{"title":"Antisocial and Borderline Personality Disorders in the Emergency Department: Conceptualizing and Managing “Malingered” or “Exaggerated” Symptoms","authors":"V. Hong, Loreen F Pirnie, A. Shobassy","doi":"10.1007/s40473-019-00183-4","DOIUrl":"https://doi.org/10.1007/s40473-019-00183-4","url":null,"abstract":"","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"6 1","pages":"127 - 132"},"PeriodicalIF":1.7,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00183-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44333715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jill Del Pozzo, Christina Athineos, Taylor Zar, Lisa N. Cruz, Christopher M King
{"title":"Frustrative Non-reward and Lab-Based Paradigms for Advancing the Study of Aggression in Persons with Psychosis","authors":"Jill Del Pozzo, Christina Athineos, Taylor Zar, Lisa N. Cruz, Christopher M King","doi":"10.1007/s40473-019-00173-6","DOIUrl":"https://doi.org/10.1007/s40473-019-00173-6","url":null,"abstract":"","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"6 1","pages":"27-36"},"PeriodicalIF":1.7,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00173-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41637476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Remediation of Visual Processing Impairments in Schizophrenia: Where We Are and Where We Need to Be","authors":"D. Demmin, Samantha I. Fradkin, S. Silverstein","doi":"10.1007/s40473-019-00171-8","DOIUrl":"https://doi.org/10.1007/s40473-019-00171-8","url":null,"abstract":"","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"6 1","pages":"13-20"},"PeriodicalIF":1.7,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00171-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44848316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mitochondrial Dysfunction in Alzheimer’s Disease and Progress in Mitochondria-Targeted Therapeutics","authors":"Padraig J. Flannery, E. Trushina","doi":"10.1007/s40473-019-00179-0","DOIUrl":"https://doi.org/10.1007/s40473-019-00179-0","url":null,"abstract":"","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"1 1","pages":"1-15"},"PeriodicalIF":1.7,"publicationDate":"2019-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00179-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46885187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maju Mathew Koola, Samir Kumar Praharaj, Anilkumar Pillai
{"title":"Galantamine-Memantine Combination as an Antioxidant Treatment for Schizophrenia.","authors":"Maju Mathew Koola, Samir Kumar Praharaj, Anilkumar Pillai","doi":"10.1007/s40473-019-00174-5","DOIUrl":"https://doi.org/10.1007/s40473-019-00174-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>The objective of this article is to highlight the potential role of the galantamine-memantine combination as a novel antioxidant treatment for schizophrenia.</p><p><strong>Recent findings: </strong>In addition to the well-known mechanisms of action of galantamine and memantine, these medications also have antioxidant activity. Furthermore, an interplay exists between oxidative stress, inflammation (redox-inflammatory hypothesis), and kynurenine pathway metabolites. Also, there is an interaction between brain-derived neurotrophic factor and oxidative stress in schizophrenia. Oxidative stress may be associated with positive, cognitive, and negative symptoms and impairments in white matter integrity in schizophrenia. The antipsychotic-galantamine-memantine combination may provide a novel strategy in schizophrenia to treat positive, cognitive, and negative symptoms.</p><p><strong>Summary: </strong>A \"single antioxidant\" may be inadequate to counteract the complex cascade of oxidative stress. The galantamine-memantine combination as \"double antioxidants\" is promising. Hence, randomized controlled trials are warranted with the antipsychotic-galantamine-memantine combination with oxidative stress and antioxidant biomarkers in schizophrenia.</p>","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"6 2","pages":"37-50"},"PeriodicalIF":1.7,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00174-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10482705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa A Bartolomeo, Molly A Erickson, Lauren E Arnold, Gregory P Strauss
{"title":"FRONTAL ALPHA ASYMMETRY IN YOUTH AT CLINICAL HIGH-RISK FOR PSYCHOSIS.","authors":"Lisa A Bartolomeo, Molly A Erickson, Lauren E Arnold, Gregory P Strauss","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose of the review: </strong>Negative symptoms are highly predictive of whether individuals at clinical high-risk (CHR) develop a psychotic disorder. However, little is known about pathophysiological mechanisms underlying negative symptoms during this period. The current study examined neurophysiological mechanisms underlying negative symptoms in CHR individuals using electroencephalography frontal alpha asymmetry power, a biomarker of approach and avoidance motivation.</p><p><strong>Recent findings: </strong>People with schizophrenia display abnormal patterns of frontal alpha asymmetry indicative of reduced approach motivation. However, It is unknown whether similar abnormalities occur in CHR youth that predict negative symptoms.</p><p><strong>Summary: </strong>Results indicated that CHR and healthy controls did not differ in frontal alpha asymmetry scores. However, in CHR youth, frontal alpha asymmetry was inversely correlated with the motivation and pleasure dimension of negative symptoms, which was accounted for by mood symptoms. Findings suggest that depression contributes to reduced approach motivation in CHR youth that manifests clinically as negative symptoms.</p>","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":" ","pages":"21-26"},"PeriodicalIF":1.7,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922025/pdf/nihms-1528825.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37475216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa A. Bartolomeo, Molly A. Erickson, L. Arnold, G. Strauss
{"title":"Frontal Alpha Asymmetry in Youth at Clinical High Risk for Psychosis","authors":"Lisa A. Bartolomeo, Molly A. Erickson, L. Arnold, G. Strauss","doi":"10.1007/s40473-019-00172-7","DOIUrl":"https://doi.org/10.1007/s40473-019-00172-7","url":null,"abstract":"","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"6 1","pages":"21-26"},"PeriodicalIF":1.7,"publicationDate":"2019-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00172-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43611296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Remote Monitoring for Understanding Mechanisms and Prediction in Psychiatry","authors":"G. Gillett, K. Saunders","doi":"10.1007/s40473-019-00176-3","DOIUrl":"https://doi.org/10.1007/s40473-019-00176-3","url":null,"abstract":"","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"6 1","pages":"51-56"},"PeriodicalIF":1.7,"publicationDate":"2019-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40473-019-00176-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41516844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}