Journal of Experimental Orthopaedics最新文献

{"title":"Bioplating demonstrates increasing micromovement during cyclic loading after anterior closed wedge high tibial osteotomy despite no significant difference in failure load compared to angle-stable plate fixation","authors":"Andrzej Jasina,&nbsp;Pia Metje,&nbsp;Jan-Oliver Sass,&nbsp;Jessica Hembus,&nbsp;Sjard Simons,&nbsp;Sina Gräber,&nbsp;Kira Liebau,&nbsp;Rainer Bader,&nbsp;Philipp Schuster,&nbsp;Maeruan Kebbach,&nbsp;Parisa Pourostad,&nbsp;Christoph Lutter,&nbsp;Felix Ferner","doi":"10.1002/jeo2.70911","DOIUrl":"https://doi.org/10.1002/jeo2.70911","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To biomechanically compare fixation stability after anterior closed wedge high tibial osteotomy (ACW-HTO) for posterior tibial slope (PTS) correction using trans-tuberosity “bioplating” and infra-tuberosity angle-stable plate fixation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this cadaveric biomechanical study, fresh-frozen human knee specimens were allocated in a paired donor-matched manner to the two intervention groups. Tensile load was applied to the quadriceps tendon at a fixed flexion angle using an electrodynamic testing machine. After preloading, 1000 load cycles between 50 N and 200 N were performed at 1 Hz. The specimens were then loaded to failure at 10 mm/s. Micromovement at the osteotomy gap was analysed after 200 and 800 cycles using an optical 3D system. Two-way ANOVA with Bonferroni multiple comparison testing was used, with <i>p</i> &lt; 0.05 considered statistically significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twelve cadaveric knee specimens (<i>n</i> = 6 per intervention group; mean age 79.2 ± 8.2 years) were included. No statistically significant difference in micromovement was found between the two intervention groups after 200 (<i>p</i> = 0.515) or 800 cycles (<i>p</i> = 0.889). In the “bioplating” group, micromovement increased from 0.055 ± 0.017 mm after 200 cycles to 0.069 ± 0.035 mm after 800 cycles (<i>p</i> = 0.025), whereas no significant increase occurred with angle-stable fixation (<i>p</i> = 0.518). Osteosynthesis failure load did not differ significantly between groups (643.9 ± 190.8 N vs. 566.8 ± 111.0 N, <i>p</i> = 0.422).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>No significant difference in failure load was detected between the techniques. However, “bioplating” demonstrated increasing micromovement during cyclic loading. Considering the limitations of the present biomechanical setup, superiority or inferiority of either fixation technique cannot be concluded. These findings should serve as a basis for further biomechanical testing and should be considered when selecting the surgical technique and postoperative treatment regimen in patients undergoing ACW-HTO for PTS correction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level V, controlled laboratory study.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jeo2.70911","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148943318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteochondral flake refixation using the parachute technique yields favourable clinical and radiological outcomes following acute patellar dislocation: A case series at short- to mid-term follow-up","authors":"Romed Peter Vieider,&nbsp;Yannick Ehmann,&nbsp;Svenja Höger,&nbsp;Lorenz Fritsch,&nbsp;Charlotte Schweitzer,&nbsp;Armin Runer,&nbsp;Alexander Wolfgang Marka,&nbsp;Sebastian Siebenlist,&nbsp;Julian Mehl","doi":"10.1002/jeo2.70894","DOIUrl":"10.1002/jeo2.70894","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To evaluate short- to mid-term clinical and radiological outcomes following osteochondral flake refixation with transpatellar, absorbable sutures (parachute technique) combined with concomitant medial patellofemoral ligament (MPFL) reconstruction after acute patellar dislocation. It was hypothesized that the parachute technique would yield favourable clinical and functional outcomes and demonstrate good osteochondral integration on radiographic follow-up.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A retrospective case series was conducted, including patients who underwent osteochondral flake refixation using the parachute technique following acute patellar dislocation between January 2012 and November 2023 at a minimum follow-up of 24 months. Clinical outcomes were assessed using the Visual Analogue Scale (VAS), Tegner Activity Scale (TAS), Kujala Score, International Knee Documentation Committee (IKDC) subjective score and Knee Injury and Osteoarthritis Outcome Score (KOOS). Radiological outcomes were evaluated using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) 2.0 knee score on 3.0-T magnetic resonance imaging (MRI) by three independent raters and intraclass correlation coefficient (ICC) was assessed.