Forensic Science International: Reports最新文献

筛选
英文 中文
From death to the Virgin birth: Multi-analytical investigation of a suspected 16th century painting 从死亡到圣母诞生对一幅疑似 16 世纪绘画的多重分析调查
Forensic Science International: Reports Pub Date : 2024-11-07 DOI: 10.1016/j.fsir.2024.100392
Michelle G. Carlin , Nicola Grimaldi
{"title":"From death to the Virgin birth: Multi-analytical investigation of a suspected 16th century painting","authors":"Michelle G. Carlin ,&nbsp;Nicola Grimaldi","doi":"10.1016/j.fsir.2024.100392","DOIUrl":"10.1016/j.fsir.2024.100392","url":null,"abstract":"<div><div>A painting depicting St John the Baptist prior to his brutal execution, until recently, was held in storage at the Bowes Museum in the North of England, UK. Owing to weakened joins in the wood panel the painting was marked for art conservation treatments, examination and analysis. However, other than the fact that the records show it purchased in Italy in the late nineteenth century by museum founders John and Joséphine Bowes, little else is known of the work. Through a combination of chemical testing and technical art history, further knowledge of the painting has been established. Preparation of cross sections of paint was carried out, as well as chemical testing involving pyrolysis gas chromatography – mass spectrometry (py-GCMS) and attenuated total reflectance – Fourier transform infrared spectroscopy (ATR-FTIR), lead white, chalk and linseed oil as binder were identified. The presence of an aged natural resin on the surface of the painting, presence of a thick gesso ground layer, as well as examination of the wood panel construction provided insight into the techniques used in the artwork and that they are comparable with late Medieval to early Renaissance period methods. During examination of the cross-section images, it was noted that there was a second preparatory ground layer in the central part of the sequence; this feature prompted further multi-spectral photography and analysis. X-radiography a commonly used technique for painting analysis surprisingly revealed an entirely different image depicting a nativity scene which had been previously completely concealed by the painting of St John we see today. Although an unexpected discovery still presents some unanswered questions such as who the original artist was and why was the panel so radically reworked. This investigation began with the depiction of the imminent death of the St John the Baptist and ended with the virgin birth. This analytical methodology was applied in technical art history but may also have applications in forensic investigations of suspected fraudulent works of art.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100392"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medico-legal analysis of the correlation between head trauma and aneurysm rupture: A case report 头部外伤与动脉瘤破裂之间相关性的医学法律分析:病例报告
Forensic Science International: Reports Pub Date : 2024-10-18 DOI: 10.1016/j.fsir.2024.100390
Emanuele Capasso, Gaetano Di Donna, Roberto Cortese, Verdiana De Caro, Fabio Policino
{"title":"Medico-legal analysis of the correlation between head trauma and aneurysm rupture: A case report","authors":"Emanuele Capasso,&nbsp;Gaetano Di Donna,&nbsp;Roberto Cortese,&nbsp;Verdiana De Caro,&nbsp;Fabio Policino","doi":"10.1016/j.fsir.2024.100390","DOIUrl":"10.1016/j.fsir.2024.100390","url":null,"abstract":"<div><div>We present the case of a 54 years old man who was found in a state of confusion and a forehead wound. Transported to the closest E.R., a brain CT scan showed massive subarachnoid hemorrhage and an angiographic exam showed a ruptured aneurysm of the cavernous siphon. Death occurred 4 days after admission. The autopsy showed the presence of a linear wound on the forehead which was considered a sharp force injury. The aneurysm rupture was therefore considered as a consequence of the head trauma associated to the frontal wound. In the medico-legal analysis of the case primary importance was given to the distinction between potential homicide, suicide or accident. In the end, based on the morphological features of the forehead wound, this case was defined as of potentially homicidal nature, so that the responsible of stab wound should be considered accountable for the man’s death.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100390"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142532121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management and disposal of human remains acquired for medical education – A forensic perspective 管理和处置为医学教育获取的遗骸--法医学视角
Forensic Science International: Reports Pub Date : 2024-10-11 DOI: 10.1016/j.fsir.2024.100389
Neelkamal Battu , Rutuja Kanekar , Siddharth Sawardekar , Girish Tasgaonkar, Vikrant Waghmare
