Journal of Current Science and Technology最新文献

{"title":"Therapeutic Potential of Topical Cannabis for the Treatment of Psoriasis: A Preliminary Clinical Evaluation of Two Different Formulations","authors":"Thanvisith Charoenying, Kamolrak Lomwong, P. Boonkrong, Wantika Kruanamkam","doi":"10.59796/jcst.v14n1.2024.6","DOIUrl":"https://doi.org/10.59796/jcst.v14n1.2024.6","url":null,"abstract":"The aim of this study is to investigate the potential therapeutic benefits of using cannabis-enriched topical cream containing of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), either alone (THC:CBD) or in combination with a polyherbal formulation for treating psoriasis. To evaluate the efficacy and safety of both formulations, a crossover, randomized, single-blinded study was conducted on 20 volunteers who were monitored for key indicators such as PASI score, PDI, DLQI, and blood profile. The present study involved two eight-week treatment periods with each formulation, separated by a two-week washout period. The results showed that the group using the cannabis cream comprising of THC:CBD alone experienced a significant reduction in PASI score after four weeks over the course of the 8-week study. Furthermore, the combination of THC:CBD and the polyherbal formulation was found to be more effective in reducing disease severity and improving patient quality of life. No significant adverse reactions were observed, and there was no difference in blood profile before and after treatment. These findings indicate that both topical formulations are safe and effective for treating psoriasis, with the combined formulation showing greater potential than using topical cannabis alone.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"54 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138597507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence of Visual Impairment of the Elderly at University Eye Clinic","authors":"W. Jenchitr, Patchapicha Yokkampon, Patcharin Ploysit, S. Ausayakhun","doi":"10.59796/jcst.v14n1.2024.9","DOIUrl":"https://doi.org/10.59796/jcst.v14n1.2024.9","url":null,"abstract":"The purpose of this study is to determine the prevalence and causes of visual impairment of the elderly who came to Rangsit University Eye Clinic for eye services in 2020-2021. Medical charts of elderly patients aged 60 years and older were retrospectively reviewed. Demographic data collected included age, gender, and underlying diseases. Data on refraction by optometrists and eye examination by ophthalmologists were collected. The Visual impairment was categorized using WHO definitions. The study included 1,452 patients aged 60 years and older with a mean age of 69.6 ± 8.09 years (range 60 to 110 years). Visual impairment was classified using presenting visual acuity (PVA) and best corrected visual acuity (BCVA). The prevalence of bilateral blindness and bilateral moderate and severe visual impairment (MSVI) using PVA were 6.20% and 69.56% respectively. When using BCVA, bilateral blindness, and bilateral MSVI were 0.69% and 11.02% respectively. Bilateral blindness did not increase with aging (p =0.125) and no gender difference (p=0.521) when using PVA. If using BCVA, bilateral MSVI did not increase with aging (p=0.920) and no gender difference (p=0.242) For eye diseases causing MSVI, were cataract, glaucoma, retinal detachment, epiretinal membrane, diabetic retinopathy and age-related macular degeneration, branch retinal vein occlusion. The emerging cause of bilateral blindness and bilateral MSVI were myopic macular degeneration. In conclusion, this study investigated the prevalence of visual impairment in the elderly population at the University Eye Clinic. Since visual impairment from these diseases can be prevented or treated, planning for eye health promotion and prevention, with the involvement of appropriate eye personnel for screening, is therefore necessary to prevent avoidable visual impairment.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"5 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138597195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decision-Making Experiences to use Medicinal Cannabis: Perspectives from Patients with Knee Osteoarthritis and Their Care Providers.","authors":"Wijitra Sena, P. Kessomboon, Malinee Pisutthigoson, Wongjan Poolpoem, Thanamet Thaenkham, Khachornsak Seevathee","doi":"10.59796/jcst.v14n1.2024.4","DOIUrl":"https://doi.org/10.59796/jcst.v14n1.2024.4","url":null,"abstract":"This study investigated the experience of making a decision to use medicinal cannabis among patients with knee osteoarthritis and their care providers. This qualitative research used a phenomenological approach to collect information by purposive sampling. Informants included 7 patients with knee osteoarthritis and 18 care providers in Khon Kaen municipality. Data were collected from June until December 2021using in-depth interviews, field records and participatory observation. After 6 months of data collection, the modified Colaizzi’s seven-step method was used for data analysis. The results show that the content from all informants can be categorized into 7 distinct themes about their decision-making on using medicinal cannabis (MC): 1) The needs for MC: Recognizing the painful nature of osteoarthritic pain and the limited treatment options available 2) Beliefs and attitudes towards MC with two sub-themes identified as 2.1) Belief in the MC’s efficacy that denotes informants’ positive perception and 2.2) Attitudes towards MC that show doubt, hesitation, or lack of confidence in MC’s effectiveness 3) Evidence on efficacy and safety of MC products: Considering cannabis as a viable treatment option 4) Trustworthiness of information and communication about MC. 5) Influence of other people: Three key influencers in the decision-making process including 5.1) Patients themselves 5.2) Friends and peers 5.3) Doctors and healthcare professionals 6) Legitimacy status of MC and 7) Product designs regarding forms of therapeutic use. The findings yielded 7 distinct themes concerning the decision to use medicinal cannabis (MC). The most important component is the need for pain relief among knee osteoarthritis patients. They clearly need MC for relieving their symptoms. Evidence on efficacy and legalization status of MC are also the main factors, while other 4 components are less important or not the vital factors for making decision on MC’s utilization. Policies on MC need to address these factors.