Acta Marisiensis - Seria Medica最新文献_第8页

Prosthetic management of acquired dentate maxillectomy defects: A clinical case series 获得性齿状上颌切除缺损的修复治疗:临床病例系列

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0009

Vineet Sharma, Jyoti Paliwal, B. Gurjar, K. Meena

{"title":"Prosthetic management of acquired dentate maxillectomy defects: A clinical case series","authors":"Vineet Sharma, Jyoti Paliwal, B. Gurjar, K. Meena","doi":"10.2478/amma-2022-0009","DOIUrl":"https://doi.org/10.2478/amma-2022-0009","url":null,"abstract":"Abstract Acquired maxillectomy defects produce hypernasal speech, food, and liquid regurgitation into the nasal cavity, impaired deglutition and mastication, and cosmetic deformity. Furthermore, patients with acquired maxillary defects face psychosocial stigma, which has a negative impact on their quality of life. Prosthetic rehabilitation of such defects is required for stomatognathic system restoration and oroantral communication obturation. This case series discusses the fabrication of surgical, interim, and definitive obturator prostheses to restore the acquired dentate maxillectomy defects of three cancer patients. All patients had their treatment in the prosthodontics department of the RUHS College of Dental Sciences. The surgical obturator prosthesis was made before surgery, whereas the interim and definitive obturators were made one month and six months after surgery, respectively. The surgical obturator formed a shield between the surgical pack and the oral cavity. After the surgical obturator and packing were removed, an interim obturator was inserted for three to six months to allow the surgical site to heal. After the surgical site had healed, the fabrication of the definitive obturator began. Prosthetic rehabilitation with obturator prostheses sealed the acquired tissue defects of the palate and restored swallowing, speaking, chewing capacity, and cosmetic value, as well as significantly improved the quality of life of these patients.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77746427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of the continuous glucose monitoring system in the management of hypoglicemia in insulin autoimmune syndrome 连续血糖监测系统在胰岛素自身免疫综合征低血糖治疗中的应用

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0011

Andrada Raluca Pop, C. Ruscanu, G. Roman, I. Pașcanu

引用次数: 0

Abdominal wall metastases due to a squamous cell carcinoma of the lung: Case report and literature review 肺鳞状细胞癌引起的腹壁转移:病例报告及文献复习

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0010

C. Ioniță, I. Cojocaru, A. Gomotirceanu, B. Suciu, D. Milutin, Alexandru Ilie Butilcă, C. Molnar, I. Halmaciu

引用次数: 0

Pier abutment: Bridge the gap with non rigid connector - A clinical case report 墩式基台:用非刚性接头填补缺口- 1例临床报告

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0008

Vineet Sharma, K. Meena, B. Gurjar, Ramawatar Nagar

引用次数: 1

Comparative analysis of mandibular changes after orthodontic treatment with and without extraction of four premolars: A digital cephalometric study 正畸治疗前后下颌变化的比较分析:一项数字头颅测量研究

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0012

Anithab Alex, K. Shashidhar, M. Kuttappa, Krishna Nayak, Sai Kalyan Menta, A. Anushree

{"title":"Comparative analysis of mandibular changes after orthodontic treatment with and without extraction of four premolars: A digital cephalometric study","authors":"Anithab Alex, K. Shashidhar, M. Kuttappa, Krishna Nayak, Sai Kalyan Menta, A. Anushree","doi":"10.2478/amma-2022-0012","DOIUrl":"https://doi.org/10.2478/amma-2022-0012","url":null,"abstract":"Abstract Objective: To compare and evaluate the cephalometric hard and soft tissue changes of mandible after orthodontic treatment with and without extraction of four first premolar. Methodology: 60 individuals with Class I skeletal pattern were selected as per inclusion criteria. They were divided into two groups: 30 in the extraction group and 30 in the non-extraction group. Each group consists of 15 males and 15 females. Pre-treatment and post-treatment lateral cephalograms of the selected subjects were obtained, analysed and compared to assess the changes might have occurred. Descriptive statistics of the explanatory and outcome variables were calculated by mean and standard deviation for quantitative variables. Paired t test was applied to check the statistical difference of pre-treatment and post-treatment cephalometric parameters within the group (Extraction and non-extraction). Unpaired t test was used to check the statistical difference between extraction and non-extraction groups. The level of significance is set at 5%. Results: B point moved backward with lower incisor retraction. N-A-Pog shows a statistically significant decrease in the extraction group (P=0.003). B-NP shows a statistically significant decrease in extraction group (P=0.001). N- A’-Pog’ shows a statistically significant increase in non-extraction group (P=0.046). Soft tissue thickness in chin increases in extraction group and decreases in non-extraction group. Conclusion: The results indicate that premolar extraction will have a flattening effect on the midface. With proper diagnosis and treatment planning, premolar extractions have high potential to improve the facial profile.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72934207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non syndromic congenital agenesis of multiple permanent teeth: Case series and recent literature review 多颗恒牙无综合征先天性发育:病例系列及近期文献综述

