Journal of Psoriasis and Psoriatic Arthritis最新文献_第9页

Correlation Between Insulin Resistance and Psoriatic Arthritis Disease Activity: A Cross-Sectional Study. 胰岛素抵抗与银屑病关节炎活动性的相关性研究

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-10-01 Epub Date: 2023-05-31 DOI: 10.1177/24755303231180508

Yuliasih Yuliasih, Martino Handoyo, Lita Diah Rahmawati, Sony Wibisono, Nabilatun Nisa

{"title":"Correlation Between Insulin Resistance and Psoriatic Arthritis Disease Activity: A Cross-Sectional Study.","authors":"Yuliasih Yuliasih, Martino Handoyo, Lita Diah Rahmawati, Sony Wibisono, Nabilatun Nisa","doi":"10.1177/24755303231180508","DOIUrl":"10.1177/24755303231180508","url":null,"abstract":"Objectives: Most psoriatic arthritis (PsA) research and studies focus solely on the skin and joint manifestations, but there is also an increased risk of metabolic disorders, including insulin resistance (IR). This study aims to discover the relationship between IR and disease activity (DA) in PsA and its phenotype.Materials and methods: Patients with PsA classified using the CASPAR criteria with the disease activity was measured using the DAPSA score, and IR was identified as an elevated HOMA-IR of >2.5. The disease phenotype was determined with Moll and Wright's classification of the PsA subtype. The Pearson correlation test examined the relationship between DA and IR. The descriptive analysis was conducted to determine the relationship between the DAPSA score and HOMA-IR value in each PsA phenotype. All tests were two-tailed, analysed with GraphPad Prism 9, and a P-value of less than .05 was considered statistically significant.Results: From thirty-one patients, there was a strong and positive relationship between DA and IR (r = .768, P = .000). We also observed variations in DAPSA score and HOMA-IR value across different phenotypes, with symmetrical polyarthritis exhibiting the highest DAPSA score (21.55 ± 3.50) and HOMA-IR value (2.913 ± .5392) despite asymmetrical oligoarthritis that being the most frequent phenotype.Conclusion: Our study revealed a significant association between disease activity and insulin resistance in PsA patients, with the symmetrical polyarthritis phenotype demonstrating the highest levels of DAPSA score and IR value. This finding allowed rheumatologists to behold this manifestation and could improve PsA patients' long-term outlook.","PeriodicalId":36656,"journal":{"name":"Journal of Psoriasis and Psoriatic Arthritis","volume":" ","pages":"129-133"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47232369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to Likelihood of COVID-19 Vaccination Among Individuals Living With Psoriatic Disease: Results From a Large Real-World Survey. 银屑病患者接种COVID-19疫苗的可能性的勘误表:来自大型现实世界调查的结果

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-10-01 Epub Date: 2023-08-23 DOI: 10.1177/24755303231195873

引用次数: 0

Corrigendum to Successful Treatment of Guttate Psoriasis With Ixekizumab: A Case Series. Ixekizumab成功治疗口腔银屑病的更正：一系列病例

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-10-01 Epub Date: 2023-08-31 DOI: 10.1177/24755303231195862

引用次数: 0

Corrigendum to Practice Patterns of Palmoplantar Pustulosis: Patient Demographics and Treatment Options. 掌跖脓疱病的实践模式的勘误表:患者人口统计和治疗方案

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-10-01 Epub Date: 2023-08-23 DOI: 10.1177/24755303231195875

引用次数: 0

Paradoxical Effects of Depression on Psoriatic Arthritis Outcomes in a Combined Psoriasis-Psoriatic Arthritis Center 抑郁对银屑病-银屑病关节炎联合中心银屑病关节炎结局的矛盾影响

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-06-26 DOI: 10.1177/24755303231186405

Rebecca H. Haberman, Seungha Um, Sydney Catron, Alan Chen, Eileen Lydon, Malavikalakshmi Attur, Andrea L. Neimann, Soumya Reddy, Andrea Troxel, Samrachana Adhikari, Jose U. Scher

