Acta Marisiensis - Seria Medica最新文献_第7页

Reattachment of coronal tooth fragments: Aesthetic management of a complicated anterior maxillary crown fracture 冠状牙碎片再植:复杂上颌前冠骨折的美学处理

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0027

P. Shetty, Raksha Bhat, Arjun Kini

引用次数: 0

Computed tomography evaluation of diaphragm alterations in 20 critically ill COVID-19 positive patients 20例COVID-19阳性危重患者膈膜改变的ct评价

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0014

Oana-Elena Branea, A. R. Budeanu, Razvan-Gabriel Budeanu, Adrian Ștefan Chiuzan, Ioana Lăcrămioara Nazaret, S. Copotoiu, A. Lazăr

{"title":"Computed tomography evaluation of diaphragm alterations in 20 critically ill COVID-19 positive patients","authors":"Oana-Elena Branea, A. R. Budeanu, Razvan-Gabriel Budeanu, Adrian Ștefan Chiuzan, Ioana Lăcrămioara Nazaret, S. Copotoiu, A. Lazăr","doi":"10.2478/amma-2022-0014","DOIUrl":"https://doi.org/10.2478/amma-2022-0014","url":null,"abstract":"Abstract Objective: Diaphragmatic dysfunctions are multiple and critical illnesses often lead to the muscular atrophy that affects respiratory and peripheral muscles. The primary objective was to investigate diaphragm thickness in hospitalized patients. Secondary objectives were to assess clinical evolution and outcome. Methods: In a mean time period of 7.9 days, two different chest computed tomographies were used in order to examine diaphragm alterations of right and left diaphragm in 20 critically ill patients tested Real-Time Polymerase Chain Reaction positive to Severe Acute Respiratory Syndrome Coronavirus-2. Patients were divided in two groups (one group <5% decrease in diaphragm thickness and another group ≥5% decrease in diaphragm thickness). Results: Results showed that patients presented low 10 years predicted survival rate (Charlson Comorbidity Index > 7.7±3.08), marked inflammatory status (C-Reactive Protein = 98.22±73.35, Interleukine-6 = 168.31±255.28), high physiologic stress level (Neutrophil/Lymphocyte Ratio = 31.27±30.45), respectively altered acid-base equilibrium. Half of the investigated patients had decrease in diaphragm thickness by at least 5% (right diaphragm = −7.83%±11.11%, left diaphragm = −5.57%±10.63%). There were no statistically significant differences between those with decrease of diaphragm thickness and those without diaphragm thickness, regarding length of stay in Intensive Care Unit and in hospital, inflammatory markers, and acid-base disorders. Conclusions: Patients were admitted in Intensive Care Unit for acute respiratory failure and half of the investigated patients displayed diaphragm alterations at CT scan.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82923820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Is the pulmonary microbiome involved in lung cancer pathophysiology? 肺微生物群参与肺癌病理生理吗?

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0021

C. Budin, I. Cocuz, H. Sárközi, Adriana Sabău, B. Grigorescu

引用次数: 0

Nutrition in pregnancy – impact on anaemia in pregnant women 孕期营养——对孕妇贫血的影响

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0016

Oana Atomei, Paula Paraschiva Monor, B. Stana, M. Tarcea

{"title":"Nutrition in pregnancy – impact on anaemia in pregnant women","authors":"Oana Atomei, Paula Paraschiva Monor, B. Stana, M. Tarcea","doi":"10.2478/amma-2022-0016","DOIUrl":"https://doi.org/10.2478/amma-2022-0016","url":null,"abstract":"Abstract Aim: Most pregnant women can achieve their caloric and nutritional needs by careful food choices during pregnancy, but there are fairly common situations when pregnant women develop anaemia, which needs to be managed properly to avoid maternal-foetal complications. The main objective of the study was to identify the nutritional factors favoring the occurrence of iron deficiency anaemia in pregnant women. Methods: Data collection for the cross-sectional study was carried out using a questionnaire that provided information on nutrition and risk factors during pregnancy in a group of patients from Suceava. The questionnaire was given to pregnant women admitted to the Emergency County Hospital „Sfântul Ioan cel Nou” Suceava, Romania, between March and May 2017. Results: The anaemia occured in 46.3% of pregnant women. Although 22.2% of pregnant women received oral iron supplementation, effects on anaemia correction were not observed (p=0.02). We found that weight status did not influence anaemic status (p=0.51), and the presence of anaemia in pregnancy was independent of risk factors for pregnancy (smoking, p=0.05; alcohol consumption, p=0.66), iron absorption inhibitors in the diet (coffee, p=0.33; tea, p=0.53), water intake (p=0.52) or night eating (p=0.27). Conclusions: The results of dietary survey showed no direct link between the prevalence of anaemia and nutritional factors. Lower pre-pregnancy BMI was not associated with higher risk of iron deficiency anaemia, and daily iron supplementation during pregnancy did not meet the needs to counteract the anaemic syndrome. Nutrition education is particularly important for the prophylaxis of iron deficiency anaemia in pregnant women.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80818715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-plaque psoriasis: a single-clue diagnostic challenge 单斑块牛皮癣:单一线索诊断挑战

