Comparative Migration Studies最新文献_第7页

The effect of co-ethnic social capital on immigrants' labor market integration: a natural experiment 共同种族社会资本对移民劳动力市场整合的影响:一个自然实验

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-04-12 DOI: 10.1186/s40878-022-00289-x

K. Gërxhani, Yuliya Kosyakova

引用次数: 5

Race and sameness: on the limits of beyond race and the art of staying with the trouble 种族与同一性:论超越种族的界限与与麻烦相伴的艺术

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-04-05 DOI: 10.1186/s40878-022-00287-z

A. M’charek

引用次数: 2

Complex Loop Dynamics Underpin Activity, Specificity, and Evolvability in the (βα)₈ Barrel Enzymes of Histidine and Tryptophan Biosynthesis. 组氨酸和色氨酸生物合成中 (βα)8 桶酶的活性、特异性和可进化性的复杂环路动力学基础

IF 8.5 2区社会学

Comparative Migration Studies Pub Date : 2022-04-04 eCollection Date: 2022-04-25 DOI: 10.1021/jacsau.2c00063

Adrian Romero-Rivera, Marina Corbella, Antonietta Parracino, Wayne M Patrick, Shina Caroline Lynn Kamerlin

{"title":"Complex Loop Dynamics Underpin Activity, Specificity, and Evolvability in the (βα)8 Barrel Enzymes of Histidine and Tryptophan Biosynthesis.","authors":"Adrian Romero-Rivera, Marina Corbella, Antonietta Parracino, Wayne M Patrick, Shina Caroline Lynn Kamerlin","doi":"10.1021/jacsau.2c00063","DOIUrl":"10.1021/jacsau.2c00063","url":null,"abstract":"Enzymes are conformationally dynamic, and their dynamical properties play an important role in regulating their specificity and evolvability. In this context, substantial attention has been paid to the role of ligand-gated conformational changes in enzyme catalysis; however, such studies have focused on tremendously proficient enzymes such as triosephosphate isomerase and orotidine 5'-monophosphate decarboxylase, where the rapid (μs timescale) motion of a single loop dominates the transition between catalytically inactive and active conformations. In contrast, the (βα)8-barrels of tryptophan and histidine biosynthesis, such as the specialist isomerase enzymes HisA and TrpF, and the bifunctional isomerase PriA, are decorated by multiple long loops that undergo conformational transitions on the ms (or slower) timescale. Studying the interdependent motions of multiple slow loops, and their role in catalysis, poses a significant computational challenge. This work combines conventional and enhanced molecular dynamics simulations with empirical valence bond simulations to provide rich details of the conformational behavior of the catalytic loops in HisA, PriA, and TrpF, and the role of their plasticity in facilitating bifunctionality in PriA and evolved HisA variants. In addition, we demonstrate that, similar to other enzymes activated by ligand-gated conformational changes, loops 3 and 4 of HisA and PriA act as gripper loops, facilitating the isomerization of the large bulky substrate ProFAR, albeit now on much slower timescales. This hints at convergent evolution on these different (βα)8-barrel scaffolds. Finally, our work reemphasizes the potential of engineering loop dynamics as a tool to artificially manipulate the catalytic repertoire of TIM-barrel proteins.","PeriodicalId":37051,"journal":{"name":"Comparative Migration Studies","volume":"9 1","pages":"943-960"},"PeriodicalIF":8.5,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87851656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A crisis mode in migration governance: comparative and analytical insights 迁移治理中的危机模式:比较和分析的见解

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-03-21 DOI: 10.1186/s40878-022-00284-2

Zeynep Sahin-Mencutek, Soner O. Barthoma, N. E. Gökalp-Aras, A. Triandafyllidou

引用次数: 12

Correction to: Beyond race? 更正:超越种族?

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-01-31 DOI: 10.1186/s40878-022-00278-0

S. Saharso, Tabea Scharrer

引用次数: 0

We are all migrants 我们都是移民

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-01-13 DOI: 10.1186/s40878-021-00276-8

J. Valsiner

引用次数: 2

COVID-19 pandemic and the changing views of mobility: the case of Nepal-Malaysia migration corridor. COVID-19大流行与流动观念的变化:以尼泊尔-马来西亚移民走廊为例。

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-01-01 Epub Date: 2022-11-01 DOI: 10.1186/s40878-022-00320-1

Andika Wahab, Mashitah Hamidi

引用次数: 1

Comparative perspectives on migration, diversities and the pandemic. 关于移徙、多样性和流行病的比较观点。

IF 3.3 2区社会学

Comparative Migration Studies Pub Date : 2022-01-01 Epub Date: 2022-09-02 DOI: 10.1186/s40878-022-00306-z

Magdalena Arias Cubas, Anju Mary Paul, Jacques Ramírez, Sanam Roohi, Peter Scholten

引用次数: 0

Plural violence(s) and migrants' transnational engagement with democratic politics: the case of Colombians in Europe. 多元暴力和移民对民主政治的跨国参与:欧洲哥伦比亚人的案例。

IF 3.5 2区社会学

Comparative Migration Studies Pub Date : 2022-01-01 Epub Date: 2022-06-15 DOI: 10.1186/s40878-022-00298-w

Anastasia Bermudez

{"title":"Plural violence(s) and migrants' transnational engagement with democratic politics: the case of Colombians in Europe.","authors":"Anastasia Bermudez","doi":"10.1186/s40878-022-00298-w","DOIUrl":"https://doi.org/10.1186/s40878-022-00298-w","url":null,"abstract":"This article explores how multiple, interrelated violence(s) shape the ways in which migrants relate to democratic politics transnationally. It takes as a departing point the literature on violent democracies and violent pluralism in the Latin American context, and more specifically the situation in Colombia, where democratic institutions coexist with plural violence(s). Following on from studies of migrant transnational politics, the analysis focuses on the Colombian diaspora and how migrants coming from violent democracies engage politically with the home country. Based on extensive research with Colombian migrants in Europe since the mid-90s, the article shows how despite different motivations for migrating, origin-country violence plays a significant role in the lives of many Colombians abroad. It then explores how violence influences migrants' transnational politics. Migrating from a context of pervasive violence(s) can affect migrants' sense of transnational belonging as well as increase mistrust and indifference towards formal democratic processes. However, the situation in the home country, together with being exposed to different conditions in the host society, can also motivate migrants to participate transnationally in initiatives to end the violence, thus increasing cooperation and trust.","PeriodicalId":37051,"journal":{"name":"Comparative Migration Studies","volume":" ","pages":"25"},"PeriodicalIF":3.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39999622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Covid-19 and female migrants: policy challenges and multiple vulnerabilities. Covid-19 和女性移民：政策挑战和多重脆弱性。

IF 4.3 2区社会学

Comparative Migration Studies Pub Date : 2022-01-01 Epub Date: 2022-06-01 DOI: 10.1186/s40878-022-00295-z

Dudziro Nhengu

引用次数: 0