Medicina Clinica Practica最新文献

{"title":"Melatonin treatment in patients with atypical facial pain: A randomized, double-blind, placebo-controlled clinical trial","authors":"Tahereh Nosratzehi","doi":"10.1016/j.mcpsp.2024.100430","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100430","url":null,"abstract":"<div><h3>Background</h3><p>The present study was carried out to evaluate the effect of melatonin and placebo in the patients with atypical facial pain (AFP).</p></div><div><h3>Method</h3><p>This double blind randomized controlled study was carried out on 30 patients who were suffering from AFP. During this period, patients were divided in 2 study and control groups. Then, they were treated with melatonin. Melatonin group used four 3-mg daily and placebo group received 4 placebo which were similar in size, shape, color with melatonin until the end of treatment, and then the severity of burning sensation was measured by physician. Sleep quality was measured using the visual analog scale using the Petersburg questionnaire.</p></div><div><h3>Result</h3><p>The results of the present study show that the use of melatonin and placebo in patients with AFP reduces sensation and improves their sleep quality, although it may not reduce it completely. In this study, severity of burning was 5.71<!--> <!-->±<!--> <!-->1.42 after treatment in the study group and 5.93<!--> <!-->±<!--> <!-->2.65 in the control group, which was not statistically significant (<em>p</em> <!-->=<!--> <!-->.46). The mean score of sleep before treatment was not significantly different between the study (9<!--> <!-->±<!--> <!-->1.23) and the control (8<!--> <!-->±<!--> <!-->1.56) groups. The mean score of sleep after treatment between the study group (8<!--> <!-->±<!--> <!-->1.45) and the control group (7<!--> <!-->±<!--> <!-->1.23) was not significantly different (<em>p</em> <!-->=<!--> <!-->.43).</p></div><div><h3>Conclusion</h3><p>According to the result of the study, melatonin was not superior placebo in treatment of AFP.</p></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 3","pages":"Article 100430"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000053/pdfft?md5=773be6dd66de6b979d5c724771dd0fe0&pid=1-s2.0-S2603924924000053-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobacterium abscessus infection associated with mesotherapy injections","authors":"Julio C. Salas-Alanís ,&nbsp;Gerardo Rivera-Silva ,&nbsp;Mauricio Salas-Garza ,&nbsp;David I. Orozco-Pasadas ,&nbsp;Raymundo Garza-Martínez ,&nbsp;María G. Moreno-Treviño","doi":"10.1016/j.mcpsp.2024.100452","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100452","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 4","pages":"Article 100452"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000272/pdfft?md5=0bad6f64c60724a3f453a806de412f2e&pid=1-s2.0-S2603924924000272-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141438833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keratoderma palmoplantaris varians","authors":"Gerardo Rivera-Silva ,&nbsp;Luis F.P. Blanco-Ortega ,&nbsp;María G. Moreno-Treviño ,&nbsp;Julio C. Salas-Alanís ,&nbsp;Ma. Guadalupe Treviño-Alanís ,&nbsp;José G. Silva-Hernández","doi":"10.1016/j.mcpsp.2024.100453","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100453","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 4","pages":"Article 100453"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000284/pdfft?md5=924cfc77df206cc1433f4858933822e2&pid=1-s2.0-S2603924924000284-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141438834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncommon complication of late perforation of the right atrium with active fixation atrial electrode","authors":"Lorenzo Socias Crespí ,&nbsp;Tomas Ripoll-Vera ,&nbsp;Francisco Trucco Espinosa","doi":"10.1016/j.mcpsp.2024.100450","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100450","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 4","pages":"Article 100450"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000259/pdfft?md5=a43aac0dae34cae3f959a093bc75627c&pid=1-s2.0-S2603924924000259-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141434711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aneurisma de aorta torácica ascendente simulando un tumor hiliar derecho","authors":"Daniel Manzur-Sandoval,&nbsp;Jorge Hilarino Sánchez-Zepeda,&nbsp;Alejandro Sierra-González de Cossio,&nbsp;Edgar García-Cruz,&nbsp;Gustavo Rojas-Velasco","doi":"10.1016/j.mcpsp.2024.100451","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100451","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 4","pages":"Article 100451"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000260/pdfft?md5=568ef698eb05d50db80fc0cd608a87a1&pid=1-s2.0-S2603924924000260-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141438835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Características clínico-terapéuticas y factores de riesgo de mortalidad de los pacientes ingresados por infección por SARS-CoV-2 a lo largo de 6 ondas epidémicas","authors":"Beatriz Isidoro Fernández ,&nbsp;Lourdes Sainz de los Terreros Soler ,&nbsp;Maria Teresa García Benayas ,&nbsp;Silvia Buendía Bravo ,&nbsp;Cristina Gastalver Martín ,&nbsp;Adrián García Romero ,&nbsp;Raúl Castañeda-Vozmediano","doi":"10.1016/j.mcpsp.2024.100446","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100446","url":null,"abstract":"<div><h3>Introduction</h3><p>The clinical characteristics and treatment received by patients hospitalized with COVID-19 have changed over time. The objective was to analyze the clinicaltherapeutic evolution of patients in the epidemic waves and estimate a predictive model for mortality.</p></div><div><h3>Methods</h3><p>Retrospective cross-sectional study considering patients admitted with confirmed SARS-CoV-2 infection until March 2022. Sociodemographic variables, comorbidities and treatments were collected and a predictive model for mortality was created using multivariate logistic regression.