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Of 26 identified patients, 20 (77%) were available at final follow-up (mean age 20.8 ± 5.3 years; mean follow-up 62.2 ± 20.5 months; mean defect size 2.8 ± 1.5 cm&lt;sup&gt;2&lt;/sup&gt;). Clinical outcome scores resulted in a mean VAS of 0.5 ± 1.6, TAS of 6 (interquartile range 4–7), Kujala Score of 89.4 ± 12.5, IKDC of 86.7 ± 14.3 and total KOOS of 87.8 ± 14.1. Of all patients, 95% were satisfied with the overall result, and 90% would be willing to undergo the procedure again if necessary. Two patients (10%) required revision surgery (one patella re-dislocation, one failed osteochondral integration). The mean MOCART 2.0 score was 84 ± 8 (range: 75–95), indicating good to excellent osteochondral integration. Inter-rater reliability across the three raters was almost perfect (ICC = 0.84; 95% confidence interval 0.79–0.96).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The parachute technique yields favourable clinical and functional outcomes at short- to mid-term follow-up and demonstrates good to excellent osteochondral integration on MRI following acute patellar dislocation. The technique represents a reliable, simple and single-stage option for the treatment of retropatellar osteochondral flake fractures.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 ","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13556305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative standing–supine difference in joint line convergence angle predicts postoperative alignment change after closing-wedge high tibial osteotomy","authors":"Mitsuhiko Kubo,&nbsp;Kazuhiro Uenaka,&nbsp;Hitomi Fujikawa,&nbsp;Tsutomu Maeda,&nbsp;Kosuke Kumagai,&nbsp;Yuki Nosaka,&nbsp;Sadafumi Horikawa,&nbsp;Shinji Imai","doi":"10.1002/jeo2.70904","DOIUrl":"10.1002/jeo2.70904","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The aim of this study was to identify preoperative determinants of postoperative change in joint line convergence angle (JLCA) after closing-wedge high tibial osteotomy (CWHTO), comparing standing- and supine-based radiographic references for preoperative planning.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Consecutive patients with medial compartmental knee disorders who underwent CWHTO between February 2009 and September 2017 were retrospectively reviewed. Patients with anterior cruciate ligament reconstruction, unavailable radiographs or non-measurable radiographs were excluded. JLCA was measured on standing, supine and valgus/varus stress radiographs. Postoperative change in JLCA (cJLCA) was calculated from preoperative supine to postoperative standing JLCA (cJLCA [pre-supine to post-stand]) and from preoperative standing to postoperative standing JLCA (cJLCA [pre-stand to post-stand]). The preoperative standing-supine difference in JLCA (dJLCA) was also calculated. Associations between cJLCA and demographic and radiographic variables were evaluated using univariate and multivariable analyses.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;After excluding patients with anterior cruciate ligament reconstruction (&lt;i&gt;n&lt;/i&gt; = 1), unavailable radiographs (&lt;i&gt;n&lt;/i&gt; = 7) or non-measurable radiographs (&lt;i&gt;n&lt;/i&gt; = 4), 40 patients were included. The cohort included 29 women and 11 men, with a mean age of 60.3 years (range, 39–77 years); postoperative radiographs were obtained at a mean of 9.9 months (range, 2–14 months). Univariate analysis showed that dJLCA was positively correlated with cJLCA (pre-supine to post-stand) (&lt;i&gt;ρ&lt;/i&gt; = 0.52, &lt;i&gt;p&lt;/i&gt; = 0.001) and negatively correlated with cJLCA (pre-stand to post-stand) (&lt;i&gt;ρ&lt;/i&gt; = −0.43, &lt;i&gt;p&lt;/i&gt; = 0.007). In multivariable analysis, dJLCA remained independently associated with both outcomes (&lt;i&gt;B&lt;/i&gt; = 0.51, &lt;i&gt;p&lt;/i&gt; = 0.006; &lt;i&gt;B&lt;/i&gt; = −0.49, &lt;i&gt;p&lt;/i&gt; = 0.008, respectively).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The preoperative standing-supine difference in JLCA was the primary determinant of postoperative change in JLCA after CWHTO. A greater standing-supine difference was associated with greater undercorrection when supine radiographs were used as the planning reference, but with greater overcorrection when standing radiographs were used as the planning reference.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Level of Evidence&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Level IV.