BANTAO JournalPub Date : 2016-12-01DOI: 10.1515/bj-2016-0023
Bengu Erkul, B. Engin, Mehmet Can Uğur, S. Ekmekçi, E. Akay, H. Akar
{"title":"Psoas as an Unusual and Overlooked Place for a Metastatic Tumor","authors":"Bengu Erkul, B. Engin, Mehmet Can Uğur, S. Ekmekçi, E. Akay, H. Akar","doi":"10.1515/bj-2016-0023","DOIUrl":"https://doi.org/10.1515/bj-2016-0023","url":null,"abstract":"Abstract We report a case of a 60-year-old hemodialysis patient who clinically mimicked psoas abscess, which was subsequently proven to be from metastatic disease seconddary to uroepithelial tumor. The patient presented with 3 weeks history of fever, weight loss and back pain. Computer tomography (CT) scan of abdomen and pelvis revealed psoas muscle infiltration not amenable to drainage by interventional radiology. Careful history to provide additional clues to the diagnosis is of paramount importance in this condition.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114668332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0010
F. Akbaş, H. Atmaca, Şennur Kose, S. Bağ
{"title":"Dialysis and Depression in the Light of Suicide Attempt with Fruits","authors":"F. Akbaş, H. Atmaca, Şennur Kose, S. Bağ","doi":"10.1515/bj-2016-0010","DOIUrl":"https://doi.org/10.1515/bj-2016-0010","url":null,"abstract":"Abstract Depression is a common morbidity seen in chronic renal failure patients but it is often underdiagnosed and undertreated. Here we present a 36-year-old male dialysis patient who had undiagnosed severe depression and attempted to commit suicide with overconsumption of fruits. Fortunately, he was saved with emergent dialysis treatment and was referred to a psychiatry clinic for treatment and observation. In the light of this case we want to point out that diagnosing and treating psychiatric problems of dialysis patients is of vital importance to prevent suicides and also to improve quality of life.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126328735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0003
I. Kostovska, Katerina Tosheska Trajkovska, S. Cekovska, G. Spasovski, D. Labudović
{"title":"Nephrin and Podocalyxin - New Podocyte Proteins for Early Detection of Secondary Nephropathies","authors":"I. Kostovska, Katerina Tosheska Trajkovska, S. Cekovska, G. Spasovski, D. Labudović","doi":"10.1515/bj-2016-0003","DOIUrl":"https://doi.org/10.1515/bj-2016-0003","url":null,"abstract":"Abstract In the last two decades a great progress was observed in understanding of podocytes, their specific structure and function identifying many specific podocyte proteins, such as nephrin and podocalyxin. Podocytes form the final barrier to plasma proteins leakage. Nephrin as a main component of the filtration diaphragm forms a physical barrier while podocalyxin as sialoglycoprotein forms an electrostatic barrier. Podocyte damage, i.e. podocytopathies and their loss through urine-podocyturia, are crucial in pathogenesis and progression of nephropathies with proteinuria as main clinical manifestation. In podocytopathies, nephrin and podocalyxin appear in the urine before proteinuria and microalbuminuria which were previously considered as earliest markers of nephropathies. Nephrinuria and podocalyxuria indicate damage of the podocytes on glomerular level and/or presence of apoptotic and necrotic podocytes in urine. These urinary markers are also important in early diagnosis of secondary nephropathies such as diabetic, lupus and hypertensive nephropathy as the most common causes of end-stage renal failure (ESRF). These markers are also important in the prediction of preeclampsia, which is the most common complication in pregnancy. In this review we elaborate in dept the main structural and functional features of podocytes and their specific proteins, nephrin and podocalyxin, summarizing the recent literature data on their importance in the early diagnosis of the most common secondary nephropathies.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127796192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0012
V. Ristovska, B. Kondov, L. Grcevska
{"title":"Different Outcome of Goodpasture Syndrome","authors":"V. Ristovska, B. Kondov, L. Grcevska","doi":"10.1515/bj-2016-0012","DOIUrl":"https://doi.org/10.1515/bj-2016-0012","url":null,"abstract":"Abstract Goodpasture syndrome is a rare autoimmune disease, with significant morbidity and mortality in young people and otherwise healthy population. Complete disease remission is possible with prompt diagnosis and treatment. We report 3 cases with Goodpasture syndrome treated at the Department of Nephrology, University Clinic of Nephrology, with different outcome. All of the patients were with similar clinical feature, with renal failure that needed treatment with hemodialysis. But results of the treatment with plasmapheresis indicate that this procedure reduces morbidity in patients with Goodpasture syndrome. The clinical course and the outcome of the disease were different. The disease is unpredictable, and the early diagnosis and start with the treatment is important for the remission.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131804365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0011
Faruk Elyiğit, H. Akar, U. Soyaltin, F. Ekinci
