Informatics最新文献

{"title":"Technology independent optimization when implementing sparse systems of disjunctive normal forms of Boolean functions in ASIC","authors":"P. Bibilo, S. Kardash","doi":"10.37661/1816-0301-2024-21-1-28-47","DOIUrl":"https://doi.org/10.37661/1816-0301-2024-21-1-28-47","url":null,"abstract":"Objectives. The problem of choosing the best methods and programs for circuit implementation as part of digital ASIC (Application-Specific Integrated Circuit) sparse systems of disjunctive normal forms (DNF) of completely defined Boolean functions is considered. For matrix forms of sparse DNF systems, the ternary matrix specifying elementary conjunctions contains a large proportion of undefined values corresponding to missing literals of Boolean input variables, and the Boolean matrix specifying the occurrences of conjunctions in DNF functions contains a large proportion of zero values.Methods. It is proposed to investigate various methods of technologically independent logical optimization performed at the first stage of logical synthesis: joint minimization of systems of functions in the DNF class, separate and joint minimization in classes of multilevel representations in the form of Boolean networks and BDD representations using mutually inverse cofactors, as well as the division of a system of functions into subsystems with a limited number of input variables and the method of block cover of DNF systems, focused on minimizing the total area of the blocks forming the cover.Results. When implementing sparse DNF systems of Boolean functions in ASIC, along with traditional methods of joint minimization of systems of functions in the DNF class, methods for optimizing multilevel representations of Boolean function systems based on Shannon expansions can be used for technologically independent optimization, while separate minimization and joint minimization of the entire system as a whole turn out to be less effective compared with block partitions and coatings of the DNF system and subsequent minimization of multilevel representations. Schemes obtained as a result of synthesis using minimized representations of Boolean networks often have a smaller area than schemes obtained using minimized BDD representations.Conclusion. For the design of digital ASIC, the effectiveness of combined approach is shown, when initially the block coverage programs of the DNF system is used, followed by the use of programs to minimize multilevel block representations in the form of Boolean networks minimized based on Shannon expansion.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140365709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computational Ensemble Gene Co-Expression Networks for the Analysis of Cancer Biomarkers","authors":"Julia Figueroa-Martínez, Dulcenombre M. Saz-Navarro, Aurelio López-Fernández, Domingo S. Rodríguez-Baena, Francisco A. Gómez-Vela","doi":"10.3390/informatics11020014","DOIUrl":"https://doi.org/10.3390/informatics11020014","url":null,"abstract":"Gene networks have become a powerful tool for the comprehensive examination of gene expression patterns. Thanks to these networks generated by means of inference algorithms, it is possible to study different biological processes and even identify new biomarkers for such diseases. These biomarkers are essential for the discovery of new treatments for genetic diseases such as cancer. In this work, we introduce an algorithm for genetic network inference based on an ensemble method that improves the robustness of the results by combining two main steps: first, the evaluation of the relationship between pairs of genes using three different co-expression measures, and, subsequently, a voting strategy. The utility of this approach was demonstrated by applying it to a human dataset encompassing breast and prostate cancer-associated stromal cells. Two gene networks were computed using microarray data, one for breast cancer and one for prostate cancer. The results obtained revealed, on the one hand, distinct stromal cell behaviors in breast and prostate cancer and, on the other hand, a list of potential biomarkers for both diseases. In the case of breast tumor, ST6GAL2, RIPOR3, COL5A1, and DEPDC7 were found, and in the case of prostate tumor, the genes were GATA6-AS1, ARFGEF3, PRR15L, and APBA2. These results demonstrate the usefulness of the ensemble method in the field of biomarker discovery.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Research Interest in ChatGPT and Other Natural Language Processing Tools from a Public Health Perspective: A Bibliometric Analysis","authors":"G. Favara, M. Barchitta, A. Maugeri, R. Magnano San Lio, A. Agodi","doi":"10.3390/informatics11020013","DOIUrl":"https://doi.org/10.3390/informatics11020013","url":null,"abstract":"Natural language processing, such as ChatGPT, demonstrates growing potential across numerous research scenarios, also raising interest in its applications in public health and epidemiology. Here, we applied a bibliometric analysis for a systematic assessment of the current literature related to the applications of ChatGPT in epidemiology and public health. Methods: A bibliometric analysis was conducted on the Biblioshiny