{"title":"Paradoxical Effects of Depression on Psoriatic Arthritis Outcomes in a Combined Psoriasis-Psoriatic Arthritis Center","authors":"Rebecca H. Haberman, Seungha Um, Sydney Catron, Alan Chen, Eileen Lydon, Malavikalakshmi Attur, Andrea L. Neimann, Soumya Reddy, Andrea Troxel, Samrachana Adhikari, Jose U. Scher","doi":"10.1177/24755303231186405","DOIUrl":"https://doi.org/10.1177/24755303231186405","url":null,"abstract":"Backgroud Psoriatic arthritis (PsA) is a chronic, inflammatory arthritis that, when left untreated, can lead to erosions, deformities and decrease in quality of life. PsA is known to be associated with multiple comorbidities, including cardiovascular, metabolic and mental health syndromes, all of which can increase its overall morbidity and mortality. Objective To characterize a cohort of patients with PsA and understand the impact of depression on PsA outcome measures. Methods 527 consecutive patients with PsA were enrolled in an observational, longitudinal registry that followed them prospectively at standard of care visits. Demographics, medical history, medication use, and clinical exam were all recorded. Results Depression was reported in 22.8% of the population, anxiety in 18%, and attention deficit hyperactivity disorder in 4%. Depression was more common in female participants (P < .001). At baseline, individuals with PsA and concomitant depression had similar tender and swollen joint counts and RAPID3 compared to those without depression, and had lower body surface area affected by psoriasis (P = .04). At year one, all patients had improvement in clinical outcomes. However, patients with depression had a significantly higher tender joint count compared to those without depression (P = .001), despite similar swollen joint count and body surface area. Conclusion In patients with depression, there is a discrepancy between improvement in physician assessed measures and patient reported outcomes. These observations underscore the importance of addressing depression and psychological distress as part of PsA treatment outcomes and points towards the need to address residual pain through co-adjuvant approaches.","PeriodicalId":36656,"journal":{"name":"Journal of Psoriasis and Psoriatic Arthritis","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135608493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to improve people-centred healthcare in dermatology? 如何改善皮肤科以人为本的医疗保健?

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-06-20 DOI: 10.55788/27076e04

R. Sommer, M. Augustin

{"title":"How to improve people-centred healthcare in dermatology?","authors":"R. Sommer, M. Augustin","doi":"10.55788/27076e04","DOIUrl":"https://doi.org/10.55788/27076e04","url":null,"abstract":"People with chronic skin diseases, such as psoriasis, experience multifaceted impairments that include physical symptoms, such as pain, psychological symptoms, such as anxiety, and social impairments, such as stigmatisation. To address this broad spectrum of impairments, a holistic healthcare approach is needed. The World Health Organization has established the people-centred model of care, in which health services adopt the perspective of people affected and their environment. The needs of patients are respected, and patients are put at the centre of care. This model was also adopted by the global report on psoriasis, which aims to improve the wellbeing of the affected people. This paper gives a brief overview of the status quo and an outline of how to improve people-centred care and patient orientation in dermatology, specifically for people with psoriasis. This includes the application of shared decision-making. Although only a few patient decision aids for psoriasis have been published, promising results regarding the reimbursement of shared decision-making applications in the hospital setting by health insurances are available, which also refer to dermatology departments. In addition, the use of patient-reported outcomes is of great importance to give patients a voice in their own healthcare. In accordance with the people-centred model, it is recommended to not only assess patients' perspectives, such as their needs, goals, and treatment benefits, but also the needs and treatment benefits of the patients' environment, such as their partner and treating healthcare professionals. One recent example of such a people-centred approach is the POSITIVE-study, which is the first study assessing the treatment effect on the wellbeing of patients with psoriasis. Moreover, the treatment benefit on physicians' satisfaction and patients' partners' lives is being evaluated. Therefore, it could act as a best practice example of how to integrate a people-centred approach in research.","PeriodicalId":36656,"journal":{"name":"Journal of Psoriasis and Psoriatic Arthritis","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75103410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psoriasis and COVID-19: findings from PsoProtectMe. 牛皮癣和COVID-19:来自PsoProtectMe的研究结果。

