Epilepsy and Behavior Reports最新文献_第10页

Transorbital intraoperative electrocorticography-guided surgical resection for medically refractory developmental epileptic encephalopathy with spike-wave activation in sleep 经眶内皮层电图引导的手术切除治疗伴有睡眠中尖峰波激活的药物难治性发育性癫痫脑病

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100712

Michael E. Baumgartner , Sudha Kessler , Alier J. Franco , Samuel B. Tomlinson , Benjamin C. Kennedy

{"title":"Transorbital intraoperative electrocorticography-guided surgical resection for medically refractory developmental epileptic encephalopathy with spike-wave activation in sleep","authors":"Michael E. Baumgartner , Sudha Kessler , Alier J. Franco , Samuel B. Tomlinson , Benjamin C. Kennedy","doi":"10.1016/j.ebr.2024.100712","DOIUrl":"10.1016/j.ebr.2024.100712","url":null,"abstract":"<div><div>Developmental epileptic encephalopathy with spike-wave activation in sleep (DEE-SWAS) is an epilepsy syndrome of childhood characterized by developmental delay or regression with significant abnormal epileptiform activity during sleep. In some cases, DEE-SWAS with an identified focal lesion is treated with surgical resection. The authors report an unusual case of focal DEE-SWAS that was successfully treated via transorbital resection with intraoperative electrocorticography (iECoG). The patient is an 11-year-old boy with a history of medication-responsive seizures who presented with cognitive and language decline. Electroencephalography demonstrated abnormal electrographic activity during sleep consistent with DEE-SWAS. Imaging and electrographic studies identified a probable epileptogenic zone anterior and adjacent to Broca’s area. He underwent stereoelectroencephalography followed by focal resection with iECoG, which resulted in resolution of EEG abnormalities, improved word finding, and no further cognitive decline. While DEE-SWAS is not typically managed with surgical intervention, focal resection in carefully selected patients can achieve favorable outcomes.</div></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"28 ","pages":"Article 100712"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuromorphometric associations with mood, cognition, and self-reported exercise levels in epilepsy and healthy individuals 对健康人和癫痫患者的神经形态测量、情绪、认知和自我报告的运动水平之间关系的试点调查

IF 1.5

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2023.100643

Ayushe A. Sharma , D. Mackensie Terry , Johanna L. Popp , Jerzy P. Szaflarski , Roy C. Martin , Rodolphe Nenert , Manmeet Kaur , Gabrielle A. Brokamp , Mark Bolding , Jane B. Allendorfer

{"title":"Neuromorphometric associations with mood, cognition, and self-reported exercise levels in epilepsy and healthy individuals","authors":"Ayushe A. Sharma , D. Mackensie Terry , Johanna L. Popp , Jerzy P. Szaflarski , Roy C. Martin , Rodolphe Nenert , Manmeet Kaur , Gabrielle A. Brokamp , Mark Bolding , Jane B. Allendorfer","doi":"10.1016/j.ebr.2023.100643","DOIUrl":"10.1016/j.ebr.2023.100643","url":null,"abstract":"<div><p>Regular physical activity may promote beneficial neuroplasticity, e.g., increased hippocampus volume. However, it is unclear whether self-reported physical exercise in leisure (PEL) levels are associated with the brain structure features demonstrated by exercise interventions. This pilot study investigated the relationship between PEL, mood, cognition, and neuromorphometry in patients with idiopathic generalized epilepsy (IGEs) compared to healthy controls (HCs). Seventeen IGEs and 19 age- and sex-matched HCs underwent magnetic resonance imaging (MRI) at 3T. The Baecke Questionnaire of Habitual Physical Activity, Profile of Mood States, and Montreal Cognitive Assessment (MoCA) assessed PEL, mood, and cognition, respectively. Structural MRI data were analyzed by voxel- and surface-based morphometry. IGEs had significantly lower PEL (<em>p</em> < 0.001), poorer mood (<em>p</em> = 0.029), and lower MoCA scores (<em>p</em> = 0.027) than HCs. These group differences were associated with reduced volume, decreased gyrification, and altered surface topology (IGEs < HCs) in frontal, temporal and cerebellar regions involved in executive function, memory retrieval, and emotional regulation, respectively.</p><p>These preliminary results support the notion that increased PEL may promote neuroplasticity in IGEs, thus emphasizing the role of physical activity in promoting brain health in people with epilepsy.</p></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"25 ","pages":"Article 100643"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589986423000618/pdfft?md5=a2c6dbb7a49744091161db45f385fe96&pid=1-s2.0-S2589986423000618-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139189688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MRI detection of mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) on T1WI-CHESS 磁共振成像在 T1WI-CHESS 上检测到伴有少突胶质增生的轻度皮质发育畸形 (MOGHE)

