IP Journal of Diagnostic Pathology and Oncology最新文献

{"title":"Serous papillary cystadenofibroma of ovary: A rare entity diagnosed on frozen section","authors":"Shushruta Mohanty, Lipika Behera, Chaitali Patnaik, Deepika Mishra, Shwetambari Acharya","doi":"10.18231/j.jdpo.2022.047","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.047","url":null,"abstract":"Ovarian cystadenofibroma are rare slow growing benign epithelial ovarian neoplasms. It usually occurs as solid and cystic component. Most of the tumours are asymptomatic and detected incidentally during abdominal ultrasound for some other purpose. They may mimick malignant neoplasm with their gross appearance and imaging modalities. So a diagnosis of serous papillary cystadenofibroma of ovary on frozen section can save the patient from unwanted extensive surgery. We here in discuss a case of serous papillary cystadenofibroma of ovary in a 45 year old multipara that was diagnosed initially on frozen section and later confirmed on histopathology, thus highlighting the role of frozen section in diagnosis of intraoperative ovarian neoplasms.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125874046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of absolute eosinophil count in covid-19 patients","authors":"Kunal Gaur, S. Natarajan, Mohini Gupta","doi":"10.18231/j.jdpo.2022.041","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.041","url":null,"abstract":"Coronavirus 2 (SARS-CoV-2) has created worldwide healthcare problems and strained health resources. Reduced eosinophil levels are one of the unique discoveries that have been discovered in COVID 19 recently. The goal of this study is to establish the association between the mortality in COVID-19 with eosinopenia by retrospectively analysing data from fifty COVID-19 patients with varying illness severity, including moderate, severe, and critically ill. Fifty patients taken from Sree Balaji Medical College and Hospital, of which twenty five critically ill patients and twenty-five having moderate to severe COVID-19 infection at hospital admission were enrolled. After being admitted to the hospital, information on the patient's medical history, clinical symptoms, CT severity score, and outcomes were taken from their medical records. The study concluded that Compared to individuals with moderate and severe disorders, critical illness patients' eosinophil levels were much lower. Eosinophil levels gradually decreasing was found to be a separate factor which has been associated with mortality. Patients with COVID-19 who have eosinopenia have a considerably higher mortality rate. These values can be obtained by simple means such as obtaining peripheral blood, so this is an easy and an effective indicator in monitoring these patients.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132994549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primitive neuroectodermal tumor of kidney in elderly -A case series with review of literature","authors":"K. Kavitha, G. Kottangal, Shehla Basheer Kollathodi, Shalini Kuruvila, L. Madhavan, Surdas Radhakrishnan","doi":"10.18231/j.jdpo.2022.051","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.051","url":null,"abstract":"Primitive neuroectodermal tumor of the kidney (PNET) is a very rare and highly aggressive tumor commonly seen in young adolescents. These tumors are rare in patients over 40 years. Reports of renal PNET in elderly patients over 60 years are even rarer.We report three cases of renal PNET in adult patients diagnosed over a period of three years. Among the three patients, two were above 60 years of age and the third patient was a 39-year-old male. All the three patients had extensive venous thrombosis at the time of presentation. One of the patients succumbed to death in the immediate post-operative period and the other two received chemotherapy.Renal PNET owing to its rare occurrence in middle-aged and elderly poses a diagnostic challenge to the pathologist. The clinical and radiological findings have limitations in the accurate diagnosis. Thorough morphological evaluation along with immunohistochemistry and cytogenetic analysis help in arriving at a correct diagnosis. An accurate diagnosis is crucial for the initiation of proper treatment.