Forensic Science International: Reports最新文献

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Falls from high-altitude with no fatal injuries: Report of two autopsy cases 高空坠落未造成致命伤:两例尸检报告
Forensic Science International: Reports Pub Date : 2024-03-05 DOI: 10.1016/j.fsir.2024.100361
Tomoka Yamaguchi, Shiori Hattori, Keisuke Mizuo, Satoshi Watanabe
{"title":"Falls from high-altitude with no fatal injuries: Report of two autopsy cases","authors":"Tomoka Yamaguchi,&nbsp;Shiori Hattori,&nbsp;Keisuke Mizuo,&nbsp;Satoshi Watanabe","doi":"10.1016/j.fsir.2024.100361","DOIUrl":"10.1016/j.fsir.2024.100361","url":null,"abstract":"<div><p>We report two cases of falls from a very high altitude with no fatal injuries. Two men were found dead directly under a high bridge. Surveillance video footage indicated that they had fell approximately 120 m from the bridge to the ground. On the fall site, there was snow on the ground, and the men were completely buried in the snow. An autopsy performed at 2 days after their bodies were found, showed a small subdural hematoma in one patient and a minor pulmonary laceration in the other. However, no fatal injuries were observed. Their deaths were caused by hypothermia based directly on the difference in the coloration of the left and right cardiac blood, the bright red to reddish brown lungs, and the Wischnewski spots. The reason why no fatal injuries occurred despite falling from height was considered to be the fall onto the snow.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100361"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000100/pdfft?md5=3f703705671cad6802dd03d60db3aeb1&pid=1-s2.0-S2665910724000100-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140087316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concrete evidence: Analysis of aggregate and cement in a homicide investigation 具体证据:凶杀案调查中的骨料和水泥分析
Forensic Science International: Reports Pub Date : 2024-03-02 DOI: 10.1016/j.fsir.2024.100360
Alastair Ruffell, Jennifer M. McKinley
{"title":"Concrete evidence: Analysis of aggregate and cement in a homicide investigation","authors":"Alastair Ruffell,&nbsp;Jennifer M. McKinley","doi":"10.1016/j.fsir.2024.100360","DOIUrl":"https://doi.org/10.1016/j.fsir.2024.100360","url":null,"abstract":"<div><p>The unusual body deposition site described comprised three elements of concealment: i) a covert stream-based ravine some 60 m from the suspect’s home; ii) partial grave dug into the ravine bank and iii) final concealment using concrete slabs. Disaggregation and sieving of concrete samples from the site, suspect residence(s) and control samples was carried out. These allowed informative exclusion of all but one control sample and provided a range of possible comparisons that may reflect the sequence of concrete slab selection, transport and use in covering the victim. The textures/colours of disaggregated, dried sediment size fractions also proved useful in conveying principles of exclusion to the court and jury at a subsequent murder trial. This work flows from basic (visual) observation of dry, cut blocks, through regular laboratory procedures of thin section work to disaggregation and size separation of aggregate-cement fractions. Graphical presentation of each analysis provided effective communication of geological science during the trial at court, concluding with a verdict of guilty by aggravated murder.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100360"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000094/pdfft?md5=2a4d11d59fb4495ccb77250ad4fb6d39&pid=1-s2.0-S2665910724000094-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140051532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first X-STR population study for the South African population 首次针对南非人口的 X-STR 人口研究
Forensic Science International: Reports Pub Date : 2024-02-09 DOI: 10.1016/j.fsir.2024.100359
Amy-Leigh Whittaker, Laura Jane Heathfield
{"title":"The first X-STR population study for the South African population","authors":"Amy-Leigh Whittaker,&nbsp;Laura Jane Heathfield","doi":"10.1016/j.fsir.2024.100359","DOIUrl":"https://doi.org/10.1016/j.fsir.2024.100359","url":null,"abstract":"<div><p>The utilisation of X-chromosome short tandem repeats (X-STRs) for DNA profiling has been demonstrated to be particularly useful in resolving distant familial relations and deficiency paternity testing. The implementation of X-STRs within a medico-legal context requires baseline frequency data for the general population to allow for appropriate statistical interpretations of results. This study aimed to generate the first X-STR data for the South African population using an optimised and internally validated Qiagen Investigator Argus X-12 QS workflow. Biological samples from 1016 South African individuals (593 males and 423 females) with either African, European, Indian/Asian or mixed ancestry were processed. Herein, allele and haplotype frequencies, as well as forensic and population parameters for the four major South African population groups are reported. Locus DXS10135 was the most informative across all four population groups. Similarly, linkage group 1 had the highest haplotype diversity. An MDS plot revealed that the population groups in South Africa cluster with other global populations of similar ancestry, rather than each other. Additionally, 75 off-ladder alleles were identified, of which 37 were novel. X-STR analyses for civil inheritance disputes and the identification of unknown individuals are now possible given these data.