CJC OpenPub Date : 2025-07-01DOI: 10.1016/j.cjco.2025.02.001
Razan Salem MD , Katharina Fay MD , Philipp Kaiser MD , Afsaneh Karimian-Tabrizi , Eva Herrmann PhD , Andreas Winter MD , Jan Hlavicka MD, PhD , Florian Hecker MD , Anton Moritz MD , Thomas Walther MD , Tomas Holubec MD, PhD
{"title":"Minimally Invasive Mitral Valve Surgery: Long-Term (20-Year) Follow-Up After Right Anterolateral Minithoracotomy","authors":"Razan Salem MD , Katharina Fay MD , Philipp Kaiser MD , Afsaneh Karimian-Tabrizi , Eva Herrmann PhD , Andreas Winter MD , Jan Hlavicka MD, PhD , Florian Hecker MD , Anton Moritz MD , Thomas Walther MD , Tomas Holubec MD, PhD","doi":"10.1016/j.cjco.2025.02.001","DOIUrl":"10.1016/j.cjco.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>Minimally invasive mitral valve (MV) surgery (MIMVS) through right lateral minithoracotomy has evolved as the standard approach for most patients. Data on long-term functional outcomes, however, are rare. We evaluated long-term outcomes after MIMVS through right minithoracotomy for up to 21.6 years.</div></div><div><h3>Methods</h3><div>From 1997 to 2017, 301 patients with a median age of 57 years (range, 20-81; 54.5% female) underwent MIMVS through right anterolateral minithoracotomy. Follow-up data were evaluated using Kaplan–Meier analyses and competing risk analysis.</div></div><div><h3>Results</h3><div>A total of 249 patients (82.7%) underwent MV repair, and 52 (17.2%) received valve replacement. Conversion to sternotomy was required in 2 patients (0.8%), and 2 patients (0.8%) suffered perioperative stroke. The 30-day mortality rate was 3.3%. During follow-up, 21 patients required MV reoperation after a mean period of 21.6 ± 0.2 years. The cumulative incidence of reoperation at 5, 10, 15, and 20 years, respectively, was 2.0% ± 0.8%, 4.5% ± 1.2%, 6.0% ± 1.4%, and 7.0% ± 1.6%. The cumulative incidence of recurrent mitral regurgitation ≥ moderate at 5, 10, 15, and 20 years, respectively, was 4.5% ± 1.2%, 11.1% ± 1.9%, 16.4% ± 2.2%, and 20.2% ± 2.7%. The 10- and 20-year survival of all patients was 83.6% ± 2% and 55.0% ± 4%, respectively.</div></div><div><h3>Conclusions</h3><div>MIMVS can be performed safely with very good perioperative outcomes, a low incidence of mortality, and excellent long-term valve performance.</div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 7","pages":"Pages 879-886"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CJC OpenPub Date : 2025-07-01DOI: 10.1016/j.cjco.2025.04.011
Max W. Maffey MBBS , Adrian A. Kuchtaruk BSc , Abdulla A. Damluji MD, PhD , Santiago García MD , Islam Y. Elgendy MD , Pedro Villablanca MD, MSc , Francesco Moroni MD , Martin Denicolai MD , Mamas A. Mamas BMBCh, DPhil , Rodrigo Bagur MD, PhD, FRCPC, DRCPSC, FAHA, FSCAI
{"title":"Association of Frailty With Readmissions and Outcomes After Impella Mechanical Circulatory Support","authors":"Max W. Maffey MBBS , Adrian A. Kuchtaruk BSc , Abdulla A. Damluji MD, PhD , Santiago García MD , Islam Y. Elgendy MD , Pedro Villablanca MD, MSc , Francesco Moroni MD , Martin Denicolai MD , Mamas A. Mamas BMBCh, DPhil , Rodrigo Bagur MD, PhD, FRCPC, DRCPSC, FAHA, FSCAI","doi":"10.1016/j.cjco.2025.04.011","DOIUrl":"10.1016/j.cjco.2025.04.011","url":null,"abstract":"<div><h3>Background</h3><div>Frailty is associated with a greater risk of readmission after cardiovascular procedures. However, the impact of frailty on readmission rates and outcomes after Impella mechanical circulatory support (MCS) remains unknown. We aimed to explore the impact of frailty on readmission outcomes in patients who received Impella MCS.