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Optical velocity control of microtubules driven by kinesin motors 马达驱动微管的光学速度控制
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6968019
T. Nakahara, H. Shintaku, H. Kotera, R. Yokokawa
{"title":"Optical velocity control of microtubules driven by kinesin motors","authors":"T. Nakahara, H. Shintaku, H. Kotera, R. Yokokawa","doi":"10.1109/NANO.2014.6968019","DOIUrl":"https://doi.org/10.1109/NANO.2014.6968019","url":null,"abstract":"Microtubule gliding on a kinesin-coated surface may be applied as a nanoactuator to manipulate nanoscale materials in a microfluidic environment. However, controlling the velocity and direction of microtubule gliding has been a major challenge for bioengineering. To develop a novel method of molecular manipulation, we propose a technique to control the velocity of gliding microtubules by light irradiance, which mediates the temperature of the assay. To measure the temperature, we integrated a gold-resistive temperature detector with the substrate. After temperature calibration, we measured the relationship between temperature and light irradiance. The results showed that the temperature increased approximately by 10°C by adjusting irradiance from zero to 13.5 W/cm2. In the gold area, the velocity of microtubules increased 1.8-fold at an irradiance of 13.5 W/cm2.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122616481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a microfluidic perfusion system for patch clamp recording 膜片钳记录微流控灌注系统的研制
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6968092
Runhuai Yang, K. Lai, N. Xi, Jie Yang
{"title":"Development of a microfluidic perfusion system for patch clamp recording","authors":"Runhuai Yang, K. Lai, N. Xi, Jie Yang","doi":"10.1109/NANO.2014.6968092","DOIUrl":"https://doi.org/10.1109/NANO.2014.6968092","url":null,"abstract":"In this paper, the design of a microfluidic perfusion system for patch clamp recording is reported. The microfluidic perfusion system mainly consists of a polydimethylsiloxane (PDMS) chamber and a micro drug delivery pipette. The performance of the perfusion system was verified by conducting patch clamp recording of neuroblastoma cells. This system provides a method to precisely perform drug delivery without any disturbance of the seal condition.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122059383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double grating antireflection nanostructure based on nano-cone 基于纳米锥的双光栅增透纳米结构
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6968084
Xiaoting Zhi, Chuanhong Liu, Fengyun Zhao, Yucui Wu, M. Zhang, Zhaoyu Zhang
{"title":"Double grating antireflection nanostructure based on nano-cone","authors":"Xiaoting Zhi, Chuanhong Liu, Fengyun Zhao, Yucui Wu, M. Zhang, Zhaoyu Zhang","doi":"10.1109/NANO.2014.6968084","DOIUrl":"https://doi.org/10.1109/NANO.2014.6968084","url":null,"abstract":"A type of half-embedded cone grating nanostructure is proposed for antireflection (AR). It can achieve reflectance of down to 0.5% under normal incidence and 6% under incidence angle as large as 40 degrees in the 300-1100 nm wavelength range. Besides, it can maintain good performance in a large dimension range with a fixed period or vertex angle. Furthermore, the refractive index of the grating can be varied in a large range while keeping the high antireflective ability, namely that the material of the grating can be freely chosen without the limitation of single material. More importantly, it can tolerates the interlayer between the double cone grating much with just a slightly fluctuation of the reflectance less than 0.03%. These properties reduce both the design difficulty and the fabrication difficulty, making it a potential solution for use in various applications such as renewable energy and optical-electro devices.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"2 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122163122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engineering large gelatin nanospheres coated with quantum dots for targeted delivery of human osteosarcoma with enhanced cellular internalization 工程大明胶纳米球包被量子点靶向递送人骨肉瘤与增强细胞内化
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6967978
W. H. Tse, Laszlo Gyenis, D. Litchfield, Jin Zhang
