Acta Marisiensis - Seria Medica最新文献

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Cannabidiol in the context of sleeping disorders-induced oxidative stress 大麻二酚在睡眠障碍诱导的氧化应激中的作用
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0023
George Jîtcă, Bianca-Eugenia Ősz, C. Rusz, Amalia Pușcaș, A. Tero-Vescan, Mădălina-Georgiana Bătrînu, Ruxandra Ștefănescu
{"title":"Cannabidiol in the context of sleeping disorders-induced oxidative stress","authors":"George Jîtcă, Bianca-Eugenia Ősz, C. Rusz, Amalia Pușcaș, A. Tero-Vescan, Mădălina-Georgiana Bătrînu, Ruxandra Ștefănescu","doi":"10.2478/amma-2022-0023","DOIUrl":"https://doi.org/10.2478/amma-2022-0023","url":null,"abstract":"Abstract Sleep disorders can be the result of psychiatric or neurological conditions, such as post-traumatic stress disorders, depression, anxiety, Alzheimer’s disease, Parkinson’s disease. At the same time, changes in sleep, known as sleep disorders, are closely related to various metabolic dysfunctions, which in turn are the result of the generation of reactive oxygen species, or otherwise known as oxidative stress. For this reason, cannabinoid derivatives are increasingly used for this purpose. Among the most used are delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD). These agents interact with the endogenous endocannabinoid system, either by direct action on specific receptors, or by increasing the availability of endocannabinoids, modifying particular mental states (anxiety, depression). The results of the studies specified in this article provide promising evidence regarding the positive effects of CBD, which extend beyond the scope of sleep disorders, with possible applications also in the case of the accumulation of reactive oxygen species.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86729983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An evaluation of concordance between linear measurements obtained from conventional, digital and reconstructed three-dimensional printed orthodontic models: An in vitro study 评估从传统、数字和重建的三维打印正畸模型中获得的线性测量之间的一致性:一项体外研究
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0028
S. Shetty, S. Natarajan, Supriya Nambiar, Prithvi Shetty, K. Chengappa, Mukul Shetty
{"title":"An evaluation of concordance between linear measurements obtained from conventional, digital and reconstructed three-dimensional printed orthodontic models: An in vitro study","authors":"S. Shetty, S. Natarajan, Supriya Nambiar, Prithvi Shetty, K. Chengappa, Mukul Shetty","doi":"10.2478/amma-2022-0028","DOIUrl":"https://doi.org/10.2478/amma-2022-0028","url":null,"abstract":"Abstract Objective: To evaluate the potential use of digital and reconstructed three-dimensional printed models as an alternative to conventional plaster models by assessing the accuracy of their linear measurements. Methodology: Pre-treatment plaster models of 45 patients were selected from the archives of the Department of Orthodontics. Each physical plaster model was scanned and digitized using a three-dimensional (3D) laser surface scanning system (inEOS X5, Dentsply Sirona, Bensheim, Germany). The scanned STL files were later used to reconstruct models by 3D printing using Figure4® standalone 3D printer (3D systems, Rock Hill, South Carolina). Measurements of teeth 11 and 16, the transverse width of the upper jaw between the first molars (MM - intermolar width) and canines (CC - intercanine width) were done manually using a digital vernier caliper (Mitutoyo, Kawasaki, Japan), and the CAD Assistant software (Open cascade, Guyancourt, France). Intra examiner data, Intraobserver variability, and measurement accuracy were evaluated using Intraclass Correlation Coefficient (ICC) analysis was done using SPSS 20.0. Results: The intraclass correlation coefficients were >0.8 indicating high reproducibility and reliability. Significant differences were found between the physical and the digital models but to a small proportion which were deemed not clinically relevant. Conclusion: Both the digital models and reconstructed three-dimensional printed models using Figure4® technology were clinically permissible in terms of accuracy and reproducibility. The digital storage, transmission, and treatment planning in an environmentally friendly manner should promote digital over conventional records.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89389094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence based model for establishing the histopathological diagnostic of the cutaneous basal cell carcinoma 基于人工智能的皮肤基底细胞癌组织病理诊断模型的建立
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0020
Andrei Călin Dragomir, I. Cocuz, O. Cotoi, L. Azamfirei
