Leila N Atmowihardjo, Job R Schippers, Mark E Haaksma, Marry R Smit, Harm J Bogaard, Leo Heunks, Nicole P Juffermans, Marcus J Schultz, Henrik Endeman, Patricia van Velzen, Pieter R Tuinman, Jurjan Aman, Lieuwe D J Bos
{"title":"The diagnostic accuracy of lung ultrasound to determine PiCCO-derived extravascular lung water in invasively ventilated patients with COVID-19 ARDS.","authors":"Leila N Atmowihardjo, Job R Schippers, Mark E Haaksma, Marry R Smit, Harm J Bogaard, Leo Heunks, Nicole P Juffermans, Marcus J Schultz, Henrik Endeman, Patricia van Velzen, Pieter R Tuinman, Jurjan Aman, Lieuwe D J Bos","doi":"10.1186/s13089-023-00340-7","DOIUrl":"10.1186/s13089-023-00340-7","url":null,"abstract":"<p><strong>Background: </strong>Lung ultrasound (LUS) can detect pulmonary edema and it is under consideration to be added to updated acute respiratory distress syndrome (ARDS) criteria. However, it remains uncertain whether different LUS scores can be used to quantify pulmonary edema in patient with ARDS.</p><p><strong>Objectives: </strong>This study examined the diagnostic accuracy of four LUS scores with the extravascular lung water index (EVLWi) assessed by transpulmonary thermodilution in patients with moderate-to-severe COVID-19 ARDS.</p><p><strong>Methods: </strong>In this predefined secondary analysis of a multicenter randomized-controlled trial (InventCOVID), patients were enrolled within 48 hours after intubation and underwent LUS and EVLWi measurement on the first and fourth day after enrolment. EVLWi and ∆EVLWi were used as reference standards. Two 12-region scores (global LUS and LUS-ARDS), an 8-region anterior-lateral score and a 4-region B-line score were used as index tests. Pearson correlation was performed and the area under the receiver operating characteristics curve (AUROCC) for severe pulmonary edema (EVLWi > 15 mL/kg) was calculated.</p><p><strong>Results: </strong>26 out of 30 patients (87%) had complete LUS and EVLWi measurements at time point 1 and 24 out of 29 patients (83%) at time point 2. The global LUS (r = 0.54), LUS-ARDS (r = 0.58) and anterior-lateral score (r = 0.54) correlated significantly with EVLWi, while the B-line score did not (r = 0.32). ∆global LUS (r = 0.49) and ∆anterior-lateral LUS (r = 0.52) correlated significantly with ∆EVLWi. AUROCC for EVLWi > 15 ml/kg was 0.73 for the global LUS, 0.79 for the anterior-lateral and 0.85 for the LUS-ARDS score.</p><p><strong>Conclusions: </strong>Overall, LUS demonstrated an acceptable diagnostic accuracy for detection of pulmonary edema in moderate-to-severe COVID-19 ARDS when compared with PICCO. For identifying patients at risk of severe pulmonary edema, an extended score considering pleural morphology may be of added value.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier NCT04794088, registered on 11 March 2021. European Clinical Trials Database number 2020-005447-23.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"15 1","pages":"40"},"PeriodicalIF":3.4,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41132219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew Kamilaris, Jeffrey A Kramer, Gwen Baraniecki-Zwil, Frances Shofer, Christy Moore, Nova Panebianco, Wilma Chan
{"title":"Development of a novel observed structured clinical exam to assess clinical ultrasound proficiency in undergraduate medical education.","authors":"Andrew Kamilaris, Jeffrey A Kramer, Gwen Baraniecki-Zwil, Frances Shofer, Christy Moore, Nova Panebianco, Wilma Chan","doi":"10.1186/s13089-023-00337-2","DOIUrl":"10.1186/s13089-023-00337-2","url":null,"abstract":"<p><strong>Objectives: </strong>A pilot study was performed to develop and test an observed structured clinical exam (OSCE) for clinical ultrasound in second-year medical students. The goal was to assess a longitudinal clinical ultrasound curriculum for medical students and to help determine readiness to perform ultrasound during clinical clerkships.</p><p><strong>Methods: </strong>The OSCE contained 40 tasks over 30 min in a one-to-one examiner to examinee environment using standardized patients covering cardiac, pulmonary, and inferior vena cava (IVC) ultrasound exams along with 6 critical diagnoses. Examinees were assessed using a binary checklist approach. A two-way ANOVA analysis was performed to determine if there were differences between the day and session the OSCE was administered. Results are presented as mean ± standard deviation.</p><p><strong>Results: </strong>One hundred fifty-two students were tested with an overall mean score of 64.9 ± 17.6%. Scores between the cardiac, IVC, and lung sections varied-67.8% ± 18.8%, 62.4% ± 26.2%, and 57.1% ± 20.6%, respectively. One hundred twenty-six (82.9%) answered at least one critical diagnosis incorrectly. Students in the late session performed better than the early session (1: 60% vs 2: 69%, p = .001).