web-app, by collecting original articles indexed in the Scopus database between 2010 and 2023. Results: On a total of 3431 original medical articles, “Article” and “Conference paper”, mostly constituting the total of retrieved documents, highlighting that the term “ChatGPT” becomes an interesting topic from 2023. The annual publications escalated from 39 in 2010 to 719 in 2023, with an average annual growth rate of 25.1%. In terms of country production over time, the USA led with the highest overall production from 2010 to 2023. Concerning citations, the most frequently cited countries were the USA, UK, and China. Interestingly, Harvard Medical School emerges as the leading contributor, accounting for 18% of all articles among the top ten affiliations. Conclusions: Our study provides an overall examination of the existing research interest in ChatGPT’s applications for public health by outlining pivotal themes and uncovering emerging trends.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes and Mitigation Practices of Requirement Volatility in Agile Software Development","authors":"Abdul-Ameer S. Mohammad, Job Mathew Kollamana","doi":"10.3390/informatics11010012","DOIUrl":"https://doi.org/10.3390/informatics11010012","url":null,"abstract":"One of the main obstacles in software development projects is requirement volatility (RV), which is defined as uncertainty or changes in software requirements during the development process. Therefore, this research tries to understand the underlying factors behind the RV and the best practices to reduce it. The methodology used for this research is based upon qualitative research using interviews with 12 participants with experience in agile software development projects. The participants hailed from Austria, Nigeria, the USA, the Philippines, Armenia, Sri Lanka, Germany, Egypt, Canada, and Turkey and held roles such as project managers, software developers, Scrum Masters, testers, business analysts, and product owners. Our findings based on our empirical data revealed six primary factors that cause RV and three main agile practices that help to mitigate it. Theoretically, this study contributes to the body of knowledge relating to RV management. Practically, this research is expected to aid software development teams in comprehending the reasons behind RV and the best practices to effectively minimize it.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Multidimensional Embeddings for Decision Support Using Advanced Visualization Techniques","authors":"O. Kurasova, Arnoldas Budžys, V. Medvedev","doi":"10.3390/informatics11010011","DOIUrl":"https://doi.org/10.3390/informatics11010011","url":null,"abstract":"As artificial intelligence has evolved, deep learning models have become important in extracting and interpreting complex patterns from raw multidimensional data. These models produce multidimensional embeddings that, while containing a lot of information, are often not directly understandable. Dimensionality reduction techniques play an important role in transforming multidimensional data into interpretable formats for decision support systems. To address this problem, the paper presents an analysis of dimensionality reduction and visualization techniques that embrace complex data representations and are useful inferences for decision systems. A novel framework is proposed, utilizing a Siamese neural network with a triplet loss function to analyze multidimensional data encoded into images, thus transforming these data into multidimensional embeddings. This approach uses dimensionality reduction techniques to transform these embeddings into a lower-dimensional space. This transformation not only improves interpretability but also maintains the integrity of the complex data structures. The efficacy of this approach is demonstrated using a keystroke dynamics dataset. The results support the integration of these visualization techniques into decision support systems. The visualization process not only simplifies the complexity of the data, but also reveals deep patterns and relationships hidden in the embeddings. Thus, a comprehensive framework for visualizing and interpreting complex keystroke dynamics is described, making a significant contribution to the field of user authentication.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling Insights: A Bibliometric Analysis of Artificial Intelligence in Teaching","authors":"Malinka Ivanova, G. Grosseck, Carmen Holotescu","doi":"10.3390/informatics11010010","DOIUrl":"https://doi.org/10.3390/informatics11010010","url":null,"abstract":"The penetration of intelligent applications in education is rapidly increasing, posing a number of questions of a different nature to the educational community. This paper is coming to analyze and outline the influence of artificial intelligence (AI) on teaching practice which is an essential problem considering its growing utilization and pervasion on a global scale. A bibliometric approach is applied to outdraw the “big picture” considering gathered bibliographic data from scientific databases Scopus and Web of Science. Data on relevant publications matching the query “artificial intelligence and teaching” over