REC: CardioClinics最新文献

{"title":"cHDL reevaluado: nuevos conocimientos y nuevo potencial en la farmacología cardiovascular","authors":"Rosa Fernández-Olmo ,&nbsp;Alberto Cordero ,&nbsp;Olga González Albarrán ,&nbsp;José López Miranda ,&nbsp;Lina Badimón","doi":"10.1016/j.rccl.2025.12.004","DOIUrl":"10.1016/j.rccl.2025.12.004","url":null,"abstract":"<div><div>High-density lipoproteins (HDL) have traditionally been considered protective against atherosclerotic vascular disease (VAD) due to their role in reverse cholesterol transport. However, recent studies have questioned the clinical utility of plasma levels of HDL-cholesterol (HDL-C), highlighting the importance of their functionality beyond their quantity. Accumulating evidence suggests that properties such as its antioxidant, anti-inflammatory, and cholesterol-efflux capacity could be better indicators of its anti-atherogenic potential. Despite the advances, multiple clinical trials aimed at raising HDL-C have failed to reduce cardiovascular events, highlighting the need for a focused approach to improving HDL functional quality. In this context, new treatments such as Obicetrapib, a cholesteryl ester transfer protein inhibitor, have shown promising effects by improving the lipid profile and cholesterol efflux without compromising safety, proposing a more effective and global strategy for the management of VAD. This article critically reviews the evolution of knowledge about HDL, underlines the relevance of evaluating its functionality as a biomarker, and explores future therapeutic strategies based on this approach.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 2","pages":"Pages 137-146"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influencia del sexo femenino en la incidencia y el pronóstico de la insuficiencia cardiaca y fracción de eyección mejorada","authors":"Paula Gramage Sanchis,&nbsp;Celia Gil Llopis,&nbsp;Alberto Hidalgo Mateos,&nbsp;Juan Geraldo Martínez,&nbsp;Ester Galiana Talavera,&nbsp;Guillermo García Martín,&nbsp;Alejandro Queipo Rodríguez,&nbsp;Vicente Mora Llabata,&nbsp;Ildefonso Roldán Torres,&nbsp;Amparo Valls Serral","doi":"10.1016/j.rccl.2025.09.001","DOIUrl":"10.1016/j.rccl.2025.09.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Heart failure (HF) with improved left ventricular ejection fraction (HFimpEF) is a recently defined clinical entity. Data regarding its natural history is still limited. We evaluated the effect of female sex on the incidence and prognosis of patients with HFimpEF.</div></div><div><h3>Methods</h3><div>Retrospective study of a cohort of patients with HF and reduced ejection fraction. HFimpEF was defined as an increase of ≥<!--> <!-->10 percentage points in left ventricular ejection from baseline with a final value &gt;<!--> <!-->40%, measured at least 3<!--> <!-->months after discharge. The primary objective was the incidence of HFimpEF; the secondary was the combined event of cardiovascular death and HF hospitalization. We estimated the predictors of HFimpEF and their relationship with events, stratified by sex.</div></div><div><h3>Results</h3><div>A total of 270 patients (mean age: 66.3<!--> <!-->±<!--> <!-->11.5 years; 30.4% women) were included. HFimpEF occurred in 105 cases (38.9%) and was more frequent in women (43.8% vs 21.8%; <em>P</em> <!-->&lt;<!--> <!-->.001). These patients had a lower prevalence of ischemic etiology (11.3% vs 53.3%; <em>P</em> <!-->&lt;<!--> <!-->.001), dyslipidemia (49.5% vs 64.8%; <em>P</em> <!-->=<!--> <!-->.013), and hypertension (57.1% vs 73.3%; <em>P</em> <!-->=<!--> <!-->.006), and higher rates of optimal medical therapy (58.1% vs 45.8%; <em>P</em> <!-->=<!--> <!-->.009). There were no differences in indexed ventricular volumes between sexes. Female sex was an independent predictor of HFimpEF, adjusted OR, 2.28; 95%CI, 1.25-4.15; <em>P</em> <!-->=<!--> <!-->.007. HFimpEF was associated with a lower probability of the combined event (21.9% vs 49.7%; log-rank <em>P</em> <!-->&lt;<!--> <!-->.001), and age was the only predictor of the combined event.</div></div><div><h3>Conclusions</h3><div>HFimpEF represents a distinct phenotype. Female sex predicts left ventricular ejection recovery but not cardiovascular events, where age was the only predictor.