{"title":"Management and disposal of human remains acquired for medical education – A forensic perspective","authors":"Neelkamal Battu ,&nbsp;Rutuja Kanekar ,&nbsp;Siddharth Sawardekar ,&nbsp;Girish Tasgaonkar,&nbsp;Vikrant Waghmare","doi":"10.1016/j.fsir.2024.100389","DOIUrl":"10.1016/j.fsir.2024.100389","url":null,"abstract":"<div><div>In medical schools, the foundational subject of human anatomy usually requires the medical students to procure a set of human bones, either real or artificial, for comprehensive understanding of the human body. The proper maintenance and disposal of these human remains is the responsibility of the students and the institutions possessing the remains. Improper disposal of human remains can have far-reaching implications, including ethical, legal, public health, environmental, social, and psychological consequences. We present a case of a human skull used for medical studies found dumped in a garbage, leading to unnecessary investigation by the law authorities. The case brings to light the need for including ethical disposal of academic human skeletons at the beginning of the medical curriculum. The authors also discuss in detail the various legal provisions and cultural practices of disposal of human remains in the Indian scenario.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100389"},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142532120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amino acid sensitive latent fingermark detection formulations based upon improvised carrier solvents for resource-limited environments: A proof-of-concept study 基于简易载体溶剂的氨基酸敏感潜伏指痕检测配方,适用于资源有限的环境:概念验证研究
Forensic Science International: Reports Pub Date : 2024-09-19 DOI: 10.1016/j.fsir.2024.100388
Emma C. Jones , Jordan F.L. Hooper , Jemmy T. Bouzin , Renee Wilson , Simon W. Lewis
{"title":"Amino acid sensitive latent fingermark detection formulations based upon improvised carrier solvents for resource-limited environments: A proof-of-concept study","authors":"Emma C. Jones ,&nbsp;Jordan F.L. Hooper ,&nbsp;Jemmy T. Bouzin ,&nbsp;Renee Wilson ,&nbsp;Simon W. Lewis","doi":"10.1016/j.fsir.2024.100388","DOIUrl":"10.1016/j.fsir.2024.100388","url":null,"abstract":"<div><div>HFE-7100 and petroleum ether (bp 40–60 °C) are routine carrier solvents used in amino acid sensitive fingermark reagents such as 1,2-indanedione/zinc chloride (IND-Zn) and ninhydrin. However, limited resource jurisdictions face major challenges in sourcing laboratory-grade reagents due to budgetary and geographical restrictions. Common hydrocarbon solvents, available from hardware stores and similar outlets, may offer a more readily available and inexpensive alternative for such jurisdictions. This study assessed the range of improvised carrier solvents for their suitability in the IND-Zn formulation and found that eight different hydrocarbon solvents were able to develop fingermarks when substituted into the formulation. The formulation based on shellite solvent outperformed all other improvised formulations tested, providing high-quality fingermarks and similar sensitivity to a petroleum ether (bp 40–60 °C) based formulation across six porous substrates using six donors. A similar approach was applied to ninhydrin, where it was discovered that formulations using kerosene, white spirits and shellite as carrier solvents performed comparably to a formulation based on petroleum ether (bp 40–60 °C). By chemically characterising each solvent using gas chromatography-mass spectrometry, this study also provided a greater understanding of how the chemical composition of a carrier solvent impacts the efficacy of the resulting IND-Zn formulation, emphasising that hydrocarbon solvents should contain short-chain alkanes and minimal aromatic content to give a more volatile formulation. Additionally, the identity of the solvent was found to cause slight differences in the colour and luminescence intensity of ink diffusion on porous substrates. These results indicate that improvised hydrocarbon solvents are suitable alternatives to common carrier solvents with their operational use offering major benefits for limited resource jurisdictions by reducing costs and supply chain risks. A thorough risk assessment must be conducted by each jurisdiction that intends to use this method as health and safety considerations are concerns with these improvised solvents.</div></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100388"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142323033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A preliminary evaluation of the effects of aquatic environments on the recovery of fingermarks on porous substrates 水生环境对多孔底质上指痕复原影响的初步评估
Forensic Science International: Reports Pub Date : 2024-09-10 DOI: 10.1016/j.fsir.2024.100387
Amanda A. Frick , Ian Yi Liang Lim , Paola A. Magni