&lt;/p&gt;\u0000 &lt;/s","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward functional integration of 3D-printed meniscal scaffolds: A materials-driven systematic review of preclinical evidence and translational framework","authors":"Andrea Ferrero,&nbsp;Giuseppe Anzillotti,&nbsp;Pietro Conte,&nbsp;Simonetta Resta,&nbsp;Simone Micalizzi,&nbsp;Cecilia Cappelli,&nbsp;Nada Mansour,&nbsp;Paolo Oliva,&nbsp;Elizaveta Kon,&nbsp;Daniele D'Arrigo","doi":"10.1002/jeo2.70898","DOIUrl":"10.1002/jeo2.70898","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Meniscal injuries are among the most common knee disorders and a major risk factor for osteoarthritis. Although meniscectomy provides short-term symptom relief, it irreversibly alters joint biomechanics, underscoring the need for regenerative strategies. Advances in additive manufacturing and biomaterials science have enabled three-dimensional (3D)-printed meniscal scaffolds with controlled architecture, tunable anisotropy and tailored biological functionality. This systematic review critically evaluates preclinical in vivo evidence on these strategies and identifies key factors influencing their functional integration and translational potential.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A systematic literature search was conducted in PubMed, Web of Knowledge and Scopus up to September 2025, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Included studies involved preclinical in vivo models of meniscectomy evaluating 3D-printed meniscal scaffolds with reported mechanical and biological outcomes. Data extraction focused on biomaterials, fabrication techniques, scaffold design, mechanical performance and regenerative outcomes.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Twenty-three studies met the inclusion criteria. Resorbable polymer-based scaffolds, predominantly polycaprolactone, were most frequently investigated. Biofunctionalisation strategies—including cellularisation, biochemical cues and hydrogel–polymer composites—were widely employed. Most studies used rabbit models. Outcomes revealed a dynamic interplay between material composition, architecture, degradation kinetics and biological integration. An initial decline in mechanical properties was followed by progressive maturation, in some cases approaching native anisotropic behaviour and correlating with cellular infiltration and matrix deposition. Biofunctionalised scaffolds consistently demonstrated improved cartilage preservation compared with meniscectomy alone. However, heterogeneity in experimental design and reporting standards limited cross-study comparability.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;3D-printed meniscal scaffolds show promising preclinical potential for promoting tissue regeneration and preserving joint integrity. To bridge the gap between experimental findings and clinical application, this review introduces a structured reporting checklist identifying key material, structural and biological determinants of successful scaffold integration. By promoting methodologi","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative landmarking errors and their avoidance in robotic-assisted total knee arthroplasty using the VELYS system","authors":"Alexander Aichmair,&nbsp;Heiko Graichen,&nbsp;Nimrod Snir,&nbsp;Benjamin V. Bloch,&nbsp;Ugonna N. Ihekweazu,&nbsp;Jochen G. Hofstaetter,&nbsp;Michael T. Hirschmann,&nbsp;Pieter-Jan Vandekerckhove","doi":"10.1002/jeo2.70902","DOIUrl":"10.1002/jeo2.70902","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 <p>While robotic-assisted total knee arthroplasty (rTKA) has been proven to achieve highly precise and reproducible radiographic results, its accuracy remains highly dependent on correct intraoperative landmark acquisition. This technical guide aims to provide practical guidance for intraoperative recognition of landmarking and gap balance assessment errors during rTKA using the image-free VELYS^TM system. Based on the authors' clinical experience with this system, the most common pitfalls as well as their intraoperative recognition are highlighted. Special focus is set on pin placement, bone reference checkpoints and landmark acquisition, with practical intraoperative cues that allow surgeons to detect these errors intraoperatively before bone resections are performed. The present article should support early adopters of the VELYS^TM system, with the aim of preventing precision inaccuracies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level V.