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"47 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138597788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated Inverse Kinematics Configuration Selection for Path Planning of a 6-DOF Robot","authors":"Xuan-Vinh Nguyen, Ngoc-Lam Nguyen","doi":"10.59796/jcst.v14n1.2024.10","DOIUrl":"https://doi.org/10.59796/jcst.v14n1.2024.10","url":null,"abstract":"This article presents an automated technique for selecting suitable inverse configurations for the path planning of robots with six degrees of freedom (6 DOF). Traditionally, robots were limited to a single fixed configuration for movement, but now there's a growing need for robots that can adapt to different situations, especially in unknown environments. In this study, we introduce an innovative approach designed to assist a small industrial robot known as AKB-IRV1. This approach helps the robot determine and automatically select the most suitable configuration to move, which is essential for effective path planning. We simplify a complex problem related to how the robot's joints work through geometric analysis, breaking it down into two stages: calculation and selection of the best joint angles for movement. We also use computer simulations to assess the robot's workspace, considering joint angles as constraints. Our findings reveal that taking joint angles into account significantly reduces the robot's effective workspace. We also present a method for the robot to automatically choose the right configuration when planning its path, especially in uncertain situations. This ability allows the robot to change its configuration as needed, aligning with the goal of minimizing configuration changes. This method has promising applications for intelligent robots operating in unfamiliar environments.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"90 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138596116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applying Decision Tree and Bibliometric Analysis: The Analysis of Digital Governance Determinants","authors":"Benjawan Kunviroteluck, Alisa Kongthon, Patipan SaeLim","doi":"10.59796/jcst.v14n1.2024.8","DOIUrl":"https://doi.org/10.59796/jcst.v14n1.2024.8","url":null,"abstract":"Digital governance plays a crucial role in leading organizations in their digital transformation process. This paper aims to explore the analysis of digital governance determinants through the application of decision tree and bibliometric analysis techniques. Understanding these factors can help organizations in developing effective digital governance initiatives and strategies. Bibliometric analysis is utilized to identify new trends and overall research landscape of digital governance. K-means clustering and decision tree are then used to identify key determinants of effective digital governance. Our results show that leadership is the most initial important factor. In addition, to enhance digital governance to the highest level, organizational culture that is driven from the leader is also another important factor. The findings of this study yield insights for practitioners and managers who seek to improve their digital governance practices.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"60 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138596202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive and Multifunctional Wool Textiles Finishing with Diospyros mollis Griff. Extract","authors":"Pisutsaran Chitichotpanya, Nattaya Vuthiganond, Thitirat Inprasit, Pimnara Chutasen","doi":"10.59796/jcst.v14n1.2024.3","DOIUrl":"https://doi.org/10.59796/jcst.v14n1.2024.3","url":null,"abstract":"Due to the sudden pandemic outbreak, there is a substantial demand for antimicrobial textiles for health and hygiene. Natural dyeing with plant sources has been proven to be an excellent eco-friendly method for producing healthcare textiles. In this study, Diospyros mollis Griff. extract was applied to the simultaneous dyeing and multi-functionalization (antibacterial activity and UV-protection) of wool fabrics. Response surface methodology was applied to optimize the treatment procedure and assess parameter interactions. The optimal result was achieved when dyeing at pH 4, dye concentration 25 g/L, temperature 88°C, and time 95 min. The dyed fabrics had good antibacterial activity against both E.coli and S.aureus (bacterial colony reduction > 90%), with E.coli being more pronounced. The UV protection factor (UPF) also reached the maximum (40+) level, demonstrating their superior UV protection. The finished wools are black, with high color strength (K/S > 9), good light and washing fastness, and fair to good crocking fastness. Thus, Diospyros mollis Griff. fruit extract can be used as a new bioactive agent for multifunctional textiles, as well as simultaneous black coloring.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138597000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis for augmented decision-making applications using deep learning models","authors":"P. Durga, S. Karthikeyan","doi":"10.59796/jcst.v13n3.2023.2273","DOIUrl":"https://doi.org/10.59796/jcst.v13n3.2023.2273","url":null,"abstract":"Now a days decision-making plays a significant role in various applications and several research. For applications such as diseases, intelligent routing systems, and online shopping carts such as e-commerce sites, recommended systems are developed based on sentiment analysis (SA) and take accurate decision-making based on the predictions and analyze the accurate decisions based on the result analysis. When it comes to practical uses, deep learning (DL) has by far been the most popular. DL becomes an indispensable domain for several tasks in science and engineering. It is very difficult to take decisions based on traditional tests in various research areas such as disease prediction, textual sentiment analysis, and risk prediction of autonomous vehicles due to the lack of accuracy and long time for results. To address this, various approaches are proposed to adopt. Decision-making is based on multi-criticism, which is more useful to solve critical issues in making accurate decisions than previous approaches. In this paper, an improved and augmented decision-making deep learning algorithm is discussed and shows the comparison among the various DL algorithms. The performance is calculated according to the parameters.