{"title":"A preliminary evaluation of the effects of aquatic environments on the recovery of fingermarks on porous substrates","authors":"Amanda A. Frick ,&nbsp;Ian Yi Liang Lim ,&nbsp;Paola A. Magni","doi":"10.1016/j.fsir.2024.100387","DOIUrl":"10.1016/j.fsir.2024.100387","url":null,"abstract":"<div><p>Latent fingermark detection can become increasingly difficult in the weeks following deposition, due to chemical and physical changes influenced by environment. There has been increased research interest into ageing mechanisms of fingermark residue, however these studies have typically been conducted in dry, indoors conditions. Less information is available regarding degradation processes that may occur in scenarios involving water and the potential longevity of porous substrates under such conditions. A pilot study was conducted to investigate the performances of Oil Red O (ORO) and physical developer (PD) on samples submerged in different aquatic environments in a laboratory setting. Charged fingermarks from three donors were deposited on copy paper and immersed in either salt water or freshwater; still or with water flow. Samples were treated at multiple intervals (1, 12, 20 and 40 days) after submersion. Results showed that high quality of development could be achieved up to 40 days after immersion. The overall performances of ORO and PD were generally unaffected in the early stages of the study. Physical and chemical degradation of both latent residue and substrate were observed, which were increased by salt and water movement. While PD appeared to be less affected by potential chemical changes, it was less effective than ORO due to substrate degradation in moving salt water. These results present the first steps towards better understanding the practical effects of degradation processes specific to fingermarks on porous substrates underwater.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100387"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000367/pdfft?md5=8dd39d955eb7e5b7874585aa0f6ed265&pid=1-s2.0-S2665910724000367-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex estimation from the first and second ribs using 3D postmortem CT images in a Japanese population: A comparison of discriminant analysis and machine learning techniques 在日本人群中使用三维尸检 CT 图像从第一和第二肋骨估测性别:判别分析与机器学习技术的比较
Forensic Science International: Reports Pub Date : 2024-08-31 DOI: 10.1016/j.fsir.2024.100386
Tawachai Monum , Yohsuke Makino , Daisuke Yajima , Go Inoguchi , Fumiko Chiba , Suguru Torimitsu , Maiko Yoshida , Patison Palee , Yumi Hoshioka , Naoki Saito , Hirotaro Iwase
{"title":"Sex estimation from the first and second ribs using 3D postmortem CT images in a Japanese population: A comparison of discriminant analysis and machine learning techniques","authors":"Tawachai Monum ,&nbsp;Yohsuke Makino ,&nbsp;Daisuke Yajima ,&nbsp;Go Inoguchi ,&nbsp;Fumiko Chiba ,&nbsp;Suguru Torimitsu ,&nbsp;Maiko Yoshida ,&nbsp;Patison Palee ,&nbsp;Yumi Hoshioka ,&nbsp;Naoki Saito ,&nbsp;Hirotaro Iwase","doi":"10.1016/j.fsir.2024.100386","DOIUrl":"10.1016/j.fsir.2024.100386","url":null,"abstract":"<div><p>This study investigated the use of 3D postmortem computed tomography (PMCT) images of the first and second ribs for sex estimation in a Japanese population. Sex estimation models using conventional discriminant analysis and ten machine learning algorithms including logistic regression (LR), Naive Bayes (NB), K-Nearest Neighbors (KNN), decision tree (DT), random forest (RF), support vector machine (SVM), linear discriminant analysis (LDA), quadratic discriminant analysis (QDA), artificial neural network (ANN), and extra tree (ET), were achieved from PMCT measurements of the first and second rib and the accuracy of models were compared. The results showed that ML algorithms, particularly LR, outperformed discriminant analysis, achieving an accuracy of 83.6 % compared to 79.1 % for stepwise discriminant analysis. This study highlights the potential of 3D PMCT and ML for accurate sex estimation in forensic anthropology.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100386"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000355/pdfft?md5=da64721ec3c54df285b9cb30377348ad&pid=1-s2.0-S2665910724000355-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rectal foreign body with giant bladder stone; An autopsy case of unusual autoerotic death 直肠异物伴巨大膀胱结石;一例不寻常的自体死亡尸检病例
Forensic Science International: Reports Pub Date : 2024-08-29 DOI: 10.1016/j.fsir.2024.100385
Tadashi Hosoya , Kazuki Harada , Jun Kanetake