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0019

L. Decean, R. Ilieș, Andreea Sasu, Iulia Bârsan, A. Mihai

引用次数: 0

An overview of the microflora of the patients admitted in an Ear Nose and Throat tertiary hospital from Romania 罗马尼亚一家耳鼻喉三级医院住院患者的微生物群落概况

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0017

R. Togănel, R. L. Coșeriu, Camelia-Mirela Vintilă, A. Simion

{"title":"An overview of the microflora of the patients admitted in an Ear Nose and Throat tertiary hospital from Romania","authors":"R. Togănel, R. L. Coșeriu, Camelia-Mirela Vintilă, A. Simion","doi":"10.2478/amma-2022-0017","DOIUrl":"https://doi.org/10.2478/amma-2022-0017","url":null,"abstract":"Abstract Objective: The purpose of this retrospective study is to describe clinical, epidemiological and bacteriological findings on the Ear, Nose and Throat infections from patients admitted in a tertiary hospital from Romania, which might bring supportive data for the management of the ENT patients. Methods: Clinical data from 146 patients admitted in a clinic from Romania, between February 2016 and April 2018 were collected from the official registries of the Microbiology Laboratory, where the collected samples were processed by classical microbiological methods. Results: From 164 analyzed biological samples, 45.1% were suggestive for infection. Methicillin-sensitive Staphylococcus aureus was the most prevalent bacterial isolate (28.72%), followed by Pseudomonas aeruginosa (12.77%). There were 26 different species of microbes. Out of a total of 77 bacterial isolates, 62.33% were Gram positive and 37.66% Gram negative. The study showed that 11 ear discharge samples were positive in female and male patients. Upper respiratory tract exudates were positive on 3 females (21.4%) and on 17 males (28.8%). There were 7 positive pus samples from females, and from 25 males. Conclusions: Men were more affected by Ear Nose and Throat infections, caused by bacteria mostly from the genus Staphylococcus and Pseudomonas. More attention at the samples collection and a rigorous clinical examination should reduce the load on bacteriology laboratory. In specific cases, a negative bacteriological result can prove as an exclusion diagnostic.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83988838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clear or White? A RT-PCR plate comparison for SARS-CoV-2 diagnosis 清的还是白的?RT-PCR诊断SARS-CoV-2的比较

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0024

Elena Cristina Preda, V. Moldovan, O. Oprea

{"title":"Clear or White? A RT-PCR plate comparison for SARS-CoV-2 diagnosis","authors":"Elena Cristina Preda, V. Moldovan, O. Oprea","doi":"10.2478/amma-2022-0024","DOIUrl":"https://doi.org/10.2478/amma-2022-0024","url":null,"abstract":"Abstract Objective: During the COVID-19 pandemic, laboratories have used various extraction and amplification kits, associated with different auxiliary materials. This study aims to investigate how different types of plates may affect RT-PCR performance. Methods: Data on the positive controls (PCs) of RT-PCR runs for SARS-CoV-2 detection between December 2020 and April 2022 was collected retrospectively in the Molecular biology department of the County Emergency Clinical Hospital of Târgu Mureș’s clinical laboratory. The materials used consisted in MOLgen SARS-CoV-2 (Adaltis) and EliGene COVID19 CONFIRM 500 R amplification kits, 96-well full-skirted white and clear plates, and clear films. Microsoft Excel was used for the database and it included information about Cycle threshold (Ct) and maximum fluorescence. Statistical analysis, performed in MedCalc, consisted of Grubbs test, Kolmogorov–Smirnov Test, F test, T student test, and Mann-Whitney test to compare central tendencies. The significance threshold was set at p<0.05. Results: The Ct comparison for MOLgen kit white plates vs clear plates: FAM channel- U=1052.5, Z=2.07, p=0.038, medians for white plates and clear plates were 22.80 and 23.25, respectively; ROX channel- U=784, Z=3.21, p=0.001, medians 21.93 and 21.43, respectively; Cy5 channel- U=1028.5, Z=1.95, p=0.518, medians 22.12, 21.75, respectively. For EliGene kit: U=848.5, Z=3.27, p=0.001, medians 28.26 (white plates) and 28.0 (clear plates). Comparison of the maximum fluorescence reached on both kits with white and clear plates computed p values <0.0001. Conclusions: Between white and clear plates there are statistically significant differences considering Ct values and maximum read fluorescence, but with no impact on test outcome.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85430904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a low-grade glioma in an ischemic brain territory that evolved into a glioblastoma. A case report and brief literature review 脑缺血区域低级别胶质瘤的发展演变为胶质母细胞瘤。病例报告及简要文献回顾

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0015

Andrei-Cristian Fülöp, Zeno Opriș, Eugen-Francisc Fülöp, Ioana-Geanina Ghilință, Rita Szodorai, Attila Kövecsi