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concomitant arthroscopy during valgus-producing high tibial osteotomy does not demonstrate consistent additional clinical benefit despite improved cartilage findings: A systematic review of comparative studies","authors":"Dave Osinachukwu Duru,&nbsp;Ebenezeer Mussie,&nbsp;Taimoor A. Sehgol,&nbsp;Yuta Nakanishi,&nbsp;Ryan M. Degen","doi":"10.1002/jeo2.70903","DOIUrl":"10.1002/jeo2.70903","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To evaluate whether concomitant arthroscopic treatment of intra-articular chondral or meniscal pathology during valgus-producing high tibial osteotomy (HTO) improves clinical outcomes compared with HTO alone.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;MEDLINE, Embase and CENTRAL were searched from inception to 17 May 2026. Comparative studies reporting outcomes after HTO plus arthroscopic cartilage (microfracture, microdrilling, abrasion arthroplasty) and/or meniscal (meniscal centralization, meniscectomy, meniscal repair) procedures versus HTO alone were included. Data extraction and quality assessment were performed by two reviewers. Due to heterogeneity, meta-analysis was not performed, and outcomes were synthesized descriptively, stratified by specific arthroscopic adjunct.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Seventeen studies comprising 1271 knees were included, with 663 treated with HTO plus arthroscopy and 608 treated with HTO alone. The mean age was 57.0 years with HTO plus arthroscopy and 55.1 years with HTO. Mean follow-up was 32.9 months and 31.0 months, respectively. Concomitant procedures were microfracture in six studies, microdrilling in three, abrasion arthroplasty in two, meniscectomy in two, meniscal centralization in two and mixed arthroscopy in four. Both groups generally improved across patient-reported outcome measures (PROMs), functional outcomes and radiographic alignment. However, no arthroscopic adjunct demonstrated consistent additive clinical benefit. Microfracture showed inconsistent effects on Lysholm and Western Ontario and McMaster Universities Osteoarthritis Index scores; meniscectomy did not improve Knee Society Score; and meniscal centralization showed inconsistent Knee injury and Osteoarthritis Outcome Score and alignment findings. Mixed arthroscopy showed some favourable PROMs and radiographic outcomes, but did not isolate procedure-specific effects. Microfracture, microdrilling, abrasion arthroplasty and meniscal centralization improved cartilage findings on second-look arthroscopy, but these improvements did not consistently correspond to superior PROMs. Complication reporting was limited and heterogeneous.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Current evidence does not demonstrate a consistent clinical benefit of adding arthroscopic chondral or meniscal treatment to HTO, despite some evidence of improved cartilage findings. Future procedure-specific comparative studies are needed to determine which, if any, arthroscopic adjuncts provide clinically ","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A long-term comparison of radiographic and clinical outcomes between 62% and 70% weight-bearing line targets in medial opening wedge high tibial osteotomy","authors":"Woon Hwa Jung,&nbsp;Manan Paneliya,&nbsp;Saksham Goyal,&nbsp;Dong Hyun Kim,&nbsp;Ryohei Takeuchi","doi":"10.1002/jeo2.70900","DOIUrl":"10.1002/jeo2.70900","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The ideal intraoperative correction target for medial opening wedge high tibial osteotomy (MOWHTO) remains debated. This study compared 10-year outcomes between two correction targets, 70% and 62% weight-bearing line (WBL).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 103 knees that underwent MOWHTO with a locking plate, performed by one surgeon and randomized to a 70% (<i>n</i> = 50) or 62% (<i>n</i> = 53) WBL target, were retrospectively reviewed. Hip–knee–ankle angle and WBL were measured at fixed time points; clinical scores were recorded at 10 years. Conversion to total knee arthroplasty (TKA) was the primary endpoint. Because Kaplan–Meier curves crossed, a landmark, time-varying analysis was used alongside standard tests.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six-month WBL averaged 71.4% (70% group) and 62.2% (62% group). Both groups lost similar correction by 10 years (−5.5 vs. −4.8 percentage points, <i>p</i> = 0.429), leaving 45% of the 62% group undercorrected versus 13% of the 70% group (<i>p</i> &lt; 0.001). Undercorrected knees were converted to TKA more often than normally aligned knees (36.7% vs. 9.6%, <i>p</i> = 0.012). The proportional hazards assumption was violated for the group effect (<i>p</i> = 0.0025); after 10 years, conditional on event-free survival, the hazard ratio for 70% versus 62% was 0.54 (95% confidence interval 0.245–1.182, <i>p</i> = 0.123). Overall survivorship was similar (22.0% vs. 24.5% converted, <i>p</i> = 0.954), but this comparison was underpowered (4.8%) and should not be read as equivalence. Clinical scores did not differ significantly.