the past 5 years have been researched and processed through Biblioshiny in R environment in order to establish a descriptive structure of the scientific production, to determine the impact of scientific publications, to trace collaboration patterns and to identify key research areas and emerging trends. The results point out the growth in scientific production lately that is an indicator of increased interest in the investigated topic by researchers who mainly work in collaborative teams as some of them are from different countries and institutions. The identified key research areas include techniques used in educational applications, such as artificial intelligence, machine learning, and deep learning. Additionally, there is a focus on applicable technologies like ChatGPT, learning analytics, and virtual reality. The research also explores the context of application for these techniques and technologies in various educational settings, including teaching, higher education, active learning, e-learning, and online learning. Based on our findings, the trending research topics can be encapsulated by terms such as ChatGPT, chatbots, AI, generative AI, machine learning, emotion recognition, large language models, convolutional neural networks, and decision theory. These findings offer valuable insights into the current landscape of research interests in the field.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140432804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genealogical Data-Driven Visits of Historical Cemeteries","authors":"A. L. Duca, Matteo Abrate, Andrea Marchetti, Manuela Moretti","doi":"10.3390/informatics11010009","DOIUrl":"https://doi.org/10.3390/informatics11010009","url":null,"abstract":"This paper describes the Integration of Archives and Cultural Places (IaCuP) project, which aims to integrate information about a historical cemetery, including its map and grave inventory, with genealogical and documentary knowledge extracted from relevant historical archives. The integrated data are accessible to cemetery visitors through an interactive mobile application, enabling them to navigate a graphical representation of the cemetery while exploring comprehensive visualizations of genealogical data. The basic idea stems from the desire to provide people with access to the rich context of cultural sites, which have often lost their original references over the centuries, making it challenging for individuals today to interpret the meanings embedded within them. The proposed approach leverages large language models (LLMs) to extract information from relevant documents and Web technologies to represent such information as interactive visualizations. As a practical case study, this paper focuses on the Jewish Cemetery in Pisa and the Historical Archives of the Jewish Community in Pisa, working on the genealogical tree of one of the most representative families resting in the cemetery.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140441589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topic Extraction: BERTopic's Insight into the 117th Congress's Twitterverse","authors":"Margarida Mendonça, Álvaro Figueira","doi":"10.3390/informatics11010008","DOIUrl":"https://doi.org/10.3390/informatics11010008","url":null,"abstract":"As social media (SM) becomes increasingly prevalent, its impact on society is expected to grow accordingly. While SM has brought positive transformations, it has also amplified pre-existing issues such as misinformation, echo chambers, manipulation, and propaganda. A thorough comprehension of this impact, aided by state-of-the-art analytical tools and by an awareness of societal biases and complexities, enables us to anticipate and mitigate the potential negative effects. One such tool is BERTopic, a novel deep-learning algorithm developed for Topic Mining, which has been shown to offer significant advantages over traditional methods like Latent Dirichlet Allocation (LDA), particularly in terms of its high modularity, which allows for extensive personalization at each stage of the topic modeling process. In this study, we hypothesize that BERTopic, when optimized for Twitter data, can provide a more coherent and stable topic modeling. We began by conducting a review of the literature on topic-mining approaches for short-text data. Using this knowledge, we explored the potential for optimizing BERTopic and analyzed its effectiveness. Our focus was on Twitter data spanning the two years of the 117th US Congress. We evaluated BERTopic’s performance using coherence, perplexity, diversity, and stability scores, finding significant improvements over traditional methods and the default parameters for this tool. We discovered that improvements are possible in BERTopic’s coherence and stability. We also identified the major topics of this Congress, which include abortion, student debt, and Judge Ketanji Brown Jackson. Additionally, we describe a simple application we developed for a better visualization of Congress topics.