IF 1.5

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100674

Elly Arizono , Zen-ichi Tanei , Keiya Iijima , Yukio Kimura , Yoko Shigemoto , Hiroyuki Maki , Midori Kusama , Kumiko Murayama , Masaki Iwasaki , Takashi Saito , Yuko Saito , Kazuhiro Saito , Noriko Sato

{"title":"MRI detection of mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) on T1WI-CHESS","authors":"Elly Arizono , Zen-ichi Tanei , Keiya Iijima , Yukio Kimura , Yoko Shigemoto , Hiroyuki Maki , Midori Kusama , Kumiko Murayama , Masaki Iwasaki , Takashi Saito , Yuko Saito , Kazuhiro Saito , Noriko Sato","doi":"10.1016/j.ebr.2024.100674","DOIUrl":"https://doi.org/10.1016/j.ebr.2024.100674","url":null,"abstract":"<div><p>Mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) is a recently proposed epileptogenic entity that is difficult to detect on MRI. We present a case of MOGHE that was successfully detected on T1WI-chemical shift-selective saturation (CHESS) MRI. The clinical presentation, MRI including T1WI-CHESS, functional images, and pathology findings of a 14-year-old Japanese girl diagnosed with MOGHE are described. T1WI-CHESS revealed an abnormal high signal along the affected lesion, whereas the findings shown by the other MR sequences were less obvious; interictal fluorodeoxyglucose-positron emission tomography indicated slightly decreased accumulation in the lesion, and subtraction ictal single photon emission computed tomography co-registered to MRI showed an increased blood flow. Together these observations suggest that T1WI-CHESS may be a useful MR sequence for detecting the lesions in patients with MOGHE.</p></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"26 ","pages":"Article 100674"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589986424000315/pdfft?md5=674c5010e112cd7a73fa5f46629d71a6&pid=1-s2.0-S2589986424000315-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140905652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opercular myoclonic-anarthric status (OMASE) secondary to anti-Hu paraneoplastic neurological syndrome 继发于抗胡副肿瘤性神经综合征的厣肌强直-无张力状态（OMASE）

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100703

César Romero, Alonso Quijada, Gabriel Abudinén, Catherine Céspedes, Ledda Aguilera

引用次数: 0

Exploring patients’ views on telephone consultations in the seizure clinic: A qualitative interview study 探索患者对癫痫发作门诊电话咨询的看法：定性访谈研究