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85214004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring The in vitro Efficacy of Psidium Guajava Leaf Oil Against Cutibacterium Granulosum","authors":"Nuttakorn Baisaeng, Srikanjana Klayruang","doi":"10.59796/jcst.v13n3.2023.1032","DOIUrl":"https://doi.org/10.59796/jcst.v13n3.2023.1032","url":null,"abstract":"One potential approach to treat acne vulgaris is by utilizing Cutibacterium granulosum (C. granulosum) to break down the biofilm formed by Cutibacterium acnes (C. acnes). When using cosmeceutical products containing certain essential oils, as they may have the unintended effect of eliminating C. granulosum, leading to the potential development of more severe acne vulgaris in the long term. No data for Psidium guajava (guava) leaves oil against C. granulosum has been reported. Therefore, this study aimed to investigate in vitro antimicrobial activity of guava leaves oil against C. granulosum. This oil was extracted from the guava leaves by hydrodistillation using a clevenger-type apparatus. Then, the chemical compositions of this crude oil were identified by gas chromatography-mass spectrometry. The percentage yield of this essential oil was 0.13 ± 0.2% (w/w) on fresh weight basis. The major compounds were β-caryophyllene (25.50%), limonene (11.58%), caryophyllene oxide (3.43%),a-copaene (2.92%), 1,8-cineole (2.08%), and a-pinene (1.28%). This essential oil exerted a potent antioxidant capacity with the half maximal inhibitory concentration of 32.7 ± 0.3 mg/ml from 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Additionally, the essential oil of guava leaves showed the susceptibility of C. granulosum by agar disc diffusion method with 22 ± 0.2 mm of clear inhibition zone. This essential oil also possessed against C. granulosum with the minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) of 3.125 µg/ml and 6.25 µg/ml from the broth microdilution susceptibility test. From these findings, this essential oil exhibited notable synergistic antioxidant and antimicrobial activities against C. granulosum.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87181017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro Survival of Microencapsulated Canine-Specific Probiotics Under Simulated Gastrointestinal Tract Conditions and During Storage","authors":"Ngamlak Foongsawat, S. Sunthornthummas, A. Rangsiruji, S. Sarawaneeyaruk, Kedvadee Insian, O. Pringsulaka","doi":"10.59796/jcst.v13n3.2023.1121","DOIUrl":"https://doi.org/10.59796/jcst.v13n3.2023.1121","url":null,"abstract":"The survival of probiotics in the gastrointestinal system of dogs is crucial for them to provide health benefits. However, probiotics must also endure various physical conditions during commercial production and storage. Therefore, this study employed the microencapsulation technique to ensure the survival of probiotics using alginate as the encapsulation material, both alone and in combination with goat milk (alginate-goat milk). The study assessed the survival rates of two probiotic LAB strains, Enterococcus hirae Pom 4 and Ligilactobacillus animalis FB2, in both types of matrices under simulated dog gastrointestinal conditions, during food production, and 28 days of refrigeration at 4°C. The findings revealed that alginate-goat milk microcapsules had the highest encapsulation yield, and the viability of microencapsulated LAB cells in the alginate-goat milk matrix was the best protection for both probiotic strains under all conditions, including pasteurization temperature. Even after pasteurization, viable counts exceeding 6 log cfu/g were observed, indicating the promising application of alginate-goat milk microcapsules for optimal protection, enabling probiotics to survive until they reach the intended site and provide health benefits to dogs.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85924970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of The Application of Digital Transformation in Food Industry","authors":"Galih Nugroho, F. Tedjakusuma, D. Lo, A. Romulo, Dimas Hanung Pamungkas, Sigit Aditya Kinardi","doi":"10.59796/jcst.v13n3.2023.1285","DOIUrl":"https://doi.org/10.59796/jcst.v13n3.2023.1285","url":null,"abstract":"In recent years, food companies have been facing various challenges related to fluctuating demand and constantly evolving customer and supplier requirements. These challenges have made it necessary for food companies to adapt to new technological advancements and implement new solutions to optimize their manufacturing systems. One such solution is digital transformation, which is a suite of technologies aimed at creating smart ecosystems that can transform industrial processes. Digital transformations are designed to exploit the potential of rapidly advancing information and communication technology (ICT) in the food industry. These include digital tools such as machine learning, artificial intelligence, blockchain, and IoT or the Internet of Things. These technologies have several applications in the food industry, ranging from food supply chain management to food safety, production, and consumption.","PeriodicalId":36369,"journal":{"name":"Journal of Current Science and Technology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76069128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}