{"title":"A rectal foreign body with giant bladder stone; An autopsy case of unusual autoerotic death","authors":"Tadashi Hosoya ,&nbsp;Kazuki Harada ,&nbsp;Jun Kanetake","doi":"10.1016/j.fsir.2024.100385","DOIUrl":"10.1016/j.fsir.2024.100385","url":null,"abstract":"<div><p>A man in his 60 s, who had experienced sustained abdominal pain intermittently for three years, lost consciousness and was transferred to an emergency hospital, where he was pronounced dead. In the forensic autopsy, a giant bladder stone measuring 6.5 × 6.0 × 4.0 cm was found adhering to an aluminum eyeliner that penetrated the anterior wall of his rectum. This might have induced pyelonephritis in the left kidney, resulting in sepsis. The deceased may have inserted the eyeliner for sexual stimulation. However, the eyeliner did not injure the peritoneum and no peritonitis occurred, which probably prevented acute sepsis immediately after insertion. The exact time of penetration was undetermined; however, the rectal foreign body may have been retained for three years. This case suggests that sexual activity should be considered a possible manner of death, even if it took place several years previously.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100385"},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000343/pdfft?md5=8f4eaf96e1449725b6ad4e9cd3ec889e&pid=1-s2.0-S2665910724000343-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving DNA recovery and sample throughput using the PrepFiler™ Automated Forensic DNA Extraction Kit on two customised Tecan Fluent® 1080 Automated Workstations 在两台定制的 Tecan Fluent® 1080 自动化工作站上使用 PrepFiler™ 自动化法医 DNA 提取试剂盒,提高 DNA 回收率和样本处理量
Forensic Science International: Reports Pub Date : 2024-08-09 DOI: 10.1016/j.fsir.2024.100384
Nicholas J. O’Rourke, Nicholas S. Steele, Jasmine W. Tay, Colby M. Hymus, Nicholas S. Mountford, Tania M. Neave, Marie S. Rye
{"title":"Improving DNA recovery and sample throughput using the PrepFiler™ Automated Forensic DNA Extraction Kit on two customised Tecan Fluent® 1080 Automated Workstations","authors":"Nicholas J. O’Rourke,&nbsp;Nicholas S. Steele,&nbsp;Jasmine W. Tay,&nbsp;Colby M. Hymus,&nbsp;Nicholas S. Mountford,&nbsp;Tania M. Neave,&nbsp;Marie S. Rye","doi":"10.1016/j.fsir.2024.100384","DOIUrl":"10.1016/j.fsir.2024.100384","url":null,"abstract":"<div><p>One of the primary goals of forensic laboratories performing DNA recovery and profiling is obtaining a high-quality DNA extract from crime scene samples. This is largely dependent on the sensitivity and reliability of the DNA extraction chemistry utilised, as well as the liquid handling and contamination minimisation techniques employed. Automation of DNA extraction methods on large liquid handling platforms allows high-throughput laboratories to apply sensitive chemistries to reliably process a large number of samples, while minimising manual processes and cross-contamination.</p><p>This study describes the first known implementation of the PrepFiler™ Automated Forensic DNA Extraction Kit on a Tecan Fluent® Gx 1080 Automation Workstation. Two Workstations were customised with the addition of novel “Safe Pipetting Modules” to eliminate sample crossover between wells, which is important in a forensic biology setting to reduce inadvertent DNA transfer. A comparison of DNA extraction efficiency between an optimised PrepFiler™ method and the DNA IQ™ System performed on a Perkin Elmer Janus® Integrator platform showed the optimised PrepFiler™ method consistently extracted a higher yield of DNA from a range of blood inputs, as well as blood and buccal swabs. The PrepFiler™ chemistry also more efficiently removed humic acid and haematin, reducing subsequent PCR inhibition. The subsequent implementation of the optimised PrepFiler™ method onto the Tecan Fluent® Gx workstations showed a further increase in sensitivity, with no evidence of DNA cross-contamination observed. However, the optimised PrepFiler™ method encountered difficulties extracting DNA from fabric substrates, with the PrepFiler <em>Express</em>™ chemistry extracting higher yields on the cartridge-based AutoMate <em>Express</em>™ System.</p><p>Overall, this study demonstrated the Tecan Fluent® Gx 1080 Automation Workstation is a sensitive, reliable and robust method for DNA extraction using the PrepFiler™ Automated Forensic DNA Extraction Kit, and the addition of the novel Safe Pipetting Module makes this platform an attractive option for forensic biology laboratories where minimising inadvertent DNA transfer is of paramount importance.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100384"},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000331/pdfft?md5=46110917741b3c773b417e3b9393aed2&pid=1-s2.0-S2665910724000331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141964051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of indirect heroin biomarkers in biological samples of heroin users 测定海洛因使用者生物样本中的间接海洛因生物标志物
Forensic Science International: Reports Pub Date : 2024-07-29 DOI: 10.1016/j.fsir.2024.100383
Chrysoula Karakasi , Panagiota Nikolaou , Georgia Petropoulou , Sotirios Athanaselis , Emmanouil Sakelliadis , Artemisia Dona , Ioannis Papoutsis