{"title":"Artificial intelligence based model for establishing the histopathological diagnostic of the cutaneous basal cell carcinoma","authors":"Andrei Călin Dragomir, I. Cocuz, O. Cotoi, L. Azamfirei","doi":"10.2478/amma-2022-0020","DOIUrl":"https://doi.org/10.2478/amma-2022-0020","url":null,"abstract":"Abstract Introduction: Artificial intelligence (AI), a component of computer science, has the ability to process the multitude of medical data existing in the medical system around the world. The goal of our study is to build an AI model, based on Machine Learning, capable of assisting pathologists around the world in the diagnosis of the basal cell carcinoma of the skin. Material and Method: Our study is represented by the development of a Mask-RCNN (Mask Region-based Convolutional Neural Network) model, for the detection of cells with typical basal cell carcinoma tumoral changes. A number of 258 digitized histological images were used. The images emerged from Hematoxylin&Eosin stained pathology slides, diagnosed with cutaneous basal cell carcinoma between January 2018 and December 2021, at the Pathology Service of the Mureș County Clinical Hospital. Results: All the used images have the unique resolution of 2560x1920 pixels. For the learning process, we divided these images into two datasets: the learning dataset, representing 80% of the total images; and the test dataset, representing 20% of the total images. The AI model was trained using 1000 epochs with a learning rate of 0.00025 and only one classification category: basal cell carcinoma. Conclusions: The AI model successfully identified in 85% of the cases the areas with pathological changes present in the input images.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77587434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The effect of postprandial in vivo and experimental in vitro hyperlipidemia on human peripheral blood monocytes 餐后体内及实验外高脂血症对人外周血单核细胞的影响
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0026
I. Mănescu, Mariuca Manescu, Elena Cristina Preda, D. Manu, M. Dobreanu
{"title":"The effect of postprandial in vivo and experimental in vitro hyperlipidemia on human peripheral blood monocytes","authors":"I. Mănescu, Mariuca Manescu, Elena Cristina Preda, D. Manu, M. Dobreanu","doi":"10.2478/amma-2022-0026","DOIUrl":"https://doi.org/10.2478/amma-2022-0026","url":null,"abstract":"Abstract Objective: In this study, we aimed to investigate the effect of transient postprandial in vivo and prolonged experimental in vitro hyperlipidemia on human peripheral blood monocytes. Methods: Peripheral blood was collected from seven healthy subjects after an overnight fast and three hours after a standardized high-fat meal. Both fasting and postprandial samples were stained for surface markers CD14/CD11b and intracellular lipids using BODIPY493/503. Postprandial samples only were used for isolation of peripheral blood mononuclear cells that were further incubated overnight with postprandial hyperlipidemic autologous plasma, then stained as described above. All samples were analyzed on a FACSAria III flow cytometer. Results: Flow cytometric analysis revealed two monocyte populations (CD14+): CD14low and CD14high. In fasting, these populations show similar morphology (FSC/SSC), but different expressions of CD14, CD11b, and BODIPY493/503. At three hours postprandially, a moment of maximum hyperlipidemia, neither population suffered significant changes. After the 24-hour incubation, cell activation was observed in both populations: similar fold change increase in SSC, increase in FSC for CD14high cells only, similar foldchange increase in CD14, slightly higher foldchange increase in CD11b for CD14low monocytes, and significantly higher foldchange increase in lipid content for CD14high monocytes. CD14high monocytes appear to undergo a more intense activation than CD14low monocytes. Conclusions: We conclude that all monocytes react after prolonged in vitro exposure to plasma lipids, each subset having its own activation pattern. All monocyte types may play a role in inflammation and the development of plaques. Monocyte assays are a valuable tool for the investigation of atherosclerosis at the cellular level.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90894639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nano-scale surface modification of dental implants – An emerging boon for osseointegration and biofilm control 纳米级牙种植体表面修饰-骨整合和生物膜控制的新兴福音
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0029
Palekar Gouri Sachin, A. Uppoor, S. Nayak
{"title":"Nano-scale surface modification of dental implants – An emerging boon for osseointegration and biofilm control","authors":"Palekar Gouri Sachin, A. Uppoor, S. Nayak","doi":"10.2478/amma-2022-0029","DOIUrl":"https://doi.org/10.2478/amma-2022-0029","url":null,"abstract":"Abstract Implant therapy is a commonly based method of replacing missing teeth. A range of physical, chemical, and biological modifications have been applied to the surface of titanium implants to improve their biological performance and osseointegration outcomes. Implant surface characteristics play an important function in several peri-implant cellular and molecular mechanisms. Clinicians are commonly placing dental implants with various surface roughness and modifications including plasma-sprayed, acid-etched, blasted, oxidized, hydroxyapatite-coated, or combinations of these procedures. Surface modifications are to facilitate early osseointegration and to ensure a long-term bone-to-implant contact without substantial marginal bone loss can be accomplished. It is apparent that different modifications have a range of beneficial effects, it is essential to consider at what time point and in what conditions these effects occur. This article reviews existing surface modification technologies of mainstream dental implants and the correlation between implant surface coatings and their performance of osseointegration or anti-bacterial ability it needs to be evaluated.