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129663956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Juvenile fibroadenoma of the breast","authors":"S. Jagtap, Swati S. Jagtap, Nidhi Goswami, Neha Babasaheb Desai","doi":"10.18231/j.jdpo.2022.043","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.043","url":null,"abstract":"Juvenile fibroadenoma is a rare variant of fibroadenoma and is characterized by rapidly enlarging, painless, and unilateral masses. We presents a case of juvenile fibroadenoma of the breast in a 14 year old girl, presented with rapidly growing mass in the right breast of four months duration. On local examination a solitary, firm, mobile, unilateral, non-tender mass was felt in the upper and lower outer quadrant of the right breast, measuring 6.5 x 4.1 x 3.5cm. The overlying skin was normal. There was no axillary lymphadenopathy. The sonomammography of the right breast showed a single, oval, hypoechoic, well circumscribed mass lesion with cleft like spaces features suggestive of complex fibroadenoma BIRADS IV a. On fine niddle aspiration cytology showed sheets of hyperplastic benign ductal epithelial cells with myoepithelial cells and a background of benign bipolar nuclei and blood, without inflammatory cells. It was suggestive of fibroadenoma. She underwent right lumpectomy with breast conservation. We received right breast lumpectomy specimen. On gross showed a well-circumscribed, grey white, firm mass m 6.3 x 4.1 x 3.2 cm. On histologic features reported as juvenile fibroadenoma right breast. The postoperative period was uneventful and she recovered well and advise regular follow up. Juvenile fibroadenomas are rare benign breast tumors that should be distinguished from other masses of breast. Herewith we are presenting case of Juvenile fibroadenoma for its clinical, radio imaging, pathological features and management.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124912506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratoryepithelialadenomatoid hamartoma (REAH)","authors":"Shushruta Mohanty, Lipika Behera, C. Pattnaik, S. Acharya, Deepika Mishra, S. R. Jena","doi":"10.18231/j.jdpo.2022.037","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.037","url":null,"abstract":"","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115786565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of role of umbilical cord anomalies in fetal death-An institutional experience","authors":"Fakeha Begum, P. Mounika, M. Pavane, C. Ramya","doi":"10.18231/j.jdpo.2022.042","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.042","url":null,"abstract":"Umbilical cord plays pivotal role in development and well being of fetus. Any abnormality in the umbilical cord can affect the viability of the fetus. In spite of presence antenatal diagnostic modalities still fetal autopsy plays a vital role in identification and confirmation of the abnormalities which lead to intrauterine fetal death. To check for incidence of variety of cord abnormalities in perinatal fetal deaths. It is a retrospective observational study of 26 cases of perinatal deaths due to cord abnormalities taken from Jan 2013 to July 2021 in tertiary care center. In the study 26 cases of fetal autopsy were included over a period of nine years. Mean maternal age was 26 years. 12 cases (44.3%) were of vessel number defects. In which 11 were two vessel cords and the other was 5 vessel cord, 14 cases showed short cord. 8 cases showed normal cord length. 4 cases showed long cords. True knots were seen in one case. 3 cases (28%) were involving stenosed cords. and 5 cases (28.4%) were of supercoiling 3 twisted cords. Maternal co-morbidities were present in 3 cases.Umbilical cord anomaly is a major stress factor for fetus playing a key role in feto-maternal perfusion. Cord abnormalities can be clinically insignificant or can be severe leading to foetal death. The present study reemphasizes the importance of umbilical cord and its impact on wellbeing of foetus. Thus there is need to develop special and exclusive antenatal screening for umbilical cord abnormalities needs further research.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128954180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sinus histiocytosis with massive lymphadenopathy (Rosai Dorfman Disease) - A rare case of isolated axillary lympadenopathy diagnosed on FNAC","authors":"Vineet Banga","doi":"10.18231/j.jdpo.2022.045","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.045","url":null,"abstract":"Rosai-Dorfman disease (Sinus Histiocytosis with Massive Lymphadenopathy) is a rare disorder characterized by overproduction (proliferation) and accumulation of histiocytes in the lymph nodes of the body causing lymphadenopathy, most often involving neck. In some cases, abnormal accumulation of histiocytes may occur in other areas of the body besides the lymph nodes (extra nodal). These areas include the skin, central nervous system, kidney, and digestive tract. The case is being reported as a rare case involving isolated axillary lymph node and was diagnosed on FNAC.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129706171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nevus lipomatosis cutaneous superficialis (NLCS) - A case series of four cases of this rare dermal anomaly in a tertiary care centre","authors":"N. Gupta, M. Puri","doi":"10.18231/j.jdpo.2022.050","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.050","url":null,"abstract":"Nevus lipomatosis cutaneous superficialis is a rare benign idiopathic dermal anomaly having a good prognosis after excision. Here we are reporting a case series of four cases of nevus lipomatosis cutaneous superficialis to raise recognition of this rare disease.