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100705

Joseph Ford, Markus Reuber

{"title":"Exploring patients’ views on telephone consultations in the seizure clinic: A qualitative interview study","authors":"Joseph Ford, Markus Reuber","doi":"10.1016/j.ebr.2024.100705","DOIUrl":"10.1016/j.ebr.2024.100705","url":null,"abstract":"<div><p>The COVID-19 pandemic brought telemedicine into mainstream medical practice. Although it is widely agreed that telemedicine could be beneficial for patients with seizures, there has been little prior research investigating patients’ views on this subject. In this qualitative study, we conducted semi-structured interviews with 10 patients and one companion about their experiences of telemedicine. We also received written thoughts from one additional patient. Participants’ views fell under three broad themes. The first, “Convenience and practicality”, saw participants praising the flexibility of telephone consultations while noting that such consultations could introduce new practical problems. The second, “(Lack of) shared presence”, covered participants’ generally negative feelings about not being in the same room as their neurologists. The third, “Situation dependency”, saw participants drawing fine distinctions about the circumstances in which face-to-face and telephone consultations were suitable. Overall, although patients with seizures are generally positive about the convenience of telephone consultations, they have concerns about how they may lead to misunderstandings or affect the doctor-patient relationship. These concerns could be assuaged to some extent by offering video consultations or scheduling alternating telephone and face-to-face consultations<em>.</em></p></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"28 ","pages":"Article 100705"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589986424000625/pdfft?md5=78a3dbdb16ec4fe913492f2ce585c816&pid=1-s2.0-S2589986424000625-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142041252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of steroids on super-refractory status epilepticus in tick-borne meningoencephalitis 类固醇对蜱传脑膜脑炎超级难治性癫痫状态的影响

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100710

Christine Heuer , Claudio Togni , Marian Galovic , Anna Czernuszenko , Giovanna Brandi , Ignazio de Trizio

{"title":"Effects of steroids on super-refractory status epilepticus in tick-borne meningoencephalitis","authors":"Christine Heuer , Claudio Togni , Marian Galovic , Anna Czernuszenko , Giovanna Brandi , Ignazio de Trizio","doi":"10.1016/j.ebr.2024.100710","DOIUrl":"10.1016/j.ebr.2024.100710","url":null,"abstract":"<div><p>We report a unique case of super-refractory status epilepticus (SRSE) secondary to tick-borne encephalitis (TBE) to evaluate the therapeutic challenges and potential benefits of steroid treatment in this context. A previously healthy 31-year-old woman was admitted to the hospital with fever, headache, vertigo, and meningismus, ultimately diagnosed with TBE. Despite empirical antimicrobial treatment, the patient’s condition deteriorated, leading to coma and SRSE. Various antiseizure medications and sedatives were administered without sustained success. Steroid treatment was initiated due to elevated intracranial pressure and persistent seizure activity. Following the administration of dexamethasone, electrographic status epilepticus resolved, though the patient developed clinical signs of increased intracranial pressure necessitating decompressive craniectomy. The patient’s condition stabilized with a combination of antiseizure medicazions. Despite cessation of SRSE, the patient remained in a minimally conscious state at discharge, showing only gradual improvement over time. The use of steroids in TBE is controversial, with limited reports of potential benefits. In this case, steroid administration coincided with the cessation of SRSE, and authors explore its potential benefit considering its immunomodulatory effects.</p></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"28 ","pages":"Article 100710"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589986424000674/pdfft?md5=c59a8d84cb0982384a32a5543b0f66f6&pid=1-s2.0-S2589986424000674-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142239856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delineating abnormal individual structural covariance brain network organization in pediatric epilepsy with unilateral resection of visual cortex 单侧切除视觉皮层的小儿癫痫患者异常个体结构协方差脑网络组织的划分

IF 1.5

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100676

Liang Zhang , Bei Zhuang , Mengyuan Wang , Jie Zhu , Tao Chen , Yang Yang , Haoting Shi , Xiaoming Zhu , Li Ma

