REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-03-31DOI: 10.1016/j.rccl.2026.02.003
Albert Ariza-Solé, Chaima Zoljami Aidoun
{"title":"Predictors of sudden cardiac arrest in vasospastic angina","authors":"Albert Ariza-Solé, Chaima Zoljami Aidoun","doi":"10.1016/j.rccl.2026.02.003","DOIUrl":"10.1016/j.rccl.2026.02.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Vasospastic angina (VSA) is a type of angina caused by spontaneous coronary spasms, which can result in ischemic episodes with serious complications such as sudden cardiac arrest (SCA). Although these events may be considered rare in the context of VSA, they are not uncommon and might be life-threatening. The primary objective of this study is to identify potential predictive factors of SCA in patients admitted for VSA.</div></div><div><h3>Methods</h3><div>A retrospective observational study was conducted at Bellvitge University Hospital in Catalonia. A total of 150 patients diagnosed with VSA between January 2010 and February 2022 were included. The primary endpoint was the occurrence of SCA during the follow-up period. The cohort was stratified into 2 groups to assess differences between patients who experienced SCA and those who did not.</div></div><div><h3>Results</h3><div>At the end of the follow-up, 10 patients suffered an SCA (6.67%). The final multivariant model showed that a higher likelihood of SCA was associated with chest pain at rest, cocaine consumption, and a low left ventricular ejection fraction. The model's area under the curve was 0.872. The mortality rate in patients with SCA was 30%.</div></div><div><h3>Conclusions</h3><div>Although uncommon, episodes of SCA in patients with VSA are not infrequent and carry a significant mortality rate. These events are more likely to occur in patients with cocaine consumption, those experiencing chest pain at rest, and those with a lower ejection fraction during their initial admission for VSA.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 275-282"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-06-26DOI: 10.1016/j.rccl.2026.06.001
Marta Cobo Marcos
{"title":"Bridging the gap between clinician assessment and patient experience in heart failure","authors":"Marta Cobo Marcos","doi":"10.1016/j.rccl.2026.06.001","DOIUrl":"10.1016/j.rccl.2026.06.001","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 266-267"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-04-10DOI: 10.1016/j.rccl.2026.03.002
María G. Crespo-Leiro, Beatriz Díaz-Molina, José M. García-Pinilla, Josebe Goirigolzarri-Artaza, Ainara Lozano-Bahamonde, Julio Núñez, María J. Movilla-Fernández, Paula Blanco-Canosa, Zulaica Grille-Cancela, Theresa McDonagh, Javier Muñiz
{"title":"Health outcomes reported by patients with heart failure: HF-OUTCOMES-Spain study","authors":"María G. Crespo-Leiro, Beatriz Díaz-Molina, José M. García-Pinilla, Josebe Goirigolzarri-Artaza, Ainara Lozano-Bahamonde, Julio Núñez, María J. Movilla-Fernández, Paula Blanco-Canosa, Zulaica Grille-Cancela, Theresa McDonagh, Javier Muñiz","doi":"10.1016/j.rccl.2026.03.002","DOIUrl":"10.1016/j.rccl.2026.03.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The feasibility of application and usefulness in daily clinical practice of the International Consortium for Health Outcomes Measurement-Heart Failure (ICHOM-HF) set is unknown. The objective of this study was to evaluate the feasibility of implementation and compliance at one year of the ICHOM-HF set in Spanish public hospitals after an episode of heart failure or a scheduled outpatient visit for HF.</div></div><div><h3>Methods</h3><div>HF-OUTCOMES-Spain is a longitudinal study of patients with HF recruited from the cardiology departments of 6 hospitals followed up according to adapted ICHOM-HF recommendations. Success was defined as the proportion of follow-up visits performed as planned >70% and the proportion of missing data <10%.