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100359"},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000082/pdfft?md5=f2652ac72a55811eb3a53eb21888a318&pid=1-s2.0-S2665910724000082-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139749319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bloodstain pattern dynamics in microgravity: Observations of a pilot study in the next frontier of forensic science 微重力下的血迹图案动态:法医学下一个前沿领域试点研究的观察结果
Forensic Science International: Reports Pub Date : 2024-02-03 DOI: 10.1016/j.fsir.2024.100358
Zack Kowalske , George Pantalos , Abdulrahman Oleiwi , Graham Williams
{"title":"Bloodstain pattern dynamics in microgravity: Observations of a pilot study in the next frontier of forensic science","authors":"Zack Kowalske ,&nbsp;George Pantalos ,&nbsp;Abdulrahman Oleiwi ,&nbsp;Graham Williams","doi":"10.1016/j.fsir.2024.100358","DOIUrl":"https://doi.org/10.1016/j.fsir.2024.100358","url":null,"abstract":"<div><p>As humanity advances into a space-faring species, the risk of injury by multiple means and intentions will follow. Expanding understanding of how forensic science adapts to extraterrestrial environments is a novel and inevitable expansion into the next forensic frontier. This study considers the unique challenges of bloodstain pattern analysis in microgravity environments. Specifically, observation in novel experimentation aboard a parabolic flight research airplane which yielded fluid dynamic behaviors in a microgravity environment that provides practical understanding of Earth-based and off-world bloodstain applications.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100358"},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000070/pdfft?md5=ddae45d16afe2357a151986ef8ca4071&pid=1-s2.0-S2665910724000070-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Investigator® 24plex GO! kit and associated allele frequency data for four South African population groups Investigator® 24plex GO!试剂盒评估及南非四个人群的相关等位基因频率数据
Forensic Science International: Reports Pub Date : 2024-02-02 DOI: 10.1016/j.fsir.2024.100357
Laura Jane Heathfield , Lorraine Nel, Kate Megan Reid
{"title":"Evaluation of the Investigator® 24plex GO! kit and associated allele frequency data for four South African population groups","authors":"Laura Jane Heathfield ,&nbsp;Lorraine Nel,&nbsp;Kate Megan Reid","doi":"10.1016/j.fsir.2024.100357","DOIUrl":"10.1016/j.fsir.2024.100357","url":null,"abstract":"<div><p>In this study, population data were generated from South Africans using the Investigator® 24plex GO! Kit (QIAGEN, Hilden, Germany). Participants represented the four major population groups in South Africa, with self-reported ancestral origin being African (n = 208), European (n = 213), Indian/Asian (n = 103) or Admixed (n = 209). Allele frequency data and forensic parameters were calculated for each population group using Arlequin (v.3.5.2.2) and FORSTAT (v1.0). TPOX had the lowest discrimination capacity for all population groups, except for the African population group where THO1 was the least informative. SE33 had the highest discrimination capacity for all population groups (&gt;0.98), with 38 different alleles observed in the Admixed population group. Samples exhibiting novel alleles or anomalies underwent massively parallel sequencing using the ForenSeq™ DNA Signature Prep kit, which confirmed the following results: one null Y allele at Amelogenin, ten instances of TPOX tri-allelism and four novel micro-variant alleles. An additional four novel alleles in SE33 were observed but remain unconfirmed, due to SE33 not being included in the ForenSeq™ DNA Signature Prep kit. Moreover, nine individuals had an allele 8 or 9 at D1S1656, where the peaks for these alleles occur before the D1S1656 marker range on the electropherogram and showed as a peak within the DYS391 marker. Although this observation was rare overall (1.2%), these nine individuals were from three of the four population groups, which motivates for the adjustment of the Investigator® 24plex PCR chemistry to avoid allelic overlap of D1S1656 with DYS391. Overall, these findings highlight the diverse genetic makeup of the South Africa population and accentuate the importance of local population studies.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100357"},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000069/pdfft?md5=bdf94b977f82ace65cfd4c265bc4f295&pid=1-s2.0-S2665910724000069-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139687053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Domestic violence in Kazakhstan: Forensic-medical and medical-social aspects 哈萨克斯坦的家庭暴力问题:法医-医疗和医疗-社会问题