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-06-19 DOI: 10.55788/819f9152

Conn McGrath, M. Yates, Zenas Z. N. Yiu, S. Langan, T. Tsakok, N. Dand, Kayleigh Mason, Helen McActeer, F. Meynell, B. Coker, A. Vincent, D. Urmston, A. Vesty, Georgia Sewell, J. Kelly, Camille Lancelot, L. Moorhead, H. Bachelez, Katie Bechem, F. Capon, C. Contreras, C. de la Cruz, P. Di Meglio, P. Gisondi, D. Jullien, J. Lambert, L. Naldi, S. Norton, L. Puig, P. Spuls, T. Torres, R. Warren, Hoseah Waweru, J. Weinman, J. Galloway, C. Griffiths, J. Barker, Catherine H. Smith, S. Mahil

引用次数: 0

Pathogenesis of Psoriatic Arthritis 银屑病关节炎的发病机制

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-06-19 DOI: 10.55788/c9ea6682

V. Chandran

引用次数: 0

Inflammatory diseases – a new way of thinking 炎性疾病——一种新的思维方式

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-06-19 DOI: 10.55788/a93901e6

J. Prinz

引用次数: 0

Can Serum Fetuin-A be Used as a Marker for Cardiovascular Involvement in Psoriatic Patients? 血清胎蛋白-A可以作为银屑病患者心血管病变的标志物吗？

Journal of Psoriasis and Psoriatic Arthritis Pub Date : 2023-04-01 Epub Date: 2023-02-15 DOI: 10.1177/24755303221135570

Hanan M Saleh, Aliaa S Sheha, Nardeen N Eskander, Ahmed F Elhawatky, Samah I Hassen

{"title":"Can Serum Fetuin-A be Used as a Marker for Cardiovascular Involvement in Psoriatic Patients?","authors":"Hanan M Saleh, Aliaa S Sheha, Nardeen N Eskander, Ahmed F Elhawatky, Samah I Hassen","doi":"10.1177/24755303221135570","DOIUrl":"10.1177/24755303221135570","url":null,"abstract":"Background: Psoriasis is a systemic inflammatory disorder. It is associated with increased risk of developing other chronic health diseases such cardiovascular disorders. Fetuin A is a glycoprotein that is present in blood serum. It may prevent vascular calcification by forming calciprotien particles; which are formed from their attachment with phosphate and calcium complexes.Aim: The aim of this study was to measure serum Fetuin A in Psoriatic patients and correlate its level with cardiac events and risks in these patients using CT calcium (Ca) scoring.Patients and methods: 24 psoriatic patients (healthy without apparent cardiac risks to detect subclinical events if present) and 24 age and sex matched controls were tested for serum Fetuin A and underwent coronary calcium scoring by multidetector computed tomography (CT) scan. Psoriasis area and severity index (PASI) score for each patient was measured and was correlated with serum Fetuin A and CT calcium (Ca) scoring. Serum Fetuin A was compared between cases and controls and was correlated with coronary calcium score.Results: There was highly statistically significant decrease in serum Fetuin A level in psoriatic group compared to control group (P-value < .001). There was highly statistically significant negative correlation between calcium score and the level of serum Fetuin A (P-value < .001). No statistically significant correlation was found between the serum level of Fetuin A and the psoriasis severity.Conclusion: Serum Fetuin A is a simple, easy diagnostic tool to evaluate subclinical atherosclerosis in psoriatic patients.","PeriodicalId":36656,"journal":{"name":"Journal of Psoriasis and Psoriatic Arthritis","volume":"8 1","pages":"66-73"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45463654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0