{"title":"Delineating abnormal individual structural covariance brain network organization in pediatric epilepsy with unilateral resection of visual cortex","authors":"Liang Zhang , Bei Zhuang , Mengyuan Wang , Jie Zhu , Tao Chen , Yang Yang , Haoting Shi , Xiaoming Zhu , Li Ma","doi":"10.1016/j.ebr.2024.100676","DOIUrl":"10.1016/j.ebr.2024.100676","url":null,"abstract":"<div><p>Although several previous studies have used resting-state functional magnetic resonance imaging and diffusion tensor imaging to report topological changes in the brain in epilepsy, it remains unclear whether the individual structural covariance network (SCN) changes in epilepsy, especially in pediatric epilepsy with visual cortex resection but with normal functions. Herein, individual SCNs were mapped and analyzed for seven pediatric patients with epilepsy after surgery and 15 age-matched healthy controls. A whole-brain individual SCN was constructed based on an automated anatomical labeling template, and global and nodal network metrics were calculated for statistical analyses. Small-world properties were exhibited by pediatric patients after brain surgery and by healthy controls. After brain surgery, pediatric patients with epilepsy exhibited a higher shortest path length, lower global efficiency, and higher nodal efficiency in the cuneus than those in healthy controls. These results revealed that pediatric epilepsy after brain surgery, even with normal functions, showed altered topological organization of the individual SCNs, which revealed residual network topological abnormalities and may provide initial evidence for the underlying functional impairments in the brain of pediatric patients with epilepsy after surgery that can occur in the future.</p></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"27 ","pages":"Article 100676"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589986424000339/pdfft?md5=69d7b32d4b24b2e7ba184cb1e43e2271&pid=1-s2.0-S2589986424000339-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141049364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive outcomes after magnetic resonance-guided laser interstitial thermal therapy for mesial temporal lobe epilepsy in adolescent patients 磁共振引导下的激光间质热疗治疗青少年颞叶中叶癫痫后的认知效果

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100723

Jonathon M. Cavaleri , Jenna A. Chiang , Danielle M. Wishart , Keiko M. Kang , Patrick R. Ng , Leanne Mendoza , Kenneth Hartline , Michele Van Hirtum-Das , Latanya D. Agurs , Madeline Kahan , Brittany Jordan , Charles Y. Liu , Brian Lee , Peter A. Chiarelli , Jason K. Chu

{"title":"Cognitive outcomes after magnetic resonance-guided laser interstitial thermal therapy for mesial temporal lobe epilepsy in adolescent patients","authors":"Jonathon M. Cavaleri , Jenna A. Chiang , Danielle M. Wishart , Keiko M. Kang , Patrick R. Ng , Leanne Mendoza , Kenneth Hartline , Michele Van Hirtum-Das , Latanya D. Agurs , Madeline Kahan , Brittany Jordan , Charles Y. Liu , Brian Lee , Peter A. Chiarelli , Jason K. Chu","doi":"10.1016/j.ebr.2024.100723","DOIUrl":"10.1016/j.ebr.2024.100723","url":null,"abstract":"<div><div>Surgical treatment of medication-resistant mesial temporal lobe epilepsy (MTLE) is associated with cognitive deficits. Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) for MTLE has been shown to result in superior cognitive outcomes in adults when compared to open surgical resection. However, data regarding postoperative cognitive outcomes in adolescent and pediatric patients is limited. We retrospectively reviewed sequential cases of pediatric patients who underwent MRgLITT for MTLE between 2017 and 2023. Patients who had complete preoperative and 12 month postoperative neuropsychological evaluation were analyzed for changes in the neuropsychological domains of cognition, memory, executive functioning, visual scanning, graphomotor speed, and fine motor speed/dexterity. Six adolescent patients who underwent MRgLITT for MTLE (x̄ age = 19.0 years, <em>SD</em> = 1.2) and had complete preoperative and postoperative neuropsychological evaluations were included in the analysis. There were no statistically significant changes across neuropsychological domains when comparing pre- and postoperative cognitive evaluations, including verbal memory scores. Clinically significant changes in phonemic fluency were observed when examining side-specific effects and improved for patients who received right-sided MRgLITT but declined for patients who received left-sided MRgLITT. 50 % of patients achieved Engel I outcome at last follow-up. Our preliminary results suggest minimal adverse neuropsychologic effects following MRgLITT for adolescent MTLE, including preservation of verbal memory. Clinical outcomes were similar with those reported in the literature.</div></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"28 ","pages":"Article 100723"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142573485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-reported exercise engagement and seizure control – A preliminary survey of people with epilepsy at a safety-net hospital 自我报告的运动参与度与癫痫发作控制--对一家安全网医院癫痫患者的初步调查