Forensic Science International: Reports Pub Date : 2024-01-28 DOI: 10.1016/j.fsir.2024.100356
Saule A. Mussabekova , Xeniya E. Mkhitaryan , Khamida R. Abdikadirova
{"title":"Domestic violence in Kazakhstan: Forensic-medical and medical-social aspects","authors":"Saule A. Mussabekova ,&nbsp;Xeniya E. Mkhitaryan ,&nbsp;Khamida R. Abdikadirova","doi":"10.1016/j.fsir.2024.100356","DOIUrl":"10.1016/j.fsir.2024.100356","url":null,"abstract":"<div><h3>Background</h3><p>The consequences of domestic violence can be very serious for both individuals and society as a whole. Domestic violence, being one of the widespread instruments of dependence, requires study by forensic-investigative, forensic-medical and public organizations. The prospectivity of studying the forensic-medical aspects of this problem by analyzing the conditions, patterns of distribution of various forms of violence subsequently develops into a more objective approach to solving questions about the mechanisms and features of the formation of injuries, depending on the indicated situations.</p></div><div><h3>Aim</h3><p>to assess the national prevalence of domestic violence against women in Kazakhstan, to identify demographic, socio-economic and medical-social predictors that determine the prevalence of violence against women in modern conditions.</p></div><div><h3>Methods</h3><p>A qualitative-quantitative study was conducted in 14 regions of the Republic of Kazakhstan in the period from 2019 to 2022. The analysis was carried out based on the results of forensic medical reports and the results of a survey of 14,342 women who applied to the regional branches of the Center for Forensic Examinations of the Ministry of Justice of the Republic of Kazakhstan. The study used an adapted version of the questionnaire of the United Nations Economic Commission for Europe about violence against women based on the methodology of the WHO Cross-Country Study on women's health and domestic violence against women. Applied statistical analysis methods were used to analyze the obtained results.</p></div><div><h3>Results</h3><p>There has been an increase in cases of domestic violence over the past two years, especially in 2022. The main victims of domestic violence in the territory of the Republic of Kazakhstan are women (more than 77.9%), children - 17.52%, elderly people - 3.5% and men - less than 1.1%. The number of cases of domestic violence against women in different regions of the Republic of Kazakhstan differs significantly (p &lt; 0.05) and is more apparent in large cities. The most vulnerable category are women aged 40 to 49 (41.46%) and 30 to 39 (37.80%). Women in the Republic of Kazakhstan</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100356"},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000057/pdfft?md5=b2db46ec60f8e4a60c302ed83fa78698&pid=1-s2.0-S2665910724000057-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139632669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging methods of human microbiome analysis and its forensic applications: Review 新出现的人类微生物组分析方法及其法医应用:评论
Forensic Science International: Reports Pub Date : 2024-01-22 DOI: 10.1016/j.fsir.2024.100355
Amy Arabella Singh, Moses Okpeku
{"title":"Emerging methods of human microbiome analysis and its forensic applications: Review","authors":"Amy Arabella Singh,&nbsp;Moses Okpeku","doi":"10.1016/j.fsir.2024.100355","DOIUrl":"10.1016/j.fsir.2024.100355","url":null,"abstract":"<div><p>The human microbiome comprises trillions of microbial cells, primarily bacteria, found in places such as the gut, oral cavity, and skin. The human microbiome holds significant potential in forensic investigations, with important applications in post-mortem analysis, geographical identifications, sexual assault cases, and personal identification. The human microbiome displays significant variations, which can be utilized to distinguish individuals based on their distinctive microbial signatures, thus facilitating identification. Microbiome composition varies geographically and can be explored for identification of individuals’ origin or location. In addition, changes observed in microbial composition during different stages of decomposition can provide valuable insight into the time and location of death which can assist in forensic investigations. However, the use of microbiomes in forensic investigation is still developing and under-utilized, especially in the developing world. This article reviewed emerging microbiome analyses, their strengths, limitations, and potential for future research in forensic investigations. In particular five microbiomic forensic applications were looked at; postmortem analysis, geographical identification, sexual assault cases, bite marks and personal identification. Despite challenges and limitations associated with storage sensitivity, limited samples, and lack of standardization, the use of microbiomes in forensic investigation is quite promising. However, future research should focus on more extensive and standardized studies to overcome these challenges and fully harness the potential of the human microbiome in forensic investigations, enabling its practical application in various forensic scenarios.