Dentistry 3000Pub Date : 2019-07-25DOI: 10.5195/D3000.2019.90
Fernanda Mafei Felix da Silva, Christiane Vasconcelos Cruz, Luíse Leal, M. de Castro Costa
{"title":"Aesthetic Perception and psychological impact of molar-incisor hypomineralisation among patients and parents","authors":"Fernanda Mafei Felix da Silva, Christiane Vasconcelos Cruz, Luíse Leal, M. de Castro Costa","doi":"10.5195/D3000.2019.90","DOIUrl":"https://doi.org/10.5195/D3000.2019.90","url":null,"abstract":"Abstract The aim of this study was investigate`s patient and parent’s aesthetic perception and psychological impact of molar-incisor hypomineralisation (MIH) and to assess the correlation of MIH with caries experience. The sample comprised 56 children, 28 with MIH and 28 without MIH (comparison group), and their gardens (n=56). For the perception data we used the Child and Parent’s Questionnaire of Teeth Appearance. We used the European Academic of Paediatric Dentistry (EAPD) criteria to define MIH. Caries experience was assessed by Decayed, Missing and Filled Teeth (DMFT) index. Chi-square, Student’s t-test and correlation tests were used with significance level set at 5%. Most children were male (n=35; 62.5%) and patients with MIH perceived their affected teeth as stainned (p=0.01). MIH was considered by parents (6.96±1.7) to enhance psychosocial condition (social, physical, and psychological social) of their children (p<0.01). Patients with severe MIH showed the worst perception about the color of the teeth (p=0.07). There was no correlation between DMFT scores and presence of MIH (p=0.80). Patients and parents perceived MIH. Groups with severe MIH (children/ parents) showed the worse aesthetic perception.","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41964319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-07-25DOI: 10.5195/D3000.2019.91
C. A. Fernandez, F. F. C. F. Ferreira, Christiane Vasconcellos Cruz, M. C. Costa
{"title":"Evaluation of Salivary and Oral Cell Collection Methods for Genomic DNA Extraction","authors":"C. A. Fernandez, F. F. C. F. Ferreira, Christiane Vasconcellos Cruz, M. C. Costa","doi":"10.5195/D3000.2019.91","DOIUrl":"https://doi.org/10.5195/D3000.2019.91","url":null,"abstract":"The use of saliva and oral cells as sources of biological material has gained attention, due to advantages such as facility, non-invasiveness, and great patient acceptance. The objective of the study was to compare four different types of saliva and oral buccal cell collecting methods for genomic DNA extraction: (1)Expectoration of saliva, (2)Expectoration of saliva with lingual stimulation, (3)Scraping with cytological brush, and (4)Scraping with cytological brush and expectoration of saliva. The sample was composed of students and employees from the Dental School of the Federal University of Rio de Janeiro (n = 20, 10 men and 10 women with mean age of 47.60 ± 15.70 and 20.50 ± 2.1, respectively). The collections were performed with an interval of at least one day between them and the participants were instructed to stay for less than 30 minutes without eating food and brushing teeth. Samples were stored at -20°C until DNA extraction was performed using a commercially available kit (Qiagen®). Differences in DNA yield between methods were test for statistical significance with an alpha of 0.05. No sexual dimorphism was observed in relation to the concentration of DNA (p=0.76), age (p=0.91), and ethnicities (p=0.72). There was no significant difference between the collection methods in relation to the quantity and purity of the extracted DNA (p≥0.05). All methods gave lower DNA yields than the ones obtained from blood or saliva collected through comercial kits and maybe carefully use forclinical diagnostic purposes or for research experiements requiring higher DNA concentrations.","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47510053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-07-25DOI: 10.5195/D3000.2019.88
C. A. D. Fonseca, D. Martelli, Ianná Luana Freitas Almeida, Galeno Hassen Sales, R. Andrade, V. Dias, L. M. Barros, H. Júnior
{"title":"Absence of history of oral cleft in first-degree relatives of patients with prostate cancer","authors":"C. A. D. Fonseca, D. Martelli, Ianná Luana Freitas Almeida, Galeno Hassen Sales, R. Andrade, V. Dias, L. M. Barros, H. Júnior","doi":"10.5195/D3000.2019.88","DOIUrl":"https://doi.org/10.5195/D3000.2019.88","url":null,"abstract":"Objective: To evaluate the occurrence of nonsyndromic cleft lip and/or palate (NSCL/P) in families of patients with prostate cancer (PC).Study design: We conducted a case-control study involving a total of 748 individuals, 280 of which had PC, and 468 were free-cancer healthy individuals. The patients answered a questionnaire with basic demographic information and family history of