</div></div><div><h3>Results</h3><div>A total of 581 consecutive patients (mean age 68.8 years, 36% women) participated, 73 after hospitalization and 508 as outpatients. A total of 97.3% (248/255) of visits were performed at 30 days according to protocol, as were 97% (532/548) at 6 months and 95.4% (473/496) at 1 year. The results reported by physicians met the target of <10% missing data, while some patient reported outcome measures fell just short, with significant differences between hospitals. Patient reported outcome measures detected common conditions that would otherwise go unnoticed (e.g., suspected depression). Women reported more symptoms, poorer functional status, and more disease-related limitations than men.</div></div><div><h3>Conclusions</h3><div>Implementing the ICHOM-HF set in Spanish public hospitals is feasible and can help identify patients with special treatment needs. (ClinicalTrials.gov: <span><span>NCT04806048</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 283-295"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-01-12DOI: 10.1016/j.rccl.2025.12.006
Ester Mínguez de la Guía, Macarena López Vázquez, Julia Piñana Sendra, María Isabel Barrionuevo Sánchez, Francisco Manuel Salmerón Martínez, Miguel José Corbí Pascual
{"title":"Impact of standardized protocol following cardiac arrest with targeted temperature management on neurological outcomes","authors":"Ester Mínguez de la Guía, Macarena López Vázquez, Julia Piñana Sendra, María Isabel Barrionuevo Sánchez, Francisco Manuel Salmerón Martínez, Miguel José Corbí Pascual","doi":"10.1016/j.rccl.2025.12.006","DOIUrl":"10.1016/j.rccl.2025.12.006","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 317-320"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-07-01Epub Date: 2025-11-26DOI: 10.1016/j.rccl.2025.10.007
Carla Oliveira Ferreira, Eduarda Silva, Filipe Silva Vilela, Sofia Nogueira Fernandes, Mónica Dias, Inês Macedo Conde, Bárbara Rocha, João Faria, Carlos Galvão Braga, Cátia Costa Oliveira
{"title":"Association between functional class and functional capacity measured by exercise stress test in patients with HFrEF","authors":"Carla Oliveira Ferreira, Eduarda Silva, Filipe Silva Vilela, Sofia Nogueira Fernandes, Mónica Dias, Inês Macedo Conde, Bárbara Rocha, João Faria, Carlos Galvão Braga, Cátia Costa Oliveira","doi":"10.1016/j.rccl.2025.10.007","DOIUrl":"10.1016/j.rccl.2025.10.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The New York Heart Association (NYHA) classification is widely used in clinical practice, the clinical and prognostic assessment of patients with heart failure. However, it remains a subjective classification. On the other hand, the exercise stress test is an accessible complementary examination that allows a more objective evaluation of a patient's functional capacity. The aim of this study was to analyze the association between physician-perceived NYHA classification and exercise capacity measured by an exercise test.</div></div><div><h3>Methods</h3><div>This was an observational, analytical and retrospective study that included 300 patients with heart failure and left ventricular ejection fraction <50% who underwent an exercise test between January 2018 and December 2022.</div></div><div><h3>Results</h3><div>The majority of patients were classified as NYHA functional class I (59.3%). The association between NYHA classes and functional capacity was 0.280 (<em>P</em> <!--><<!--> <!-->.001). NYHA class was associated with functional capacity, explaining 14.0% of the variation in METs (partial eta<sup>2</sup> <!-->=<!--> <!-->0.140, <em>P</em> <!--><<!--> <!-->.001). Adjusted mean METs were 7.77 (7.44–8.10) for NYHA I, 6.18 (5.76–6.59) for NYHA II, and 4.78 (3.52–6.04) for NYHA III. No association was found between NYHA classes and median N-terminal pro-B-type natriuretic peptide levels (<em>P</em> <!-->=<!--> <!-->.192) or heart rate recovery (<em>P</em> <!-->=<!--> <!-->.260).</div></div><div><h3>Conclusions</h3><div>NYHA classification was independently associated with exercise capacity. The association was modest, explaining only 14% of the variability. There was no significant association between NYHA classification and prognostic markers in heart failure, namely N-terminal pro-B-type natriuretic peptide and heart rate recovery.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 3","pages":"Pages 177-187"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-07-01Epub Date: 2026-05-19DOI: 10.1016/j.rccl.2026.04.001