</div></div><div><h3>Methods</h3><div>Using the National Readmissions Database, patients aged 65 years and older who received Impella MCS between January 2016 and December 2020 were identified. Frailty was determined by the Hospital Frailty Risk Score (HFRS), which stratifies patients into 3 frailty risk categories as low (<5), intermediate (5-15), and high (>15), with intermediate- and high-risk groups defined as frail. The impact of frailty on short-term (within 30 days) and midterm (31-180 days) readmission rates and in-hospital outcomes was assessed.</div></div><div><h3>Results</h3><div>Of the 16,289 patients identified in the 30-day cohort, 8647 (53.1%) were identified as frail (HFRS ≥5) and 2185 (13.4%) had an unplanned readmission at 30 days. After adjusting for age, sex and comorbidities, frailty status (HFRS ≥5) was associated with a greater risk of 30-day readmission (odds ratio [OR] 1.27, 95% confidence interval [CI] 1.17-1.37), death (OR 2.0, 95% CI 1.22-3.30), major adverse events (OR 1.73, 95% CI 1.29-2.33), length of stay >4 days (OR 1.80, 95% CI 1.44-2.26) and greater hospitalization expenditures (OR 1.44, 95% CI 1.17-1.80) during readmission. Of the 6497 patients identified in the 31-180-day cohort, 3521 (54.2%) were considered frail and 1809 (27.8%) experienced unplanned readmissions. An HFRS ≥5 was associated with a greater risk of readmission (OR 2.10, 95% CI 1.88-2.34), in-hospital death (OR 3.02, 95% CI 1.33-6.86), length of stay >4 days (OR 1.66, 95% CI 1.29-2.14), and greater hospital expenditures (OR 1.36, 95% CI 1.05-1.75) during 31-180-day readmission.</div></div><div><h3>Conclusions</h3><div>Frailty is common among patients undergoing Impella MCS and is associated with higher rates of readmission and adverse outcomes during readmission.</div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 7","pages":"Pages 972-985"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CJC OpenPub Date : 2025-07-01DOI: 10.1016/j.cjco.2025.05.004
Yiwei Wang MD, PhD , Mengen Zhai MD, PhD , Ping Jin MD, PhD , Zhenchao Wang MD, PhD , Rongji Zhang MD, PhD , Yang Liu MD, PhD , Jian Yang MD, PhD
{"title":"Transcatheter Closure of a Complex Aorta–Right Atrial Fistula Following Surgical Repair of an Aortic Dissection with 3-Dimensional Printing Guidance","authors":"Yiwei Wang MD, PhD , Mengen Zhai MD, PhD , Ping Jin MD, PhD , Zhenchao Wang MD, PhD , Rongji Zhang MD, PhD , Yang Liu MD, PhD , Jian Yang MD, PhD","doi":"10.1016/j.cjco.2025.05.004","DOIUrl":"10.1016/j.cjco.2025.05.004","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 7","pages":"Pages 932-935"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CJC OpenPub Date : 2025-07-01DOI: 10.1016/j.cjco.2025.04.008
Sandra Ofori MBBS, PhD , Michael K. Wang MD , Ekaterine Popova MD, PhD , William F. McIntyre MD, PhD , Matthew Chan MBBS, PhD , Daniel I. Sessler MD , Veronesi Giulia MD , Mark Warwas MD , Kumar Balasubramanian MSc , Vikas Tandon MD , Christain Finley MD, MPH , Gonzalez Tallada Anna MD , Juan Cata MD , Sadeesh Srinathan MD , Cara Reimer MD , Sean McLean MD, FRCPC , Juan Carlos Trujillo MD, PhD , Edith Fleischmann MD , Luca Voltolini MD , Patricia Cruz MD , David Conen MD, MPH