{"title":"A Rare Outcome Induced by Metformin Intoxication: Severe Lactic Acidosis and Hepatotoxicity","authors":"Faruk Elyiğit, H. Akar, U. Soyaltin, F. Ekinci","doi":"10.1515/bj-2016-0011","DOIUrl":"https://doi.org/10.1515/bj-2016-0011","url":null,"abstract":"Abstract Metformin is a widely used oral anti-diabetic agent that decreases insulin resistance. Lactic acidosis rarely develops with this medication. Metformin-induced hepatotoxicity has been rarely reported in the literature. We describe a patient, who presented with lactic acidosis and hepatotoxicity after ingestion of 40 pills of metformin in order to commit suicide. The most important treatment step in patients with metformin-associated lactic acidosis (MALA) is high-volume hemodialysis and hemofiltration.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122268244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0008
V. Bharambe, Hetal K Rathod, Kalpana Angadi
{"title":"Knowledge and Attitude Regarding Organ Donation among Medical Students","authors":"V. Bharambe, Hetal K Rathod, Kalpana Angadi","doi":"10.1515/bj-2016-0008","DOIUrl":"https://doi.org/10.1515/bj-2016-0008","url":null,"abstract":"Abstract Introduction. All over the world people on organ transplant waiting lists die due to shortage of donor organs. The success of organ donation program needs education of the population regarding organ donation for which healthcare professionals are most suitable. The present study was taken up to assess the knowledge and attitude of 1st, 2nd and 3rd year medical students about organ donation. Methods. A specially designed self-administered questionnaire was distributed amongst all willing 1st, 2nd and 3rd year medical students at our Medical College and later analyzed statistically. Results. A total of 157, 145 and 92 students from each year of medical education respectively gave their consent for participation in the study. Awareness regarding organ donation was found to be 98.7-100%, 69.4% claimed television as their source of information regarding organ donation and 46.7% stated that it is possible for patient to recover from brain death. The awareness regarding eye, liver, heart and kidney donations was found to be 92.4%, 87%, 87% and 97.8%, respectively. 87% of medical students were aware of need for legal supervision, and awareness regarding the existing laws was found to be 57.6%. Conclusion. Medical students had a high level of awareness and a positive attitude towards organ donation. However, knowledge regarding “brain-death”, organs and tissues donated, legislation and ethical issues was poor. A teaching intervention designed to specifically address these issues could help increase the confidence of the health-care professionals and may result finally in increased organ procurement rates.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123263441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0001
M. Gulin, Z. Puretić, J. Begovac, R. Čivljak, N. Janković, N. Bašić-Jukić, S. Rački
{"title":"Croatian Recommendations for Dialysis of HIV-Positive Patients","authors":"M. Gulin, Z. Puretić, J. Begovac, R. Čivljak, N. Janković, N. Bašić-Jukić, S. Rački","doi":"10.1515/bj-2016-0001","DOIUrl":"https://doi.org/10.1515/bj-2016-0001","url":null,"abstract":"Abstract Human immunodeficiency virus (HIV) infection may be associated with renal impairment since about 0.4% of all HIV-positive patients develop end-stage renal disease. The share of patients with HIV infection in hemodialysis centers throughout the world ranges from 0.3% to as high as 38%. In Croatia, renal replacement therapy was needed by 1% of all the HIV-positive patients from 1985 until the end of 2014. Healthcare professionals (HP) should be aware of the risks of occupational exposure to blood-borne infections in their daily work. Performing dialysis in HIV-positive patients increases the risk of exposure to HIV during the extracorporeal circulation of the infected blood. However, post-exposure prophylaxis (PEP) with effective antiretroviral drugs significantly reduces the risk of infection after occupational exposure. On behalf of the Croatian Society of Nephrology, Dialysis and Transplantation, the authors of this paper have proposed recommendations for the management of HIVpositive patients on dialysis, which aim to prevent the transmission of HIV among patients and HPs. The important recommendations include the following: 1. when the need arises, it is necessary to provide HIV-positive patients with dialysis in the vicinity of their place of residence. 2. HIV-positive patients should be dialyzed with a separate hemodialysis machine in an isolated area. Alternatively, they can be dialyzed in an area for the hemodialysis of HCV-positive and/or HBVpositive patients. 3. Specialized and trained personnel should be provided during the hemodialysis procedure, together with strict compliance with the standard precautions for the prevention of blood-borne infections. 4. There should be a good and prompt cooperation with the National Referral Center for HIV infection.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121049962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0004
Mirela Jozičić, Alen Imširović, L. Katalinic, B. Krtalic, N. Jukić
{"title":"Lung Cancer in Renal Transplant Recipients","authors":"Mirela Jozičić, Alen Imširović, L. Katalinic, B. Krtalic, N. Jukić","doi":"10.1515/bj-2016-0004","DOIUrl":"https://doi.org/10.1515/bj-2016-0004","url":null,"abstract":"Abstract Introduction. Although the incidence of malignancy has increased after solid organ transplantation, data on lung cancer in this group of patients is scarce. The aim of this study was to determine clinical characteristics and outcome of patients who developed lung cancer after renal transplantation. Methods. Among a cohort of 1658 patients who received a transplant at our institution and were followedup between 1973 and 2014, five patients developed lung cancer. We analyzed risk factors, transplantation characteristics, treatment options and survival. Results. Lung cancer was diagnosed in 5 patients (0.3%). Time to diagnosis after the transplant