{"title":"Engineering large gelatin nanospheres coated with quantum dots for targeted delivery of human osteosarcoma with enhanced cellular internalization","authors":"W. H. Tse, Laszlo Gyenis, D. Litchfield, Jin Zhang","doi":"10.1109/NANO.2014.6967978","DOIUrl":"https://doi.org/10.1109/NANO.2014.6967978","url":null,"abstract":"Due to the special structures of cell membrane, good internalization is one of major concerns on using large nanospheres as carriers for labeling and treatment of cancer. We herein report fluorescent gelatin nanosphers (GNs) coated with CdSe/ZnS quantum dots (QDs) to form a viable vehicle for theranostic applications. Anti-human immunoglobulin G Fab formation, anti-IgG Fab, is bioconjugated on to the hybrid fluorescent GNs for targeted delivery (QDs-GNs-anti-IgG Fab). Human osteosarcoma cell line is used in studying the interaction between hybrid fluorescent GNs with and without anti-IgG Fab. The average particle size of the fluorescent GNs bioconjugated with antibodies is estimated at 480±50 nm. The emission (λem) of the fluorescent GNs is around 652 nm. The quantitative analysis on the surface modification and bioconjugation of GNs has been discussed in this paper. The three-dimensional z-stacking fluorescent images reveal that the hybrid GNs with anti-IgG Fab has ~1.5 times increase in internalization with human osteosarcoma cells than GNs without the antibody fragment. The improved cellular interaction of the QDs-GN-anti IgG Fab is attributed to the bioconjugation of antibodies which can provide specificity for targeted drug delivery. Relative cell viability (%) is larger than 80% for each type of functionalized GNs up to 40 μg/mL. We expect that the functionalized gelatin sphere can offer an effective theranostic tool for targeted drug delivery and direct imaging confirmation simultaneously.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131341251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Nanoscale engineering optical nonlinearities and nanolasers 纳米工程光学非线性与纳米激光器
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6968158
Y. Fainman, F. Vallini, M. Puckett, J. Smalley, Q. Gu, O. Bondarenko, J. Shane, A. Simic, B. Slutsky, A. Mizrahi, M. Khajavikhan, J. Lee
{"title":"Nanoscale engineering optical nonlinearities and nanolasers","authors":"Y. Fainman, F. Vallini, M. Puckett, J. Smalley, Q. Gu, O. Bondarenko, J. Shane, A. Simic, B. Slutsky, A. Mizrahi, M. Khajavikhan, J. Lee","doi":"10.1109/NANO.2014.6968158","DOIUrl":"https://doi.org/10.1109/NANO.2014.6968158","url":null,"abstract":"Dense photonic integration requires miniaturization of materials, devices and subsystems, including passive components (e.g., engineered composite metamaterials, filters, etc.) and active components (e.g., lasers, modulators, detectors). This paper discusses passive and active devices that recently have been demonstrated in our laboratory and design, fabrication and testing of nanolasers constructed using metal-dielectric-semiconductor resonators confined in all three dimensions and operating at room temperature.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125526020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of CNT based Nano bio-sensor for virus detection 基于碳纳米管的纳米生物传感器的病毒检测分析
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6968064
Aditya Poonia, Abhimanyu Dabas, G. Chaudhary, Lavanya Aggarwal, Anuj Kumar, H. Kumar, K. Singh
{"title":"Analysis of CNT based Nano bio-sensor for virus detection","authors":"Aditya Poonia, Abhimanyu Dabas, G. Chaudhary, Lavanya Aggarwal, Anuj Kumar, H. Kumar, K. Singh","doi":"10.1109/NANO.2014.6968064","DOIUrl":"https://doi.org/10.1109/NANO.2014.6968064","url":null,"abstract":"In the present study, a Nano mechanical resonator is designed and used for the process of virus detection. The biosensor is designed using the single-walled carbon nano-tube (SWCNT). The investigations are done on the vibrations of the cantilevered sensor, when the virus is present at the tip. The cantilevered SWCNT will be able to identify the biomolecule that may be present at the tip of the resonator. The calculations for determining the natural frequency are done using the finite difference method. A comparison of the results has been done with the exact solution. It is found that the designed sensor is able to provide measureable frequency shifts even when a light virus approaches the cantilever. The sensitivity of the entire system is found to be able to detect the virus in the zeptogram scale. It is discovered that the natural frequency as calculated by the finite difference method match the frequency as calculated by the exact solution.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131829644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Synthesis of silicon nanowires by metal-catalyst-free process 无金属催化剂法合成硅纳米线
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6968013
T. Ishiyama, Satoru Morishima, Y. Ishii, M. Fukuda
