REC: CardioClinics最新文献_第3页

Rol mediador de la gamma-glutamil transferasa en el vínculo entre disfunción ventricular y función sistólica γ -谷氨酰胺转移酶在心室功能障碍与收缩压之间的作用

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-09-16 DOI: 10.1016/j.rccl.2025.08.006

Alberto Guevara Tirado

{"title":"Rol mediador de la gamma-glutamil transferasa en el vínculo entre disfunción ventricular y función sistólica","authors":"Alberto Guevara Tirado","doi":"10.1016/j.rccl.2025.08.006","DOIUrl":"10.1016/j.rccl.2025.08.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Heart failure involves multiorgan dysfunction; the heart–liver axis underlies the concept of the cardiohepatic syndrome. This study evaluated gamma-glutamyl transferase (GGT) as a mediator between left ventricular dysfunction and systolic function.</div></div><div><h3>Methods</h3><div>A cross-sectional analysis was performed using secondary data from 567 patients hospitalized for heart failure. The relationships between left ventricular end-diastolic diameter (LVEDD), GGT, and left ventricular ejection fraction (LVEF) were assessed using Hayes’ PROCESS mediation model 4. Multiple linear regressions were adjusted for comorbidities and clinical variables. The indirect effect was estimated through bootstrap resampling with 5000 iterations. A directed acyclic graph was used to represent the causal hypothesis.</div></div><div><h3>Results</h3><div>A significant association was observed between LVEDD and GGT (<em>B</em>  =−0.021; <em>P</em>=.009), and LVEDD also showed a negative association with LVEF (<em>B</em>  <!-->−2.40; <em>P</em><.001). Mediation analysis revealed a significant indirect effect of LVEDD on LVEF through GGT (−0.11; 95%CI: −0.23 to −0.005), supporting the mediating role of this enzyme in the cardiohepatic axis.</div></div><div><h3>Conclusions</h3><div>GGT may act as a mediator between ventricular dysfunction and reduced LVEF in patients hospitalized with heart failure, reflecting a clinically relevant cardiohepatic interaction.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 24-31"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Características y evolución de la concesión de patentes en el área cardiovascular en España 西班牙心血管领域专利授予的特点和演变

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-09-20 DOI: 10.1016/j.rccl.2025.08.004

Francisco J. Chorro , Adolfo Alonso-Arroyo , Cristina I. Font-Julián , Yiming Liu , Rafael Aleixandre-Benavent

{"title":"Características y evolución de la concesión de patentes en el área cardiovascular en España","authors":"Francisco J. Chorro , Adolfo Alonso-Arroyo , Cristina I. Font-Julián , Yiming Liu , Rafael Aleixandre-Benavent","doi":"10.1016/j.rccl.2025.08.004","DOIUrl":"10.1016/j.rccl.2025.08.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Updated analysis of patent grants related to cardiovascular diseases (CVD) in Spain.</div></div><div><h3>Methods</h3><div>Development of a search process for patents related to CVD in the Global Patent Index, review of those granted in Spain, and standardization. Analysis of their evolution over time, origin, collaborations, types, and thematic distribution.</div></div><div><h3>Results</h3><div>Identification of 1870 patents (1909-2023), whose growth has been exponential (n=1.687 exp [0.066*years; <em>P</em><.001). They come from 1107 applicants from 39 countries, 616 from Spain who have originated 923 patents, followed by Germany (293), Switzerland (177), France (92) and the Netherlands (81). Collaborations are present in 15.2%. Seven networks have involved ≥ 3 applicants with ≥ 2 collaborations. The most frequent subject has been “pharmacological treatments” (38%), and in this group “antihypertensives”. Since 1992, translations of European patents have increased, and are currently the most common type. The proportions by thematic group have varied significantly (<em>P</em><.001), with more recent increases in those related to “catheters/devices” and “diagnostic/monitoring techniques” and decreases in “pharmacological treatments” and “biochemistry/molecular biology”.</div></div><div><h3>Conclusions</h3><div>Patents related to CVD in Spain originate mainly in Europe. 15.2% are requested in collaboration. The highest number corresponds to Spain, followed by Germany, Switzerland, France, and the Netherlands. The most frequent subject has been “antihypertensive treatments”. Overall, the largest increase in grants (close to 40%) occurred in the decade 2010-2020, especially related to the translation of European patents. The subjects that are growing the most in the 21st century are those related to “catheters/devices” and “diagnostic/monitoring techniques”.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 41-56"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Purulent pericarditis in the 21st century. Causes, clinical presentation, and prognostic factors at a referral center 21世纪的化脓性心包炎。病因、临床表现和转诊中心的预后因素