NSCL/P in first-degree relatives. The information collected was stored in a database and analyzed by using the statistical program SPSS® 24.0 for Windows (Chicago, IL, USA). In order to determine the association with NSCL/P, chi-square and Fisher’s exact test and odds ratio (OR) with its 95% confidence interval (95% CI) for risk magnitude assessment. Values with p<0.05 were considered statistically significant.Results: Of total patients with PC, 2 had a positive history of NSCL/P. In the control group, 7 patients reported family history of NSCL/P (1df chi-square, p=0.34; Fisher´s exact test, p=0.49). The average age of the cases diagnosed with PC was 71.35±7.70 years, and control group was 64.42±9.67 years.Conclusion: Despite the limited population, the frequency of NSCL/P was not significantly increased in the first-degree relatives of patients with PC. Studies with larger samples and molecular analyses are needed to better understand the possible relationships in the etiology of cancer and NSCL/P.","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48079381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-06-26DOI: 10.5195/D3000.2019.84
M. Omori, M. N. Matsumoto, R. A. Segato, L. Silva, P. N. Filho, E. Küchler
{"title":"The effect of estrogen on craniofacial dimensions: a systematic review","authors":"M. Omori, M. N. Matsumoto, R. A. Segato, L. Silva, P. N. Filho, E. Küchler","doi":"10.5195/D3000.2019.84","DOIUrl":"https://doi.org/10.5195/D3000.2019.84","url":null,"abstract":"Sex hormones have an effect on bone metabolism. However, it remains unclear how estrogen hormone affects mandible and maxilla growth and development. The aim of this study was to perform a systematic review to evaluate if estrogen is associated with developmental alterations in the maxilla/mandible phenotype. Material and methods: A computer search of the literature was performed using: Pubmed Medline (1966 – August 2018), Google Scholar and manual searching. A combination of the terms ‘estrogens', ‘mandible’, ‘dental arch’, ‘maxilla’, ‘craniofacial’, ‘growth’ and ‘development’ was used. Studies that used animal models to evaluate the role of estrogen during growth and development on the dimensions of the maxilla and/or mandible were included. Results: 5 studies were selected to compose this systematic review. One study used zebrafish as a model. Two studies used female mice and 2 studies used female rats as a model. Two studies treated the animals with estrogen. Four studies demonstrated that estrogen has an effect on mandible dimension and 2 studies demonstrated that estrogen has an effect on maxilla. One study did find an association between estrogen deficiency and mandible/maxilla dimensions Conclusion: The current evidence suggested that both, increased and decreased levels of estrogen, have an effect on the maxilla and mandible dimensions.","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43933864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-06-26DOI: 10.5195/D3000.2019.85
Sara Barna, Jean A. O’Donnell, M. Oakley
{"title":"Systematic literature review of emergency department physicians’ confidence to treat dental pain and the frequency with which they prescribe pain medications: Considerations for improved outcomes.","authors":"Sara Barna, Jean A. O’Donnell, M. Oakley","doi":"10.5195/D3000.2019.85","DOIUrl":"https://doi.org/10.5195/D3000.2019.85","url":null,"abstract":"Opioid analgesics, when taken as prescribed, are effective therapeutic options that provide pain relief for moderate to severe pain. The use of opioids in the treatment of pain has been increasing in the U.S. at an alarming rate, possibly contributing to the simultaneous rise in opioid abuse. Emergency departments play a major role in managing patients who present in pain, with approximately 10% of all opioid analgesic prescriptions written in hospital emergency departments. It is estimated that dental pain patients represent between 0.3-4% of the overall patient emergency department workload. Yet, the literature suggests that many of these physicians may not have sufficient training in handling dentofacial emergencies. The goal of this study was to systematically review the available literature on the topics of: 1) emergency department physicians’ training related to treating dental pain patients, and 2) the frequency in which they prescribe opioid medications to these patients. Methods: A systematic literature review was conducted among publications from 1985-2014 in the databases PubMed, Ovid, and Science Citation Index. The following search terms were used in this systematic literature review in order to identify the available literature of interest: “opioid and dental and emergency departments,” “dental pain and drug abuse,” “ER physicians and dental pain,” “ER physicians and drug