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75705962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Alpha adrenergic receptors in clinical practice – Present and future α肾上腺素能受体在临床实践中的现状和未来
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0030
Patrick Lechsner, Erika-Gyongyi Ban
{"title":"Alpha adrenergic receptors in clinical practice – Present and future","authors":"Patrick Lechsner, Erika-Gyongyi Ban","doi":"10.2478/amma-2022-0030","DOIUrl":"https://doi.org/10.2478/amma-2022-0030","url":null,"abstract":"Abstract In this review we discuss the adrenergic pathways for alpha 1 and alpha 2 receptors and the current as well as potential future medication targeting these receptors. Overall, there is ongoing research into a multitude of directions with a promising outlook for alpha 1 and alpha 2 adrenergic receptors. The alpha 1-adrenergic receptor subfamily is currently modulating only a modest number of nervous system functions due the fact, that only a relatively small number of selective commercial products are available. Chronic stress can affect the long-term depression of alpha 1 receptors. Recent studies are searching for new molecular targets which might act on these receptors. Presynaptic alpha 2 receptors play an important role in modulating release of several neurotransmitters in the central nervous system. The future of alpha 2 adrenergic receptors in clinical practice looks even more promising and versatile than that of alpha 1 adrenergic receptors. Alpha 2 adrenergic receptors show different responses, especially regarding hypertension and heart failure treatment, and current research suggests a genetic component as a cause, which is being explored further.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89659956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-surgical approach to a paediatric pilocytic astrocytoma with MRI follow-up. Case report and brief literature review 小儿毛细胞星形细胞瘤的非手术治疗及MRI随访。病例报告及简要文献复习
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0022
Andrei-Cristian Fülöp, Zeno Opriș, Eugen-Francisc Fülöp, Ioana-Geanina Ghilință, Cătălin Andrei Zăgan, Attila Kövecsi
{"title":"Non-surgical approach to a paediatric pilocytic astrocytoma with MRI follow-up. Case report and brief literature review","authors":"Andrei-Cristian Fülöp, Zeno Opriș, Eugen-Francisc Fülöp, Ioana-Geanina Ghilință, Cătălin Andrei Zăgan, Attila Kövecsi","doi":"10.2478/amma-2022-0022","DOIUrl":"https://doi.org/10.2478/amma-2022-0022","url":null,"abstract":"Abstract Introduction: Pilocytic astrocytoma is a common tumour in paediatric patients. A low-grade glioma, it is most commonly treated by surgery, with various post-surgical side effects. New methods of treatment and follow-up are constantly evolving to offer alternative options to paediatric patients whose nerve structures are developing. Case presentation: A 9-year-old patient diagnosed with a pilocytic astrocytoma by MRI and histopathological examination underwent a biopsy and evacuation procedure of the cystic component after which the patient’s condition improved significantly. The ‘wait-and-see’ approach using MRI instead of total surgical excision of the tumour was preferred, and the patient had favourable results on control imaging. Conclusions: Paediatric patients suffering from pilocytic astrocytoma with favourable imaging and histopathological features may consider MRI follow-up instead of surgical excision until the character of the tumour changes or until the brain has reached full development.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87538353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post maxillectomy definitive rehabilitation in post-covid mucormycosis patients using conventional and 3D printed obturator: A twin case report 使用常规和3D打印闭孔器治疗冠状病毒感染后毛霉菌病患者上颌切除术后的最终康复:一对双胞胎病例报告
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0032
Manu Rathee, S. Divakar, P. Jain, Sandeep Singh, S. Chahal