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124656170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of complete blood count parameters pre and post transfusion of packed red blood: A meta-analytic study in a tertiary care hospital","authors":"A. Vaithy K, K. Sri, Shanmugasamy, S. S","doi":"10.18231/j.jdpo.2022.020","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.020","url":null,"abstract":"The clinical condition of anaemia is defined as reduction below normal limits of the total circulating red cell mass. It is measured by the reduction in packed red cell volume or reduction in haemoglobin concentration of blood. Patients with hemoglobin below 6 gm/dl usually require transfusion therapy. In stabilized patients with hemoglobin values between 6 and 10 gm/dl, the decision whether to transfuse is based on an evaluation of clinical status. The present study comprised of 140 Anaemic patients who received packed red cell transfusion. The study was analyzed for a period of one year. Haematological parameters – complete blood counts were collected by running anticoagulated blood in automated haematology analyser before and after transfusing the blood units. Peripheral smear by using Leishman’s stain. Reticulocyte count by using new methylene blue.Of total 140 patients, 45(34.6%) of patients were clinically diagnosed as iron deficiency anaemia followed by 43(33.1%) anaemia of chronic disease patients, 18(13.8%) of anaemia of chronic kidney disease, 20(15%) of anaemia of liver disease, 10(7.7%) of dimorphic anaemia (anaemia of combined deficiency) and 4(3.1%) of anaemia in hypersplenism.Iron deficiency anaemia is the most common disease group in the present study followed by anaemia of chronic disease. Anaemia is more prevalent in the female population with M:F ratio of 4:5. Particularly iron deficiency anaemia is more prevalent among females with M:F ratio of 1:3. After one unit of packed red cell transfusion the mean increase in Hb in IDA was 1.106gm/dl, in anaemia of ACD was 0.922gm/dl, in anaemia of CKD was 1.015gm/dl, in anaemia of liver disease was 0.614gm/dl in anaemia of combined deficiency was 0.925gm/dl and in hypersplenism was 0.367 gm/dl. From this background the present study concludes that before planning transfusion in anaemic patients, accurate clinical assessment and work up for type of anaemia is essential. After transfusion of one unit of packed red cells in chronic anaemia patients,. In all the types of anaemia studied, the mean increase in Hb and PCV values were statistically more significant (Pvalue<0.05) than other parameters. Hence Hb and PCV can be taken as valuable parameters to monitor the post transfusion outcome.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116002682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myxofibrosarcoma of neck: A rare case","authors":"Arun Hn, Chaitra, Srinivas Nm, Ravi Savasere","doi":"10.18231/j.jdpo.2022.024","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.024","url":null,"abstract":"Myxofibrosarcoma (MFS) is commonly seen among elderly patients, usually sixth to eighth decade of life. Most of these tumours arise in the extremities (lower limbs > upper limbs) and are less commonly seen on the Trunk, Head and Neck, Retroperitoneum and Pelvic areas. The World Health Organization (WHO) defines MFS as the malignant fibroblastic neoplasm characterized by cellular pleomorphism, variably prominent myxoid stroma, and prominent elongated, thin-walled stromal blood vessels. Head Neck MFS is rare site of occurrence with 19 cases reported worldwide till date, described subsites being Maxillary sinus, Infra Temporal fossa, Pterygopalatine fossa, or Parotid gland. The Surgical wide local excision is the main modality of treatment for Non metastatic stage followed by Adjuvant Radiotheraphy.We are presenting a young adult male, presenting with Asymptomatic progressive neck mass, predominantly in posterior triangle distorting upper Aerodigestive tract anatomy. The Diagnosis of MFS done with MRI imaging of neck, Trucut biopsy and CECT scan thorax. With the anticipation of difficult intubation, Broncoscopic directed intubation is planned and done. The surgical wide resection amounted in excision of Sternomastoid, IJV, SAN and part of posterior triangle bed muscles for getting margin free status. The Histopathology showed spindle cells with Myxoid stroma, areas of necrosis with circumferential free margins, along with IHC showed positive for vimentin and CD34 with diagnosis as High Grade Myxofibrosarcoma. Post op patient was adviced Adjuvant Radiotheraphy.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122196646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}