abuse,” and “dental pain and emergency departments.” Publications in any language or country were considered, as well as editorials and commentaries. Findings: A total of 769 publications were identified. Seventeen publications met the criteria for inclusion. Eight studies commented on the emergency department physicians’ perceived “lack of training” in handling dentofacial emergencies and found that the majority of this group did not feel comfortable in managing dental patients. Nine studies assessed the frequency in which physicians prescribe pain medications to dental patients. Within these 9 studies, 5 specifically reported that between 29.6% and 81% of dental patients treated, received an “opioid” or a “narcotic” upon discharge. The remaining 4 studies in this group instead used non-specific terms that included “prescription medications,” “analgesics,” “pain medicine,” and “pharmacotherapy” to describe their findings and did not particularly report opioid prescribing trends. Of those publications rejected, 9 addressed the topic of dental pain patients presenting to non-dental providers, but did not include data that met the criteria related to emergency department prescribing frequency or physician training. Conclusions: This review of the literature suggests that emergency department physicians’ training level in treating dentofacial pain is less than ideal. It also confirms that individuals presenting to emergency departments with dental pain are a subset of the population of patients who are prescribed opioids as an analgesic. Coupling these results with th","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46481321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-06-26DOI: 10.5195/D3000.2019.86
Amanda de Sousa Galdino, T. Ramos, Vitor Marques Filgueiras, R. Lacerda
{"title":"Applicability of Moyer’s prediction tables to estimate the mesio-distal diameter of canines and premolars","authors":"Amanda de Sousa Galdino, T. Ramos, Vitor Marques Filgueiras, R. Lacerda","doi":"10.5195/D3000.2019.86","DOIUrl":"https://doi.org/10.5195/D3000.2019.86","url":null,"abstract":"Objective: The aim of this study was to verify the applicability of Moyer’s prediction tables to estimate the mesio-distal diameter of canines and pre-molars in a population of North-Eastern Brazil. Materials and Methods: A sample of 100 plaster moulds of 12-18-year-old patients was selected from the dental archives of the Brazilian Association of Orthodontists Dental School Clinic in the city of João Pessoa, State of Paraiba. Analyses were performed with R software (version 3.1.3). The upper and lower canines and premolars on both sides of the arch were measured. Data Analysis: Linear regression analysis was used to assess the closeness of the estimated values in each percentile of Moyer’s prediction table. Analyses were performed at a significance level of 5%. Results: Gender dimorphism (P < 0.001) was found in both upper and lower arches. In the upper arch, the best regression models for data analysis of female, male and both were, respectively, p5 and p6”, p25 and p35, and p35 and 75, whereas in the lower arch were p15, p35 and p75, with “p75 being the best-fitted percentile following application of correction equations for both genders. Conclusions: The Moyer’s prediction table can be applied for estimating the mesio-distal diameters of canines and pre-molars, provided that a correction factor is used for the population under study.","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42801247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-02-13DOI: 10.4172/2161-1122-C7-046
pDavid G Gillamp
{"title":"Management of post-operative sensitivity following periodontal treatment","authors":"pDavid G Gillamp","doi":"10.4172/2161-1122-C7-046","DOIUrl":"https://doi.org/10.4172/2161-1122-C7-046","url":null,"abstract":"In my 15 plus years working as a dental hygienist in long term care facilities, I have seen the most reprehensible oral care imaginable. I have witnessed dentures that had not been removed or cleaned in years. I have seen tube-fed residents who had not had their teeth brushed in months because of the staff ’s failure to see the necessity of providing oral homecare. I recently treated a patient who had so much tartar build up on his lower anterior teeth that he could not close his mouth or properly chew his food. I have listened to the countless, heart-wrenching accounts of elders so embarrassed by their dental condition that they were ashamed to smile or even let me examine their mouths. Dental health plays a significant role in mental and emotional health and well-being. Therefore, caregiver provision of proper oral homecare helps maintain the dignity of the geriatric community. Whether the neglect is due to caregivers’ lack of knowledge or lack of compassion, the result is detrimental to the systemic health of the elderly. Uncontrolled oral bacteria can lead to pneumonia, diabetes, strokes, and heart attacks. It has even been linked to Alzheimer’s Disease. Frequently, cognitive impairment intensifies preexisting oral problems. For instance, elders with Alzheimer’s typically have poor oral care and a higher incidence of oral diseases. The most deplorable aspect of this situation is the fact that it is readily preventable. The quality of life and systemic health of residents in long term care facilities can be significantly improved by simple, consistent, and effective oral care practices. 