daily dose, was added to the ongoing treatment of each patient as 3rd line treatment and was followed up at 6 and 12 weeks. \u0000Results: The mean FBS at baseline was 10.8 mmol/L, which declined to 8.5 mmol/L at six weeks and then to 7.2 mmol/L after 12 weeks of intervention with Empagliflozin as add-on therapy in patients with uncontrolled T2DM. The overall reduction of FBS from baseline to 12 weeks of intervention was statistically significant (p < 0.001). Simultaneously the mean HbA1c also reduced from 9.4% to 7.7% after six weeks and to 7.1% after 12 weeks of intervention (p < 0.001). The mean systolic and diastolic blood pressures decreased from 129 mmHg to below 120 mmHg (p < 0.001) and 82.3 mmHg to below 80 mmHg (p = 0.029), respectively, after three months of intervention. \u0000Conclusion: Empagliflozin as add-on therapy responded well in patients with uncontrolled T2DM (previously treated with metformin combined with either sulfonylurea or DPP-4 inhibitors and/or supplemented by insulin) in achieving glycemic control.  \u0000TAJ 2022; 36: No-1: 89-95","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132346797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Effect of Conventional Medical Management and Ivabradine with Conventional Medical Management on Quality of Life in Patients with Chronic Heart Failure","authors":"R. Ghosh, Rajeshwari Ghose, Md Rezaul Karim, Shahin Ara, Md Azizul Haque, Md. Nazmul Haque, Mita Rani Joysoual","doi":"10.3329/taj.v36i1.68273","DOIUrl":"https://doi.org/10.3329/taj.v36i1.68273","url":null,"abstract":"Background: The study aimed to see the effectiveness and role of ivabradine on the quality of life in chronic heart failure suffering patients. This open-label Randomized controlled Trial was conducted to assess the effect of ivabradine plus conventional medical management over conventional medical management on quality-of-life parameters among 100 patients of chronic heart failure from January 2021 to December 2021 in the Department of Pharmacology & Therapeutics in collaboration with the Department of Cardiology & Medicine, Rajshahi Medical College Hospital, Rajshahi. \u0000Materials and methods: According to the drug allocation study population was divided into a control group (50 patients) and an experimental group (50 patients). Minnesota Living with Heart Failure questionnaire (MLWHFQ) was used to assess the quality of life, and the resting heart rate was measured by 12-lead electrocardiography. Baseline demographic and clinical characteristics were recorded, and patients were followed up at four weeks and 12 weeks of treatment. \u0000Results: The comparison of mean differences of MLWHFQ score at first and second follow-up visits between the two study groups was statistically significant [t (100) = 2.43 p < 0.05 & t (100) = 6.60 p < 0.001 respectively]. According to the MLWHFQ cut-point score, it was also observed that poor baseline quality of life gradually shifted to good quality after four weeks and 12 weeks of treatment, and it was proportionately higher in the experimental group. Relations between the respondents of both study groups and their different qualities of life during the first follow-up visit (x2 = 13.69, df = 2, p < 0.05) and second follow-up visit (x2 = 22.79, df = 2, p < 0.001) were statistically significant.The comparison of the mean (±SD) heart rate between the two study groups was statistically significant (p <0.001) only during the second follow-up visit. \u0000Conclusion: This study concluded that adding ivabradine to conventional medical management in treating patients with chronic heart failure improves their symptoms, quality of life, and heart rate and ultimately reduces the morbidity and mortality of such patients. \u0000TAJ 2022; 36: No-1: 1-8","PeriodicalId":373921,"journal":{"name":"TAJ: Journal of Teachers Association","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115387020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}