</p><p><strong>Conclusions: </strong>Students performed better in later sessions. Additionally, the number of questions left blank at the end of the exam suggests that the length of the OSCE should be evaluated. Incorporating critical diagnoses was challenging for examinees. The proposed OSCE is a valuable assessment tool that could be adapted to assess student's readiness to use clinical ultrasound prior to clerkships.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"15 1","pages":"39"},"PeriodicalIF":3.4,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edith Elianna Rodríguez Aparicio, Jorge Armando Carrizosa Gonzalez, David Rene Rodriguez Lima
{"title":"Optic nerve sheath diameter at high altitude: standardized measures in healthy volunteers.","authors":"Edith Elianna Rodríguez Aparicio, Jorge Armando Carrizosa Gonzalez, David Rene Rodriguez Lima","doi":"10.1186/s13089-022-00295-1","DOIUrl":"https://doi.org/10.1186/s13089-022-00295-1","url":null,"abstract":"<p><strong>Background: </strong>Increases in the diameter of the optic nerve sheath (ONSD) on ultrasound are associated with high intracranial pressure (hICP). The normal value varies with altitude and the population studied. The objective of this study is to describe the normal values of the ONSD in a healthy adult population of the city of Bogotá, Colombia, at 2640 meters above sea level (masl).</p><p><strong>Patients and methods: </strong>A prospective observational study was conducted on a total of 247 healthy individuals recruited from May 2021 to May 2022 who were subjected to the color, low power, optic disk, safety, elevated frequency, dual (CLOSED) protocol for measuring the bilateral ONSD adjusted to the eyeball transverse diameter (ETD).</p><p><strong>Results: </strong>A total of 230 individuals were analyzed; the average ONSD of the right eye (RE) was 0.449 cm (range 0.288-0.7) and that of the left eye (LE) was 0.454 cm (range 0.285-0.698); the correlation between RE and LE was 0.93 (p < 0.005), and the correlation of the ONSD/ETD ratios for the RE and LE was lower (r<sup>2</sup> = 0.79, p < 0.005). A total of 10.8% of the studied population had values greater than 0.55 cm.</p><p><strong>Conclusions: </strong>The median ONSD and ONSD/ETD ratio in the city of Bogotá are similar to those described in other populations; however, approximately 10.8% of the healthy population may present higher values, which would limit the use of ONSD on its own for clinical decision-making, only repeated measurements with significant changes in the ONSD and ONSD/ETD or asymmetries between the measurements of both eyes linked to clinical findings would allow the diagnosis of hICP.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"46"},"PeriodicalIF":3.4,"publicationDate":"2022-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40476350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michal Maly, Masego Candy Mokotedi, Eva Svobodova, Marek Flaksa, Michal Otahal, Zdenek Stach, Jan Rulisek, Tomas Brozek, Michal Porizka, Martin Balik
{"title":"Interpleural location of chest drain on ultrasound excludes pneumothorax and associates with a low degree of chest drain foreshortening on the antero-posterior chest X-ray.","authors":"Michal Maly, Masego Candy Mokotedi, Eva Svobodova, Marek Flaksa, Michal Otahal, Zdenek Stach, Jan Rulisek, Tomas Brozek, Michal Porizka, Martin Balik","doi":"10.1186/s13089-022-00296-0","DOIUrl":"https://doi.org/10.1186/s13089-022-00296-0","url":null,"abstract":"<p><strong>Background: </strong>The role of chest drain (CD) location by bedside imaging methods in the diagnosis of pneumothorax has not been explored in a prospective study yet.</p><p><strong>Methods: </strong>Covid-19 ARDS patients with pneumothorax were prospectively monitored with chest ultrasound (CUS) and antero-posterior X-ray (CR) performed after drainage in the safe triangle. CD foreshortening was estimated as a decrease of chest drain index (CDI = length of CD in chest taken from CR/depth of insertion on CD scale + 5 cm). The angle of inclination of the CD was measured between the horizontal line and the CD at the point where it enters pleural space on CR.</p><p><strong>Results: </strong>Of the total 106 pneumothorax cases 80 patients had full lung expansion on CUS, the CD was located by CUS in 69 (86%), the CDI was 0.99 (0.88-1.06). 26 cases had a residual pneumothorax after drainage (24.5%), the CD was located by CUS in 31%, the CDI was 0.76 (0.6-0.93),p < 0.01. The risk ratio for a pneumothorax in a patient with not visible CD between the pleural layers on CUS and an associated low CDI on CR was 5.97, p˂0.0001. For the patients with a steep angle of inclination (> 50°) of the CD, the risk ratio for pneumothorax was not significant (p < 0.17). A continued air leak from the CD after drainage is related to the risk for a residual pneumothorax (RR 2.27, p = 0.003).