REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-05-07DOI: 10.1016/j.rccl.2026.04.002
Juan Manuel Serrano-Marcos, José Vico-Jiménez, Juan Emilio Alcalá-López, Rocío García-Orta
{"title":"Túnel aortoventricular como causa excepcional de insuficiencia cardiaca","authors":"Juan Manuel Serrano-Marcos, José Vico-Jiménez, Juan Emilio Alcalá-López, Rocío García-Orta","doi":"10.1016/j.rccl.2026.04.002","DOIUrl":"10.1016/j.rccl.2026.04.002","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 326-327"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-01-20DOI: 10.1016/j.rccl.2025.12.007
Ana Sofia Nogueira Fernandes, Mónica Patrícia Silva Dias, Inês Da Cunha Macedo Conde, Filipe Xavier Silva Vilela, Carla Rafaela Oliveira Ferreira, Jorge Manuel Gomes Sousa Marques, Sérgia Andreia Alves Rodrigues Da Rocha Costa
{"title":"Clinical value of routine 24-h Holter monitoring in the follow-up of patients with myotonic dystrophy type 1","authors":"Ana Sofia Nogueira Fernandes, Mónica Patrícia Silva Dias, Inês Da Cunha Macedo Conde, Filipe Xavier Silva Vilela, Carla Rafaela Oliveira Ferreira, Jorge Manuel Gomes Sousa Marques, Sérgia Andreia Alves Rodrigues Da Rocha Costa","doi":"10.1016/j.rccl.2025.12.007","DOIUrl":"10.1016/j.rccl.2025.12.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Myotonic dystrophy (DM1) is a hereditary neuromuscular disorder frequently associated with progressive and silent cardiac involvement. Current guidelines recommend regular 24-h Holter monitoring for early detection of arrhythmias and conduction disturbances. We aimed to evaluate the clinical utility of routine Holter monitoring in detecting de novo findings in asymptomatic DM1 patients and its impact on clinical management.</div></div><div><h3>Methods</h3><div>We conducted a retrospective single-centre study including all adult patients with genetically confirmed DM1 who underwent 24-h Holter monitoring between January 2013 and September 2023. Holter findings were compared with standard cardiac screening based on symptoms and ECG. De novo findings were defined as rhythm or conduction disturbances not detected by routine clinical assessment.</div></div><div><h3>Results</h3><div>Forty-six patients were included (52.2% male, mean age 48.0<!--> <!-->±<!--> <!-->10.0 years), with a mean follow-up of 70.5<!--> <!-->±<!--> <!-->35.3 months. All were asymptomatic. Across the cohort, 144 Holter recordings were analysed, with an average of 3.1<!--> <!-->±<!--> <!-->1.7 per patient. Abnormal findings were present in 31 patients (67.4%), mainly atrioventricular conduction disorders (80.6%), including first- and second-degree atrioventricular block, atrial fibrillation/flutter, and non-sustained ventricular tachycardia. Among these, 23 (74.2%) had de novo findings, with therapeutic implications in 5 patients (10.9%).</div></div><div><h3>Conclusions</h3><div>Routine Holter monitoring frequently reveals clinically silent arrhythmias and conduction disturbances in asymptomatic DM1 patients, with a meaningful impact on management in a subset of patients. These findings support its integration into structured follow-up protocols and highlight the need for prospective studies to optimise screening strategies.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 268-274"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-04-13DOI: 10.1016/j.rccl.2026.03.003
Filipa Gerardo, Pedro Custódio, Daniel Faria
{"title":"Artificial intelligence in cardiology education: A performance comparison analysis of large language models","authors":"Filipa Gerardo, Pedro Custódio, Daniel Faria","doi":"10.1016/j.rccl.2026.03.003","DOIUrl":"10.1016/j.rccl.2026.03.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Artificial intelligence (AI) and large language models (LLMs) are being progressively integrated into medical practice. This study aimed to evaluate 7 different LLMs by testing their responses to cardiology-related questions based on European Society of Cardiology (ESC) guidelines.</div></div><div><h3>Methods</h3><div>Cardiology-related questions were formulated using 6 ESC guidelines documents. Multiple-choice questions (MCQs) were created to assess the model's accuracy. The questions were repeated across 3 separate rounds. We also compared general LLM scores with 3 cardiology residents preparing for the ESC European Exam in Core Cardiology.</div></div><div><h3>Results</h3><div>A total of 1096 MCQs were generated. Grok emerged as the top-performing model with a mean accuracy of 85.27%, significantly outperforming Gemini (81.77%; <em>P</em> <!--><<!--> <!-->.001), Le Chat (81.60%; <em>P</em> <!-->=<!--> <!-->.016), Perplexity (82.17%; <em>P</em> <!-->=<!--> <!-->.034), ChatGPT (82.86%; <em>P</em> <!-->=<!--> <!-->.018) and DeepSeek (84.13%; <em>P</em> <!-->=<!--> <!