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 2","pages":"Pages 109-119"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147726967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rehabilitación cardiaca en el paciente mayor, un reto necesario","authors":"Regina Dalmau González-Gallarza,&nbsp;Cristina Contreras Lorenzo","doi":"10.1016/j.rccl.2025.12.002","DOIUrl":"10.1016/j.rccl.2025.12.002","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 2","pages":"Pages 81-83"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147726971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Junta Directiva y Comité Organizador - Científico","authors":"","doi":"10.1016/S2605-1532(26)00013-0","DOIUrl":"10.1016/S2605-1532(26)00013-0","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 ","pages":"Page I"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147555617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presentación","authors":"","doi":"10.1016/S2605-1532(26)00014-2","DOIUrl":"10.1016/S2605-1532(26)00014-2","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 ","pages":"Page S1"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147555618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Índice de autores","authors":"","doi":"10.1016/S2605-1532(26)00016-6","DOIUrl":"10.1016/S2605-1532(26)00016-6","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 ","pages":"Pages S13-S14"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147555620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comunicaciones","authors":"","doi":"10.1016/S2605-1532(26)00015-4","DOIUrl":"10.1016/S2605-1532(26)00015-4","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 ","pages":"Pages S2-S12"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147555619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementación de un algoritmo diagnóstico-terapéutico para hipoflujo pulmonar tras cirugía de fístula sistémico-pulmonar","authors":"Amaranta López-Santiago ,&nbsp;Antonio Juanico-Enríquez ,&nbsp;Theo Y. Contreras-Alvarado ,&nbsp;Kenneth G.A. Magaña ,&nbsp;Yuriria E. Olivares-Fernández ,&nbsp;Jocelyn Castro-Pineda ,&nbsp;Martín A. Saldaña-Becerra ,&nbsp;Chantale Gilles-Herrera ,&nbsp;Carlos Zabal-Cerdeira ,&nbsp;Sofía de la Cruz-Pérez ,&nbsp;Joan S. Celis-Jasso","doi":"10.1016/j.rccl.2025.08.002","DOIUrl":"10.1016/j.rccl.2025.08.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The systemic-to-pulmonary shunt (SPS) is a high-risk procedure with significant mortality in developing countries.</div></div><div><h3>Methods</h3><div>A retrospective, observational and analytical multicenter study was conducted. Medical records of patients with congenital heart disease who underwent SPS surgery between January 2016 and December 2020 were reviewed. Two high-specialty cardiology centers participated, and patients were divided into 2 groups (control group vs. algorithm group).</div></div><div><h3>Results</h3><div>A total of 94 patients were identified: 47 in the control group and 47 in the algorithm group. Emergency surgery was required in 35.1% of cases. The most common SPS size was 4<!--> <!-->mm. Thrombosis and shunt reintervention were more frequent in the control group (23.4 vs. 2.1%; <em>P</em> <!-->&lt;<!--> <!-->.001; 10.6 vs. 2.1%; <em>P</em> <!-->&lt;<!--> <!-->.164). A reduced risk was observed for postoperative desaturation (oxygen saturation<!--> <!-->&lt;<!--> <!-->75%) (OR, 0.16; 95%CI 0.03-0.54; <em>P</em> <!-->=<!--> <!-->.006), thrombosis (OR, 0.07; 95%CI 0.00-0.39; <em>P</em> <!-->=<!--> <!-->.013), emergency postoperative surgery (OR, 0.16; 95%CI 0.03-0.54; <em>P</em> <!-->=<!--> <!-->.006), length of stay in the intensive care unit (mean<!--> <!-->=<!--> <!-->3-9 days, OR, 0.38; 95%CI 0.15-0.90; <em>P</em> <!-->=<!--> <!-->.032), and mortality (OR, 0.31; 95%CI 0.11-0.81; <em>P</em> <!-->=<!--> <!-->.021) in the algorithm group.</div></div><div><h3>Conclusions</h3><div>The resulting algorithm provides valuable information for the early identification of pulmonary hypoperfusion. The initiation and maintenance of appropriate medical approach lead to improved clinical outcomes and reduced mortality in these patients.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 32-40"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La electroporación en la vida real, ¿solo cuestión de tiempo?","authors":"Concepción Alonso-Martín ,&nbsp;Bieito Campos García ,&nbsp;Francisco Javier Méndez Zurita","doi":"10.1016/j.rccl.2025.08.003","DOIUrl":"10.1016/j.rccl.2025.08.003","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 1-3"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of complications in pregnant patients with cardiac implantable electronic devices","authors":"Javier Cantalapiedra-Romero ,&nbsp;Laura Galian-Gay ,&nbsp;Jaume Francisco-Pascual ,&nbsp;Berta Serrano-Sánchez ,&nbsp;Nerea Maíz ,&nbsp;Antònia Pijuan-Domènech","doi":"10.1016/j.rccl.2025.01.009","DOIUrl":"10.1016/j.rccl.2025.01.009","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 1","pages":"Pages 68-71"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}