{"title":"Development of a low-grade glioma in an ischemic brain territory that evolved into a glioblastoma. A case report and brief literature review","authors":"Andrei-Cristian Fülöp, Zeno Opriș, Eugen-Francisc Fülöp, Ioana-Geanina Ghilință, Rita Szodorai, Attila Kövecsi","doi":"10.2478/amma-2022-0015","DOIUrl":"https://doi.org/10.2478/amma-2022-0015","url":null,"abstract":"Abstract Introduction: Glioblastoma is one of the most common and aggressive brain tumours with a very high mortality rate. It often evolves from a late or misdiagnosed astrocytoma. Stroke is one of the most common pathologies of the brain, affecting approximately 1.1 million Europeans each year. This article presents the sequential development of a low-grade astrocytoma in an ischemic brain territory into a high-grade glioblastoma. Case presentation: A 59-year-old patient presented to our hospital with severe headache and transient loss of balance and vision. Clinical findings and control imaging revealed the presence of an ischemic brain area in the left temporal lobe of the brain. Monthly brain magnetic resonance imaging (MRI) follow-up revealed the development of a low-grade astrocytoma in the ischemic territory, which later evolved into a glioblastoma. Conclusions: Patients who suffer from a stroke should be closely monitored via MRI to prevent the rare development of tumour pathology in the affected territory.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89613186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postpartum pancreatitis in young female – a rare case in the Emergency Department 年轻女性产后胰腺炎——急诊罕见病例

Acta Marisiensis - Seria Medica Pub Date : 2022-09-01 DOI: 10.2478/amma-2022-0018

A. Németh, Puiu Popescu

{"title":"Postpartum pancreatitis in young female – a rare case in the Emergency Department","authors":"A. Németh, Puiu Popescu","doi":"10.2478/amma-2022-0018","DOIUrl":"https://doi.org/10.2478/amma-2022-0018","url":null,"abstract":"Abstract Introduction: Acute pancreatitis is a condition that leads to multiple organ failure syndromes if not diagnosed and treated correctly. The most frequent causes of acute pancreatitis are gallstones, alcohol consumption, and elevated triglyceride serum level. Case Presentation: A 21-year-old female presented to the emergency department with epigastric pain, nausea, vomiting, and diaphoresis. The patient had a non-complicated vaginal birth four months prior, had no personal history of illness, reported no alcohol consumption, and had a slender body constitution. Laboratory tests outlined a white blood cell count of 22.000/µL, elevated neutrophil count, lactate dehydrogenase 294 U/L, and lipemic serum sample reported for chemistry laboratory test. In addition, the contrast-enhanced computed tomography scan revealed severe pancreatitis, with an intraabdominal fluid collection. Conclusions: This case report highlights the importance of correct early diagnosis in the postpartum and late postpartum period and raises awareness concerning the possibility of acute pancreatitis in a postpartum woman even if she does not have the two most common risk factors: gallstones or alcohol consumption.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82485991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethanolic extract of Edamame (Glycine max L. merril) enhance second degree burn wound healing trough modulating of hydroxiproline levels and increasing epithelial thickness 毛豆乙醇提取物(Glycine max L. merril)通过调节羟脯氨酸水平和增加上皮厚度来促进二度烧伤创面愈合

Acta Marisiensis - Seria Medica Pub Date : 2022-06-01 DOI: 10.2478/amma-2022-0007

I. Sutejo, Arifa Nur Hasanah, Faizah Ramadhani Sudarko

{"title":"Ethanolic extract of Edamame (Glycine max L. merril) enhance second degree burn wound healing trough modulating of hydroxiproline levels and increasing epithelial thickness","authors":"I. Sutejo, Arifa Nur Hasanah, Faizah Ramadhani Sudarko","doi":"10.2478/amma-2022-0007","DOIUrl":"https://doi.org/10.2478/amma-2022-0007","url":null,"abstract":"Abstract Objective: Burns has become a global health problem because it causes about 180.000 deaths worldwide every year. In developing countries, silver sulfadiazine cream is usually used as drug management for second-degree burns, but it is expensive, so several herbal treatments have developed recently. The seed of edamame has genistein compounds that can increase collagen synthesis. The antioxidant component also enhances the burn wound healing process. The study aims to prove the effectiveness of ethanolic extract of edamame’s seed in the second-degree burn wound healing process. Methods: Burn wound was made by applying hot aluminum (70 °C) coin on the skin rat. The negative control group (C-) was given Na-CMC 0.5%, the positive control group (C+) was given cream silver sulfadiazine, the treatment groups T1, T2, T3, and T4 were given an ethanolic extract of edamame with the concentration of 20%, 40%, 60%, and 80% for 15 days. Hydroxyproline levels were evaluated by hydroxyproline biochemistry assay, the epithelial thickness was observed on histopathological preparations with HE staining. Results: The results showed that the hydroxyproline levels on the 16th were modulated, while epithelial thickness was higher in the treatment group than in the control group (P<0.05). Conclusions: We conclude that the certain concentration of ethanolic extract of edamame (Glycine max L. Merril) was effectively enhanced the second-degree burn wound healing by modulating hydroxyproline levels and increasing epithelial thickness.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77625133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0