</p><p><strong>Conclusion: </strong>Absence of a CD on CUS post drainage, low CDI on CR and continuous air leak significantly associate with residual occult pneumothorax which may evade diagnosis on an antero-posterior CR.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"45"},"PeriodicalIF":3.4,"publicationDate":"2022-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40471639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vidit Bhargava, Bereketeab Haileselassie, Samuel Rosenblatt, Mark Baker, Kevin Kuo, Erik Su
{"title":"A point-of-care ultrasound education curriculum for pediatric critical care medicine.","authors":"Vidit Bhargava, Bereketeab Haileselassie, Samuel Rosenblatt, Mark Baker, Kevin Kuo, Erik Su","doi":"10.1186/s13089-022-00290-6","DOIUrl":"https://doi.org/10.1186/s13089-022-00290-6","url":null,"abstract":"<p><strong>Background: </strong>Diagnostic and procedural point-of-care ultrasound (POCUS) change patient management with the potential to improve outcomes. Pediatric critical care medicine trainees have limited access to education and training opportunities in diagnostic POCUS in the pediatric ICU. A dearth of published pediatric ICU curricular resources restricts these educational opportunities.</p><p><strong>Methods: </strong>A 7-week longitudinal curriculum including lectures, practical skills sessions, and knowledge assessment covering core modules including (1) machine operation, (2) vascular access, (3) non-vascular procedures, (4) cardiac imaging, (5) hemodynamic assessment, (6) pulmonary imaging, and (7) abdominal imaging, was disseminated to pediatric critical care trainees and faculty at a single tertiary care pediatric hospital.</p><p><strong>Results: </strong>The knowledge of trainees and participating faculty in procedural and diagnostic POCUS improved after implementing the curriculum. Pre-test scores mean and standard deviation (59.30% ± 14.15%) improved significantly (75.60% ± 9.43%) for all learners (p < 0.001). The overall self-reported comfort in diagnostic and procedural ultrasound improved for all learners. 100% of the learners reported utilizing diagnostic POCUS in their clinical practice four months after disseminating the curriculum.</p><p><strong>Discussion: </strong>We describe a single center's approach to POCUS education with improvement in knowledge, self-reported comfort, and attitudes towards procedural and diagnostic POCUS. The curricular resources for adaptation in a similar educational context are provided.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"44"},"PeriodicalIF":3.4,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40673456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raffaele Aspide, Giacomo Bertolini, Laura Maria Beatrice Belotti, Luca Albini Riccioli, Francesco Toni, Diego Mazzatenta, Giorgio Palandri, Luigi Vetrugno, Daniele Guerino Biasucci
{"title":"The CLOSED protocol to assess optic nerve sheath diameter using color-Doppler: a comparison study in a cohort of idiopathic normal pressure hydrocephalus patients.","authors":"Raffaele Aspide, Giacomo Bertolini, Laura Maria Beatrice Belotti, Luca Albini Riccioli, Francesco Toni, Diego Mazzatenta, Giorgio Palandri, Luigi Vetrugno, Daniele Guerino Biasucci","doi":"10.1186/s13089-022-00291-5","DOIUrl":"https://doi.org/10.1186/s13089-022-00291-5","url":null,"abstract":"<p><strong>Background: </strong>Sonographic assessment of the optic nerve sheath diameter represents a promising non-invasive technique for estimation of the intracranial pressure. A wide inter-observer variability, along with a lack of a standardized protocol for the optic nerve sheath diameter measurements, could lead to over- or under-estimation. The present study was aimed at evaluating feasibility of color-Doppler for better delineating optic nerve sheath borders, comparing it to B-mode imaging, using the magnetic resonance measurements as a comparison.</p><p><strong>Methods: </strong>Optic nerve sheath diameters were evaluated using magnetic resonance by an expert radiologist in a cohort of patients with suspected idiopathic normal pressure hydrocephalus. Magnetic resonance findings were evaluated twice. In the first half of this cohort, optic nerve sheath diameters were measured using B-mode only, in the second half applying color-Doppler. Measurements obtained using these two techniques were compared to magnetic resonance imaging measurements. The Bland-Altman analysis and concordance correlation coefficient were computed to quantify the strength of agreement between the two magnetic resonance assessments. Box plots and average (± SD) were used to compare assessments by sonographic and magnetic resonance methods.