José González-Costello, Tomás Ripoll-Vera, Rocío Eiros, Pau Llàcer, Ainara Lozano-Bahamonde, Maria Luisa Peña-Peña, Enrique Santas, Sergi Yun
{"title":"Amiloidosis cardiaca por transtirretina: una revisión de los tratamientos actuales y de las perspectivas futuras","authors":"José González-Costello, Tomás Ripoll-Vera, Rocío Eiros, Pau Llàcer, Ainara Lozano-Bahamonde, Maria Luisa Peña-Peña, Enrique Santas, Sergi Yun","doi":"10.1016/j.rccl.2026.04.001","DOIUrl":"10.1016/j.rccl.2026.04.001","url":null,"abstract":"<div><div>Transthyretin amyloidosis (ATTR) is a progressive and potentially fatal systemic disease caused by the extracellular accumulation of amyloid fibrils derived from transthyretin (TTR). Transthyretin cardiac amyloidosis (ATTR-CA), one of its main manifestations, leads to signs and symptoms of heart failure. Although traditionally an underdiagnosed disease, the availability of non-invasive diagnostic techniques has led to a substantial increase in the number of patients diagnosed with ATTR-CA. In turn, the availability of effective treatments with survival benefits has improved the prognosis for these patients. In this review, we address relevant aspects of the aetiopathogenesis of ATTR-CA, patient screening and diagnosis, as well as the therapeutic options currently available (disease-modifying treatments: tafamidis, acoramidis and vutrisiran) and under development.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 3","pages":"Pages 231-246"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148559847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-07-01Epub Date: 2026-04-01DOI: 10.1016/j.rccl.2026.03.001
Juan Cosín-Sales, Raquel Campuzano Ruiz, Luis Castilla-Guerra, David Vivas, Vivencio Barrios Alonso, Luis Javier Doncel Vecino, Abel García del Egido, Nuria Muñoz-Rivas, Patricia Palau Sampio, Pablo Jorge Pérez, Sergio Raposeiras-Roubín, Irene Rilo Miranda, Román Freixa-Pamias, Juan Ramón Siles Rubio, Juan José Tamarit García, Pablo Antonio Toledo Frías, Vicente Pallarés-Carratalá
{"title":"Delphi expert document on therapeutic adherence in patients with cardiovascular disease: Barriers, facilitators, and clinical implications","authors":"Juan Cosín-Sales, Raquel Campuzano Ruiz, Luis Castilla-Guerra, David Vivas, Vivencio Barrios Alonso, Luis Javier Doncel Vecino, Abel García del Egido, Nuria Muñoz-Rivas, Patricia Palau Sampio, Pablo Jorge Pérez, Sergio Raposeiras-Roubín, Irene Rilo Miranda, Román Freixa-Pamias, Juan Ramón Siles Rubio, Juan José Tamarit García, Pablo Antonio Toledo Frías, Vicente Pallarés-Carratalá","doi":"10.1016/j.rccl.2026.03.001","DOIUrl":"10.1016/j.rccl.2026.03.001","url":null,"abstract":"<div><div>Medication adherence is a key factor in managing cardiovascular disease, as it directly influences clinical control, event prevention, and healthcare efficiency. This Delphi expert involving 118 experts in cardiology, internal medicine, and primary care, aimed to identify barriers, facilitators, and practical strategies to improve adherence in Spain. Fifty statements were evaluated in 2 rounds, followed by 15 local meetings with clinical experts to contextualize and interpret the conclusions. Consensus was reached on 49 statements (98.0%), emphasizing the need to measure and promote adherence systematically. The main barriers identified were polypharmacy, lack of care coordination, and medication costs, while strategies such as fixed-dose combinations, digital tools, health education and patient education were highlighted as key facilitators good adherence was acknowledged to reduce cardiovascular events, hospitalizations, and costs, improving patient quality of life. This document offers clinical and organizational recommendations to optimize therapeutic adherence in cardiovascular patients.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 3","pages":"Pages 217-230"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148559896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-07-01Epub Date: 2026-01-06DOI: 10.1016/j.rccl.2025.12.003