{"title":"Post maxillectomy definitive rehabilitation in post-covid mucormycosis patients using conventional and 3D printed obturator: A twin case report","authors":"Manu Rathee, S. Divakar, P. Jain, Sandeep Singh, S. Chahal","doi":"10.2478/amma-2022-0032","DOIUrl":"https://doi.org/10.2478/amma-2022-0032","url":null,"abstract":"Abstract Maxillectomy is the surgical removal or resection of the maxilla or upper jaw bone. Maxillectomy may be total or partial. It is performed during surgical treatment of cancer and infections (bacterial. fungal) of the oral cavity, nasal cavity and maxillary sinuses. Patient affected from post-Covid mucormycosis require local debridement or surgical resection resulting in maxillectomy. After surgery, patient has difficulty in mastication, speech, and swallowing because of communication between oral and nasal cavity. This may also give rise to psychological challenges and social exclusion. The prosthodontic rehabilitation of such patient using obturator provide a separation between oral and nasal cavity and improve the quality of life of the patient. There are various techniques and materials used for fabrication of definitive obturator. This article discusses the prosthodontic rehabilitation after maxillectomy in post-covid mucormycosis patients using obturator by conventional and 3D printed techniques.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85980938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hereditary hemochromatosis: Retrospective study on clinical data from Emergency County Hospital Mures 遗传性血色素沉着症:县急诊科临床资料的回顾性研究
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0031
Victor Sigmirean
{"title":"Hereditary hemochromatosis: Retrospective study on clinical data from Emergency County Hospital Mures","authors":"Victor Sigmirean","doi":"10.2478/amma-2022-0031","DOIUrl":"https://doi.org/10.2478/amma-2022-0031","url":null,"abstract":"Abstract Objective: Hereditary hemochromatosis, or primary hemochromatosis, is a recessive genetic liver disorder caused by iron accumulation in tissues. This study evaluates patients with hereditary hemochromatosis to determine correlations between clinical and laboratory data. Methods: The data analyzed in this study was gathered from the discharge records from 2019 to 2021 of the Gastroenterology Department of the Mures Country Emergency Clinical Hospital. 15 patients with hemochromatosis were sampled during the studied period. Results: Hepatic cirrhosis is present in 67% of the studied group of patients, 40% of patients presented hypertension and 20% of patients showed diabetes mellitus and portal hypertension. Positive correlations were obtained between serum iron and alkaline phosphatase (r=0.8536), between serum iron and lactate dehydrogenase (r=0.7381), and between serum iron and urea (r = 0.79). Positive, strong correlation between ferritin and serum iron (r=0.7719), GOT (r=0.778) and GPT (r=0.6108). total bilirubin and direct bilirubin (r = 0.85), between total bilirubin and GOT (r = 0.68) and GPT (r = 0.82). Conclusions: Excess iron stored is influencing organ function trough reactive oxygen species, the hepatic signs being a main participant in the clinical presentation, while serum iron cause damage to other tissues such as myocardium, pancreas and kidneys. Treatment for hemochromatosis includes phlebotomies, and iron chelation with Deferoxamine.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80116448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digitally designed fixed dental prosthesis with stress breaking effect using non-rigid connector for pier abutment: A case report 数字设计非刚性连接体用于桥墩基台具有应力断裂效果的固定义齿1例
Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI: 10.2478/amma-2022-0033
Manu Rathee, S. Divakar, P. Jain, Sandeep Singh, S. Chahal, S. Tomar
{"title":"Digitally designed fixed dental prosthesis with stress breaking effect using non-rigid connector for pier abutment: A case report","authors":"Manu Rathee, S. Divakar, P. Jain, Sandeep Singh, S. Chahal, S. Tomar","doi":"10.2478/amma-2022-0033","DOIUrl":"https://doi.org/10.2478/amma-2022-0033","url":null,"abstract":"Abstract Rigid connectors between pontic and retainer are preferred way of fabricating fixed partial dentures for many decades as they provide desirable strength, retention and stability to the prosthesis. However, it is not ideal for cases such as lone-standing abutments (pier abutment), maligned teeth where occlusal stress can extrude the restoration. This may lead to marginal leakage and secondary caries on the abutment teeth. Conversely, it is recommended to use non-rigid connectors which act as a stress breaker, where the tensile stresses are concentrated on the surrounding bone and not on the connectors. With advancement in digital technology in dentistry, the non-rigid connectors can be fabricated using additive manufacturing technology. The present case report discusses the Direct Metal Laser Sintering (DMLS) designed fixed dental prosthesis with key and keyway (Tenon and Mortise) non-rigid connector for rehabilitation of pier abutment in maxillary posterior region.","PeriodicalId":36282,"journal":{"name":"Acta Marisiensis - Seria Medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85453286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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