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-02-21 DOI: 10.1016/j.rccl.2025.02.001

Maria Calvo-Barceló , Maria Vidal-Burdeus , José A. Barrabés , Ignacio Ferreira-González , Núria Fernández-Hidalgo , Pau Rello

引用次数: 0

Desenmascarando el gradiente oculto: el papel de la ecocardiografía de esfuerzo en la miocardiopatía hipertrófica 揭开隐藏的梯度：用力超声心动图在肥厚性心肌病中的作用

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-10-29 DOI: 10.1016/j.rccl.2025.10.004

Noemí Ramos López , Jesús González Mirelis , Esther González-López

引用次数: 0

Embolia paradójica inminente por foramen oval permeable 可穿孔的椭圆形孔即将形成矛盾栓塞

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-08-12 DOI: 10.1016/j.rccl.2025.07.003

Juan Manuel Serrano-Marcos, Miguel Morales-García, Juan Emilio Alcalá-López

引用次数: 0

Utilidad del ecocardiograma de esfuerzo en la valoración de pacientes con miocardiopatía hipertrófica 超声心动图在评估肥厚性心肌病患者中的作用

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-08-12 DOI: 10.1016/j.rccl.2025.07.006

Juan Geraldo-Martínez , Alba Corralejo-del-Peso , Virginia Ruiz-Pizarro , Marta Alamar-Cervera , Jorge Álvarez-Rubio , Joan Torres-Marqués , Esther Moranta-Ribas , David Crémer-Luengos , Carlos Veras-Burgos , María Monserrat-Companys , Tomás Ripoll-Vera

{"title":"Utilidad del ecocardiograma de esfuerzo en la valoración de pacientes con miocardiopatía hipertrófica","authors":"Juan Geraldo-Martínez , Alba Corralejo-del-Peso , Virginia Ruiz-Pizarro , Marta Alamar-Cervera , Jorge Álvarez-Rubio , Joan Torres-Marqués , Esther Moranta-Ribas , David Crémer-Luengos , Carlos Veras-Burgos , María Monserrat-Companys , Tomás Ripoll-Vera","doi":"10.1016/j.rccl.2025.07.006","DOIUrl":"10.1016/j.rccl.2025.07.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>One-third of patients with hypertrophic cardiomyopathy (HCM) present left ventricular outflow tract obstruction at rest. However, a significant percentage of patients show latent obstruction. Exercise echocardiography is valuable for detecting this hidden gradient. The aim of this study is to analyze predictors of latent left ventricular outflow tract obstruction and its prognostic implications.</div></div><div><h3>Methods</h3><div>We conducted a single-center retrospective study in 150 patients diagnosed with HCM according to European Society of Cardiology criteria, all of whom underwent exercise echocardiography. Demographic, clinical, echocardiographic, and long-term adverse event data were collected. Characteristics of patients with and without latent obstruction were compared, and prognostic factors associated with severe events were examined.</div></div><div><h3>Results</h3><div>Resting obstruction was present in 9% of the cohort, while 24% exhibited latent obstruction. Absence of atrial fibrillation, the use of beta-blockers or disopyramide, and an elevated baseline or post-Valsalva gradient were associated with latent obstruction. Neither latent obstruction nor gradient magnitude correlated with adverse events. Worse prognosis was linked to older age, increased ventricular wall thickness, New York Heart Association functional classIII orIV, and use of beta-blockers or disopyramide.</div></div><div><h3>Conclusions</h3><div>Exercise echocardiography is a safe and useful method for detecting latent obstruction in HCM patients. Although the induced gradient did not correlate with prognosis, identifying it could enhance overall patient assessment.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 16-23"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aislamiento de venas pulmonares en fibrilación auricular paroxística y persistente. Electroporación o radiofrecuencia 在突发和持续性耳纤颤中肺静脉的隔离。电或射频