{"title":"Determination of indirect heroin biomarkers in biological samples of heroin users","authors":"Chrysoula Karakasi ,&nbsp;Panagiota Nikolaou ,&nbsp;Georgia Petropoulou ,&nbsp;Sotirios Athanaselis ,&nbsp;Emmanouil Sakelliadis ,&nbsp;Artemisia Dona ,&nbsp;Ioannis Papoutsis","doi":"10.1016/j.fsir.2024.100383","DOIUrl":"10.1016/j.fsir.2024.100383","url":null,"abstract":"<div><p>Heroin use is responsible for many drug-related deaths, so the determination of its biomarkers, except for 6-acetylmorphine, in biological samples, is of particular concern in toxicological laboratories worldwide, for a better investigation of these cases. Th use of 6-acetylmorphine as a heroin biomarker has some limitations due to its rapid bioconversion to morphine within a few hours, especially in blood samples. The need for new indirect biomarkers, like the ones that come from the processing of opium during the clandestine production of heroin, becomes imperative. A GC/MS method was developed and validated for the determination of meconin, thebaine, papaverine, acetylcodeine and noscapine, along with morphine, codeine and 6-acetylmorphine, in different biological samples of heroin users. For all analytes and all individual biological samples, the LOD and LOQ were 2.00 and 5.00 ng/mL, respectively, the calibration curves were linear (R<sup>2</sup>≥0.991) from 5.00 to 500.0 ng/mL, and absolute recoveries were higher than 91.9 %. The method was applied during the toxicological investigation of 34 forensic cases after positive immunoassay screening for opiates. The results indicate that meconin is the most frequently detected indirect biomarker of heroin use, as it was found in 91.2 % of all cases, whilst in 23.5 % of them no 6-acetylmorphine was detected. Papaverine was found in 67.6 % of all cases and is considered to be the second most important indirect biomarker of heroin use. The establishment of detecting meconin and papaverine in biological materials in parallel with the detection of morphine, codeine and 6-acetylmorphine can contribute to more conclusive results concerning heroin use in forensic cases.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100383"},"PeriodicalIF":0.0,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266591072400032X/pdfft?md5=0770bf5cb029709b3436a4965bf61ca4&pid=1-s2.0-S266591072400032X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141961444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discriminant function for grouping subjects into legal age of 12 and 14 years using maturity indices of seven mandibular teeth on panoramic radiograph – A cross sectional study 利用全景 X 光片上七颗下颌牙齿的成熟度指数将受试者分为 12 岁和 14 岁法定年龄组的判别功能 - 一项横断面研究
Forensic Science International: Reports Pub Date : 2024-07-23 DOI: 10.1016/j.fsir.2024.100381
Rachana Prabhu , Laxmikanth Chatra , Yashaswini
{"title":"Discriminant function for grouping subjects into legal age of 12 and 14 years using maturity indices of seven mandibular teeth on panoramic radiograph – A cross sectional study","authors":"Rachana Prabhu ,&nbsp;Laxmikanth Chatra ,&nbsp;Yashaswini","doi":"10.1016/j.fsir.2024.100381","DOIUrl":"10.1016/j.fsir.2024.100381","url":null,"abstract":"<div><p>In forensic science, accurate age estimation becomes crucial, especially in cases where information about the deceased is unavailable. The legal categorization of children into age groups, notably at 12 and 14 years, holds significant importance in various legal and social contexts. Despite the importance of such categorizations, the existing literature lacks ample studies addressing the specific classification of children into these legal age groups. This study aims to identify the key variables that distinguish between the categories of 12 and 14 years of age. Additionally, it seeks to calculate and compare the sensitivity, specificity, and overall accuracy of the discriminant function in accurately determining the required age. The oral panoramic radiographs (OPGs) of 3058 children aged between 5 and 16 years from six South Indian states were evaluated. The dataset was divided into train and test data sets. Dental maturity for each individual was estimated by considering the number of fully developed permanent mandibular teeth on the left side and the normalized measurement of the open apices of all seven teeth. Linear discriminant functions for the age groups of 12 and 14 years were computed using the training data. The discriminant functions for the 12-year age group demonstrated an accuracy of, 78.0 %, while those for the 14-year age group achieved an accuracy of .71.2 %. The sensitivity and specificity of the discriminant functions for the 12-year age group were 74.5 % and, 84.6 %, respectively. In the case of the 14-year age group, the sensitivity and specificity were 72.5 % and 70.0 %, respectively. This study concludes that the discriminant functions utilized herein exhibited commendable performance in accurately classifying individuals within the specified age groups of 12 and 14 years.</p></div>","PeriodicalId":36331,"journal":{"name":"Forensic Science International: Reports","volume":"10 ","pages":"Article 100381"},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2665910724000306/pdfft?md5=7be8846e58f6947e036dc8cc9ceda21e&pid=1-s2.0-S2665910724000306-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141950546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信