</p><p><strong>Results: </strong>Fifty patients were included. MRI assessment showed a moderate concordance correlation coefficient. Optic nerve sheath diameters measured applying color-Doppler were lower (p < 0.001) and less scattered compared to B-mode assessment, which approached more to magnetic resonance measurements.</p><p><strong>Conclusions: </strong>In this cohort of patients, magnetic resonance showed high intra-rater variability in optic nerve sheath diameter assessments. Optic nerve sheath diameter assessments using color-Doppler yielded lower and less scattered diameters compared to B-mode only.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"43"},"PeriodicalIF":3.4,"publicationDate":"2022-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40432735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo Blanco, Liliana Figueroa, María Fernanda Menéndez
{"title":"Native-valve endocarditis detected by point-of-care echocardiography.","authors":"Pablo Blanco, Liliana Figueroa, María Fernanda Menéndez","doi":"10.1186/s13089-022-00294-2","DOIUrl":"https://doi.org/10.1186/s13089-022-00294-2","url":null,"abstract":"<p><strong>Background: </strong>Infective endocarditis carries a high morbidity and mortality; therefore, a rapid diagnosis and timely treatment is crucial to improve outcomes. Diagnosis of infective endocarditis is supported on echocardiogram findings.</p><p><strong>Case presentation: </strong>An adult male with history of long-term hemodialysis, presented with embolic manifestations (cerebral, skin) and fever. A large vegetation in the mitral valve and other in the tricuspid valve were detected by point-of-care transthoracic echocardiogram, while blood cultures subsequently resulted positive for methicillin-resistant Staphylococcus aureus. Despite therapeutic efforts, the patient developed into an irreversible shock and died.</p><p><strong>Conclusions: </strong>Point-of-care echocardiogram has a pivotal role in diagnosis and decision-making of infective endocarditis.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"42"},"PeriodicalIF":3.4,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40429082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamin K Nti, Whitney Phillips, Elisa Sarmiento, Frances Russell
{"title":"Effect of a point-of-care ultrasound (POCUS) curriculum on emergency department soft tissue management.","authors":"Benjamin K Nti, Whitney Phillips, Elisa Sarmiento, Frances Russell","doi":"10.1186/s13089-022-00292-4","DOIUrl":"https://doi.org/10.1186/s13089-022-00292-4","url":null,"abstract":"<p><strong>Background: </strong>Pediatric emergency department (ED) visits for superficial skin and soft tissue infections (SSTI) have steadily been increasing and point-of-care ultrasound (POCUS) continues to be an effective modality to improve management and shorter ED length of stays (LOS).</p><p><strong>Objective: </strong>We sought to determine the impact of a soft tissue POCUS curriculum on POCUS utilization, ED LOS, and cost-effectiveness.</p><p><strong>Methods: </strong>This was a retrospective pre- and post-interventional study of pediatric patients aged 0 to 17 years. Patients presenting to ED with international classification of disease 9 or 10 code for abscess or cellulitis were included. Data were collected a year before and after curriculum implementation with a 1-year washout training period. Training included continuing medical education, greater than 25 quality assured examinations, and a post-test. We compared diagnostic imaging type, ED LOS, and mean charges in patients with SSTI.</p><p><strong>Results: </strong>We analyzed data on 119 total patients, 38 pre- and 81 post-intervention. We found a significant increase in the total number of POCUS examinations performed pre- to post-curriculum intervention, 26 vs. 59 (p = 0.0017). Mean total charges were significantly decreased from $3,762 (± 270) to $2,622 (± 158; p = 0.0009). There was a significant trend towards a decrease in average ED LOS 282 (standard error of mean [SEM] ± 19) vs 185 (± 13) minutes (p = 0.0001).</p><p><strong>Conclusions: </strong>Implementation of a soft tissue POCUS curriculum in a pediatric ED was associated with increased POCUS use, decreased LOS, and lower cost. These findings highlight the importance of POCUS education and implementation in the management of pediatric SSTI.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"41"},"PeriodicalIF":3.4,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40564328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aarti Sarwal, Yash Patel, Ralph D'Agostino, Patrick Brown, Stacey Q Wolfe, Cheryl Bushnell, Casey Glass, Pamela Duncan