Antonio García-Quintana, Marta López Pérez, Victoria Piro Mastracchio
{"title":"Citisina para la deshabituación tabáquica en pacientes con enfermedad cardiovascular. ¿Humo o realidad?","authors":"Antonio García-Quintana, Marta López Pérez, Victoria Piro Mastracchio","doi":"10.1016/j.rccl.2025.12.003","DOIUrl":"10.1016/j.rccl.2025.12.003","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 3","pages":"Pages 163-165"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-07-01Epub Date: 2025-12-02DOI: 10.1016/j.rccl.2025.10.009
Roshan Kumar Mahat, Suchismita Panda, Gautam Panda
{"title":"Direct versus calculated LDL cholesterol: Insights from the Friedewald, Martin–Hopkins, and Sampson approaches in the Indian population","authors":"Roshan Kumar Mahat, Suchismita Panda, Gautam Panda","doi":"10.1016/j.rccl.2025.10.009","DOIUrl":"10.1016/j.rccl.2025.10.009","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Low-density lipoprotein cholesterol (LDL-C) is a crucial biomarker for cardiovascular disease (CVD) risk assessment and management. Direct LDL-C measurement (D-LDL-C) is preferred but not always feasible, necessitating the use of estimation formulas. The Friedewald equation is the most widely used but is less reliable in cases of high triglycerides (TG). The Martin–Hopkins and Sampson equations offer improved accuracy, yet their performance in the Indian population remains underexplored. This study evaluates and compares these formulas against D-LDL-C in an Indian cohort.</div></div><div><h3>Methods</h3><div>A retrospective study was conducted on 4368 lipid profile samples collected between 2019 and 2024 at a tertiary care center in India. LDL-C was estimated using the Friedewald, Martin–Hopkins, and Sampson equations and compared with D-LDL-C across TG categories: <100<!--> <!-->mg/dL, 100–199<!--> <!-->mg/dL, 200–299<!--> <!-->mg/dL, 300–399<!--> <!-->mg/dL and ≥400<!--> <!-->mg/dL. Agreement and accuracy were evaluated using Pearson correlation, Lin's concordance correlation coefficient (CCC), and Bland–Altman plots.</div></div><div><h3>Results</h3><div>The Martin–Hopkins equation demonstrated the best concordance with D-LDL-C (CCC<!--> <!-->=<!--> <!-->0.9121; mean bias<!--> <!-->=<!--> <!-->−5.37<!--> <!-->mg/dL), followed by the Sampson (CCC<!--> <!-->=<!--> <!-->0.8710; bias<!--> <!-->=<!--> <!-->−11.61<!--> <!-->mg/dL) and Friedewald (CCC<!--> <!-->=<!--> <!-->0.7914; bias<!--> <!-->=<!--> <!-->−18.3<!--> <!-->mg/dL) formulas. Across TG categories, Sampson performed best in low TG (<200<!--> <!-->mg/dL; CCC<!--> <!-->=<!--> <!-->0.9442), but the Martin–Hopkins formula consistently demonstrated superior accuracy and the narrowest limits of agreement in TG ≥200<!--> <!-->mg/dL. At very-high TG (≥800<!--> <!-->mg/dL), Martin–Hopkins nearly matched D-LDL-C bias<!--> <!-->=<!--> <!-->0.32<!--> <!-->mg/dL; <em>P</em> <!-->=<!--> <!-->.674), while both Sampson and Friedewald showed significant underestimation.</div></div><div><h3>Conclusions</h3><div>The Martin–Hopkins equation outperforms the Friedewald and Sampson formulas for LDL-C estimation in the Indian population, especially in patients with elevated TG levels. Adoption of the Martin–Hopkins equation may improve cardiovascular disease risk stratification and guide more accurate therapeutic decisions in clinical practice.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 3","pages":"Pages 197-206"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148559897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}