</p></div><div><h3>Results</h3><p>1,784 patients were included. Significant differences were found between the epidemic waves with respect to age, sex, arterial hypertension, diabetes mellitus, obesity and chronic kidney disease. Ceftriaxone, azithromycin, hydroxychloroquine, methylprednisolone and lopinavir-ritonavir were the most frequently used drugs in the first wave. Amoxicillin, dexamethasone and tocilizumab were prescribed more frequently in successive waves. The percentage of deaths varied from 5.6% in the fourth wave to 14.1% in the third (p<!--> <!-->&lt;<!--> <!-->0.001). The resulting factors associated with mortality (OR; 95% CI) were ICU admission (56.5; 27.4-121), age (1.09; 1.08-1.11), days of admission (0.98; 0.96-0.99), chronic kidney disease (1.67; 1.16-2.40) and having received treatment with tocilizumab (2.49; 1.43-4.30), dexamethasone (1.58; 1.10-2.26) and methylprednisolone (2.46; 1.63-3.68). The area under the curve achieved by the model was 0.863.</p></div><div><h3>Conclusion</h3><p>There are significant clinical-therapeutic differences in patients along the first six epidemic waves. Knowledge of mortality risk factors will allow the detection of hospitalized patients at higher risk and early optimization of their therapeutic management.</p></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 3","pages":"Article 100446"},"PeriodicalIF":0.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000211/pdfft?md5=fd8d9cf854c1a1a3b8574860c653e64f&pid=1-s2.0-S2603924924000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141434252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteochondritis of the ischiopubic synchondrosis: Don't confuse it with a tumor!","authors":"Aleix Jareno-Badenas,&nbsp;Gary Amseian,&nbsp;Valèria Richart,&nbsp;Marta Porta-Vilaró","doi":"10.1016/j.mcpsp.2024.100445","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100445","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 4","pages":"Article 100445"},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S260392492400020X/pdfft?md5=d90cbc0adff7f9e5e1c02f26e3806d3f&pid=1-s2.0-S260392492400020X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141298230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive Angiosarcoma of the Face","authors":"Inês P. Amaral ,&nbsp;Madalena P. Correia ,&nbsp;Paulo Filipe","doi":"10.1016/j.mcpsp.2024.100449","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100449","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 4","pages":"Article 100449"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000247/pdfft?md5=a17154c9bb5f63cf6720f8c2ae6a8314&pid=1-s2.0-S2603924924000247-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141239487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary syphilis","authors":"Julio C. Salas-Alanís ,&nbsp;Mauricio Salas-Garza ,&nbsp;María G. Moreno-Treviño ,&nbsp;Ana C. Gómez-Barraza ,&nbsp;Gerardo Rivera-Silva","doi":"10.1016/j.mcpsp.2024.100448","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100448","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 3","pages":"Article 100448"},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000235/pdfft?md5=2418dba1e9cd91e7a2c832165348b4ac&pid=1-s2.0-S2603924924000235-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of antigen-based rapid test for Chlamydia trachomatis in comparison with polymerase chain reaction test","authors":"Manh Tuan Ha ,&nbsp;Thi Luyen Pham ,&nbsp;Tuan Anh Nguyen ,&nbsp;Viet Tung Le","doi":"10.1016/j.mcpsp.2024.100447","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100447","url":null,"abstract":"<div><h3>Background</h3><p>Rapid tests for diagnosing <em>Chlamydia trachomatis</em> infection can facilitate patient treatment and reduce transmission, as patients can receive treatment during the same visit. This study aims to evaluate the performance of the rapid test compared to the PCR test for diagnosing <em>C. trachomatis</em> infection to assess its clinical applicability.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted on participants aged &gt;<!--> <!-->18 years with symptoms of genital discharge. The performance of the rapid test was evaluated using the PCR test as the gold-standard.</p></div><div><h3>Results</h3><p>A total of 196 eligible patients were selected for the study. Females accounted for 68.4%, and those aged over 25 years represented 73.0% of the total. The prevalence of <em>C. trachomatis</em> infection was 14.3%. The overall return rate was 41.8%. The <em>Chlamydia</em> rapid test demonstrated a sensitivity of 53.6% (95% CI: 46.6–60.5%), specificity of 86.3% (95% CI: 81.5–91.1%), positive-predictive value of 39.5% (95% CI: 32.6–46.3%), and negative-predictive value of 91.8% (95% CI: 87.9–95.6%). The sensitivity of the rapid test was significantly higher in females, ≥<!--> <!-->25 years, those with past STIs, and symptoms including pruritus, dysuria, and purulent discharge than their counterparts (<em>p</em> <!-->&lt;<!--> <!-->.05).</p></div><div><h3>Conclusion</h3><p>While the <em>Chlamydia</em> rapid test is less sensitive than the PCR test, it is easy to implement, cost-effective, provides quick results, and allows more patients to receive treatment during the same visit compared to the PCR test. The rapid test still holds value in managing <em>C. trachomatis</em> infection in resource-limited settings, particularly with a low return rate.</p></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"7 3","pages":"Article 100447"},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000223/pdfft?md5=cac083fc8be21d36be61402139fd8057&pid=1-s2.0-S2603924924000223-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141096510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}