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0013

Sowmya Sridhar, S. Uchil, A. Nayak, R. Ongole, B. Suprabha, Ashwin Rao, Y. Karuna

{"title":"Non syndromic congenital agenesis of multiple permanent teeth: Case series and recent literature review","authors":"Sowmya Sridhar, S. Uchil, A. Nayak, R. Ongole, B. Suprabha, Ashwin Rao, Y. Karuna","doi":"10.2478/amma-2022-0013","DOIUrl":"https://doi.org/10.2478/amma-2022-0013","url":null,"abstract":"Abstract Introduction: Hypodontia refers to the congenital absence of less than six teeth. This absence may be unilateral or bilateral. Though the congenital agenesis of bilateral mandibular/maxillary incisors has often been reported in literature, however, the congenital absence of bilateral mandibular and maxillary incisors, as well as the mandibular second molar-giving rise to a total of six missing permanent teeth in an apparently healthy individual has not been reported earlier. Case presentation: This case series presents two cases of a 10- and 11-year-old children with presence of retained deciduous anterior in both arches with absence of permanent successors and also aims to review the literature regarding etiology, clinical implications and management in such cases. Conclusions: It is essential that practitioners monitor the developing dentition with establishment of a proper review schedule. Non-eruption of the permanent tooth more than one year later than expected, or even after six months following the emergence of the contralateral tooth, warrants a high degree of suspicion. A multidisciplinary team, including pediatric, restorative and orthodontic specialists, is advised. In addition, prior to formulation of any treatment plan, due consideration to the general issues such as the patient’s systemic and oral health, motivation and expectations should be given.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79496607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Maturogenesis of an immature necrotic tooth with an extensive perirapical lesion using platelet rich fibrin 利用富含血小板的纤维蛋白对具有广泛根尖周围病变的未成熟坏死牙齿进行成熟发生

Acta Marisiensis - Seria Medica Pub Date : 2022-03-01 DOI: 10.2478/amma-2022-0001

Bhaswati Chakraborty, Ashwin Rao

{"title":"Maturogenesis of an immature necrotic tooth with an extensive perirapical lesion using platelet rich fibrin","authors":"Bhaswati Chakraborty, Ashwin Rao","doi":"10.2478/amma-2022-0001","DOIUrl":"https://doi.org/10.2478/amma-2022-0001","url":null,"abstract":"Abstract Introduction: Earlier, treatment of immature necrotic tooth focussed only on surgical endodontic management and apexification procedures. Regenerative endodontic therapies have called for a paradigm shift in management of such cases. Prognosis becomes challenging though at times due to chronicity of infection, inadequate disinfection of canal space and cytotoxic nature of irrigants used hindering the survival of the apical stem cells. Case presentation: This report highlights the management of a long-standing case of an immature necrotic tooth with an extensive periapical lesion in a 12 year old male patient. The protocol of regenerative endodontic procedure using platelet rich fibrin (PRF) was followed. Follow up visits at 1week, 3months and 12 months revealed a successful clinical and radiological outcome leading to progressive maturogenesis of the tooth. Conclusion: The case report favours the possibility of stem cells of apical papilla being viable even in chronic periapical lesions. Hence conservative approach involving regenerative endodontic therapies should always be sought for as first line of treatment in such cases.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84112056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rehabilitation of maxillary arch with attachment-retained reinforced single complete denture 附着体固位加固单口全口义齿修复上颌弓

Acta Marisiensis - Seria Medica Pub Date : 2022-03-01 DOI: 10.2478/amma-2022-0003

O. Andrei, D. Tărlungeanu, Ruxandra Mărgărit, G. Ciavoi, Adriana Bisoc

{"title":"Rehabilitation of maxillary arch with attachment-retained reinforced single complete denture","authors":"O. Andrei, D. Tărlungeanu, Ruxandra Mărgărit, G. Ciavoi, Adriana Bisoc","doi":"10.2478/amma-2022-0003","DOIUrl":"https://doi.org/10.2478/amma-2022-0003","url":null,"abstract":"Abstract Introduction: Fracture of maxillary complete denture is a common problem for dentists and denture wearers, occurring especially when it is opposing mandibular natural teeth or fixed and implant-sustained restorations; to prevent it, various methods and materials are available. Case presentation: This case is of a patient losing his old maxillary removable partial denture due to the mobility of the frontal abutments. Considering the age of the patient and the status of the mandibular arch, completely restored and having a mix of natural teeth, fixed and implant-sustained restorations, the functional and esthetic rehabilitation of the maxillary arch, and also the long-term resistance of the denture, are a serious prosthetic challenge. An association between ball attachments, metal-casted reinforcement and masking agents for both are described, underlying their role in the treatment’s succes. Conclusion: The age and health status of the patient and the situation of the mandibular arch imposed the construction of a functional, strong and stable maxillary denture; the technique described in this article offers a good functional and esthetical result and benefits the patient, even if the implant-prosthetic therapy is not available.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91122602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unified protocols for transdiagnostic treatment versus the Beckian’s approach of cognitive behavioral therapy for medical students with emotional disorders 统一的跨诊断治疗方案与贝克的认知行为治疗方法对情绪障碍医学生的影响

