IP Journal of Diagnostic Pathology and Oncology最新文献_第7页

Hibernoma-A rare tumor on rare site 冬眠瘤是一种罕见部位的罕见肿瘤

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.066

Himachal Mishra, Manika Alexander

{"title":"Hibernoma-A rare tumor on rare site","authors":"Himachal Mishra, Manika Alexander","doi":"10.18231/j.jdpo.2022.066","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.066","url":null,"abstract":"Hibernoma is a rare benign tumor that originates from brown fat. Hibernoma is thought to arise from areas containing residual brown fat like- the interscapular area, axilla, neck, chest, abdominal cavity, and retroperitoneum. The incidence of this rare tumor has very rarely been reported to occur over the forehead. Being a benign tumor, no association of malignant transformation or metastasis has been reported. A 23-year-old male presented with a complaint of a painless non-progressive swelling over the forehead for the past 6 months. On examination, the swelling was 2x2 cm, soft, mobile, non-tender, and non-pulsatile with no skin changes. FNAC did which shows sheets and clusters of adipocytes with abundant foamy cytoplasm and reported as “Hibernoma”. The patient has been asked to follow up and for the last 1 year, the tumor is still non-progressive with no pressure symptoms and hence has not undergone surgery. Hibernoma is a rare benign tumor of brown fat tissue which constitutes only 1.6% of benign lipomatous tumors but their actual prevalence is still unknown. This tumor very rarely may occur in the forehead area although incidence over the forehead has rarely been reported. Since this tumor is slow growing, painless non-progressive; it mostly presents as an asymptomatic tumor. It has to be included in the differential diagnosis of adipocyte-containing tumors to prevent false treatment.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117262221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary vaginal villous adenoma – A rare case report 原发阴道绒毛腺瘤1例报告

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.060

Shilpa Mishra, R. Patkar, A. Neelakantan

引用次数: 0

Rare cytogenetic abnormalities in MDS evolving from fanconi anemia-A case report 范可尼贫血演变为MDS的罕见细胞遗传学异常- 1例报告

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.059

Nidhi Rajendra, Subbaiah Ramanathan, V. Ashok, Srivalli BS

引用次数: 0

Concomitant squamous cell carcinoma and actinomycosis—An unique and rare occurrence 伴随鳞状细胞癌和放线菌病-一种独特和罕见的发生

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.061

Sameer Kadam, Hoogar MB, A. Valand, Vaishali Bhonsale, Kirti Pardesi, Nakul Y. Sampat

{"title":"Concomitant squamous cell carcinoma and actinomycosis—An unique and rare occurrence","authors":"Sameer Kadam, Hoogar MB, A. Valand, Vaishali Bhonsale, Kirti Pardesi, Nakul Y. Sampat","doi":"10.18231/j.jdpo.2022.061","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.061","url":null,"abstract":": Actinomycosis of the oral cavity is not common, though actinomyces species often occur as normal commensals in the oral cavity. They gain entry into deep tissue to cause infection and consequent tissue damage whenever there is damage to the oral mucosa by injury or infection or neoplastic process. The case being discussed here is of a male, aged 62 years, who presented with an ulcero-proliferative lesion over left buccal mucosa. A punch biopsy was carried out on the lesion. Histopathology laboratory received three gray-white tissue pieces. Histological examination of the tissue pieces revealed features of moderately to poorly differentiated squamous cell carcinoma. Few colonies of radiating filamentous structures reminiscent of colonies of actinomyces species were noted. The sections were further stained with relevant stains for filamentous bacteria such as Periodic Acid Schiff (PAS) stain which confirmed the colonies of Actinomyces spp. The case being submitted here is an unique and relatively rare finding of concomitant squamous cell carcinoma and oral actinomycosis with only few cases being reported in publish English medical literature.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127495118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

An unusual visitant in gastric biopsy- A report of two rare cases 胃活组织检查中不寻常的来访者——报告两例罕见病例

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.062

Vallalkani KN, Sumithra A, H. Volga

引用次数: 0

Chondrosarcoma of the great toe clinically mimicking osteoclastoma-An unusual presentation 临床模拟破骨细胞瘤的大脚趾软骨肉瘤-一种不寻常的表现