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-06-24 DOI: 10.1016/j.rccl.2025.06.002

Joaquín Osca Asensi , Josep Navarro-Manchón , María Teresa Izquierdo de Francisco , Óscar Cano Pérez , Javier Navarrete Navarro , Carmen Arveras Martínez , Francisco Javier Chorro Gascó , Luis Martínez-Dolz

{"title":"Aislamiento de venas pulmonares en fibrilación auricular paroxística y persistente. Electroporación o radiofrecuencia","authors":"Joaquín Osca Asensi , Josep Navarro-Manchón , María Teresa Izquierdo de Francisco , Óscar Cano Pérez , Javier Navarrete Navarro , Carmen Arveras Martínez , Francisco Javier Chorro Gascó , Luis Martínez-Dolz","doi":"10.1016/j.rccl.2025.06.002","DOIUrl":"10.1016/j.rccl.2025.06.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Pulsed-field ablation (PFA) has emerged as an alternative to radiofrequency and cryoablation for pulmonary vein isolation (PVI). The effectiveness and safety of PFA versus radiofrequency for PVI is not sufficiently studied.</div></div><div><h3>Methods</h3><div>Unicentric and retrospective study. Consecutive patients with paroxysmal or persistent atrial fibrillation undergoing PVI with PFA or radiofrequency in 2 historical cohorts were included. The primary outcome was recurrence of any atrial arrhythmia after a 90-day blanking period. Patients underwent usual clinical follow-up.</div></div><div><h3>Results</h3><div>A total of 374 patients were remitted to PVI (198 to PFA and 176 to radiofrequency). At 1 year 82,3% were free of auricular arrhythmias in PFA versus 82,4% in radiofrequency (<em>P</em>   =.001). However, fluoroscopy time was significantly longer in PFA (13 vs 5minutes; <em>P</em>  =.0001).</div></div><div><h3>Conclusions</h3><div>PFA compared with radiofrequency PVI shows a similar procedural effectiveness but is associated with shorter procedure time and longer fluoroscopy. Organized atrial arrhythmias after PVI were similar.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 7-15"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

El papel del ejercicio físico en la salud cardiovascular de la mujer. Documento de posicionamiento de SEC-Asociación de Cardiología Preventiva/SEC-GT Ejercicio Físico y Salud Cardiovascular 体育锻炼在妇女心血管健康中的作用。美国证券交易委员会-预防心脏病学会/美国证券交易委员会-GT -体育锻炼与心血管健康立场文件

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-11-28 DOI: 10.1016/j.rccl.2025.10.005

María Dolores Masiá Mondéjar , Isabel López-Ruiz , Juan Quiles , Lara Sánchez Suárez , Olivia Rubio Sanz , Javier Roibal Pravio , Rocío Álvarez Bernabéu , Maia Brik , Manuel Gallando Brejano , Juan Ramón Heredia-Elvar , Araceli Boraita