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Both targets lost similar correction over 10 years, but the 62% target was closer to the undercorrection range, linked to more TKA conversion. Hazards were not proportional over time: The 70% target carried an early, overcorrection-related risk, while the 62% target carried a later, undercorrection-related risk undetectable by an overall Cox comparison alone. A target close to, but not exceeding, 70% may lower the risk of both patterns, pending confirmation with an intermediate target and a larger, adequately powered sample.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level II, retrospective long-term follow-up analysis of a prospectively randomized cohort.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13528234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Failure rates increase over time and are higher following medial arthroscopic bucket-handle meniscal repair: A systematic review and meta-analysis.","authors":"Amirali Soleymani Nejad, Sohrab Keyhani, Mehran Soleymanha, Fardis Vosoughi, Robert F LaPrade, Maryam Mousavi, Luke V Tollefson","doi":"10.1002/jeo2.70854","DOIUrl":"10.1002/jeo2.70854","url":null,"abstract":"<p><strong>Purpose: </strong>Bucket-handle meniscal tears (BHMTs) constitute a technically demanding form of meniscal injury. However, the incidence of repair failure and the factors influencing outcomes remain incompletely characterised. This study aimed to estimate the pooled failure rate after bucket-handle meniscal repair (BHMR) and to identify variables associated with unsuccessful healing.</p><p><strong>Methods: </strong>A systematic review and meta-analysis (SRMA) was performed to identify studies published from January 2005 through 2026 evaluating arthroscopic BHMR. Eligible designs included randomised trials, cohort studies and case series with at least 15 patients. Random-effects or fixed models were used to calculate pooled failure proportions and odds ratios. Subgroup analyses and meta-regression were conducted to explore potential predictors of failure.</p><p><strong>Results: </strong>The pooled BHMR failure rate was 21.5% (95% CI: 16.3%-27.8%; <i>I</i> ² = 79.2%). Failure rates increased with longer follow-up (<i>β</i> = 0.12, <i>p</i> < 0.01). Medial repairs had significantly higher failure odds than lateral repairs (OR = 2.20, <i>p</i> < 0.001, pooled failure rate: 18.9% vs. 12.1%). No significant differences were observed for tear zone (red-red vs. white-red), sex or isolated (pooled rate: 24.3%) versus concomitant ACLR (pooled rate: 14.9%). Publication bias was suggested by Egger's test (<i>p</i> = 0.02).</p><p><strong>Conclusion: </strong>BHMRs carry a substantial 21.5% failure rate that increases over time, with medial tears at significantly higher risk than lateral tears. Concomitant ACL reconstruction and tear vascularity did not significantly impact failure odds. High-quality prospective studies are needed to optimise patient selection and long-term counselling.</p><p><strong>Level of evidence: </strong>Level II.</p>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":"e70854"},"PeriodicalIF":3.2,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13521520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival of patellofemoral arthroplasty is influenced by patient characteristics, surgical factors and surgeon experience: A systematic review.","authors":"Jean-Marie Philippeau, Franck Rémy, Patrick Le Couteur, Guillaume Demey","doi":"10.1002/jeo2.70868","DOIUrl":"10.1002/jeo2.70868","url":null,"abstract":"<p><strong>Purpose: </strong>While patellofemoral arthroplasty (PFA) offers advantages in preserving the tibiofemoral joint, debate remains regarding ideal patient indications and actual revision rates. The purpose of this systematic review was to identify and critically appraise comparative studies reporting survival of PFA, and to evaluate how variation in key confounding variables influences survival outcomes.</p><p><strong>Methods: </strong>Following PRISMA guidelines and PROSPERO registration, MEDLINE®, EMBASE® and Epistemonikos were searched on 23 February 2026 for comparative studies reporting PFA survival with ≥5-year follow-up. Data extracted included author, cohort size, implant type, follow-up, Kaplan-Meier survival and number at risk. Effective numbers-at-risk and survival probabilities at each event time were reconstructed to estimate the hazard ratio (HR) for revision risk between groups. Risk of bias was assessed using Joanna Briggs Institute checklists.