Acta Marisiensis - Seria Medica Pub Date : 2022-03-01 DOI: 10.2478/amma-2022-0002

C. Popa, P. Oláh, C. Cojocaru, Z. Jakab, D. Ghiga, Alina Schenk

{"title":"Unified protocols for transdiagnostic treatment versus the Beckian’s approach of cognitive behavioral therapy for medical students with emotional disorders","authors":"C. Popa, P. Oláh, C. Cojocaru, Z. Jakab, D. Ghiga, Alina Schenk","doi":"10.2478/amma-2022-0002","DOIUrl":"https://doi.org/10.2478/amma-2022-0002","url":null,"abstract":"Abstract Background: Emotional disorders are highly prevalent among medical students, impacting their academic performance and general quality of life. It was shown that cognitive-behavioral and emotion regulation strategies are efficient for reducing anxiety and depressive symptoms in young people. Objective: This study aims to compare the efficiency of standard individual Cognitive-Behavioral Therapy (CBT) to a group intervention based on the Unified Protocol for Transdiagnostic Treatment (UPTT) of emotional disorders in two groups of medical students with similar baseline characteristics. Method: The sample of this research was composed of 64 medical students in total, of which 34 were included in the CBT group (Mage= 19.5 years, SD= 0.96) and 30 were included in the UPTT group (Mage= 19.4 years, SD= 0.93). The level of irrational beliefs and emotional distress were measured before and after the interventions, which were carried out by certificated psychotherapists. Results: Statistically significant differences were observed between pre-test and post-test in both groups. The level of irrational beliefs dropped after the CBT (M=62.91, SD=21.30, p<0.05) and the UPTT intervention (M=67.33, SD=34.89, p<0.05), respectively. Similarly, the profile of emotional distress changed after the CBT (M=77.62, SD=16.97, p<0.05) and the UPTT intervention (M=68.77, SD=20.06, p<0.01). Conclusion: Psychological interventions relying on cognitive-behavioral approaches, including standard, individual psychotherapy and a group intervention designed according to a transdiagnostic protocol, are suitable methods for reducing emotional disorders among medical students.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74664764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Assessment of Failures in Generic Drug Development and Approval Procedure under Competitive Generic Drug Therapy and Patent Challenge Exclusivities Provided by the United States Food and Drug Administration 美国食品和药物管理局提供的竞争性仿制药治疗和专利挑战排他性下仿制药开发和批准程序失败的风险评估

Acta Marisiensis - Seria Medica Pub Date : 2022-03-01 DOI: 10.2478/amma-2022-0004

M. V. Reddy, Gnk Ganesh, B. Babu, Ramesh Jagadeesan, P. Mr

{"title":"Risk Assessment of Failures in Generic Drug Development and Approval Procedure under Competitive Generic Drug Therapy and Patent Challenge Exclusivities Provided by the United States Food and Drug Administration","authors":"M. V. Reddy, Gnk Ganesh, B. Babu, Ramesh Jagadeesan, P. Mr","doi":"10.2478/amma-2022-0004","DOIUrl":"https://doi.org/10.2478/amma-2022-0004","url":null,"abstract":"Abstract Objective: The United States Food and Drug Administration implemented two exclusivity programs Competitive generic therapy and Patent Challenge exclusivity to develop generic drugs, which provide a 180-day monopoly market for first generic applicants in the United States of America. The aim of the present study is to find the root cause of failures in developing and filing the first generic drugs under these exclusivities and to compare both the exclusivities to find the merits and demerits. Methods: We used descriptive statistics for data analysis of both the exclusivities and Risk assessment was conducted on 14 industries to find the root cause of failures in every stage of the approval procedure by FMECA (Failure mode, Effects and Criticality Analysis). Results: We found 44% of rejections in competitive generic therapy drugs and 30% of rejections in patent challenge exclusivity drugs. The risk analysis conducted on failures found that, in drug selection, 6% of failures are occurred due to rare diseases. In drug development, 9% of failures are occurred due to formulation failures. In pre-approval, 10% of failures are occurred due to secondary patents. In post-approval, 6% of failures are occurred due to product changes after approval. Conclusion: We hope this study can give an idea for small and medium companies in developing countries for the early development of generic drugs for life-threatening diseases.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73666261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1