31 Open Journal of Geriatrics V1 . I1 . 2018 Solh 2011) Death rates vary from 1 to 48% and are associated with age, comorbidities, and the severity of the disease (Welte et al. 2012). Clinically, residents feel sick and present with cough, purulent sputum, fever, sweats, pain, and suffocation hazard. Very old residents lack these classic symptoms and rather present with disorientation and some may even fall (Janssens and Krause 2004). Silent aspiration of treacherous oral microorganisms resulting from poor oral hygiene is a major contributing factor to nursing home pneumonia. It can be found in places we would never suspect. There is evidence for the first time that denture wearing during sleep doubles the risk of pneumonia in very old people (Iinuma et al. 2014). Microorganisms of denture plaque associated with periodontal disease were found in the lungs of patients who were denture wearers. (Imsand et al. 2002). The tongue is another place that harmful oral microorganisms populate. A study was conducted on seventy-one edentulous residents of long term care facilities age 65 years and older. The study evaluated the quantity of tongue-coating and found that elderly residents whose tongues were coated had “significantly higher salivary bacterial counts” than those whose tongues were not coated. The study also revealed that the risk of developing pneumonia was hi","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70619802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dentistry 3000Pub Date : 2019-01-01DOI: 10.35248/2161-1122.19.9.541
P. Goel, Harshaminder Grewal, V. Gupta
{"title":"Evaluation of andalpha;-Smooth Muscle Actin (andalpha;-SMA) in Intraosseous Lesions of Jaw-An Immunohistochemical Study","authors":"P. Goel, Harshaminder Grewal, V. Gupta","doi":"10.35248/2161-1122.19.9.541","DOIUrl":"https://doi.org/10.35248/2161-1122.19.9.541","url":null,"abstract":"Introduction: Fibroblasts associated with tumor stroma called as “peritumoral fibroblasts”, “cancer-associated fibroblasts” or “myofibroblasts” encompass heterogenous and multifunctional cell populations, manifesting various phenotypes. Myofibroblasts are known to play a pivotal role in normal growth and development, wound healing, organ fibrosis and cancers. The role of myofibroblasts in the remodeling of ECM in various intraosseous lesions may affect the nature and growth of these lesions by influencing matrix formation, cellular proliferation, cellular migration, angiogenesis, and extracellular proteolytic activity. Aim and Objective: The following study was undertaken to evaluate the expression of α- smooth muscle actin in intraosseous lesions of the jaw and to correlate their role with the pathogenesis or progression of these diseases if any. Material and Methods: A total of 75 cases of Intraosseous lesions of the jaw formed the study sample. The study sample was further categorized into six groups as- Inflammatory lesions, Reactive Lesions, Benign Neoplasms, Malignant Neoplasms, Odontogenic Cysts, and Fibro-osseous Lesions. The sections were stained using Standard Hematoxylin and Eosin staining and Immunohistochemical staining for α-Smooth Muscle Actin (α- SMA). The sections were scanned at low magnification to identify positively stained areas (Hot Spots). Maximum of 10 hotspots (positive fields) were selected for quantitative scores. Statistical Analysis: Data was examined for statistical significance (p-value) using One-way analysis of variance (ANOVA) for four groups and Post Hoc tests for multiple comparisons (Tukey HSD). Results: Group II (Reactive lesions) shows highest immunoexpression (2.56) followed by Group IV (Malignant neoplasms-1.83), Group III (Benign neoplasms-1.67), Group VI (Fibro-osseous lesions-1.57), Group V (Odontogenic jaw cysts-1.50) and Group I (Inflammatory lesions-0.40). Conclusion: The understanding of expression and activity of myofibroblasts may thus be necessary for the application of anti-Myofibroblastic drugs in the therapy.","PeriodicalId":37056,"journal":{"name":"Dentistry 3000","volume":"85 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69983105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}