</p><p><strong>Results: </strong>Nine studies were included: seven retrospective clinical cohorts (1071 knees) and two registry studies (9021 knees). Registry survival was 96% at 2 years, 83%-88% at 5-6 years and 73%-76% at 10-11 years (<i>I</i> ², 38.7%). Comparative analyses from clinical studies suggested that several factors, including body mass index (BMI), patellar height, robotic assistance and surgeon experience, may influence revision risk; however, most studies found no statistically significant difference, and some were in disagreement.</p><p><strong>Conclusion: </strong>Survival of PFA ranges from 73% to 76% at 10-11 years, and appears to be influenced by some non-modifiable patient factors (age, BMI and patellar height), and modifiable surgical factors (robotic assistance and surgeon experience). These trends cannot be confirmed because of conflicting findings between eligible studies, which could be due to variability of follow-ups (5-30 years), differences in survival endpoints (any revision or conversion to TKA), as well as the inconsistent thresholds for age and ratios of patellar height.</p><p><strong>Level of evidence: </strong>Level IV.</p>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":"e70868"},"PeriodicalIF":3.2,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13521518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early functional deficits following first-time acute lateral ankle sprain: A multidimensional assessment framework with clinically relevant cut-off values","authors":"Janina Tennler,&nbsp;Christian Raeder,&nbsp;Arthur Praetorius,&nbsp;Sebastian Colcuc,&nbsp;Eva S. Steinhausen,&nbsp;Marcel Dudda,&nbsp;Christian Schoepp","doi":"10.1002/jeo2.70892","DOIUrl":"10.1002/jeo2.70892","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Lateral ankle sprain (LAS) is one of the most common musculoskeletal injuries associated with sensorimotor impairments that increase the risk of reinjury and chronic ankle instability. Early clinical assessment after acute LAS is often symptom-guided rather than based on objective functional testing. This study aimed to identify the most sensitive functional impairments within the first weeks after injury and to determine cut-off values that support structured clinical assessment.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In this cross-sectional matched case-control analysis, 36 individuals (14–41 years) with MRI-confirmed first-time acute LAS were compared to 36 matched healthy controls. Patients (recruiting 01/22-09/24) were assessed 2–3 weeks post-injury using patient-reported outcomes, postural control, strength, range of motion (ROM), gait/running kinematics and jump performance. Between-group differences were analysed using &lt;i&gt;t&lt;/i&gt; tests or Statistical Parametric Mapping. Receiver operating characteristic analyses were used to determine diagnostic cut-off values. It was hypothesized that individuals with acute first-time LAS would demonstrate clinically relevant deficits across functional domains compared with healthy controls, and that these parameters would allow the derivation of clinically useful cut-off values.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Individuals with LAS demonstrated substantial impairments across several domains. The most discriminative parameters were Foot and Ankle Ability Measure (FAAM) Sport (effect size [ES] −4.09, cut-off &lt;86) and Cumberland Ankle Instability Tool (CAIT) (ES −3.65; cut-off &lt;26) (psychometry), Star Excursion Balance Test (SEBT) composite score (ES −1.22; cut-off &lt;92.81) (postural control), concentric plantarflexion strength (ES −1.34; cut-off &lt;2.24 Nm/kg) (strength), passive plantarflexion and total ROM (ES −2.29; cut-off &lt;44° and &lt;72°), transverse ankle kinematics during gait (ES 1.14; cut-off &lt;−15°) (gait/running) and drop jump contact time (ES 1.62; cut-off &gt;0.23 s) (jump performance). These measures formed a minimal multidimensional assessment.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;These parameters and cut-off values enable objective, multidimensional assessment in the early phase after acute LAS and may facilitate impairment-based rehabilitation beyond symptom-guided evaluation.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Level of Evidence&lt;/h3&gt;\u0000 ","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13521570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}