procedure ranged from 26 to 156 months (mean 115 months). All of them had a smoking history. Tumors were classified as IIB (20%), IIIA (40%), and IV (40%). Histological types included adenocarcinoma (80%) and there was one case of sarcomatoid carcinoma (20%). One patient had concomitant thyroid papillary carcinoma. Radiotherapy was applied in 2 patients, 2 underwent chemotherapy (erlotinib and combination of carboplatinum and etopozide in one patient each), and 2 died within one month after the diagnosis from disseminated malignant disease. Patients with stage IIIA survived 14 and 24 months after the diagnosis. The patient with sarcomatoid cancer underwent thoracotomy with a complete resection, lost his graft function and died 7 months after the diagnosis. Conclusion. Lung cancer is relatively rare malignancy in renal transplant recipients, but associated with high mortality. Smoking is a significant risk factor, thus smoking cessation should be promoted among renal transplant recipients, as well as regular screening for lung cancer.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129235898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0007
A. Balaska, D. Pistolas, M. Koukoulaki, Dimitris Alassas, S. Drakopoulos, I. Kaklamanos, G. Bonatsos, K. Birbas
{"title":"Changes in Health-Related Quality of Life in Greek Adult Patients Two Years after Successful Renal Transplantation","authors":"A. Balaska, D. Pistolas, M. Koukoulaki, Dimitris Alassas, S. Drakopoulos, I. Kaklamanos, G. Bonatsos, K. Birbas","doi":"10.1515/bj-2016-0007","DOIUrl":"https://doi.org/10.1515/bj-2016-0007","url":null,"abstract":"Abstract Introduction. This study was undertaken to compare and evaluate the heath-related quality of life (HRQOL) in Greek adult transplant recipients before and 2 years after successful renal transplantation (RT). The SF-36 survey score was used. Methods. Eighty-five Greek hemodialysis patients underwent RT at the Transplant Unit of Evangelismos General Hospital of Athens, including 44 men and 41 women (mean age 43.8 years; range 21-59 years). The scale scores of a Greek version of the SF-36 survey were compared between the transplant and the hemodialysis patients. We also examined the relationships of the scale scores with the patients′ age and the type of donor. Results. According to the SF-36 health survey, transplant recipients had better results for general health perception (p≤0.001), role-physical functioning (p≤0.01), role-emotional functioning (p≤0.01), and vitality (p≤ 0.01). In addition, the scale score of physical functioning, general health and vitality of the patients who were younger than 30 years at the time of transplantation were significantly higher than those of the patients who were older than 30 years, while the scores of bodily pain, general health, and physical functioning were significantly lower in cadaveric graft recipients compared with living-related recipients. Conclusions. The SF-36 health survey is a validated and comprehensive instrument for evaluating renal transplant patients′ HRQOL. Our data demonstrated an improvement in HRQOL in renal transplant patients 2 years after successful renal transplantation. The data also confirmed that the recipients′ age at transplantation and the type of donor were important factors affecting the HRQOL.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"496 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117124857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BANTAO JournalPub Date : 2016-06-27DOI: 10.1515/bj-2016-0005
S. Ersan, Senem Ertilav, A. Çelik, A. Sifil, C. Çavdar, M. Unlu, S. Sarıoğlu, H. Gulay, T. Camsari
{"title":"Prevalence and Causes of Proteinuria in Kidney Transplant Recipients: Data from a Single Center","authors":"S. Ersan, Senem Ertilav, A. Çelik, A. Sifil, C. Çavdar, M. Unlu, S. Sarıoğlu, H. Gulay, T. Camsari","doi":"10.1515/bj-2016-0005","DOIUrl":"https://doi.org/10.1515/bj-2016-0005","url":null,"abstract":"Abstract Introduction. Proteinuria after renal transplantation increases the risk of graft failure and mortality. The aim of the study was to determine the prevalence and causes of proteinuria in kidney transplant recipients. Methods. All kidney transplant recipients followed up in our clinic were included in the study. As a center protocol 24-hour urine collections were used to quantify protein excretion with 3-month intervals posttransplantation during the first year, and yearly thereafter. The etiology of chronic kidney disease and demographic characteristics of the study group were obtained from outpatient records. Data regarding the immunosuppressive regimens used, 24-hour proteinuria levels and creatinine clearences, new-onset hypertension, new-onset diabetes mellitus, rejection episodes, infections like cytomegalovirus (CMV) and polyoma (BK), and biopsy findings were noted. Results. A total of 260 kidney transplant recipients (97 females, mean age 42.3±12.3 years) were evaluated. Median follow-up period was 36 months; 137 of all transplantations were from living donors. Mean age of donors was 42.7±15 years and 133 were female. Proteinuria with protein excretion ≥300 mg/d was present in 35.4% of patients. The most common cause of biopsy-proven proteinuria was transplant-specific conditions (acute rejection, and borderline changes). Conclusion. The prevalence of proteinuria was 35.4%. The transplant-specific diagnoses were the most likely causes. Even in nonnephrotic ranges it was associated with decreased graft survival.","PeriodicalId":365549,"journal":{"name":"BANTAO Journal","volume":"158 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123047571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}