{"title":"El papel del ejercicio físico en la salud cardiovascular de la mujer. Documento de posicionamiento de SEC-Asociación de Cardiología Preventiva/SEC-GT Ejercicio Físico y Salud Cardiovascular","authors":"María Dolores Masiá Mondéjar , Isabel López-Ruiz , Juan Quiles , Lara Sánchez Suárez , Olivia Rubio Sanz , Javier Roibal Pravio , Rocío Álvarez Bernabéu , Maia Brik , Manuel Gallando Brejano , Juan Ramón Heredia-Elvar , Araceli Boraita","doi":"10.1016/j.rccl.2025.10.005","DOIUrl":"10.1016/j.rccl.2025.10.005","url":null,"abstract":"<div><div>Cardiovascular disease remains the leading cause of death in women worldwide. Ischemic heart disease and stroke are responsible for more than 8million deaths per year in this population. The practice of physical exercise is associated with multiple benefits for women's health and fitness, across the lifespan. These benefits are strongly supported by scientific evidence: physical exercise can prevent and treat numerous noncommunicable diseases, including cardiovascular disease. Therefore, the aim of this position statement document, endorsed by the Working Group on Physical Exercise and Cardiovascular Health, the strategic project Woman and Heart, and the Association of Preventive Cardiology of the Spanish Society of Cardiology (SEC), was to review the scientific and practical knowledge regarding exercise interventions in women's cardiovascular health, in order to establish solid and rigorous criteria for health professionals. This document provides the necessary tools to design training programs for this population that ensure individualized prescription according to each woman's specific needs.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 57-67"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conexión auriculoventricular discordante con atresia pulmonar 心室耳连接不协调与肺闭锁

REC: CardioClinics Pub Date : 2026-01-01 Epub Date: 2025-09-05 DOI: 10.1016/j.rccl.2025.07.005

Diana Isabel Katekaru-Tokeshi , Karen Pamela Alvitres-Oré , Moisés Jiménez-Santos , Eric Kimura-Hayama

引用次数: 0

Determinantes e impacto de la mala calidad del sueño en los pacientes hospitalizados por problemas cardiológicos 睡眠质量差对心脏病住院患者的决定因素和影响

REC: CardioClinics Pub Date : 2025-10-01 Epub Date: 2025-06-24 DOI: 10.1016/j.rccl.2025.05.001

Raúl Gascueña , Carlos de Blas , Carlos Carrasco , Julia Gómez , Rocío Ruesgas , Juan Manuel Grande

{"title":"Determinantes e impacto de la mala calidad del sueño en los pacientes hospitalizados por problemas cardiológicos","authors":"Raúl Gascueña , Carlos de Blas , Carlos Carrasco , Julia Gómez , Rocío Ruesgas , Juan Manuel Grande","doi":"10.1016/j.rccl.2025.05.001","DOIUrl":"10.1016/j.rccl.2025.05.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>To evaluate the prevalence and consequences of sleep disorders in hospitalized cardiology patients and identify clinical and psychosocial predictors in order to improve their detection and subsequent management.</div></div><div><h3>Methods</h3><div>Anxiety and depression (HADS scale), quality of life (SF-12 questionnaire) and sleep quality (Pittsburgh Sleep Quality Index [PSQI]) were evaluated in consecutive cardiological hospitalized patients. The duration of hospitalization and events during the year following admission were prospectively collected.</div></div><div><h3>Results</h3><div>A total of 100 consecutive patients were included (58% male, median age 74.4 years). 77% had poor sleep quality (PSQI>5), a lower physical SF-12 score (Δ 5.75; 95%CI, 1.0-10.5; <em>P</em>  =.032) and more non-cardiological emergencies (adjusted HR, 3.24; 95%CI, 1.09-6.66; <em>P</em>     </em>=.012) and anxiety (OR, 1,3; 95%CI, 1.1-1.6; <em>P</em>  <!-->.001).</div></div><div><h3>Conclusions</h3><div>Poor sleep quality is very prevalent in cardiological hospitalized patients. It decreases physical quality of life, prolongs hospitalization and predicts more visits to the emergency department. Its predictors are anxiety and previous antidepressant treatment, and it is associated with a lower income level and an uncomfortable home.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"60 4","pages":"Pages 253-262"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145340518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0