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140453199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Relation between Contextual Social Determinants of Health and COVID-19 Occurrence and Hospitalization","authors":"Aokun Chen, Yunpeng Zhao, Yi Zheng, Hui Hu, Xia Hu, Jennifer N. Fishe, W. Hogan, Elizabeth A Shenkman, Yi Guo, Jiang Bian","doi":"10.3390/informatics11010004","DOIUrl":"https://doi.org/10.3390/informatics11010004","url":null,"abstract":"It is prudent to take a unified approach to exploring how contextual social determinants of health (SDoH) relate to COVID-19 occurrence and outcomes. Poor geographically represented data and a small number of contextual SDoH examined in most previous research studies have left a knowledge gap in the relationships between contextual SDoH and COVID-19 outcomes. In this study, we linked 199 contextual SDoH factors covering 11 domains of social and built environments with electronic health records (EHRs) from a large clinical research network (CRN) in the National Patient-Centered Clinical Research Network (PCORnet) to explore the relation between contextual SDoH and COVID-19 occurrence and hospitalization. We identified 15,890 COVID-19 patients and 63,560 matched non-COVID-19 patients in Florida between January 2020 and May 2021. We adopted a two-phase multiple linear regression approach modified from that in the exposome-wide association (ExWAS) study. After removing the highly correlated SDoH variables, 86 contextual SDoH variables were included in the data analysis. Adjusting for race, ethnicity, and comorbidities, we found six contextual SDoH variables (i.e., hospital available beds and utilization, percent of vacant property, number of golf courses, and percent of minority) related to the occurrence of COVID-19, and three variables (i.e., farmers market, low access, and religion) related to the hospitalization of COVID-19. To our best knowledge, this is the first study to explore the relationship between contextual SDoH and COVID-19 occurrence and hospitalization using EHRs in a major PCORnet CRN. As an exploratory study, the causal effect of SDoH on COVID-19 outcomes will be evaluated in future studies.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139529690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simulation of discrete control systems with parallelism of behavior","authors":"D. Cheremisinov, L. Cheremisinova","doi":"10.37661/1816-0301-2023-20-4-24-37","DOIUrl":"https://doi.org/10.37661/1816-0301-2023-20-4-24-37","url":null,"abstract":"Objectives. The problem of functional verification of control devices with respect to their design specification is considered. When solving the problems of implementing and testing of discrete systems, one has to deal with the presence of parallelism in the behavior of interacting control objects, which is also displayed in the assignment for designing control systems. The aim of the work is to develop a method for simulating descriptions of such systems, which allows their behavior testing dynamically on the area limited by their possible functioning.Methods. The paper considers a class of control systems with parallelism of the processes occurring in them, which permits linearization of their execution. To specify the behavior of such control systems, it is proposed to use the PRALU language of parallel control algorithms, which is based on Petri nets and which allows to order events occurring during the device operation. An object-oriented approach to simulation of the description of the control algorithm at the transaction level is proposed. For this purpose, a TLM (Transaction-Level Modeling) model has been developed for describing the devices with behavior parallelism in PRALU language. The transaction level model describes a system as a set of interacting processes that run in parallel and determine the behavior of the system over time.Results. The key concepts of the TLM model for simulating the descriptions of control algorithms in the PRALU language are defined: data structure, transactions, processes, and a barrier mechanism for synchronization of parallel processes. A method is proposed for transforming the description of an algorithm in the language into a TLM model, which is based on the representation of language operations as compositions of elementary operations that are performed sequentially. The set of these operations forms the basis for the algorithmic decomposition of a parallel algorithm in PRALU language into intermediate language program that is executed strictly sequentially. Translators of this program into the Verilog and C languages have been developed, the results of their compilation are simulators of the behavior of control system.Conclusion. The proposed simulation method can be used to create a test bench for functional verification of the circuit implementation of control devices with behavior parallelism. In this case, test sequences for verifying the circuit implementation can be generated dynamically – in the process of simulating the description of the algorithm in the PRALU language directly the control device or system, which include the control algorithm and the algorithms of controlled objects behavior.","PeriodicalId":37100,"journal":{"name":"Informatics","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139143437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}