-->.032). All models showed consistent improvement over time, with Grok and Le Chat showing faster performance enhancement (Friedman test, <em>P</em> <!--><<!--> <!-->.001). LLM accuracy was comparable to that of the 3 cardiology residents across all topic groups, with no statistically significant differences (<em>P</em> <!-->=<!--> <!-->.853, <em>P</em> <!-->=<!--> <!-->.691, <em>P</em> <!-->=<!--> <!-->.061).</div></div><div><h3>Conclusions</h3><div>All LLMs exhibit promising accuracy and continuous improvement when answering cardiology-related questions with performances like senior cardiology residents, highlighting their potential for real-world integration in medical practice although. Overall, Grok performed better than the other LLMs. As physicians increasingly incorporate LLMs into clinical decision-making, attention must be paid to the models’ limitations, particularly their lack of self-awareness.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 305-314"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlación genotipo-fenotipo en la miocardiopatía hipertrófica por la variante c.787C>G (p.Gln263Glu) en el gen TPM1","authors":"Silvia Mínguez, Elías Majluf, Jorge Álvarez, Laura Torres-Juan, Damià Heine-Suñer, Tomás Ripoll-Vera","doi":"10.1016/j.rccl.2026.01.002","DOIUrl":"10.1016/j.rccl.2026.01.002","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 320-323"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-02-17DOI: 10.1016/j.rccl.2026.01.001
Marta Catarina Bernardo, Isabel Martins Moreira, Luís Azevedo, José Pedro Guimarães, Sílvia Leão, Renato Margato, Paulo Fontes, Sofia Silva Carvalho, José Ilídio Moreira
{"title":"The prognostic impact of non-progression in cardiac resynchronization therapy","authors":"Marta Catarina Bernardo, Isabel Martins Moreira, Luís Azevedo, José Pedro Guimarães, Sílvia Leão, Renato Margato, Paulo Fontes, Sofia Silva Carvalho, José Ilídio Moreira","doi":"10.1016/j.rccl.2026.01.001","DOIUrl":"10.1016/j.rccl.2026.01.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Among patients who do not demonstrate an echocardiographic response to cardiac resynchronization therapy (CRT), a subgroup with minimal change in remodeling parameters has been identified. Our objective is to evaluate the long-term outcomes of CRT recipients stratified by echocardiographic response.</div></div><div><h3>Methods</h3><div>We conducted a retrospective study of patients with left ventricular ejection fraction (LVEF) ≤<!--> <!-->35% who underwent CRT implantation between 2017 and 2024 and had a follow-up echocardiogram 6–12 months post-procedure. Patients were classified as: progressors (LVEF or left ventricular end-systolic volume [LVESV]<!--> <!--><<!--> <!-->0%), non-progressors (LVEF<!--> <!-->=<!--> <!-->0–10% or LVESV<!--> <!-->=<!--> <!-->0–15%), and responders (LVEF ≥<!--> <!-->10% or LVESV ≥<!--> <!-->15%). The primary endpoint was a composite of all-cause death or heart failure hospitalization.</div></div><div><h3>Results</h3><div>We included 132 patients (68% males, median age 72 years), mean LVEF of 27% (±<!--> <!-->5.0). Overall, 15.2% were progressors, 9.1% non-progressors, and 75.8% responders. Ischemic aetiology was more common in progressors and non-progressors (26% responders, 42% non-progressors, 60% progressors; <em>P</em> <!-->=<!--> <!-->.010). During a mean follow up of 39<!--> <!-->±<!--> <!-->24 months, the primary endpoint occurred in 30.5% of patients, with significantly lower rates in responders (23.2%) compared with non-progressors (58.3%) and progressors (50.0%) (<em>P</em> <!--><<!--> <!-->.005). In multivariate analysis, non-progressors had outcomes comparable to progressors (<em>P</em> <!-->=<!--> <!-->.76) but significantly worse than responders (HR<!--> <!-->=<!--> <!-->4.01).</div></div><div><h3>Conclusions</h3><div>In our population, non-progressors demonstrated similar outcomes to non-responders, underscoring the role of positive remodelling beyond stabilization and highlighting the need to optimize the echocardiographic response to CRT.</div></div>","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 296-304"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
REC: CardioClinicsPub Date : 2026-10-01Epub Date: 2026-06-15DOI: 10.1016/j.rccl.2026.05.003
María Luisa Peña-Peña, Helena Llamas Gómez, Cecilia Prados Murcia
{"title":"Monitorización con Holter de 24 horas en la distrofia miotónica tipo 1: más allá del electrocardiograma de superficie","authors":"María Luisa Peña-Peña, Helena Llamas Gómez, Cecilia Prados Murcia","doi":"10.1016/j.rccl.2026.05.003","DOIUrl":"10.1016/j.rccl.2026.05.003","url":null,"abstract":"","PeriodicalId":36870,"journal":{"name":"REC: CardioClinics","volume":"61 4","pages":"Pages 263-265"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}