{"title":"Synthesis of silicon nanowires by metal-catalyst-free process","authors":"T. Ishiyama, Satoru Morishima, Y. Ishii, M. Fukuda","doi":"10.1109/NANO.2014.6968013","DOIUrl":"https://doi.org/10.1109/NANO.2014.6968013","url":null,"abstract":"The synthesis of single-crystal silicon (Si) nanowires by a metal-catalyst-free vapor-liquid-solid (VLS) process was studied. Silicon nanowires have been successfully synthesized by simple thermal treatment without any metal catalyst. For cases without metal catalysts, Si nanowires are grown by VLS processes assisted by sulfur. It is thought that single-crystal Si nanowires are grown by a VLS process in which the silicon sulfides produced by a reaction between Si and sulfur act as both molten eutectic alloy droplets and the source gases for nanowire growth. Si nanowires were synthesized by the sulfur-assisted thermal chemical vapor transport process without the using of any metal catalyst.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132250098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flexible temperature sensor with laser scribed graphene oxide 柔性温度传感器与激光刻写氧化石墨烯
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6967998
R. Kazemzadeh, W. Kim
{"title":"Flexible temperature sensor with laser scribed graphene oxide","authors":"R. Kazemzadeh, W. Kim","doi":"10.1109/NANO.2014.6967998","DOIUrl":"https://doi.org/10.1109/NANO.2014.6967998","url":null,"abstract":"Fabrication of flexible temperature sensor array using reduced graphene oxide (rGO) by laser scribing is presented. This unique type of sensor employs graphene as sensing material in order to generate temperature distribution map of human skin, which is important for distinguishing some physiological changes. This device is flexible and can be attached easily on wrist or other body parts. CO2 laser is used to reduce the graphene oxide into highly conductive rGO with less than 3×10-3 S/m in resistivity. Laser-induced reduction is a very fast, facile, chemical-free, room temperature process that uses the photo-thermal reactivity of GO.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132590921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Anomaly in current distribution of multiwall carbon nanotube bundles at high frequencies 高频多壁碳纳米管束电流分布的异常
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6967950
Esmat Kishani Farahani, R. Sarvari
{"title":"Anomaly in current distribution of multiwall carbon nanotube bundles at high frequencies","authors":"Esmat Kishani Farahani, R. Sarvari","doi":"10.1109/NANO.2014.6967950","DOIUrl":"https://doi.org/10.1109/NANO.2014.6967950","url":null,"abstract":"In this paper, for the first time, current distribution inside multiwall carbon nanotube (MWCNT) bundles is studied in the high frequency range in which resistance becomes saturated. It is shown that current distribution of MWCNT bundles in this range is not strictly decreasing vs. distance from surface as in Cu wires.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133109960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An improved technology without mercury for cellular piercing 一种改进的无汞细胞穿刺技术
14th IEEE International Conference on Nanotechnology Pub Date : 2014-12-01 DOI: 10.1109/NANO.2014.6967954
Peng Pan, Ruihua Chen, Tao Chen, Changhai Ru
{"title":"An improved technology without mercury for cellular piercing","authors":"Peng Pan, Ruihua Chen, Tao Chen, Changhai Ru","doi":"10.1109/NANO.2014.6967954","DOIUrl":"https://doi.org/10.1109/NANO.2014.6967954","url":null,"abstract":"Fertilization performed by intracytoplasmic sperm injection(ICSI) using a piezo unit is recognized as the most practical technique not only for endangered species but also for humans. However what depresses us is the toxicity of mercury which may pose a bad influence on the health of humans and the competence of mouse oocytes. This limitation confines the use of this technique in hospitals and laboratories. What`s more, outcomes gained by the substitutes for mercury reducing the lateral oscillation is no match for mercury. Under this circumstance, a modified piezo-driven ICSI methodology, eliminating the application of mercury, is proposed in this paper used for the cleavage of mouse oocytes. By means of this modified methodology, a desirable result of cleavage for the cellular piercing was gained, a subtle lateral vibration of injection pipette smaller than its outer diameter obtained with the appropriate frequency and voltage. In view of the accomplishments we have acquired and the enhancements of manufacture for pipettes, this method will have a tremendous potential in hospitals and laboratories.","PeriodicalId":367660,"journal":{"name":"14th IEEE International Conference on Nanotechnology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116743320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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