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100355"},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000045/pdfft?md5=3def5ce66ae8fc6008a8cd50ad2676ea&pid=1-s2.0-S2665910724000045-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139632416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anthropometric examination of footprints in South Indian population for sex estimation 对南印度人口脚印进行人体测量学检查以估测性别
Forensic Science International: Reports Pub Date : 2024-01-17 DOI: 10.1016/j.fsir.2024.100354
Sravya Palla , Anitha Shivajirao
{"title":"Anthropometric examination of footprints in South Indian population for sex estimation","authors":"Sravya Palla ,&nbsp;Anitha Shivajirao","doi":"10.1016/j.fsir.2024.100354","DOIUrl":"10.1016/j.fsir.2024.100354","url":null,"abstract":"<div><h3>Background</h3><p>Individualisation is essential when assessing physical evidence that is discovered at a crime scene to connect the evidence to a suspect or victim. Many studies on the identification of an individual from various evidence types have been conducted across the globe. Once identified, a person's sex completes 50% of the individualisation process, which assists the investigator in leading the investigation in a specific direction by narrowing down the pool of suspects. The current study intends to ascertain an individual's sex, be it male or female, based on footprint evidence, which is a highly neglected research area. The present study is part of an anthropometrical research in which seven different footprint measurements, specifically lengths and widths, were recorded and statistically assessed to determine a person's sex from inked bilateral footprints of 132 individuals (61 males and 71 females) aged 18–50 years, who were born in South India.</p></div><div><h3>Results</h3><p>The t-test scores show that the right footprint parameters are similar to the left footprint, except T1 (Length between the pternion and the first toe anterior point) and B1 (Total Ball Breadth) in females. T4_R (Length between the pternion and the fourth toe anterior end of the right foot) exhibited the strongest correlation with sex. In contrast, HB_Index_R (Heel ball index of right foot) exhibited the weakest correlation. The male and female footprints achieved 77% and 93% accuracy rates, respectively.</p></div><div><h3>Conclusions</h3><p>A person's sex can be established, to a satisfactory degree, with the help of individual footprint measurements. Further studies can develop population-specific footprint standards to help investigators hasten the identification process.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100354"},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000033/pdfft?md5=dfd24614a582a87c501e3ca52fab7e63&pid=1-s2.0-S2665910724000033-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139537590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the accuracy of the program Stature for stature estimation in White South Africans 评估 "身材 "程序在估计南非白人身材方面的准确性
Forensic Science International: Reports Pub Date : 2024-01-15 DOI: 10.1016/j.fsir.2024.100353
Natasha R. Loubser , Amy J. Spies , Desiré Brits
{"title":"Assessing the accuracy of the program Stature for stature estimation in White South Africans","authors":"Natasha R. Loubser ,&nbsp;Amy J. Spies ,&nbsp;Desiré Brits","doi":"10.1016/j.fsir.2024.100353","DOIUrl":"10.1016/j.fsir.2024.100353","url":null,"abstract":"<div><p>In 2016, Polcerová and Králik created an open-access software program, <em>Stature</em>, designed to automate the estimation of living stature in forensic and archaeological cases. This program includes 22 equations from 13 publications, based on both anatomical and mathematical methods to automate stature estimations. This program does not currently include any population data relating to South Africa, and therefore, this study aimed to assess the accuracy of the program <em>Stature</em> to estimate living stature from the skeletal remains of White South African adults. The living stature of 40 male and 20 female White South African adults from the Raymond A. Dart Collection of Modern Human Skeletons was automatically estimated by the program (ELS<sub>P</sub>). These estimates were then compared to stature estimates generated by the multivariate equation using the physiological length of the femur and tibial length formulated specifically for the estimation of stature of White South Africans (ELS<sub>D</sub>). The vast majority of the ELS<sub>P</sub> significantly under- or overestimated the living stature of this sample, however various ELS<sub>P</sub> did estimate stature with a sufficient degree of accuracy. It was found that the estimates which were significantly different were associated with the largest inaccuracies, biases, and SEE values and are not applicable to this population group. The equations, using standardised measurements, which were not significantly different could accurately estimate the living stature of White South Africans, however, it is recommended that the data of White South African populations be incorporated into the program <em>Stature</em> for increased accuracy and diversity.