{"title":"Exploratory study to assess feasibility of intracerebral hemorrhage detection by point of care cranial ultrasound.","authors":"Aarti Sarwal, Yash Patel, Ralph D'Agostino, Patrick Brown, Stacey Q Wolfe, Cheryl Bushnell, Casey Glass, Pamela Duncan","doi":"10.1186/s13089-022-00289-z","DOIUrl":"https://doi.org/10.1186/s13089-022-00289-z","url":null,"abstract":"<p><strong>Background: </strong>Limited studies have evaluated the use of ultrasound for detection of intracerebral hemorrhage (ICH) using diagnostic ultrasound Transcranial Doppler machines in adults. The feasibility of ICH detection using Point of care Ultrasound (POCUS) machines has not been explored. We evaluated the feasibility of using cranial POCUS B mode imaging performed using intensive care unit (ICU) POCUS device for ICH detection with a secondary goal of mapping optimal imaging technique and brain topography likely to affect sensitivity and specificity of ICH detection with POCUS.</p><p><strong>Materials and methods: </strong>After obtaining IRB approval, a blinded investigator performed cranial ultrasound (Fujifilm, Sonosite<sup>®</sup> Xporte, transcranial and abdominal presets) through temporal windows on 11 patients with intracerebral pathology within 72 h of last CT/MRI (computed tomography scan/magnetic resonance imaging) brain after being admitted to a neurocritical care unit in Aug 2020 and Nov 2020-Mar 2021. Images were then compared to patient's CT/MRI to inform topography. Inferential statistics were reported.</p><p><strong>Results: </strong>Mean age was 57 (28-77 years) and 6/11 were female. Six patients were diagnosed with ICH, 3 with ischemic stroke, 1 subarachnoid hemorrhage, and 1 brain tumor. The sensitivity and specificity of point of care diagnosis of ICH compared to CT/MRI brain was 100% and 50%, respectively. Mean time between ultrasound scan and CT/MRI was 13.3 h (21 min-39 h). Falx cerebri, choroid calcification and midbrain-related artifacts were the most reproducible hyperechoic signals. Abdominal preset on high gain yielded less artifact than Transcranial Doppler preset for cranial B mode imaging. False positive ICH diagnosis was attributed to intracerebral tumor and midbrain-related artifact.</p><p><strong>Conclusions: </strong>Our exploratory analysis yielded preliminary data on use of point of care cranial ultrasound for ICH diagnosis to inform imaging techniques, cranial topography on B mode and sample size estimation for future studies to evaluate sensitivity and specificity of cranial POCUS in adult patients. This pilot study is limited by small sample size and over representation of ICH in the study. Cranial POCUS is feasible using POCUS machines and may have potential as a screening tool if validated in adequately powered studies.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"40"},"PeriodicalIF":3.4,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Righini, C Felicani, A Lopez, E Mazzotta, C De Molo, E Mancini, I Capelli, C Serra, G La Manna
{"title":"Medullary sponge kidney: unusual finding in kidney transplant recipient.","authors":"M Righini, C Felicani, A Lopez, E Mazzotta, C De Molo, E Mancini, I Capelli, C Serra, G La Manna","doi":"10.1186/s13089-022-00277-3","DOIUrl":"https://doi.org/10.1186/s13089-022-00277-3","url":null,"abstract":"<p><strong>Background: </strong>Medullary sponge kidney is generally considered a benign condition, gold standard for the diagnosis is urography but it has almost been replaced by UroCT that did not present the same sensibility. Although it is really rare, our sonography's findings were consistent with medullary sponge kidney in the transplanted kidneys.</p><p><strong>Case presentation: </strong>A 45-year-old woman with a long history of double-kidney transplantation complained of frequent urinary tract infections, a history of vague loin pain and came to our attention for sonography follow-up. Her kidney function was normal, we did not find signs of infections in the transplanted kidneys and urinary findings were normal. Curiously, the transplanted kidneys came from a newborn and the patient received a double-kidney transplantation in order to guarantee a satisfactory renal function.</p><p><strong>Conclusions: </strong>Despite a long history of kidney transplantation, genetic disease should not be forgotten when symptoms and images recall to specific inherited alterations. Sonography has to be considered in diagnostic path of kidney cystic disease.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":" ","pages":"39"},"PeriodicalIF":3.4,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40384172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}