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100724

Ariel Farb , Joseph Sisto , Janine Barrett , Abrar Al-Faraj , Shelby Goodson , Janice Weinberg , Jane B. Allendorfer , Myriam Abdennadher

{"title":"Self-reported exercise engagement and seizure control – A preliminary survey of people with epilepsy at a safety-net hospital","authors":"Ariel Farb , Joseph Sisto , Janine Barrett , Abrar Al-Faraj , Shelby Goodson , Janice Weinberg , Jane B. Allendorfer , Myriam Abdennadher","doi":"10.1016/j.ebr.2024.100724","DOIUrl":"10.1016/j.ebr.2024.100724","url":null,"abstract":"<div><div>Benefits of exercise on general health and wellbeing are undeniable. The International League Against Epilepsy has provided some guidance into exercise and sports for epilepsy. However, people with epilepsy are typically misinformed and restricted by fear and lack of evidence about exercise benefits in epilepsy. Our study seeks to investigate engagement in exercise in epilepsy at our center and identify potential barriers to physical activity. We conducted an anonymous survey at the Epilepsy Clinic using a clinically validated measure of exercise (IPAQ) at various levels: vigorous, moderate, and walking, and a questionnaire of 21 potential reasons for inactivity. Data were collected in REDCap. Statistical analysis was performed on SAS. We collected responses from 72 epilepsy participants between January and April 2024. Participants with controlled seizures were more likely to engage in moderate exercise compared to respondents with uncontrolled seizures. The top two general perceived barriers were having no one to exercise with and not liking exercise. Epilepsy-specific barriers were higher in respondents with uncontrolled seizures compared to those with controlled seizures, with the top two reasons being fear of “exercise-induced” seizures and lack of guidance on appropriate exercises. Our findings showed that there were more participants with controlled seizures who perform moderate exercise compared to those with uncontrolled seizures. Future studies are needed to evaluate whether exercise can have an impact on improving seizure control. Our study also highlights opportunities to educate health care providers, patients, and community members about exercise to facilitate engagement in exercise and improve epilepsy outcomes.</div></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"28 ","pages":"Article 100724"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of processing speed impairments in TLE, FLE, and GGE: Theoretical insights and clinical Implications 对 TLE、FLE 和 GGE 处理速度障碍的比较分析：理论见解和临床意义

IF 1.8

Epilepsy and Behavior Reports Pub Date : 2024-01-01 DOI: 10.1016/j.ebr.2024.100722

Adam Falah , Gavin P. Winston

{"title":"Comparative analysis of processing speed impairments in TLE, FLE, and GGE: Theoretical insights and clinical Implications","authors":"Adam Falah , Gavin P. Winston","doi":"10.1016/j.ebr.2024.100722","DOIUrl":"10.1016/j.ebr.2024.100722","url":null,"abstract":"<div><div>In this narrative review, we explore the differences in processing speed (PS) impairments among three epilepsy conditions; Temporal Lobe Epilepsy (TLE), Frontal Lobe Epilepsy (FLE) and Genetic Generalized Epilepsy (GGE) with a focus on Juvenile Myoclonic Epilepsy (JME). Despite the large body of research focusing on cognition in epilepsy, the intricacies of PS impairments in the epilepsy syndromes have not been fully explored. We investigate the cognitive profiles with focus on PS associated with each of the three conditions, and the neuropsychological methods employed. Furthermore, we evaluate PS in epilepsy within the theoretical frameworks of PS, such as the Relative Consequence Model, the Limited Time Mechanism Model, and the Neural Noise Hypothesis. We find the main challenge of PS research in epilepsy is the inconsistency of assessment methods utilized in different studies. Furthermore, PS impairments are not isolated but rather interconnected to other cognitive domains. Thus, future studies need to standardize PS assessment tools, and incorporate innovative solutions such as technology and neuroimaging techniques to further enhance our understanding of PS impairments in epilepsy.</div></div>","PeriodicalId":36558,"journal":{"name":"Epilepsy and Behavior Reports","volume":"28 ","pages":"Article 100722"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0