{"title":"Smoking, Colchicine and Postoperative Outcomes in Thoracic Surgery: Post Hoc Analysis of the COP-AF Randomized Controlled Trial","authors":"Sandra Ofori MBBS, PhD , Michael K. Wang MD , Ekaterine Popova MD, PhD , William F. McIntyre MD, PhD , Matthew Chan MBBS, PhD , Daniel I. Sessler MD , Veronesi Giulia MD , Mark Warwas MD , Kumar Balasubramanian MSc , Vikas Tandon MD , Christain Finley MD, MPH , Gonzalez Tallada Anna MD , Juan Cata MD , Sadeesh Srinathan MD , Cara Reimer MD , Sean McLean MD, FRCPC , Juan Carlos Trujillo MD, PhD , Edith Fleischmann MD , Luca Voltolini MD , Patricia Cruz MD , David Conen MD, MPH","doi":"10.1016/j.cjco.2025.04.008","DOIUrl":"10.1016/j.cjco.2025.04.008","url":null,"abstract":"<div><h3>Background</h3><div>To determine, among patients who underwent major noncardiac thoracic surgery, the association between smoking and perioperative atrial fibrillation (AF) and myocardial injury after noncardiac surgery (MINS), and whether the effect of colchicine use on these outcomes varied by smoking status.</div></div><div><h3>Methods</h3><div>This study is a subgroup analysis of the Colchicine for the Prevention of Perioperative Atrial Fibrillation (COP-AF) randomized clinical trial. A total of 3209 participants who underwent major noncardiac thoracic surgery were randomized to receive colchicine, 0.5 mg twice daily, or identical placebo, for 10 days starting 2-4 hours before surgery. The co-primary outcomes were clinically significant perioperative AF and MINS during the 14-day follow-up.</div></div><div><h3>Results</h3><div>A total of 687 (21.4%) were current smokers, 1577 (49.1%) were former smokers, and 945 (29.5%) were never smokers. AF occurred in 7.7%, 7.6%, and 5.3%, and MINS occurred in 21.0%, 19.7%, and 17.6% of current, former, and never smokers, respectively. Compared to never smokers, the adjusted hazard ratio for AF was 1.72 (95% confidence interval [CI] 1.07-2.77, <em>P</em> = 0.02) in current smokers and 1.46 (95% CI 0.99-2.16, <em>P</em> = 0.06) in former smokers, and the adjusted hazard ratio for MINS was 1.16 (95% CI 0.87-1.54, <em>P</em> = 0.32) in current smokers and 1.02 (95% CI 0.81-1.28, <em>P</em> = 0.88) in former smokers. No interaction occurred between smoking status and colchicine allocation for AF (interaction <em>P,</em> 0.82) or MINS (interaction <em>P</em>, 0.08).</div></div><div><h3>Conclusions</h3><div>Current smoking was associated with a small but increased risk of perioperative AF but not MINS after thoracic surgery. The effect of colchicine use on either outcome was not modified by smoking status.</div></div><div><h3>Clinical Trial Registration</h3><div><span><span>NCT03310125</span><svg><path></path></svg></span></div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 7","pages":"Pages 860-870"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CJC OpenPub Date : 2025-06-01DOI: 10.1016/j.cjco.2025.04.052
L. Moon, N. Tegg, C.M. Norris
{"title":"Empowering Korean Immigrant Women Through Culturally Tailored Cardiovascular Health Education: An Educational Tool Creation","authors":"L. Moon, N. Tegg, C.M. Norris","doi":"10.1016/j.cjco.2025.04.052","DOIUrl":"10.1016/j.cjco.2025.04.052","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Pages S13-S14"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CJC OpenPub Date : 2025-06-01DOI: 10.1016/j.cjco.2025.04.032
K. Abdoun , M. Fortin , L. Brunet , M. Shen, É. Bédard, P. Chetaille, M.-A. Clavel
{"title":"Effect of Pregnancy on the Progression of Aortic and Aortic Valve Disease in Patients With Bicuspid Aortic Valves","authors":"K. Abdoun , M. Fortin , L. Brunet , M. Shen, É. Bédard, P. Chetaille, M.-A. Clavel","doi":"10.1016/j.cjco.2025.04.032","DOIUrl":"10.1016/j.cjco.2025.04.032","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Page S6"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}