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.064

K. Akhtar, Saman Usmani, Fatma Lubna, Sarah Irfan

引用次数: 0

Survivin and p53 expression in benign and malignant lesions of breast Survivin和p53在乳腺良恶性病变中的表达

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.054

S. Raj, Shristi Soni, D. Aden, Alka Yadav, Sameeksha Raj

{"title":"Survivin and p53 expression in benign and malignant lesions of breast","authors":"S. Raj, Shristi Soni, D. Aden, Alka Yadav, Sameeksha Raj","doi":"10.18231/j.jdpo.2022.054","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.054","url":null,"abstract":"Breast cancer is the most common malignancy in women, accounting for 14 % of all cancers in India; it accounts for < 1% of all cancer cases in men. Breast cancer is the leading cause of death worldwide. The study aims to assess the expression of p53 and Survivin in Fibroadenoma and Invasive carcinoma of no special type and its prognostic importance.A total number of 75 cases are included in the study, out of which 34 are reported by two histopathologists as invasive carcinoma NST (ductal) and 41 reported as Fibroadenoma. All the cases included in the study are females. Immunohistochemistry for p53 and Survivin performed in both the groups with positive and negative controls. Cytoplasmic or nuclear IHC expression for Survivin is considered to be positive. Whereas, nuclear positivity is considered for p53. A semi quantitative scoring system performed consisting of intensity and % of positive cells. The expression of Survivin and p53 is found to be high in IDC, 79% and 85% respectively. The correlation is found to be significant (p value = 0.002, Spearman Rho correlation). However, the expression of Survivin is seen in one third of all the cases of Fibroadenoma (37.5%) and p53 expression is expectedly low, seen in 12% cases. Over expression of Survivin in IDC patients compared to benign cases is found to be correlated with p53 expression. Though Survivin is likely to contribute to apoptosis resistance, its expression is found to confer resistance to chemotherapy and radiotherapy in IDC. Henceforth, Survivin over expression along with p53 in invasive breast carcinoma defining overall poor prognosis and low survival rates.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123485587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathological study of lesions of appendix 阑尾病变的组织病理学研究

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.055

S. Khan, Y. Momin, A. Gosavi, A. Waje

{"title":"Histopathological study of lesions of appendix","authors":"S. Khan, Y. Momin, A. Gosavi, A. Waje","doi":"10.18231/j.jdpo.2022.055","DOIUrl":"https://doi.org/10.18231/j.jdpo.2022.055","url":null,"abstract":"The human appendix is a supposedly funtionless organ, but can cause morbidity and mortality because it is likely to be infected. Acute Appendicitis being the most common surgical emergency. Appendicectomy specimens from suspected acute appendicitis often appear macroscopically normal but histological analysis reveal a more sinister underlying pathology.A three year study was performed to determine the incidence of various non-neoplastic and neoplastic lesions of appendix. To study the histopathology of various lesions of appendix.It is a retrospective study for a period of three years at Tertiary care hospital. The histopathological reports and clinical details were collected and slides were reviewed and evaluated. Special stains were used wherever required.The study included 1092 cases of lesions of appendix. The commonest lesion was chronic non-specific appendicitis (48.27%) followed by acute appendicitis with (47.80%). Other non neoplastic lesions found were fibrous obliteration of appendix (2.10%), chronic appendicitis with Enterobius vermicularis infestation (0.83), tuberculosis (0.18), xanthogranulomatous appendicitis (0.09%) and amoebic appendicitis (0.09%). Neoplastic lesions seen were low grade mucinous neoplasm (0.18) and serrated adenoma (0.09). Chronic non-specific appendicitis is the commonest appendiceal lesion. The various lesions of appendix clinically present as acute or chronic appendicitis but histology reveals the true nature of the lesion and hence remains the gold standard method.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131981887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sino-nasal and pharyngeal mass- Immunohistochemistry cuts the gordian knot 鼻咽肿物-免疫组化能解决棘手的问题

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.057

Geethamala K, M. Jadhav, Sneha K, Nirmala BL, R. Haravi, Shirish Patil

引用次数: 0

Characteristic yet unusual presentation of an odontogenic myxoma in the anterior mandible 下颌前牙源性黏液瘤的特征性但不寻常的表现

IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-01-15 DOI: 10.18231/j.jdpo.2022.065

S. Sachdev, Kavita Wadde, Asha Chowdhar, Prachi Mathe

引用次数: 0