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100353"},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000021/pdfft?md5=dc3461c6617b8ab301888ced219bc935&pid=1-s2.0-S2665910724000021-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139539925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dangers of Chemsex: an autopsy case report 化学性行为的危险:尸检病例报告
Forensic Science International: Reports Pub Date : 2024-01-10 DOI: 10.1016/j.fsir.2024.100352
A. Levasseur , C. Houssaye , A. Knapp-Gisclon , C. Mayer-Duverneuil , I. Etting , G. Lorin de la Grandmaison , J.-C. Alvarez
{"title":"Dangers of Chemsex: an autopsy case report","authors":"A. Levasseur ,&nbsp;C. Houssaye ,&nbsp;A. Knapp-Gisclon ,&nbsp;C. Mayer-Duverneuil ,&nbsp;I. Etting ,&nbsp;G. Lorin de la Grandmaison ,&nbsp;J.-C. Alvarez","doi":"10.1016/j.fsir.2024.100352","DOIUrl":"10.1016/j.fsir.2024.100352","url":null,"abstract":"<div><h3>Background</h3><p>\"<em>Chemsex</em>\" is an emerging practice all over the world, sometimes fatal for its users. The victim, a 36-year-old martial arts athlete, was found lifeless lying on his back on the ground in the woods, with a rope tied around the neck, passing over the branch of a tree 2 m from the ground, the other end of the ligature being held in the dead body’s right hand. A third party (a male prostitute) was present at the time of death.</p></div><div><h3>Material and methods</h3><p>A forensic autopsy was performed 48 h after death, including a complete histologic examination of most organs and toxicological analyses. Blood, hair, and organs were analysed for drugs and narcotics (LC-MS/MS and GC-MS), and alcohol was determined by GC-FID.</p></div><div><h3>Results and discussion</h3><p>Autopsy findings showed moderate asphyxia syndrome without clear skin ligature marks, but there were deep cervical contusions. Other contusions were found including deep bruises in the dorsal area and superficial hemorrhagic infiltration of the medial surface of both wrists. Focal bruising of the tongue was found. Organs showed no significant pathology. There was a residual thymus, suggesting chronic drug addiction. Histological examination showed frank signs of hemodynamic shock. Foci of contusions found during autopsy were confirmed, showing no inflammatory reaction. Foci of granular cylinders were present in renal tubules. Heart showed focal non-specific endocardial fibrosis. Toxicological findings were the following ones: (1) peripheral blood: THC at 0.1 ng/mL, THC-COOH at 1 ng/mL, with no 11-OH-THC, indicating last use more than 12 h before death; 3-MMC, NPS-type cathinone at 960 ng/mL, a high, potentially lethal concentration; GHB (gamma-hydroxybutyric acid) at 24 mg/L, a medium concentration, but consistent with last use in the hours before death; ethanol at 0.73 g/L, a relatively low concentration, but which potentiates the toxic effects of the associated molecules. (2) Hair: 3-MMC at 1986 pg/mg, consistent with chronic use in the last few months. (3) Viscera: 3-MMC at 700 ng/mg in the brain, suggesting a cerebral distribution of this molecule. The cardio-femoral ratio of 7.6 was consistent with <em>post mortem</em> release from the heart and/or diffusion from the stomach and/or reservoir organs.</p></div><div><h3>Conclusion</h3><p>We present a case of lethal mechanical asphyxia by atypical hanging, which occurred after recent consumption of 3-MMC and GHB, which contributed to the death in a context of chemsex, which is sometimes associated with sadomasochistic practices such as strangulation. As there was a third-party present at the time of death, according to the police investigation, manner of death was undetermined, as homicide possibly by strangulation was not formally ruled out. This autopsy case illustrates the need to carefully confront police investigations with complete forensic investigations, including exhaustive toxicologic","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"9 ","pages":"Article 100352"},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266591072400001X/pdfft?md5=f46b0d7701ae128ebbf6996795b492c6&pid=1-s2.0-S266591072400001X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139456398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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